DE68928157D1 - Verfahren und Vorrichtung zur Bestimmung von in einer Flüssigkeitsprobe enthaltenen Teilchen - Google Patents

Verfahren und Vorrichtung zur Bestimmung von in einer Flüssigkeitsprobe enthaltenen Teilchen

Info

Publication number
DE68928157D1
DE68928157D1 DE68928157T DE68928157T DE68928157D1 DE 68928157 D1 DE68928157 D1 DE 68928157D1 DE 68928157 T DE68928157 T DE 68928157T DE 68928157 T DE68928157 T DE 68928157T DE 68928157 D1 DE68928157 D1 DE 68928157D1
Authority
DE
Germany
Prior art keywords
liquid sample
particles contained
determining particles
determining
contained
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE68928157T
Other languages
English (en)
Other versions
DE68928157T2 (de
Inventor
Ryo Miyake
Hiroshi Ohki
Isao Yamazaki
Toshio Kaneko
Hideyuki Horiuchi
Shinichi Sakuraba
Kaori Yasuda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hitachi Ltd
Original Assignee
Hitachi Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hitachi Ltd filed Critical Hitachi Ltd
Publication of DE68928157D1 publication Critical patent/DE68928157D1/de
Application granted granted Critical
Publication of DE68928157T2 publication Critical patent/DE68928157T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1081Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane
    • G01N35/1083Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane with one horizontal degree of freedom
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404Handling flow, e.g. hydrodynamic focusing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1081Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane
    • G01N35/1083Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane with one horizontal degree of freedom
    • G01N2035/1086Cylindrical, e.g. variable angle
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1004Cleaning sample transfer devices

Landscapes

  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Optical Measuring Cells (AREA)
DE68928157T 1988-09-19 1989-09-13 Verfahren und Vorrichtung zur Bestimmung von in einer Flüssigkeitsprobe enthaltenen Teilchen Expired - Lifetime DE68928157T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP63232462A JPH0718785B2 (ja) 1988-09-19 1988-09-19 フローセル装置

Publications (2)

Publication Number Publication Date
DE68928157D1 true DE68928157D1 (de) 1997-08-14
DE68928157T2 DE68928157T2 (de) 1998-02-26

Family

ID=16939667

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68928157T Expired - Lifetime DE68928157T2 (de) 1988-09-19 1989-09-13 Verfahren und Vorrichtung zur Bestimmung von in einer Flüssigkeitsprobe enthaltenen Teilchen

Country Status (4)

Country Link
US (1) US5079959A (de)
EP (1) EP0360487B1 (de)
JP (1) JPH0718785B2 (de)
DE (1) DE68928157T2 (de)

Families Citing this family (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2839560B2 (ja) * 1989-07-10 1998-12-16 株式会社日立製作所 粒子懸濁液混合装置,粒子懸濁液混合方法及び粒子計測装置
US5087295A (en) * 1990-06-13 1992-02-11 Becton Dickinson And Company Cleaning cycle for flow cytometers
JPH04115136A (ja) * 1990-09-05 1992-04-16 Hitachi Ltd 粒子計測装置
JP2972367B2 (ja) * 1991-03-20 1999-11-08 株式会社日立製作所 細胞分析装置
US5408891A (en) * 1992-12-17 1995-04-25 Beckman Instruments, Inc. Fluid probe washing apparatus and method
JP2763468B2 (ja) * 1992-12-25 1998-06-11 株式会社日立製作所 光散乱を用いた液体内の粒子分類装置
JP3052665B2 (ja) * 1993-01-26 2000-06-19 株式会社日立製作所 フローセル装置
EP0687203A4 (de) * 1993-03-05 1996-09-25 William H Thompson Gerät zum entleeren eines abschnitts einer blutprobe
JPH06273423A (ja) * 1993-03-18 1994-09-30 Daikin Ind Ltd 測定装置の測定時間短縮方法
ES2164076T3 (es) * 1993-09-29 2002-02-16 Becton Dickinson Co Aparato para preparacion y carga automaticas de muestras.
US5656499A (en) * 1994-08-01 1997-08-12 Abbott Laboratories Method for performing automated hematology and cytometry analysis
US5631165A (en) * 1994-08-01 1997-05-20 Abbott Laboratories Method for performing automated hematology and cytometry analysis
US5601234A (en) * 1994-08-01 1997-02-11 Abbott Laboratories Fluid nozzle and method of introducing a fluid
US5891734A (en) * 1994-08-01 1999-04-06 Abbott Laboratories Method for performing automated analysis
ES2251722T3 (es) * 1994-08-01 2006-05-01 Abbott Laboratories Procedimiento y aparato para la realizacion de analisis automatizados.
US5602039A (en) * 1994-10-14 1997-02-11 The University Of Washington Flow cytometer jet monitor system
US5602349A (en) * 1994-10-14 1997-02-11 The University Of Washington Sample introduction system for a flow cytometer
US6861265B1 (en) * 1994-10-14 2005-03-01 University Of Washington Flow cytometer droplet formation system
DE69532416T2 (de) * 1994-10-14 2004-12-02 University Of Washington, Seattle Methode und vorrichtung zur tröpfchenerzeugung mit hoher rate bei der durchfluss-cytometrie
JPH08178824A (ja) * 1994-12-21 1996-07-12 Toa Medical Electronics Co Ltd 粒子測定装置
EP0729021A1 (de) * 1995-02-25 1996-08-28 Roche Diagnostics GmbH Vorrichtung zur Bearbeitung von Proben auf Objektträgern
US6454945B1 (en) * 1995-06-16 2002-09-24 University Of Washington Microfabricated devices and methods
US5777177A (en) * 1996-02-07 1998-07-07 Arco Chemical Technology, L.P. Preparation of double metal cyanide-catalyzed polyols by continuous addition of starter
JPH09318522A (ja) * 1996-05-29 1997-12-12 Toa Medical Electronics Co Ltd 粒子検出器及び粒子分析装置
US6040906A (en) * 1996-07-11 2000-03-21 Harhay; Gregory P. Resonance raman spectroscopy for identifying and quantitating biomatter, organic, and inorganic analytes
WO1998034094A1 (en) 1997-01-31 1998-08-06 The Horticulture & Food Research Institute Of New Zealand Ltd. Optical apparatus
US6159739A (en) * 1997-03-26 2000-12-12 University Of Washington Device and method for 3-dimensional alignment of particles in microfabricated flow channels
US5819948A (en) * 1997-08-21 1998-10-13 Van Den Engh; Gerrit J. Particle separating apparatus and method
US6071689A (en) * 1997-12-31 2000-06-06 Xy, Inc. System for improving yield of sexed embryos in mammals
US6149867A (en) * 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
US6248590B1 (en) 1998-02-27 2001-06-19 Cytomation, Inc. Method and apparatus for flow cytometry
DE69942975D1 (de) * 1998-02-27 2011-01-05 Ventana Med Syst Inc Automatisierter molekularer pathologieapparat mit unabhängigen objektträgerwärmern
US7396508B1 (en) 2000-07-12 2008-07-08 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having independent slide heaters
AR018234A1 (es) 1998-07-30 2001-11-14 Xy Inc Metodo para producir una muestra para inseminacion de flujo de equinos y disposicion de citometria de flujo.
JP2000214070A (ja) * 1999-01-21 2000-08-04 Sysmex Corp シ―スフロ―セルとそれを用いた血液分析装置
US6228652B1 (en) 1999-02-16 2001-05-08 Coulter International Corp. Method and apparatus for analyzing cells in a whole blood sample
US7024316B1 (en) 1999-10-21 2006-04-04 Dakocytomation Colorado, Inc. Transiently dynamic flow cytometer analysis system
US7208265B1 (en) * 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
AU6303901A (en) * 2000-05-09 2001-11-20 Xy Inc High purity x-chromosome bearing and y-chromosome bearing populations of spermatozoa
AU2001269795B2 (en) * 2000-06-12 2006-07-20 Xy, Inc. Integrated herd management system utilizing isolated populations of x-chromosome bearing and y-chromosome bearing spermatozoa
US20040031071A1 (en) * 2000-10-05 2004-02-12 Xy, Inc. System of hysteroscopic insemination of mares
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
WO2002043574A2 (en) 2000-11-29 2002-06-06 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
US7012689B2 (en) 2001-05-17 2006-03-14 Dako Colorado, Inc. Flow cytometer with active automated optical alignment system
US20030211009A1 (en) * 2001-05-18 2003-11-13 Buchanan Kris S. Rapid multi-material sample input system
DE20117914U1 (de) * 2001-11-02 2003-03-13 Evotec OAI AG, 22525 Hamburg Probenabgabevorrichtung
CA2532376C (en) * 2002-08-01 2015-05-12 Colorado State University Research Foundation Low pressure sperm cell separation system
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
JP2005535346A (ja) * 2002-08-15 2005-11-24 エックスワイ,インコーポレイテッド 高分解能フローサイトメーター
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
DK1608963T3 (da) 2003-03-28 2010-04-06 Inguran Llc Apparatur og fremgangsmåder til tilvejebringelse af kønssorteret dyresperma
NZ544103A (en) 2003-05-15 2010-10-29 Xy Llc Efficient haploid cell sorting for flow cytometer systems
BRPI0509488A (pt) 2004-03-29 2007-09-11 Monsanto Technology Llc suspensões de esperma para seleção de populações enriquecidas carregando cromossomo x ou y
US7621282B2 (en) * 2004-06-17 2009-11-24 Abbott Laboratories, Inc. Probe washing cups and methods
AR049732A1 (es) 2004-07-22 2006-08-30 Monsanto Co Proceso para enriquecer una poblacion de celulas de esperma
WO2006015056A2 (en) 2004-07-27 2006-02-09 Dakocytomation Denmarks A/S Enhancing flow cytometry discrimination with geometric transformation
US7340957B2 (en) 2004-07-29 2008-03-11 Los Alamos National Security, Llc Ultrasonic analyte concentration and application in flow cytometry
US7618770B2 (en) * 2005-07-29 2009-11-17 Xy, Inc. Methods and apparatus for reducing protein content in sperm cell extenders
US7835000B2 (en) 2006-11-03 2010-11-16 Los Alamos National Security, Llc System and method for measuring particles in a sample stream of a flow cytometer or the like
US7867778B2 (en) * 2007-02-23 2011-01-11 Visiongate, Inc. Fluid focusing for positional control of a specimen for 3-D imaging
EP2479552B1 (de) 2007-04-02 2015-09-02 Acoustic Cytometry Systems, Inc. Verfahren zur verbesserten Analyse von in einem akustischen Feld fokussierten Zellen und Partikeln
US7837040B2 (en) 2007-04-09 2010-11-23 Los Alamos National Security, Llc Acoustic concentration of particles in fluid flow
US8083068B2 (en) 2007-04-09 2011-12-27 Los Alamos National Security, Llc Apparatus for separating particles utilizing engineered acoustic contrast capture particles
US8528406B2 (en) * 2007-10-24 2013-09-10 Los Alamos National Security, LLP Method for non-contact particle manipulation and control of particle spacing along an axis
US8263407B2 (en) 2007-10-24 2012-09-11 Los Alamos National Security, Llc Method for non-contact particle manipulation and control of particle spacing along an axis
US8266951B2 (en) 2007-12-19 2012-09-18 Los Alamos National Security, Llc Particle analysis in an acoustic cytometer
US8714014B2 (en) 2008-01-16 2014-05-06 Life Technologies Corporation System and method for acoustic focusing hardware and implementations
US9103782B2 (en) 2008-12-02 2015-08-11 Malvern Instruments Incorporated Automatic isothermal titration microcalorimeter apparatus and method of use
US8589851B2 (en) * 2009-12-15 2013-11-19 Memoir Systems, Inc. Intelligent memory system compiler
JP2011237201A (ja) 2010-05-06 2011-11-24 Sony Corp 微小粒子分取装置、マイクロチップ及びマイクロチップモジュール
WO2012057111A1 (ja) * 2010-10-27 2012-05-03 株式会社日立ハイテクノロジーズ 自動分析装置
JP2015222202A (ja) * 2014-05-22 2015-12-10 ソニー株式会社 粒子分析装置
JP6592765B2 (ja) * 2015-04-30 2019-10-23 トライボテックス株式会社 粒子計数装置
CN105973811A (zh) * 2016-04-28 2016-09-28 江苏英诺华医疗技术有限公司 具有血液分析和生化分析功能的分析仪及方法
EP3455003B1 (de) * 2016-05-11 2023-03-29 Siemens Healthcare Diagnostics Inc. Sondenwaschstation für analytische instrumentierung
JP2024518755A (ja) * 2021-04-23 2024-05-02 ベクトン・ディキンソン・アンド・カンパニー 分析器及び/又は選別器式のフロー式粒子分析器用の流体管理システム

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3523733A (en) * 1966-01-05 1970-08-11 Technicon Corp Method and apparatus for particle counting
CS151687B1 (de) * 1968-04-09 1973-11-19
AT278712B (de) * 1968-04-30 1970-02-10 H C Hans Dipl Ing Dr Dr List Zusatzeinrichtung für die Mikroblutgasanalyse
US3583230A (en) * 1968-06-12 1971-06-08 Sondell Research Dev Co Sample injection method and apparatus
US3661460A (en) * 1970-08-28 1972-05-09 Technicon Instr Method and apparatus for optical analysis of the contents of a sheathed stream
US4290011A (en) * 1978-05-18 1981-09-15 Particle Data, Inc. Particle length and volume comeasurement with controlled orientation
JPS54161388A (en) * 1978-06-10 1979-12-20 Toshiba Corp Automatic chemical analyzer
US4202747A (en) * 1978-07-06 1980-05-13 Beckman Instruments, Inc. Flow cell fluid and sample supply mechanism
JPS5535250A (en) * 1978-09-06 1980-03-12 Sumitomo Heavy Ind Ltd Turbidimeter
IT1130926B (it) * 1980-03-07 1986-06-18 Erba Strumentazione Dispositivo per il prelievo di campioni da analizzare,specialmente in capionatori automatici
GB2075672B (en) * 1980-04-17 1983-03-09 Chemlab Mfg Ltd Washpot for use with sampling probe
US4367043A (en) * 1980-05-05 1983-01-04 Leland Stanford Junior University Method and means for delivering liquid samples to a sample scanning device
JPS5782769A (en) * 1980-11-10 1982-05-24 Hitachi Ltd Automatic analyzing device
DE3049565C2 (de) * 1980-12-31 1985-05-30 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Vorrichtung zur Messung bestimmter Eigenschaften von in einer Partikelsuspension suspendierten Partikeln
JPS59107238A (ja) * 1982-12-10 1984-06-21 Hitachi Ltd 光散乱を用いた粒子測定装置
JPS59196440A (ja) * 1983-04-23 1984-11-07 Hiroaki Kimura 血液自動分注方法及びその装置
US4564803A (en) * 1983-08-29 1986-01-14 Coulter Corporation Method and apparatus for removing foreign matter from a flow cell of a particle study device
NL8303440A (nl) * 1983-10-07 1985-05-01 Philips Nv Doseerinrichting voor een meetvloeistof.
JPH0336914Y2 (de) * 1985-05-17 1991-08-05
JPS61270661A (ja) * 1985-05-24 1986-11-29 Hitachi Ltd 自動分析装置における試料処理方法
JPS61274242A (ja) * 1985-05-30 1986-12-04 Hitachi Electronics Eng Co Ltd 微粒子検出装置
US4790653A (en) * 1986-05-22 1988-12-13 Becton Dickinson And Company Housing for a flow cytometry apparatus with particle unclogging feature
EP0253519B1 (de) * 1986-07-11 1991-10-09 Beckman Instruments, Inc. Probenhandhabungsvorrichtung
JP2564558B2 (ja) * 1987-07-15 1996-12-18 マツダ株式会社 車両用電装品制御装置
US4917494A (en) * 1987-07-28 1990-04-17 Amherst Process Instruments, Inc. Beam forming apparatus for aerodynamic particle sizing system
JP2761385B2 (ja) * 1988-04-08 1998-06-04 東亜医用電子株式会社 免疫凝集測定装置
US4914966A (en) * 1988-12-15 1990-04-10 R. J. Reynolds Tobacco Company Automated ultrasonic probe holder for a sample feeder

Also Published As

Publication number Publication date
EP0360487A2 (de) 1990-03-28
EP0360487A3 (de) 1991-07-24
EP0360487B1 (de) 1997-07-09
DE68928157T2 (de) 1998-02-26
US5079959A (en) 1992-01-14
JPH0718785B2 (ja) 1995-03-06
JPH0280937A (ja) 1990-03-22

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