DE68909245T2 - Übergangsmetall-stickstoffkomplex enthaltendes radiopharmazeutisches produkt mit einer neigung zum herzgewebe. - Google Patents

Übergangsmetall-stickstoffkomplex enthaltendes radiopharmazeutisches produkt mit einer neigung zum herzgewebe.

Info

Publication number
DE68909245T2
DE68909245T2 DE89913235T DE68909245T DE68909245T2 DE 68909245 T2 DE68909245 T2 DE 68909245T2 DE 89913235 T DE89913235 T DE 89913235T DE 68909245 T DE68909245 T DE 68909245T DE 68909245 T2 DE68909245 T2 DE 68909245T2
Authority
DE
Germany
Prior art keywords
inclination
transition metal
heart tissue
complex containing
metal nitrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE89913235T
Other languages
English (en)
Other versions
DE68909245D1 (de
Inventor
Roberto Pasqualini
Luciano Magon
Andre Bardy
Adriano Duatti
Andrea Marchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CIS Bio International SA
Original Assignee
CIS Bio International SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8815415A external-priority patent/FR2639542B1/fr
Priority claimed from FR8907731A external-priority patent/FR2648049B1/fr
Application filed by CIS Bio International SA filed Critical CIS Bio International SA
Publication of DE68909245D1 publication Critical patent/DE68909245D1/de
Application granted granted Critical
Publication of DE68909245T2 publication Critical patent/DE68909245T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic System
    • C07F13/005—Compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0476—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from monodendate ligands, e.g. sestamibi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
DE89913235T 1988-11-25 1989-11-24 Übergangsmetall-stickstoffkomplex enthaltendes radiopharmazeutisches produkt mit einer neigung zum herzgewebe. Expired - Fee Related DE68909245T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR8815415A FR2639542B1 (fr) 1988-11-25 1988-11-25 Produit radiopharmaceutique a tropisme cardiaque comportant un complexe nitrido d'un metal de transition, et son procede de preparation
FR8907731A FR2648049B1 (fr) 1989-06-12 1989-06-12 Produit radiopharmaceutique a tropisme cardiaque comportant un complexe nitruro d'un metal de transition, et son procede de preparation
PCT/FR1989/000608 WO1990006137A1 (fr) 1988-11-25 1989-11-24 Produit radiopharmaceutique ayant notamment un tropisme cardiaque comportant un complexe nitruro d'un metal de transition, et son procede de preparation

Publications (2)

Publication Number Publication Date
DE68909245D1 DE68909245D1 (de) 1993-10-21
DE68909245T2 true DE68909245T2 (de) 1994-03-17

Family

ID=26227009

Family Applications (1)

Application Number Title Priority Date Filing Date
DE89913235T Expired - Fee Related DE68909245T2 (de) 1988-11-25 1989-11-24 Übergangsmetall-stickstoffkomplex enthaltendes radiopharmazeutisches produkt mit einer neigung zum herzgewebe.

Country Status (9)

Country Link
US (1) US5288476A (de)
EP (1) EP0445190B1 (de)
JP (1) JP3015970B2 (de)
AU (1) AU623204B2 (de)
CA (1) CA2003880C (de)
DE (1) DE68909245T2 (de)
ES (1) ES2059831T3 (de)
RU (1) RU2049789C1 (de)
WO (1) WO1990006137A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2664166A1 (fr) * 1990-07-04 1992-01-10 Cis Bio Int Procede de preparation de complexes nitruro de metaux de transition utilisables comme produits radiopharmaceutiques ou pour la synthese de nouveaux produits radiopharmaceutiques.
AU9172191A (en) * 1990-12-12 1992-07-08 Mallinckrodt Medical, Inc. Method of radioactive labelling of blood cells and kit therefor
FR2679452B1 (fr) * 1991-07-22 1993-11-12 Cis Bio International Produit radiopharmaceutique ayant notamment un tropisme cerebral, comportant un complexe nitruro d'un metal de transition, et son procede de preparation.
FR2698272B1 (fr) * 1992-11-20 1994-12-30 Cis Bio Int Procédé de marquage cellulaire au moyen de complexes nitruro-bis (dithiocarbamato)Tc-99m et trousse pour la mise en Óoeuvre de ce procédé.
US6331273B1 (en) 1995-04-25 2001-12-18 Discovery Partners International Remotely programmable matrices with memories
US6329139B1 (en) 1995-04-25 2001-12-11 Discovery Partners International Automated sorting system for matrices with memory
US5874214A (en) 1995-04-25 1999-02-23 Irori Remotely programmable matrices with memories
US6416714B1 (en) 1995-04-25 2002-07-09 Discovery Partners International, Inc. Remotely programmable matrices with memories
US5751629A (en) 1995-04-25 1998-05-12 Irori Remotely programmable matrices with memories
US6017496A (en) 1995-06-07 2000-01-25 Irori Matrices with memories and uses thereof
FR2736834B1 (fr) * 1995-07-17 1997-08-29 Cis Bio Int Produits radiopharmaceutiques a tropisme cardiaque comportant un complexe nitruro d'un metal de transition et ayant une clairance myocardique rapide
JP4338394B2 (ja) * 2000-07-28 2009-10-07 日本メジフィジックス株式会社 テクネチウム−９９ｍ窒化物ヘテロ錯体を含有する放射性画像診断剤
ES2369027T3 (es) 2006-01-20 2011-11-24 Nihon Medi-Physics Co., Ltd. Compuesto intermedio de un complejo de nitruro de tecnecio para la formación de imágenes radiodiagnósticas.
MD3995C2 (ro) * 2009-05-11 2010-07-31 Государственный Университет Молд0 Utilizare a di(µ-Ofenoxi)-di{[2-(4-aminobenzensulfamido)-5-etil-1,3,4-tiadiazol]-3,5-dibromosalicilidentiosemicarbazonato(-1)-cupru} în calitate de inhibitor al proliferării celulelor T-47D ale cancerului mamar

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5361234A (en) * 1976-11-12 1978-06-01 Matsushita Electric Ind Co Ltd Memory unit
US4247534A (en) * 1978-07-31 1981-01-27 The Procter & Gamble Company Radiographic scanning agent
JPS55160382A (en) * 1979-05-31 1980-12-13 Toshiba Corp Memory unit
JPS5786959A (en) * 1980-11-19 1982-05-31 Matsushita Electric Ind Co Ltd Data transfer control system
JPS6059461A (ja) * 1983-09-13 1985-04-05 Matsushita Electric Ind Co Ltd プログラムメモリ装置
JPS61501087A (ja) * 1983-12-29 1986-05-29 オ−ストラリア国 テクネチウム−９９ｍ−標識放射医薬の製造
US4925925A (en) * 1988-06-15 1990-05-15 University Of Cincinnati Radioactive rhenium ligated to 2-hydroxy isobutyric acid and method of use

Also Published As

Publication number Publication date
EP0445190B1 (de) 1993-09-15
CA2003880A1 (fr) 1990-05-25
AU4639289A (en) 1990-06-26
DE68909245D1 (de) 1993-10-21
US5288476A (en) 1994-02-22
AU623204B2 (en) 1992-05-07
ES2059831T3 (es) 1994-11-16
RU2049789C1 (ru) 1995-12-10
EP0445190A1 (de) 1991-09-11
CA2003880C (fr) 2002-01-08
JPH04506653A (ja) 1992-11-19
JP3015970B2 (ja) 2000-03-06
WO1990006137A1 (fr) 1990-06-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee