DE68928157D1 - Verfahren und Vorrichtung zur Bestimmung von in einer Flüssigkeitsprobe enthaltenen Teilchen - Google Patents
Verfahren und Vorrichtung zur Bestimmung von in einer Flüssigkeitsprobe enthaltenen TeilchenInfo
- Publication number
- DE68928157D1 DE68928157D1 DE68928157T DE68928157T DE68928157D1 DE 68928157 D1 DE68928157 D1 DE 68928157D1 DE 68928157 T DE68928157 T DE 68928157T DE 68928157 T DE68928157 T DE 68928157T DE 68928157 D1 DE68928157 D1 DE 68928157D1
- Authority
- DE
- Germany
- Prior art keywords
- liquid sample
- particles contained
- determining particles
- determining
- contained
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000007788 liquid Substances 0.000 title 1
- 239000002245 particle Substances 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1081—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane
- G01N35/1083—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane with one horizontal degree of freedom
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1081—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane
- G01N35/1083—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane with one horizontal degree of freedom
- G01N2035/1086—Cylindrical, e.g. variable angle
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1004—Cleaning sample transfer devices
Landscapes
- Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Dispersion Chemistry (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Optical Measuring Cells (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP63232462A JPH0718785B2 (ja) | 1988-09-19 | 1988-09-19 | フローセル装置 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68928157D1 true DE68928157D1 (de) | 1997-08-14 |
DE68928157T2 DE68928157T2 (de) | 1998-02-26 |
Family
ID=16939667
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE68928157T Expired - Lifetime DE68928157T2 (de) | 1988-09-19 | 1989-09-13 | Verfahren und Vorrichtung zur Bestimmung von in einer Flüssigkeitsprobe enthaltenen Teilchen |
Country Status (4)
Country | Link |
---|---|
US (1) | US5079959A (de) |
EP (1) | EP0360487B1 (de) |
JP (1) | JPH0718785B2 (de) |
DE (1) | DE68928157T2 (de) |
Families Citing this family (76)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2839560B2 (ja) * | 1989-07-10 | 1998-12-16 | 株式会社日立製作所 | 粒子懸濁液混合装置,粒子懸濁液混合方法及び粒子計測装置 |
US5087295A (en) * | 1990-06-13 | 1992-02-11 | Becton Dickinson And Company | Cleaning cycle for flow cytometers |
JPH04115136A (ja) * | 1990-09-05 | 1992-04-16 | Hitachi Ltd | 粒子計測装置 |
JP2972367B2 (ja) * | 1991-03-20 | 1999-11-08 | 株式会社日立製作所 | 細胞分析装置 |
US5408891A (en) * | 1992-12-17 | 1995-04-25 | Beckman Instruments, Inc. | Fluid probe washing apparatus and method |
JP2763468B2 (ja) * | 1992-12-25 | 1998-06-11 | 株式会社日立製作所 | 光散乱を用いた液体内の粒子分類装置 |
JP3052665B2 (ja) * | 1993-01-26 | 2000-06-19 | 株式会社日立製作所 | フローセル装置 |
EP0687203A4 (de) * | 1993-03-05 | 1996-09-25 | William H Thompson | Gerät zum entleeren eines abschnitts einer blutprobe |
JPH06273423A (ja) * | 1993-03-18 | 1994-09-30 | Daikin Ind Ltd | 測定装置の測定時間短縮方法 |
ES2164076T3 (es) * | 1993-09-29 | 2002-02-16 | Becton Dickinson Co | Aparato para preparacion y carga automaticas de muestras. |
US5656499A (en) * | 1994-08-01 | 1997-08-12 | Abbott Laboratories | Method for performing automated hematology and cytometry analysis |
US5631165A (en) * | 1994-08-01 | 1997-05-20 | Abbott Laboratories | Method for performing automated hematology and cytometry analysis |
US5601234A (en) * | 1994-08-01 | 1997-02-11 | Abbott Laboratories | Fluid nozzle and method of introducing a fluid |
US5891734A (en) * | 1994-08-01 | 1999-04-06 | Abbott Laboratories | Method for performing automated analysis |
ES2251722T3 (es) * | 1994-08-01 | 2006-05-01 | Abbott Laboratories | Procedimiento y aparato para la realizacion de analisis automatizados. |
US5602039A (en) * | 1994-10-14 | 1997-02-11 | The University Of Washington | Flow cytometer jet monitor system |
US5602349A (en) * | 1994-10-14 | 1997-02-11 | The University Of Washington | Sample introduction system for a flow cytometer |
US6861265B1 (en) * | 1994-10-14 | 2005-03-01 | University Of Washington | Flow cytometer droplet formation system |
DE69532416T2 (de) * | 1994-10-14 | 2004-12-02 | University Of Washington, Seattle | Methode und vorrichtung zur tröpfchenerzeugung mit hoher rate bei der durchfluss-cytometrie |
JPH08178824A (ja) * | 1994-12-21 | 1996-07-12 | Toa Medical Electronics Co Ltd | 粒子測定装置 |
EP0729021A1 (de) * | 1995-02-25 | 1996-08-28 | Roche Diagnostics GmbH | Vorrichtung zur Bearbeitung von Proben auf Objektträgern |
US6454945B1 (en) * | 1995-06-16 | 2002-09-24 | University Of Washington | Microfabricated devices and methods |
US5777177A (en) * | 1996-02-07 | 1998-07-07 | Arco Chemical Technology, L.P. | Preparation of double metal cyanide-catalyzed polyols by continuous addition of starter |
JPH09318522A (ja) * | 1996-05-29 | 1997-12-12 | Toa Medical Electronics Co Ltd | 粒子検出器及び粒子分析装置 |
US6040906A (en) * | 1996-07-11 | 2000-03-21 | Harhay; Gregory P. | Resonance raman spectroscopy for identifying and quantitating biomatter, organic, and inorganic analytes |
WO1998034094A1 (en) | 1997-01-31 | 1998-08-06 | The Horticulture & Food Research Institute Of New Zealand Ltd. | Optical apparatus |
US6159739A (en) * | 1997-03-26 | 2000-12-12 | University Of Washington | Device and method for 3-dimensional alignment of particles in microfabricated flow channels |
US5819948A (en) * | 1997-08-21 | 1998-10-13 | Van Den Engh; Gerrit J. | Particle separating apparatus and method |
US6071689A (en) * | 1997-12-31 | 2000-06-06 | Xy, Inc. | System for improving yield of sexed embryos in mammals |
US6149867A (en) * | 1997-12-31 | 2000-11-21 | Xy, Inc. | Sheath fluids and collection systems for sex-specific cytometer sorting of sperm |
US6248590B1 (en) | 1998-02-27 | 2001-06-19 | Cytomation, Inc. | Method and apparatus for flow cytometry |
DE69942975D1 (de) * | 1998-02-27 | 2011-01-05 | Ventana Med Syst Inc | Automatisierter molekularer pathologieapparat mit unabhängigen objektträgerwärmern |
US7396508B1 (en) | 2000-07-12 | 2008-07-08 | Ventana Medical Systems, Inc. | Automated molecular pathology apparatus having independent slide heaters |
AR018234A1 (es) | 1998-07-30 | 2001-11-14 | Xy Inc | Metodo para producir una muestra para inseminacion de flujo de equinos y disposicion de citometria de flujo. |
JP2000214070A (ja) * | 1999-01-21 | 2000-08-04 | Sysmex Corp | シ―スフロ―セルとそれを用いた血液分析装置 |
US6228652B1 (en) | 1999-02-16 | 2001-05-08 | Coulter International Corp. | Method and apparatus for analyzing cells in a whole blood sample |
US7024316B1 (en) | 1999-10-21 | 2006-04-04 | Dakocytomation Colorado, Inc. | Transiently dynamic flow cytometer analysis system |
US7208265B1 (en) * | 1999-11-24 | 2007-04-24 | Xy, Inc. | Method of cryopreserving selected sperm cells |
AU6303901A (en) * | 2000-05-09 | 2001-11-20 | Xy Inc | High purity x-chromosome bearing and y-chromosome bearing populations of spermatozoa |
AU2001269795B2 (en) * | 2000-06-12 | 2006-07-20 | Xy, Inc. | Integrated herd management system utilizing isolated populations of x-chromosome bearing and y-chromosome bearing spermatozoa |
US20040031071A1 (en) * | 2000-10-05 | 2004-02-12 | Xy, Inc. | System of hysteroscopic insemination of mares |
US7713687B2 (en) | 2000-11-29 | 2010-05-11 | Xy, Inc. | System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations |
WO2002043574A2 (en) | 2000-11-29 | 2002-06-06 | Xy, Inc. | System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations |
US7012689B2 (en) | 2001-05-17 | 2006-03-14 | Dako Colorado, Inc. | Flow cytometer with active automated optical alignment system |
US20030211009A1 (en) * | 2001-05-18 | 2003-11-13 | Buchanan Kris S. | Rapid multi-material sample input system |
DE20117914U1 (de) * | 2001-11-02 | 2003-03-13 | Evotec OAI AG, 22525 Hamburg | Probenabgabevorrichtung |
CA2532376C (en) * | 2002-08-01 | 2015-05-12 | Colorado State University Research Foundation | Low pressure sperm cell separation system |
US8486618B2 (en) | 2002-08-01 | 2013-07-16 | Xy, Llc | Heterogeneous inseminate system |
JP2005535346A (ja) * | 2002-08-15 | 2005-11-24 | エックスワイ,インコーポレイテッド | 高分解能フローサイトメーター |
US7169548B2 (en) | 2002-09-13 | 2007-01-30 | Xy, Inc. | Sperm cell processing and preservation systems |
DK1608963T3 (da) | 2003-03-28 | 2010-04-06 | Inguran Llc | Apparatur og fremgangsmåder til tilvejebringelse af kønssorteret dyresperma |
NZ544103A (en) | 2003-05-15 | 2010-10-29 | Xy Llc | Efficient haploid cell sorting for flow cytometer systems |
BRPI0509488A (pt) | 2004-03-29 | 2007-09-11 | Monsanto Technology Llc | suspensões de esperma para seleção de populações enriquecidas carregando cromossomo x ou y |
US7621282B2 (en) * | 2004-06-17 | 2009-11-24 | Abbott Laboratories, Inc. | Probe washing cups and methods |
AR049732A1 (es) | 2004-07-22 | 2006-08-30 | Monsanto Co | Proceso para enriquecer una poblacion de celulas de esperma |
WO2006015056A2 (en) | 2004-07-27 | 2006-02-09 | Dakocytomation Denmarks A/S | Enhancing flow cytometry discrimination with geometric transformation |
US7340957B2 (en) | 2004-07-29 | 2008-03-11 | Los Alamos National Security, Llc | Ultrasonic analyte concentration and application in flow cytometry |
US7618770B2 (en) * | 2005-07-29 | 2009-11-17 | Xy, Inc. | Methods and apparatus for reducing protein content in sperm cell extenders |
US7835000B2 (en) | 2006-11-03 | 2010-11-16 | Los Alamos National Security, Llc | System and method for measuring particles in a sample stream of a flow cytometer or the like |
US7867778B2 (en) * | 2007-02-23 | 2011-01-11 | Visiongate, Inc. | Fluid focusing for positional control of a specimen for 3-D imaging |
EP2479552B1 (de) | 2007-04-02 | 2015-09-02 | Acoustic Cytometry Systems, Inc. | Verfahren zur verbesserten Analyse von in einem akustischen Feld fokussierten Zellen und Partikeln |
US7837040B2 (en) | 2007-04-09 | 2010-11-23 | Los Alamos National Security, Llc | Acoustic concentration of particles in fluid flow |
US8083068B2 (en) | 2007-04-09 | 2011-12-27 | Los Alamos National Security, Llc | Apparatus for separating particles utilizing engineered acoustic contrast capture particles |
US8528406B2 (en) * | 2007-10-24 | 2013-09-10 | Los Alamos National Security, LLP | Method for non-contact particle manipulation and control of particle spacing along an axis |
US8263407B2 (en) | 2007-10-24 | 2012-09-11 | Los Alamos National Security, Llc | Method for non-contact particle manipulation and control of particle spacing along an axis |
US8266951B2 (en) | 2007-12-19 | 2012-09-18 | Los Alamos National Security, Llc | Particle analysis in an acoustic cytometer |
US8714014B2 (en) | 2008-01-16 | 2014-05-06 | Life Technologies Corporation | System and method for acoustic focusing hardware and implementations |
US9103782B2 (en) | 2008-12-02 | 2015-08-11 | Malvern Instruments Incorporated | Automatic isothermal titration microcalorimeter apparatus and method of use |
US8589851B2 (en) * | 2009-12-15 | 2013-11-19 | Memoir Systems, Inc. | Intelligent memory system compiler |
JP2011237201A (ja) | 2010-05-06 | 2011-11-24 | Sony Corp | 微小粒子分取装置、マイクロチップ及びマイクロチップモジュール |
WO2012057111A1 (ja) * | 2010-10-27 | 2012-05-03 | 株式会社日立ハイテクノロジーズ | 自動分析装置 |
JP2015222202A (ja) * | 2014-05-22 | 2015-12-10 | ソニー株式会社 | 粒子分析装置 |
JP6592765B2 (ja) * | 2015-04-30 | 2019-10-23 | トライボテックス株式会社 | 粒子計数装置 |
CN105973811A (zh) * | 2016-04-28 | 2016-09-28 | 江苏英诺华医疗技术有限公司 | 具有血液分析和生化分析功能的分析仪及方法 |
EP3455003B1 (de) * | 2016-05-11 | 2023-03-29 | Siemens Healthcare Diagnostics Inc. | Sondenwaschstation für analytische instrumentierung |
JP2024518755A (ja) * | 2021-04-23 | 2024-05-02 | ベクトン・ディキンソン・アンド・カンパニー | 分析器及び/又は選別器式のフロー式粒子分析器用の流体管理システム |
Family Cites Families (27)
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US3523733A (en) * | 1966-01-05 | 1970-08-11 | Technicon Corp | Method and apparatus for particle counting |
CS151687B1 (de) * | 1968-04-09 | 1973-11-19 | ||
AT278712B (de) * | 1968-04-30 | 1970-02-10 | H C Hans Dipl Ing Dr Dr List | Zusatzeinrichtung für die Mikroblutgasanalyse |
US3583230A (en) * | 1968-06-12 | 1971-06-08 | Sondell Research Dev Co | Sample injection method and apparatus |
US3661460A (en) * | 1970-08-28 | 1972-05-09 | Technicon Instr | Method and apparatus for optical analysis of the contents of a sheathed stream |
US4290011A (en) * | 1978-05-18 | 1981-09-15 | Particle Data, Inc. | Particle length and volume comeasurement with controlled orientation |
JPS54161388A (en) * | 1978-06-10 | 1979-12-20 | Toshiba Corp | Automatic chemical analyzer |
US4202747A (en) * | 1978-07-06 | 1980-05-13 | Beckman Instruments, Inc. | Flow cell fluid and sample supply mechanism |
JPS5535250A (en) * | 1978-09-06 | 1980-03-12 | Sumitomo Heavy Ind Ltd | Turbidimeter |
IT1130926B (it) * | 1980-03-07 | 1986-06-18 | Erba Strumentazione | Dispositivo per il prelievo di campioni da analizzare,specialmente in capionatori automatici |
GB2075672B (en) * | 1980-04-17 | 1983-03-09 | Chemlab Mfg Ltd | Washpot for use with sampling probe |
US4367043A (en) * | 1980-05-05 | 1983-01-04 | Leland Stanford Junior University | Method and means for delivering liquid samples to a sample scanning device |
JPS5782769A (en) * | 1980-11-10 | 1982-05-24 | Hitachi Ltd | Automatic analyzing device |
DE3049565C2 (de) * | 1980-12-31 | 1985-05-30 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | Vorrichtung zur Messung bestimmter Eigenschaften von in einer Partikelsuspension suspendierten Partikeln |
JPS59107238A (ja) * | 1982-12-10 | 1984-06-21 | Hitachi Ltd | 光散乱を用いた粒子測定装置 |
JPS59196440A (ja) * | 1983-04-23 | 1984-11-07 | Hiroaki Kimura | 血液自動分注方法及びその装置 |
US4564803A (en) * | 1983-08-29 | 1986-01-14 | Coulter Corporation | Method and apparatus for removing foreign matter from a flow cell of a particle study device |
NL8303440A (nl) * | 1983-10-07 | 1985-05-01 | Philips Nv | Doseerinrichting voor een meetvloeistof. |
JPH0336914Y2 (de) * | 1985-05-17 | 1991-08-05 | ||
JPS61270661A (ja) * | 1985-05-24 | 1986-11-29 | Hitachi Ltd | 自動分析装置における試料処理方法 |
JPS61274242A (ja) * | 1985-05-30 | 1986-12-04 | Hitachi Electronics Eng Co Ltd | 微粒子検出装置 |
US4790653A (en) * | 1986-05-22 | 1988-12-13 | Becton Dickinson And Company | Housing for a flow cytometry apparatus with particle unclogging feature |
EP0253519B1 (de) * | 1986-07-11 | 1991-10-09 | Beckman Instruments, Inc. | Probenhandhabungsvorrichtung |
JP2564558B2 (ja) * | 1987-07-15 | 1996-12-18 | マツダ株式会社 | 車両用電装品制御装置 |
US4917494A (en) * | 1987-07-28 | 1990-04-17 | Amherst Process Instruments, Inc. | Beam forming apparatus for aerodynamic particle sizing system |
JP2761385B2 (ja) * | 1988-04-08 | 1998-06-04 | 東亜医用電子株式会社 | 免疫凝集測定装置 |
US4914966A (en) * | 1988-12-15 | 1990-04-10 | R. J. Reynolds Tobacco Company | Automated ultrasonic probe holder for a sample feeder |
-
1988
- 1988-09-19 JP JP63232462A patent/JPH0718785B2/ja not_active Expired - Fee Related
-
1989
- 1989-09-08 US US07/404,559 patent/US5079959A/en not_active Expired - Lifetime
- 1989-09-13 DE DE68928157T patent/DE68928157T2/de not_active Expired - Lifetime
- 1989-09-13 EP EP89309279A patent/EP0360487B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0360487A2 (de) | 1990-03-28 |
EP0360487A3 (de) | 1991-07-24 |
EP0360487B1 (de) | 1997-07-09 |
DE68928157T2 (de) | 1998-02-26 |
US5079959A (en) | 1992-01-14 |
JPH0718785B2 (ja) | 1995-03-06 |
JPH0280937A (ja) | 1990-03-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |