FR2648049B1 - Produit radiopharmaceutique a tropisme cardiaque comportant un complexe nitruro d'un metal de transition, et son procede de preparation - Google Patents

Produit radiopharmaceutique a tropisme cardiaque comportant un complexe nitruro d'un metal de transition, et son procede de preparation

Info

Publication number
FR2648049B1
FR2648049B1 FR8907731A FR8907731A FR2648049B1 FR 2648049 B1 FR2648049 B1 FR 2648049B1 FR 8907731 A FR8907731 A FR 8907731A FR 8907731 A FR8907731 A FR 8907731A FR 2648049 B1 FR2648049 B1 FR 2648049B1
Authority
FR
France
Prior art keywords
preparation
transitional metal
radiopharmaceutical product
cardiac tropism
nitruro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR8907731A
Other languages
English (en)
Other versions
FR2648049A1 (fr
Inventor
Pasqualini Roberto
Bardy Andre
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CIS Bio International SA
Original Assignee
CIS Bio International SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR8907731A priority Critical patent/FR2648049B1/fr
Application filed by CIS Bio International SA filed Critical CIS Bio International SA
Priority to DE89913235T priority patent/DE68909245T2/de
Priority to EP89913235A priority patent/EP0445190B1/fr
Priority to AU46392/89A priority patent/AU623204B2/en
Priority to ES89913235T priority patent/ES2059831T3/es
Priority to PCT/FR1989/000608 priority patent/WO1990006137A1/fr
Priority to SU894895504A priority patent/RU2049789C1/ru
Priority to JP2500214A priority patent/JP3015970B2/ja
Priority to AT89913235T priority patent/ATE94412T1/de
Priority to US07/675,938 priority patent/US5288476A/en
Priority to CA002003880A priority patent/CA2003880C/fr
Publication of FR2648049A1 publication Critical patent/FR2648049A1/fr
Application granted granted Critical
Publication of FR2648049B1 publication Critical patent/FR2648049B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005—Compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0476—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from monodendate ligands, e.g. sestamibi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FR8907731A 1988-11-25 1989-06-12 Produit radiopharmaceutique a tropisme cardiaque comportant un complexe nitruro d'un metal de transition, et son procede de preparation Expired - Fee Related FR2648049B1 (fr)

Priority Applications (11)

Application Number Priority Date Filing Date Title
FR8907731A FR2648049B1 (fr) 1989-06-12 1989-06-12 Produit radiopharmaceutique a tropisme cardiaque comportant un complexe nitruro d'un metal de transition, et son procede de preparation
AT89913235T ATE94412T1 (de) 1988-11-25 1989-11-24 Uebergangsmetall-stickstoffkomplex enthaltendes radiopharmazeutisches produkt mit einer neigung zum herzgewebe.
AU46392/89A AU623204B2 (en) 1988-11-25 1989-11-24 Pharmaceutical product having, in particular, a cardiac tropism comprising a nitruro complex of a transition metal and process for preparation thereof
ES89913235T ES2059831T3 (es) 1988-11-25 1989-11-24 Producto radiofarmaceutico que tiene principalmente un tropismo cardiaco que comprende un complejo nitruro de un metal de transicion, y su procedimiento de preparacion.
PCT/FR1989/000608 WO1990006137A1 (fr) 1988-11-25 1989-11-24 Produit radiopharmaceutique ayant notamment un tropisme cardiaque comportant un complexe nitruro d'un metal de transition, et son procede de preparation
SU894895504A RU2049789C1 (ru) 1988-11-25 1989-11-24 Нитридный комплекс переходного металла
DE89913235T DE68909245T2 (de) 1988-11-25 1989-11-24 Übergangsmetall-stickstoffkomplex enthaltendes radiopharmazeutisches produkt mit einer neigung zum herzgewebe.
EP89913235A EP0445190B1 (fr) 1988-11-25 1989-11-24 Produit radiopharmaceutique ayant notamment un tropisme cardiaque comportant un complexe nitruro d'un metal de transition, et son procede de preparation
US07/675,938 US5288476A (en) 1988-11-25 1989-11-24 Radiopharmaceutical product more particularly having a cardiac tropism incorporating a nitride complex of a transition metal and its preparation process
CA002003880A CA2003880C (fr) 1988-11-25 1989-11-24 Produit radiopharmaceutique ayant notamment un tropisme cardiaque comportant un complexe nitruro d'un metal de transition, et son procede de preparation
JP2500214A JP3015970B2 (ja) 1988-11-25 1989-11-24 遷移金属の窒化物錯体を含んでいる、心臓への向性を特に有する放射性医薬製品およびその製造方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8907731A FR2648049B1 (fr) 1989-06-12 1989-06-12 Produit radiopharmaceutique a tropisme cardiaque comportant un complexe nitruro d'un metal de transition, et son procede de preparation

Publications (2)

Publication Number Publication Date
FR2648049A1 FR2648049A1 (fr) 1990-12-14
FR2648049B1 true FR2648049B1 (fr) 1994-10-21

Family

ID=9382611

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8907731A Expired - Fee Related FR2648049B1 (fr) 1988-11-25 1989-06-12 Produit radiopharmaceutique a tropisme cardiaque comportant un complexe nitruro d'un metal de transition, et son procede de preparation

Country Status (1)

Country Link
FR (1) FR2648049B1 (fr)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3484511D1 (de) * 1983-12-29 1991-05-29 Commw Of Australia Herstellung von mit 99m tc markierten radioarzneimitteln.

Also Published As

Publication number Publication date
FR2648049A1 (fr) 1990-12-14

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Legal Events

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ST Notification of lapse