BR0312658A - Derivados de cinamida - Google Patents
Derivados de cinamidaInfo
- Publication number
- BR0312658A BR0312658A BR0312658-7A BR0312658A BR0312658A BR 0312658 A BR0312658 A BR 0312658A BR 0312658 A BR0312658 A BR 0312658A BR 0312658 A BR0312658 A BR 0312658A
- Authority
- BR
- Brazil
- Prior art keywords
- derivatives
- cinamide
- phenyl
- propinamido
- mao
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
"DERIVADOS DE CINAMIDA". A presente invenção refere-se a derivados de 3-fenil-propionamido, 3-fenil-acrilamido e 3-fenil-propinamido, processos para sua preparação, composições contendo os mesmos e os usos dos referidos derivados como inibidores da MAO-B.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02015583 | 2002-07-15 | ||
PCT/EP2003/007231 WO2004007429A1 (en) | 2002-07-15 | 2003-07-07 | Cinnamide derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0312658A true BR0312658A (pt) | 2005-04-26 |
Family
ID=30011071
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0312658-7A BR0312658A (pt) | 2002-07-15 | 2003-07-07 | Derivados de cinamida |
Country Status (20)
Country | Link |
---|---|
US (1) | US6900354B2 (pt) |
EP (1) | EP1523469B1 (pt) |
JP (1) | JP4108679B2 (pt) |
KR (1) | KR20050029206A (pt) |
CN (1) | CN1305838C (pt) |
AR (1) | AR040489A1 (pt) |
AT (1) | ATE410407T1 (pt) |
AU (1) | AU2003281030B2 (pt) |
BR (1) | BR0312658A (pt) |
CA (1) | CA2493372A1 (pt) |
DE (1) | DE60323981D1 (pt) |
ES (1) | ES2314219T3 (pt) |
MX (1) | MXPA05000583A (pt) |
PA (1) | PA8577201A1 (pt) |
PE (1) | PE20040667A1 (pt) |
PL (1) | PL373390A1 (pt) |
RU (1) | RU2318802C2 (pt) |
TW (1) | TW200404760A (pt) |
UY (1) | UY27894A1 (pt) |
WO (1) | WO2004007429A1 (pt) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1588704A1 (en) | 2004-04-22 | 2005-10-26 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders |
TWI335816B (en) | 2004-05-26 | 2011-01-11 | Eisai R&D Man Co Ltd | Cinnamide compound |
ATE458729T1 (de) * | 2004-10-26 | 2010-03-15 | Eisai R&D Man Co Ltd | Amorphe form einer zimtsäureamidverbindung |
EP2281556A1 (en) | 2005-02-25 | 2011-02-09 | F. Hoffmann-La Roche AG | Tablets with improved drugs substance dispersibility |
US8022249B2 (en) | 2005-04-01 | 2011-09-20 | Wellstat Therapeutics Corporation | Compounds for the treatment of metabolic disorders |
US8138209B2 (en) * | 2005-07-13 | 2012-03-20 | Jenrin Discovery, Inc. | Substituted picolinamides as MAO-B inhibitors useful for treating obesity |
PL209602B1 (pl) | 2005-10-20 | 2011-09-30 | Inst Chemii Bioorg Pan | Sposób otrzymywania amidu kwasu 3-(4-hydroksyfenylo)propanowego |
AU2006316005A1 (en) * | 2005-11-18 | 2007-05-24 | Eisai R & D Management Co., Ltd. | Process for production of cinnamamide derivative |
US20090048448A1 (en) * | 2005-11-18 | 2009-02-19 | Ikuo Kushida | Salts of cynnamide compound or solvates thereof |
MY144960A (en) | 2005-11-24 | 2011-11-30 | Eisai R&D Man Co Ltd | Morpholine type cinnamide compound |
TWI370130B (en) * | 2005-11-24 | 2012-08-11 | Eisai R&D Man Co Ltd | Two cyclic cinnamide compound |
ZA200803939B (en) * | 2005-11-24 | 2009-10-28 | Eisai R&D Man Co Ltd | Morpholine type cinnamide compound |
TWI378091B (en) * | 2006-03-09 | 2012-12-01 | Eisai R&D Man Co Ltd | Multi-cyclic cinnamide derivatives |
AR062095A1 (es) * | 2006-07-28 | 2008-10-15 | Eisai R&D Man Co Ltd | Profarmaco de compuesto cinamida |
PE20081791A1 (es) * | 2007-02-28 | 2009-02-07 | Eisai Randd Man Co Ltd | Dos derivados ciclicos de oxomorfolina |
CA2687262A1 (en) * | 2007-05-16 | 2008-11-20 | Naoyuki Shimomura | One-pot production process for cinnamide derivative |
US7986144B2 (en) * | 2007-07-26 | 2011-07-26 | Schlumberger Technology Corporation | Sensor and insulation layer structure for well logging instruments |
US7935815B2 (en) * | 2007-08-31 | 2011-05-03 | Eisai R&D Management Co., Ltd. | Imidazoyl pyridine compounds and salts thereof |
US9453000B2 (en) | 2007-08-31 | 2016-09-27 | Eisai R&D Management Co., Ltd. | Polycyclic compound |
JPWO2009096349A1 (ja) * | 2008-01-28 | 2011-05-26 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 結晶性のシンナミド化合物またはその塩 |
NL2005655A (en) | 2009-12-09 | 2011-06-14 | Asml Netherlands Bv | A lithographic apparatus and a device manufacturing method. |
CN104030941B (zh) * | 2014-06-23 | 2016-04-27 | 常州大学 | 一种3-(4-羟基苯基)丙酰胺的合成方法 |
CN107011313B (zh) * | 2016-01-27 | 2021-11-30 | 天士力医药集团股份有限公司 | 取代桂皮酰胺衍生物在制备抗焦虑药物中的应用 |
MX2020007394A (es) | 2018-01-10 | 2020-09-03 | Brightseed Inc | Metodo para modular el metabolismo. |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2645019A1 (pt) * | 1989-03-30 | 1990-10-05 | Fournier Innovation Synergie | |
US5679715A (en) | 1995-06-07 | 1997-10-21 | Harris; Richard Y. | Method for treating multiple sclerosis |
US6239181B1 (en) | 1996-03-15 | 2001-05-29 | Somerset Pharmaceuticals, Inc. | Method for preventing and treating peripheral neurophathy by administering selegiline |
WO2001034172A2 (en) | 1999-11-05 | 2001-05-17 | Vela Pharmaceuticals Inc. | Methods and compositions for treating reward deficiency syndrome |
-
2003
- 2003-07-03 US US10/613,785 patent/US6900354B2/en not_active Expired - Fee Related
- 2003-07-07 BR BR0312658-7A patent/BR0312658A/pt not_active IP Right Cessation
- 2003-07-07 MX MXPA05000583A patent/MXPA05000583A/es active IP Right Grant
- 2003-07-07 CA CA002493372A patent/CA2493372A1/en not_active Abandoned
- 2003-07-07 DE DE60323981T patent/DE60323981D1/de not_active Expired - Fee Related
- 2003-07-07 PL PL03373390A patent/PL373390A1/xx unknown
- 2003-07-07 EP EP03740425A patent/EP1523469B1/en not_active Expired - Lifetime
- 2003-07-07 WO PCT/EP2003/007231 patent/WO2004007429A1/en active Application Filing
- 2003-07-07 KR KR1020057000637A patent/KR20050029206A/ko not_active Application Discontinuation
- 2003-07-07 AU AU2003281030A patent/AU2003281030B2/en not_active Ceased
- 2003-07-07 CN CNB038160579A patent/CN1305838C/zh not_active Expired - Fee Related
- 2003-07-07 JP JP2004520497A patent/JP4108679B2/ja not_active Expired - Fee Related
- 2003-07-07 ES ES03740425T patent/ES2314219T3/es not_active Expired - Lifetime
- 2003-07-07 RU RU2005104104/04A patent/RU2318802C2/ru not_active IP Right Cessation
- 2003-07-07 AT AT03740425T patent/ATE410407T1/de not_active IP Right Cessation
- 2003-07-10 PA PA20038577201A patent/PA8577201A1/es unknown
- 2003-07-11 AR AR20030102502A patent/AR040489A1/es not_active Application Discontinuation
- 2003-07-14 UY UY27894A patent/UY27894A1/es not_active Application Discontinuation
- 2003-07-15 PE PE2003000706A patent/PE20040667A1/es not_active Application Discontinuation
- 2003-07-15 TW TW092119275A patent/TW200404760A/zh unknown
Also Published As
Publication number | Publication date |
---|---|
EP1523469A1 (en) | 2005-04-20 |
CN1305838C (zh) | 2007-03-21 |
US6900354B2 (en) | 2005-05-31 |
ATE410407T1 (de) | 2008-10-15 |
EP1523469B1 (en) | 2008-10-08 |
CA2493372A1 (en) | 2004-01-22 |
PE20040667A1 (es) | 2004-09-25 |
RU2318802C2 (ru) | 2008-03-10 |
PA8577201A1 (es) | 2004-02-07 |
US20040034096A1 (en) | 2004-02-19 |
CN1665774A (zh) | 2005-09-07 |
KR20050029206A (ko) | 2005-03-24 |
RU2005104104A (ru) | 2005-10-10 |
DE60323981D1 (de) | 2008-11-20 |
JP4108679B2 (ja) | 2008-06-25 |
PL373390A1 (en) | 2005-08-22 |
TW200404760A (en) | 2004-04-01 |
ES2314219T3 (es) | 2009-03-16 |
JP2005533092A (ja) | 2005-11-04 |
WO2004007429A1 (en) | 2004-01-22 |
AU2003281030A1 (en) | 2004-02-02 |
UY27894A1 (es) | 2003-12-31 |
AR040489A1 (es) | 2005-04-06 |
AU2003281030B2 (en) | 2009-05-28 |
MXPA05000583A (es) | 2005-04-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 8A E 9A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2157 DE 08/05/2012. |