ES2164076T3 - Aparato para preparacion y carga automaticas de muestras. - Google Patents
Aparato para preparacion y carga automaticas de muestras.Info
- Publication number
- ES2164076T3 ES2164076T3 ES94114927T ES94114927T ES2164076T3 ES 2164076 T3 ES2164076 T3 ES 2164076T3 ES 94114927 T ES94114927 T ES 94114927T ES 94114927 T ES94114927 T ES 94114927T ES 2164076 T3 ES2164076 T3 ES 2164076T3
- Authority
- ES
- Spain
- Prior art keywords
- sample
- incubation
- reagent
- tube
- probe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000523 sample Substances 0.000 abstract 16
- 238000011534 incubation Methods 0.000 abstract 12
- 239000003153 chemical reaction reagent Substances 0.000 abstract 7
- 238000002347 injection Methods 0.000 abstract 3
- 239000007924 injection Substances 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 238000005406 washing Methods 0.000 abstract 2
- IHPYMWDTONKSCO-UHFFFAOYSA-N 2,2'-piperazine-1,4-diylbisethanesulfonic acid Chemical compound OS(=O)(=O)CCN1CCN(CCS(O)(=O)=O)CC1 IHPYMWDTONKSCO-UHFFFAOYSA-N 0.000 abstract 1
- 239000007990 PIPES buffer Substances 0.000 abstract 1
- 239000012530 fluid Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000005070 sampling Methods 0.000 abstract 1
- 239000007921 spray Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1081—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane
- G01N35/1083—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane with one horizontal degree of freedom
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1079—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices with means for piercing stoppers or septums
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/10—Devices for withdrawing samples in the liquid or fluent state
- G01N1/14—Suction devices, e.g. pumps; Ejector devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/38—Diluting, dispersing or mixing samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00346—Heating or cooling arrangements
- G01N2035/00356—Holding samples at elevated temperature (incubation)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
- G01N2035/00742—Type of codes
- G01N2035/00752—Type of codes bar codes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1032—Dilution or aliquotting
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1081—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane
- G01N35/1083—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane with one horizontal degree of freedom
- G01N2035/1086—Cylindrical, e.g. variable angle
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/025—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1004—Cleaning sample transfer devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
- G01N35/1097—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers characterised by the valves
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
UN SISTEMA AUTOMATIZADO PARA PREPARAR MUESTRAS, Y ENTONCES CARGAR LAS MUESTRAS A UN ANALIZADOR QUE INCLUYE UN CARRUSEL PARA MUESTRA QUE COMBINA Y HACE ROTAR UNA PLURALIDAD DE TUBOS DE ENSAYO PARA UNA ESTACION DE ASPIRACION. UNA MUESTRA ES ASPIRADA DESDE EL TUBO, Y DIRIGIDA A LO LARGO CON UN REACTIVO DE ENSAYO EN UN TUBO DE INCUBACION. UNA PLURALIDAD DE TUBOS DE INCUBACION ESTAN INCLUIDOS SOBRE UN CARRUSEL DE TUBOS DE INCUBACION, Y UNA SONDA REACTIVA ASPIRA UN REACTIVO Y DISPENSA EL REACTIVO A LO LARGO CON LA MUESTRA DENTRO DEL TUBO DE INCUBACION. UN TUBO DE INCUBACION ES CONTINUAMENTE ROTADO PARA UNA SONDA DE INYECCION QUE ELIMINA UNA PORCION DE LA MUESTRA Y REACTIVO DESPUES DE QUE LA MUESTRA HAYA TENIDO TIEMPO PARA INCUBAR. LA SONDA DE INYECCION LIBERA LA MUESTRA RETIRADA A UNA PUERTA DE INYECCION PARA UN SISTEMA DE ANALISIS. EL SISTEMA DE ANALISIS UTILIZA UNA TECNICA DE PRUEBA CONOCIDA PARA PROBAR LA MUESTRA. EL SISTEMA PUEDE INCLUIR UNA ESTACION PARA DISPENSAR UN AGENTE CAUSANTE DE LISISO UN AGENTE DE AMORTIGUACION EN EL TUBO DE INCUBACION DESPUES QUE LA SONDA REACTIVA HAYA DISPENSADO EL REACTIVO Y MUESTRA DENTRO DEL TUBO DE INCUBACION, Y ANTES QUE LA SONDA DE INYECCION RETIRE LA MUESTRA. ESTACIONES DE LAVADO ESTAN DISPUESTAS PARA LAVAR LAS DIVERSAS SONDAS. ADICIONALMENTE, SONDAS DE LAVADO SON INCLUIDAS PARA LAVAR LOS TUBOS DE INCUBACION DESPUES QUE LA MUESTRA HAYA SIDO RETIRADA POR LA SONDA DE PRUEBA. POR CONSIGUIENTE, EL SISTEMA PUEDE OPERAR AUTOMATICAMENTE Y CONTINUAMENTE PARA RETIRAR MUESTRAS DE DICHOS TUBOS DE MUESTRA, PREPARAR MUESTRAS EN EL TUBO DE INCUBACION, Y ESTAS MUESTRAS A UN ANALIZADOR. LOS TUBOS DE INCUBACION DE MUESTRA SON LIMPIADOS PARA REUTILIZACION. EN OTRA CARACTERISTICA DE LA INVENCION, UNA BOMBA PARA IMPULSAR EL REACTIVO Y LA MUESTRA DENTRO DEL TUBO DE INCUBACION INCLUYE UNA CONEXION PARA AIRE QUE FACILITA EL MOVIMIENTO DE LOS FLUIDOS DENTRO DE LOS TUBOS DE INCUBACION.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12923793A | 1993-09-29 | 1993-09-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2164076T3 true ES2164076T3 (es) | 2002-02-16 |
Family
ID=22439037
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94114927T Expired - Lifetime ES2164076T3 (es) | 1993-09-29 | 1994-09-22 | Aparato para preparacion y carga automaticas de muestras. |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP0645631B1 (es) |
DE (1) | DE69429230T2 (es) |
ES (1) | ES2164076T3 (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AUPN762196A0 (en) * | 1996-01-17 | 1996-02-08 | Australian Biomedical Corporation Limited | Specimen preparation apparatus |
US5856194A (en) | 1996-09-19 | 1999-01-05 | Abbott Laboratories | Method for determination of item of interest in a sample |
FI105784B (fi) * | 1998-09-14 | 2000-10-13 | Wallac Oy | Menetelmä ja laite näytteen ottamiseksi suljetusta koeputkesta |
DE10002475C1 (de) | 2000-01-21 | 2001-05-31 | Roche Diagnostics Gmbh | Analysegerät zur Analyse von Proben |
GB0004456D0 (en) | 2000-02-26 | 2000-04-19 | Glaxo Group Ltd | Medicament dispenser |
US6809804B1 (en) | 2000-05-11 | 2004-10-26 | Becton, Dickinson And Company | System and method for providing improved event reading and data processing capabilities in a flow cytometer |
GB0012465D0 (en) | 2000-05-24 | 2000-07-12 | Glaxo Group Ltd | Monitoring method |
GB0013619D0 (en) | 2000-06-06 | 2000-07-26 | Glaxo Group Ltd | Sample container |
US7191777B2 (en) | 2000-07-15 | 2007-03-20 | Glaxo Group Limited | Medicament dispenser |
EP1399724B1 (en) | 2001-06-13 | 2007-08-22 | Kenneth F. Uffenheimer | Automated fluid handling system and method |
WO2005114224A1 (en) * | 2004-05-07 | 2005-12-01 | Novasite Pharmaceuticals, Inc. | Direct mixing and injection for high throughput fluidic systems |
US7858040B2 (en) | 2004-05-07 | 2010-12-28 | Saryna Biotechnologies Llc | Direct mixing and injection for high throughput fluidic systems |
CN101201349B (zh) * | 2005-03-17 | 2011-10-12 | 希森美康株式会社 | 试料分析装置和试料分析方法以及血液分析装置 |
US9243993B2 (en) | 2005-03-17 | 2016-01-26 | Sysmex Corporation | Sample analyzer and sample analyzing method |
CN102879258A (zh) * | 2011-07-15 | 2013-01-16 | 江苏美诚生物科技有限公司 | 新型试剂高效自动混匀装置 |
IN2014MN01746A (es) | 2012-02-24 | 2015-07-10 | Instrunor As | |
CN102661888B (zh) * | 2012-05-18 | 2014-07-30 | 山东美医林电子仪器有限公司 | 一种适用于血流变检测的全血自动层吸取样混匀方法及装置 |
JP6680610B2 (ja) * | 2016-04-28 | 2020-04-15 | シスメックス株式会社 | 前処理装置及び検体分析装置 |
EP3864419A4 (en) * | 2018-10-08 | 2022-07-13 | Accure Health Inc. | AUTOMATED DOSAGE PROCESSING METHODS AND SYSTEMS |
CN109655627B (zh) * | 2018-12-17 | 2024-06-25 | 宁波海壹生物科技有限公司 | 一种带孵育功能的清洗装置 |
CN111521772B (zh) * | 2019-02-02 | 2021-12-07 | 深圳迎凯生物科技有限公司 | 液体分配方法和免疫分析方法 |
CN113219193B (zh) * | 2020-01-21 | 2024-03-19 | 深圳迎凯生物科技有限公司 | 样本分析方法和样本分析装置 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2076797A5 (es) * | 1970-01-28 | 1971-10-15 | Girolami Antoine | |
JPS56154667A (en) * | 1980-05-01 | 1981-11-30 | Olympus Optical Co Ltd | Partial injection |
US4387076A (en) * | 1981-10-14 | 1983-06-07 | Coulter Electronics, Inc. | Sample feeding arrangement |
US4517302A (en) * | 1982-11-15 | 1985-05-14 | Technicon Instruments Corporation | Continuous flow metering apparatus |
WO1986002626A1 (en) * | 1984-10-23 | 1986-05-09 | Donald Earl Burg | Snap-in cartridge diluter |
US5133936A (en) * | 1988-09-07 | 1992-07-28 | Hitachi, Ltd. | Constant-temperature air type automatic analysis apparatus |
JPH0718785B2 (ja) * | 1988-09-19 | 1995-03-06 | 株式会社日立製作所 | フローセル装置 |
US5167926A (en) * | 1989-09-13 | 1992-12-01 | Kabushiki Kaisha Tiyoda Seisakusho | Apparatus for pretreating cells for flow cytometry |
-
1994
- 1994-09-22 EP EP19940114927 patent/EP0645631B1/en not_active Expired - Lifetime
- 1994-09-22 DE DE1994629230 patent/DE69429230T2/de not_active Expired - Lifetime
- 1994-09-22 ES ES94114927T patent/ES2164076T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE69429230T2 (de) | 2002-07-18 |
DE69429230D1 (de) | 2002-01-10 |
EP0645631A2 (en) | 1995-03-29 |
EP0645631A3 (en) | 1996-02-07 |
EP0645631B1 (en) | 2001-11-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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