DE60323981D1 - Zimtsäureamidderivate - Google Patents

Zimtsäureamidderivate

Info

Publication number
DE60323981D1
DE60323981D1 DE60323981T DE60323981T DE60323981D1 DE 60323981 D1 DE60323981 D1 DE 60323981D1 DE 60323981 T DE60323981 T DE 60323981T DE 60323981 T DE60323981 T DE 60323981T DE 60323981 D1 DE60323981 D1 DE 60323981D1
Authority
DE
Germany
Prior art keywords
zimtsäureamidderivate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60323981T
Other languages
English (en)
Inventor
Synese Jolidon
Sarmiento Rosa Maria Rodriguez
Andrew William Thomas
Wolfgang Wostl
Rene Wyler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of DE60323981D1 publication Critical patent/DE60323981D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
DE60323981T 2002-07-15 2003-07-07 Zimtsäureamidderivate Expired - Fee Related DE60323981D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02015583 2002-07-15
PCT/EP2003/007231 WO2004007429A1 (en) 2002-07-15 2003-07-07 Cinnamide derivatives

Publications (1)

Publication Number Publication Date
DE60323981D1 true DE60323981D1 (de) 2008-11-20

Family

ID=30011071

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60323981T Expired - Fee Related DE60323981D1 (de) 2002-07-15 2003-07-07 Zimtsäureamidderivate

Country Status (20)

Country Link
US (1) US6900354B2 (de)
EP (1) EP1523469B1 (de)
JP (1) JP4108679B2 (de)
KR (1) KR20050029206A (de)
CN (1) CN1305838C (de)
AR (1) AR040489A1 (de)
AT (1) ATE410407T1 (de)
AU (1) AU2003281030B2 (de)
BR (1) BR0312658A (de)
CA (1) CA2493372A1 (de)
DE (1) DE60323981D1 (de)
ES (1) ES2314219T3 (de)
MX (1) MXPA05000583A (de)
PA (1) PA8577201A1 (de)
PE (1) PE20040667A1 (de)
PL (1) PL373390A1 (de)
RU (1) RU2318802C2 (de)
TW (1) TW200404760A (de)
UY (1) UY27894A1 (de)
WO (1) WO2004007429A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1588704A1 (de) * 2004-04-22 2005-10-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamidderivate zur Behandlung des Restless-Leg-Syndroms und der Suchterkrankungen
KR101128065B1 (ko) 2004-05-26 2012-04-12 에자이 알앤드디 매니지먼트 가부시키가이샤 신나미드 화합물
AU2005297966B2 (en) * 2004-10-26 2010-12-23 Eisai R & D Management Co., Ltd. Amorphous object of cinnamide compound
UA90708C2 (ru) 2005-02-25 2010-05-25 Ф. Хоффманн-Ля Рош Аг Таблетки с улучшенной дисперсностью лекарственного вещества
WO2006127133A2 (en) 2005-04-01 2006-11-30 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
WO2007008963A1 (en) * 2005-07-13 2007-01-18 Jenrin Discovery Mao-b inhibitors useful for treating obesity
PL209602B1 (pl) 2005-10-20 2011-09-30 Inst Chemii Bioorg Pan Sposób otrzymywania amidu kwasu 3-(4-hydroksyfenylo)propanowego
WO2007058305A1 (ja) * 2005-11-18 2007-05-24 Eisai R & D Management Co., Ltd. シンナミド誘導体の製造方法
WO2007058304A1 (ja) * 2005-11-18 2007-05-24 Eisai R & D Management Co., Ltd. シンナミド化合物の塩またはそれらの溶媒和物
TWI370130B (en) * 2005-11-24 2012-08-11 Eisai R&D Man Co Ltd Two cyclic cinnamide compound
CN101312965B (zh) * 2005-11-24 2011-07-20 卫材R&D管理有限公司 吗啉型肉桂酰胺化合物
NZ568050A (en) 2005-11-24 2010-09-30 Eisai R&D Man Co Ltd Morpholine type cinnamide compound
TWI378091B (en) 2006-03-09 2012-12-01 Eisai R&D Man Co Ltd Multi-cyclic cinnamide derivatives
SA07280403B1 (ar) * 2006-07-28 2010-12-01 إيساي أر أند دي منجمنت كو. ليمتد ملح رباعي لمركب سيناميد
TW200848054A (en) * 2007-02-28 2008-12-16 Eisai R&D Man Co Ltd Two cyclic oxomorpholine derivatives
JPWO2008140111A1 (ja) * 2007-05-16 2010-08-05 エーザイ・アール・アンド・ディー・マネジメント株式会社 シンナミド誘導体のワンポット製造方法
US7986144B2 (en) * 2007-07-26 2011-07-26 Schlumberger Technology Corporation Sensor and insulation layer structure for well logging instruments
US7935815B2 (en) * 2007-08-31 2011-05-03 Eisai R&D Management Co., Ltd. Imidazoyl pyridine compounds and salts thereof
MX2010002098A (es) 2007-08-31 2010-03-30 Eisai R&D Man Co Ltd Compuesto policiclico.
CA2712095A1 (en) * 2008-01-28 2009-08-06 Eisai R&D Management Co., Ltd. Crystalline cinnamide compounds or salts thereof
NL2005655A (en) 2009-12-09 2011-06-14 Asml Netherlands Bv A lithographic apparatus and a device manufacturing method.
CN104030941B (zh) * 2014-06-23 2016-04-27 常州大学 一种3-（4-羟基苯基）丙酰胺的合成方法
CN107011313B (zh) * 2016-01-27 2021-11-30 天士力医药集团股份有限公司 取代桂皮酰胺衍生物在制备抗焦虑药物中的应用
US11173136B2 (en) 2018-01-10 2021-11-16 Brightseed, Inc. Method for modulating metabolism

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2645019A1 (de) * 1989-03-30 1990-10-05 Fournier Innovation Synergie
US5679715A (en) 1995-06-07 1997-10-21 Harris; Richard Y. Method for treating multiple sclerosis
WO1997033572A1 (en) 1996-03-15 1997-09-18 Somerset Pharmaceuticals, Inc. Method for preventing and treating peripheral neurophathy by administering selegiline
WO2001034172A2 (en) 1999-11-05 2001-05-17 Vela Pharmaceuticals Inc. Methods and compositions for treating reward deficiency syndrome

Also Published As

Publication number Publication date
CA2493372A1 (en) 2004-01-22
BR0312658A (pt) 2005-04-26
RU2005104104A (ru) 2005-10-10
KR20050029206A (ko) 2005-03-24
CN1305838C (zh) 2007-03-21
PE20040667A1 (es) 2004-09-25
WO2004007429A1 (en) 2004-01-22
AR040489A1 (es) 2005-04-06
UY27894A1 (es) 2003-12-31
RU2318802C2 (ru) 2008-03-10
EP1523469B1 (de) 2008-10-08
PA8577201A1 (es) 2004-02-07
JP4108679B2 (ja) 2008-06-25
US20040034096A1 (en) 2004-02-19
TW200404760A (en) 2004-04-01
JP2005533092A (ja) 2005-11-04
PL373390A1 (en) 2005-08-22
AU2003281030B2 (en) 2009-05-28
US6900354B2 (en) 2005-05-31
ATE410407T1 (de) 2008-10-15
EP1523469A1 (de) 2005-04-20
CN1665774A (zh) 2005-09-07
ES2314219T3 (es) 2009-03-16
MXPA05000583A (es) 2005-04-19
AU2003281030A1 (en) 2004-02-02

Similar Documents

Publication Publication Date Title
ATE457980T1 (de) Aryloxime
ATE534648T1 (de) C-6-modifizierte indazolylpyrrolotriazine
DE50305852D1 (de) Einspritzventil
DE50306589D1 (de) Wischblatt
NO20043728L (no) Astaksantinestere
ATE318817T1 (de) Aza-arylpiperazine
ATE427876T1 (de) Luftkissenboot
DE50212360D1 (de) Anfahrhilfesteuerungsvorrichtung
DE50212349D1 (de) Hirurgie
DE50301200D1 (de) Wischblatt
DE60323981D1 (de) Zimtsäureamidderivate
ATE349458T1 (de) Etonogestrelester
DE50305301D1 (de) Einspritzventil
ATA1572002A (de) Managementspleisskassette
DE50307971D1 (de) Gelenklager
DE50301960D1 (de) Hydrolager
DE50301464D1 (de) Schraubensicherung
DE50309499D1 (de) Librierwerkzeugen
DE50302660D1 (de) Stopfmachine
ATA4142004A (de) Trägerverbau
DE50305973D1 (de) Auffangwanne
ATE469773T1 (de) Zugöse
DE50307628D1 (de) Getraenkehalter
DE50303317D1 (de) Einschub-leistungsschalter
ATA19152002A (de) Hubkupplung

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee