FR2698272B1 - Procédé de marquage cellulaire au moyen de complexes nitruro-bis (dithiocarbamato)Tc-99m et trousse pour la mise en Óoeuvre de ce procédé. - Google Patents

Procédé de marquage cellulaire au moyen de complexes nitruro-bis (dithiocarbamato)Tc-99m et trousse pour la mise en Óoeuvre de ce procédé.

Info

Publication number
FR2698272B1
FR2698272B1 FR9213963A FR9213963A FR2698272B1 FR 2698272 B1 FR2698272 B1 FR 2698272B1 FR 9213963 A FR9213963 A FR 9213963A FR 9213963 A FR9213963 A FR 9213963A FR 2698272 B1 FR2698272 B1 FR 2698272B1
Authority
FR
France
Prior art keywords
nitruro
dithiocarbamato
complexes
kit
bis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9213963A
Other languages
English (en)
Other versions
FR2698272A1 (fr
Inventor
Roberto Pasqualini
Annick Moisan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CIS Bio International SA
Original Assignee
CIS Bio International SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CIS Bio International SA filed Critical CIS Bio International SA
Priority to FR9213963A priority Critical patent/FR2698272B1/fr
Publication of FR2698272A1 publication Critical patent/FR2698272A1/fr
Application granted granted Critical
Publication of FR2698272B1 publication Critical patent/FR2698272B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G21NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21HOBTAINING ENERGY FROM RADIOACTIVE SOURCES; APPLICATIONS OF RADIATION FROM RADIOACTIVE SOURCES, NOT OTHERWISE PROVIDED FOR; UTILISING COSMIC RADIATION
    • G21H5/00Applications of radiation from radioactive sources or arrangements therefor, not otherwise provided for 
    • G21H5/02Applications of radiation from radioactive sources or arrangements therefor, not otherwise provided for  as tracers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0474Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0476Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from monodendate ligands, e.g. sestamibi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1203Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules in a form not provided for by groups A61K51/1206 - A61K51/1296, e.g. cells, cell fragments, viruses, virus capsides, ghosts, red blood cells, viral vectors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005Compounds without a metal-carbon linkage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Dispersion Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FR9213963A 1992-11-20 1992-11-20 Procédé de marquage cellulaire au moyen de complexes nitruro-bis (dithiocarbamato)Tc-99m et trousse pour la mise en Óoeuvre de ce procédé. Expired - Fee Related FR2698272B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR9213963A FR2698272B1 (fr) 1992-11-20 1992-11-20 Procédé de marquage cellulaire au moyen de complexes nitruro-bis (dithiocarbamato)Tc-99m et trousse pour la mise en Óoeuvre de ce procédé.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9213963A FR2698272B1 (fr) 1992-11-20 1992-11-20 Procédé de marquage cellulaire au moyen de complexes nitruro-bis (dithiocarbamato)Tc-99m et trousse pour la mise en Óoeuvre de ce procédé.

Publications (2)

Publication Number Publication Date
FR2698272A1 FR2698272A1 (fr) 1994-05-27
FR2698272B1 true FR2698272B1 (fr) 1994-12-30

Family

ID=9435742

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9213963A Expired - Fee Related FR2698272B1 (fr) 1992-11-20 1992-11-20 Procédé de marquage cellulaire au moyen de complexes nitruro-bis (dithiocarbamato)Tc-99m et trousse pour la mise en Óoeuvre de ce procédé.

Country Status (1)

Country Link
FR (1) FR2698272B1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5750088A (en) * 1993-03-30 1998-05-12 The Dupont Merck Pharmaceutical Company Stable hydrazones linked to a peptide moiety as reagents for the preparation of radiopharmaceuticals
FR2736834B1 (fr) * 1995-07-17 1997-08-29 Cis Bio Int Produits radiopharmaceutiques a tropisme cardiaque comportant un complexe nitruro d'un metal de transition et ayant une clairance myocardique rapide
CA2215152A1 (fr) * 1996-01-12 1997-07-17 Redcell Canada, Inc. Ancres de proteines seriques et cellulaires destinees a l'imagerie diagnostique
FR2809401B1 (fr) 2000-05-23 2004-01-02 Cis Bio Int Produits radiopharmaceutiques utiles pour le marquage selectif des lymphocytes et leur preparation
FR2832408B1 (fr) * 2001-11-20 2005-07-15 Schering Ag Complexes de technetium ou de rhenium, produits radiopharmaceutiques les contenant et leur preparation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE68909245T2 (de) * 1988-11-25 1994-03-17 Cis Bio International Saclay Übergangsmetall-stickstoffkomplex enthaltendes radiopharmazeutisches produkt mit einer neigung zum herzgewebe.
WO1992010214A1 (fr) * 1990-12-12 1992-06-25 Mallinckrodt Medical, Inc. Procede de marquage isotopique de cellules du sang et kit pour ce faire

Also Published As

Publication number Publication date
FR2698272A1 (fr) 1994-05-27

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Legal Events

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ST Notification of lapse