DE68925044T2 - Herstellung von Fusionsproteinen oder -polypeptiden - Google Patents

Herstellung von Fusionsproteinen oder -polypeptiden

Info

Publication number
DE68925044T2
DE68925044T2 DE68925044T DE68925044T DE68925044T2 DE 68925044 T2 DE68925044 T2 DE 68925044T2 DE 68925044 T DE68925044 T DE 68925044T DE 68925044 T DE68925044 T DE 68925044T DE 68925044 T2 DE68925044 T2 DE 68925044T2
Authority
DE
Germany
Prior art keywords
polypeptide
recombinant vector
fusion protein
host
dna sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68925044T
Other languages
English (en)
Other versions
DE68925044D1 (de
Inventor
Per-Ake Nygren
Lars Abrahmsen
Mathias Uhlen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE68925044D1 publication Critical patent/DE68925044D1/de
Publication of DE68925044T2 publication Critical patent/DE68925044T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445—Plasmodium
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/034—Fusion polypeptide containing a localisation/targetting motif containing a motif for targeting to the periplasmic space of Gram negative bacteria as a soluble protein, i.e. signal sequence should be cleaved
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/705—Fusion polypeptide containing domain for protein-protein interaction containing a protein-A fusion

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE68925044T 1988-02-05 1989-02-02 Herstellung von Fusionsproteinen oder -polypeptiden Expired - Fee Related DE68925044T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8800378A SE501169C2 (sv) 1988-02-05 1988-02-05 Framställning av serumalbuminbindande fusionsproteiner vilka innehåller protein G-domäner

Publications (2)

Publication Number Publication Date
DE68925044D1 DE68925044D1 (de) 1996-01-25
DE68925044T2 true DE68925044T2 (de) 1996-05-09

Family

ID=20371279

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68925044T Expired - Fee Related DE68925044T2 (de) 1988-02-05 1989-02-02 Herstellung von Fusionsproteinen oder -polypeptiden

Country Status (7)

Country Link
EP (1) EP0327522B1 (de)
JP (1) JP3026812B2 (de)
AT (1) ATE131494T1 (de)
DE (1) DE68925044T2 (de)
ES (1) ES2080759T3 (de)
GR (1) GR3018617T3 (de)
SE (1) SE501169C2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69101486T2 (de) * 1990-01-24 1994-08-04 Upjohn Co Verfahren zur reinigung rekombinanter polypeptide.
US5595887A (en) * 1990-07-16 1997-01-21 Bionebraska, Inc. Purification directed cloning of peptides using carbonic anhydrase as the affinity binding segment
DE4037837A1 (de) * 1990-11-28 1992-06-04 Behringwerke Ag Zellfreie rezeptorbindungsteste, ihre herstellung und verwendung
FR2726471B1 (fr) * 1994-11-07 1997-01-31 Pf Medicament Procede pour ameliorer l'immunogenicite d'un compose immunogene ou d'un haptene et application a la preparation de vaccins
GB9509336D0 (en) * 1995-05-09 1995-06-28 Dynal As Chemical method
GB9716790D0 (en) 1997-08-07 1997-10-15 Creative Peptides Sweden Ab Recombinant DNA molecules comprising multimeric copies of a gene sequence and expression thereof
EP1900754A1 (de) * 2006-09-18 2008-03-19 Institut National De La Sante Et De La Recherche Medicale (Inserm) Fusionsprotein enthaltend zwei IgG bindende Domänen des G Proteins von Streptococcus

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8300693L (sv) * 1983-02-09 1984-08-10 Sven Lofdahl Sett att framstella och isolera proteiner och polypeptider samt en hybridvektor for detta
SE459662B (sv) * 1986-03-21 1989-07-24 Pharmacia Ab Hybrid-dna-molekyl som kodar foer ett protein med samma igg specificitet som protein g, plasmid innehaallande densamma samt foerfarande foer framstaellning av proteinet

Also Published As

Publication number Publication date
SE8800378D0 (sv) 1988-02-05
JP3026812B2 (ja) 2000-03-27
JPH025887A (ja) 1990-01-10
EP0327522A3 (en) 1990-07-04
ES2080759T3 (es) 1996-02-16
EP0327522A2 (de) 1989-08-09
DE68925044D1 (de) 1996-01-25
GR3018617T3 (en) 1996-04-30
ATE131494T1 (de) 1995-12-15
SE8800378L (sv) 1989-08-06
EP0327522B1 (de) 1995-12-13
SE501169C2 (sv) 1994-11-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee