FR2832408B1 - Complexes de technetium ou de rhenium, produits radiopharmaceutiques les contenant et leur preparation - Google Patents

Complexes de technetium ou de rhenium, produits radiopharmaceutiques les contenant et leur preparation

Info

Publication number
FR2832408B1
FR2832408B1 FR0114991A FR0114991A FR2832408B1 FR 2832408 B1 FR2832408 B1 FR 2832408B1 FR 0114991 A FR0114991 A FR 0114991A FR 0114991 A FR0114991 A FR 0114991A FR 2832408 B1 FR2832408 B1 FR 2832408B1
Authority
FR
France
Prior art keywords
technetium
rhenium
complexes
preparation
products containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0114991A
Other languages
English (en)
Other versions
FR2832408A1 (fr
Inventor
Franck Mevellec
Roberto Pasqualini
Henri Patin
Alain Roucoux
Nicolas Noiret
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Priority to FR0114991A priority Critical patent/FR2832408B1/fr
Priority to EP02803482A priority patent/EP1453841A1/fr
Priority to AU2002366007A priority patent/AU2002366007A1/en
Priority to US10/496,109 priority patent/US20050008568A1/en
Priority to JP2003545668A priority patent/JP2005509686A/ja
Priority to PCT/IB2002/004681 priority patent/WO2003044031A1/fr
Publication of FR2832408A1 publication Critical patent/FR2832408A1/fr
Application granted granted Critical
Publication of FR2832408B1 publication Critical patent/FR2832408B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6891—Pre-targeting systems involving an antibody for targeting specific cells
    • A61K47/6897—Pre-targeting systems with two or three steps using antibody conjugates; Ligand-antiligand therapies
    • A61K47/6898—Pre-targeting systems with two or three steps using antibody conjugates; Ligand-antiligand therapies using avidin- or biotin-conjugated antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005—Compounds without a metal-carbon linkage

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Optics & Photonics (AREA)
  • Medical Informatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR0114991A 2001-11-20 2001-11-20 Complexes de technetium ou de rhenium, produits radiopharmaceutiques les contenant et leur preparation Expired - Fee Related FR2832408B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR0114991A FR2832408B1 (fr) 2001-11-20 2001-11-20 Complexes de technetium ou de rhenium, produits radiopharmaceutiques les contenant et leur preparation
EP02803482A EP1453841A1 (fr) 2001-11-20 2002-11-05 Complexes de technetium ou de rhenium, produits radiopharmaceutiques les contenant
AU2002366007A AU2002366007A1 (en) 2001-11-20 2002-11-05 Technetium or rhenium complexes, radiopharmaceutical products comprising them
US10/496,109 US20050008568A1 (en) 2001-11-20 2002-11-05 Technetium or rhenium complexes, radiopharmaceutical products comprising them
JP2003545668A JP2005509686A (ja) 2001-11-20 2002-11-05 テクネチウム及びレニウム錯体類、それらを含んで成る放射性医薬製品
PCT/IB2002/004681 WO2003044031A1 (fr) 2001-11-20 2002-11-05 Complexes de technetium ou de rhenium, produits radiopharmaceutiques les contenant

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0114991A FR2832408B1 (fr) 2001-11-20 2001-11-20 Complexes de technetium ou de rhenium, produits radiopharmaceutiques les contenant et leur preparation

Publications (2)

Publication Number Publication Date
FR2832408A1 FR2832408A1 (fr) 2003-05-23
FR2832408B1 true FR2832408B1 (fr) 2005-07-15

Family

ID=8869579

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0114991A Expired - Fee Related FR2832408B1 (fr) 2001-11-20 2001-11-20 Complexes de technetium ou de rhenium, produits radiopharmaceutiques les contenant et leur preparation

Country Status (6)

Country Link
US (1) US20050008568A1 (fr)
EP (1) EP1453841A1 (fr)
JP (1) JP2005509686A (fr)
AU (1) AU2002366007A1 (fr)
FR (1) FR2832408B1 (fr)
WO (1) WO2003044031A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7708961B2 (en) * 2007-03-31 2010-05-04 Advanced Applied Physics Solutions, Inc. Method and apparatus for isolating the radioisotope 186Rhenium
US9587292B2 (en) * 2009-10-01 2017-03-07 Advanced Applied Physics Solutions, Inc. Method and apparatus for isolating the radioisotope molybdenum-99

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2698272B1 (fr) * 1992-11-20 1994-12-30 Cis Bio Int Procédé de marquage cellulaire au moyen de complexes nitruro-bis (dithiocarbamato)Tc-99m et trousse pour la mise en Óoeuvre de ce procédé.
FR2809401B1 (fr) * 2000-05-23 2004-01-02 Cis Bio Int Produits radiopharmaceutiques utiles pour le marquage selectif des lymphocytes et leur preparation

Also Published As

Publication number Publication date
FR2832408A1 (fr) 2003-05-23
US20050008568A1 (en) 2005-01-13
WO2003044031A1 (fr) 2003-05-30
JP2005509686A (ja) 2005-04-14
AU2002366007A1 (en) 2003-06-10
EP1453841A1 (fr) 2004-09-08

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20070731