DE60323468D1 - Vögelzell-linien und deren verwendung zur herstellung interessanter biologischer substanzen - Google Patents
Vögelzell-linien und deren verwendung zur herstellung interessanter biologischer substanzenInfo
- Publication number
- DE60323468D1 DE60323468D1 DE60323468T DE60323468T DE60323468D1 DE 60323468 D1 DE60323468 D1 DE 60323468D1 DE 60323468 T DE60323468 T DE 60323468T DE 60323468 T DE60323468 T DE 60323468T DE 60323468 D1 DE60323468 D1 DE 60323468D1
- Authority
- DE
- Germany
- Prior art keywords
- cell lines
- serum
- growth factors
- medium
- feeder layer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000126 substance Substances 0.000 title 1
- 239000003102 growth factor Substances 0.000 abstract 4
- 210000002966 serum Anatomy 0.000 abstract 4
- 241000271566 Aves Species 0.000 abstract 3
- 239000002609 medium Substances 0.000 abstract 3
- 239000007640 basal medium Substances 0.000 abstract 2
- 230000001464 adherent effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000000750 progressive effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
- C12N2500/92—Medium free of human- or animal-derived components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
- C12N2500/95—Protein-free medium and culture conditions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Chemical & Material Sciences (AREA)
- Gynecology & Obstetrics (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Reproductive Health (AREA)
- Developmental Biology & Embryology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Feeding And Watering For Cattle Raising And Animal Husbandry (AREA)
- Farming Of Fish And Shellfish (AREA)
- Peptides Or Proteins (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0202945A FR2836924B1 (fr) | 2002-03-08 | 2002-03-08 | Lignees de cellules aviaires utiles pour la production de substances d'interet |
| PCT/FR2003/000735 WO2003076601A1 (fr) | 2002-03-08 | 2003-03-07 | Lignées de cellules aviaires utiles pour la production de substances d'intérêt |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60323468D1 true DE60323468D1 (de) | 2008-10-23 |
Family
ID=27763651
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60323468T Expired - Lifetime DE60323468D1 (de) | 2002-03-08 | 2003-03-07 | Vögelzell-linien und deren verwendung zur herstellung interessanter biologischer substanzen |
Country Status (14)
| Country | Link |
|---|---|
| US (4) | US20040058441A1 (enExample) |
| EP (2) | EP1992687B1 (enExample) |
| JP (2) | JP5025888B2 (enExample) |
| CN (2) | CN100562567C (enExample) |
| AT (1) | ATE408004T1 (enExample) |
| AU (1) | AU2003227820B2 (enExample) |
| CA (1) | CA2478125C (enExample) |
| DE (1) | DE60323468D1 (enExample) |
| DK (1) | DK1483369T3 (enExample) |
| ES (1) | ES2312775T3 (enExample) |
| FR (1) | FR2836924B1 (enExample) |
| PT (1) | PT1483369E (enExample) |
| SI (1) | SI1483369T1 (enExample) |
| WO (1) | WO2003076601A1 (enExample) |
Families Citing this family (121)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7445924B2 (en) * | 2000-11-23 | 2008-11-04 | Bavarian Nordic A/S | Modified Vaccinia Ankara virus variant and cultivation method |
| US20060191026A1 (en) | 2005-02-18 | 2006-08-24 | Origen Therapeutics, Inc. | Tissue specific expression of antibodies in chickens |
| US7145057B2 (en) | 2002-02-01 | 2006-12-05 | Origen Therapeutics, Inc. | Chimeric bird from embryonic stem cells |
| FR2836924B1 (fr) | 2002-03-08 | 2005-01-14 | Vivalis | Lignees de cellules aviaires utiles pour la production de substances d'interet |
| AU2003264144C1 (en) * | 2002-09-05 | 2009-12-17 | Bavarian Nordic A/S | Method for the cultivation of primary cells and for the amplification of viruses under serum free conditions |
| AU2003296974A1 (en) * | 2002-12-13 | 2004-07-14 | Aventis Pasteur, Inc. | Production of alvac on avian embryonic stem cells |
| EP1500699A1 (en) * | 2003-07-22 | 2005-01-26 | Vivalis | Production of vaccinia virus with adherent or non adherent avian cell lines |
| KR101121971B1 (ko) | 2003-07-22 | 2012-03-09 | 비바리스 | 부착성 또는 비부착성 조류 세포주를 이용한폭스바이러스의 생산 |
| EP1678292A4 (en) * | 2003-09-18 | 2008-05-07 | Univ Emory | IMPROVED MVA VACCINES |
| US20090104226A1 (en) | 2004-05-21 | 2009-04-23 | Novartis Vaccines And Diagnostics Inc. | Alphavirus Vectors for Respiratory Pathogen Vaccines |
| RS51665B (sr) | 2004-09-09 | 2011-10-31 | Novartis Vaccines And Diagnostics Gmbh. | Smanjenje potencijalnih jatrogenih rizika povezanih sa vakcinama protiv gripa |
| AU2005314563B2 (en) | 2004-11-03 | 2011-06-30 | Seqirus UK Limited | Influenza vaccination |
| FR2878860A1 (fr) * | 2004-12-08 | 2006-06-09 | Vivalis Sa | Lignees de cellules souches humaines derivees de cellules es et utilisations pour la production de vaccins et de proteines recombinantes |
| AU2011253998B2 (en) * | 2005-04-11 | 2014-04-24 | Valneva | Process of manufacturing viral vaccines in suspension avian embryonic derived stem cell lines |
| FR2884255B1 (fr) * | 2005-04-11 | 2010-11-05 | Vivalis | Utilisation de lignees de cellules souches aviaires ebx pour la production de vaccin contre la grippe |
| ATE494906T1 (de) | 2005-11-01 | 2011-01-15 | Novartis Vaccines & Diagnostic | Von zellen stammende virale impfstoffe mit geringen mengen an rest-zell-dna |
| WO2007052055A1 (en) | 2005-11-04 | 2007-05-10 | Novartis Vaccines And Diagnostics Srl | Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture |
| CA2628424A1 (en) | 2005-11-04 | 2007-05-10 | Novartis Vaccines And Diagnostics S.R.L. | Adjuvanted influenza vaccines including cytokine-inducing agents |
| KR20080069232A (ko) | 2005-11-04 | 2008-07-25 | 노바티스 백신즈 앤드 다이아그노스틱스 에스.알.엘. | 스플리트 인플루엔자 백신에 대한 보조제로서 유리 수성상계면활성제를 갖는 에멀젼 |
| NZ594482A (en) | 2005-11-04 | 2012-11-30 | Novartis Vaccines & Diagnostic | Influenza vaccines with reduced amount of oil-in-water emulsion as adjuvant |
| ES2377884T3 (es) | 2005-11-04 | 2012-04-02 | Novartis Vaccines And Diagnostics S.R.L. | Vacunas contra la gripe que incluyen combinaciones de adyuvantes particulados e inmunopotenciadores |
| PL2478916T3 (pl) | 2006-01-27 | 2020-11-16 | Seqirus UK Limited | Szczepionki przeciw grypie zawierające hemaglutyninę i białka macierzy |
| FR2898909A1 (fr) | 2006-03-24 | 2007-09-28 | Agronomique Inst Nat Rech | Combinaison de marqueurs de cellules aviaires |
| WO2007110776A1 (en) | 2006-03-24 | 2007-10-04 | Novartis Vaccines And Diagnostics Gmbh & Co Kg | Storage of influenza vaccines without refrigeration |
| GB0614460D0 (en) | 2006-07-20 | 2006-08-30 | Novartis Ag | Vaccines |
| WO2008017704A1 (en) | 2006-08-09 | 2008-02-14 | Vivalis | Method of production of transgenic avian using embryonic stem cells |
| NZ575271A (en) | 2006-09-11 | 2011-09-30 | Novartis Ag | Making influenza virus vaccines without using eggs |
| JP2011506264A (ja) | 2006-12-06 | 2011-03-03 | ノバルティス アーゲー | インフルエンザウイルスの4つの株に由来する抗原を含むワクチン |
| CN100443588C (zh) * | 2006-12-11 | 2008-12-17 | 中国农业科学院北京畜牧兽医研究所 | 静宁鸡胚成纤维细胞系及其培养方法 |
| EP1985305A1 (en) | 2007-04-24 | 2008-10-29 | Vivalis | Duck embryonic derived stem cell lines for the production of viral vaccines |
| EP1995309A1 (en) * | 2007-05-21 | 2008-11-26 | Vivalis | Recombinant protein production in avian EBx® cells |
| PT2185191E (pt) | 2007-06-27 | 2012-11-27 | Novartis Ag | Vacinas contra a gripe com baixo teor de aditivos |
| BRPI0811787B1 (pt) * | 2007-07-03 | 2018-10-09 | Transgene Sa | usos de uma célula imortalizada e processo para imortalizar uma célula aviária |
| US20090028831A1 (en) * | 2007-07-23 | 2009-01-29 | University Of Kentucky Research Foundation | Stem cell regulator, compositions and methods of use |
| GB0810305D0 (en) | 2008-06-05 | 2008-07-09 | Novartis Ag | Influenza vaccination |
| EP2235532B1 (en) | 2007-12-24 | 2013-04-24 | Novartis AG | Assays for adsorbed influenza vaccines |
| US8506966B2 (en) | 2008-02-22 | 2013-08-13 | Novartis Ag | Adjuvanted influenza vaccines for pediatric use |
| KR20140096162A (ko) | 2008-02-25 | 2014-08-04 | 백스터 인터내셔널 인코포레이티드 | 연속 세포주 제조 방법 |
| JP5518041B2 (ja) | 2008-03-18 | 2014-06-11 | ノバルティス アーゲー | インフルエンザウイルスワクチン抗原の調製における改良 |
| US8716016B2 (en) * | 2008-04-23 | 2014-05-06 | Board Of Trustees Of Michigan State University | Immortal avian cell line and methods of use |
| EP2379598B1 (en) | 2009-01-19 | 2015-03-11 | Innate Pharma | Anti-kir3d antibodies |
| JP2012517416A (ja) | 2009-02-10 | 2012-08-02 | ノバルティス アーゲー | 増加した量のh3抗原を含むインフルエンザワクチン |
| WO2010092476A1 (en) | 2009-02-10 | 2010-08-19 | Novartis Ag | Influenza vaccine regimens for pandemic-associated strains |
| EA023662B1 (ru) | 2009-02-10 | 2016-06-30 | Новартис Аг | Вакцины против гриппа со сниженным количеством сквалена |
| DE102010018462A1 (de) | 2009-04-27 | 2011-04-07 | Novartis Ag | Impfstoffe zum Schutz gegen Influenza |
| EP4183412B1 (en) | 2009-07-15 | 2024-08-14 | GlaxoSmithKline Biologicals SA | Rsv f protein compositions and methods for making same |
| CN102695523A (zh) | 2009-09-10 | 2012-09-26 | 诺华有限公司 | 针对呼吸道疾病的组合疫苗 |
| GB0918830D0 (en) | 2009-10-27 | 2009-12-09 | Glaxosmithkline Biolog Niederl | Process |
| GB0919117D0 (en) * | 2009-10-30 | 2009-12-16 | Glaxosmithkline Biolog Sa | Process |
| CA2725435C (en) | 2009-12-15 | 2023-01-03 | University Of Saskatchewan | Vaccines for inclusion body hepatitis |
| WO2011095596A1 (en) | 2010-02-04 | 2011-08-11 | Vivalis | Fed-batch process using concentrated cell culture medium for the efficient production of biologics in eb66 cells |
| FR2956409A1 (fr) | 2010-02-15 | 2011-08-19 | Univ Claude Bernard Lyon | Procedes pour optimiser la production virale par l'inactivation ou l'inhibition du gene hipk2 et cellules modifiees pour la production virale |
| CA2792469A1 (en) | 2010-03-08 | 2011-09-15 | Novartis Ag | Methods of testing for intracellular pathogens |
| US9744228B2 (en) | 2010-04-07 | 2017-08-29 | Norvartis Ag | Method for generating a parvovirus B19 virus-like particle |
| US9441032B2 (en) | 2010-04-07 | 2016-09-13 | Agency For Science, Technology And Research | Binding molecules against Chikungunya virus and uses thereof |
| EP2374816B1 (en) | 2010-04-07 | 2016-09-28 | Agency For Science, Technology And Research | Binding molecules against Chikungunya virus and uses thereof |
| JP6072677B2 (ja) | 2010-05-06 | 2017-02-01 | ノバルティス アーゲー | 微生物の不活化のための有機ペルオキシド化合物 |
| JP5876036B2 (ja) | 2010-05-21 | 2016-03-02 | ノバルティス アーゲー | インフルエンザウイルス再集合方法 |
| CA2801151A1 (en) | 2010-06-01 | 2011-12-08 | Novartis Ag | Concentration of vaccine antigens with lyophilization |
| PL2575872T3 (pl) | 2010-06-01 | 2021-02-22 | Seqirus UK Limited | Zatężanie antygenów szczepionkowych grypy bez liofilizacji |
| CA2804501C (en) | 2010-07-06 | 2021-01-26 | Novartis Ag | Noro virus derived immunogenic compositions and methods |
| GB201011502D0 (en) | 2010-07-08 | 2010-08-25 | Glaxosmithkline Biolog Sa | Novel process |
| CA2808965C (en) | 2010-08-20 | 2020-01-07 | Theraject, Inc. | Soluble needle arrays for delivery of influenza vaccines |
| CA3150342A1 (en) | 2010-09-07 | 2012-03-15 | Technion Research & Development Foundation Limited | Novel methods and culture media for culturing pluripotent stem cells |
| FR2967072B1 (fr) | 2010-11-05 | 2013-03-29 | Univ Dundee | Procede pour ameliorer la production de virus et semences vaccinales influenza |
| WO2012095514A1 (en) | 2011-01-14 | 2012-07-19 | Vivalis | Recombinant protein production system |
| ES3018416T3 (es) | 2011-01-26 | 2025-05-16 | Glaxosmithkline Biologicals Sa | Régimen de inmunización del VRS |
| RS56748B1 (sr) | 2011-05-13 | 2018-03-30 | Glaxosmithkline Biologicals Sa | Pre-fuzioni rsv f antigeni |
| JP2014522842A (ja) | 2011-07-06 | 2014-09-08 | ノバルティス アーゲー | 免疫原性組み合わせ組成物およびその使用 |
| US11058762B2 (en) | 2011-07-06 | 2021-07-13 | Glaxosmithkline Biologicals Sa | Immunogenic compositions and uses thereof |
| TWI575070B (zh) | 2011-07-12 | 2017-03-21 | 傳斯堅公司 | Hbv聚合酶突變體 |
| TW201318637A (zh) | 2011-09-29 | 2013-05-16 | Transgene Sa | 免疫療法組成物及用於治療c型肝炎病毒感染之療程(一) |
| WO2013045668A2 (en) | 2011-09-29 | 2013-04-04 | Transgene Sa | Immunotherapy composition and regimen for treating hepatitis c virus infection |
| US20140348863A1 (en) | 2011-10-12 | 2014-11-27 | Alessia Bianchi | Cmv antigens and uses thereof |
| GB201216121D0 (en) | 2012-09-10 | 2012-10-24 | Novartis Ag | Sample quantification by disc centrifugation |
| EP2768528A1 (en) | 2011-10-20 | 2014-08-27 | Novartis AG | Adjuvanted influenza b virus vaccines for pediatric priming |
| EP2660316A1 (en) | 2012-05-02 | 2013-11-06 | Helmholtz-Zentrum für Infektionsforschung GmbH | Avian cell line and its use in production of protein |
| EP2869842A1 (en) | 2012-07-06 | 2015-05-13 | Novartis AG | Immunogenic compositions and uses thereof |
| WO2014009433A1 (en) | 2012-07-10 | 2014-01-16 | Transgene Sa | Mycobacterium resuscitation promoting factor for use as adjuvant |
| SG11201500171YA (en) | 2012-07-10 | 2015-02-27 | Transgene Sa | Mycobacterial antigen vaccine |
| GB201218195D0 (en) | 2012-10-10 | 2012-11-21 | Istituto Zooprofilattico Sperimentale Delle Venezie | Composition |
| KR20150085843A (ko) | 2012-11-20 | 2015-07-24 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | Rsv f 융합전 삼합체 |
| US20140255447A1 (en) * | 2013-03-05 | 2014-09-11 | Biomune Company | Production of avian embryo cells |
| FR3008992A1 (fr) * | 2013-07-25 | 2015-01-30 | Agronomique Inst Nat Rech | Procede de selection d'une lignee cellulaire permissive pour la replication de virus aviaires |
| EP3092000A1 (en) | 2014-01-09 | 2016-11-16 | Transgene SA | Fusion of heterooligomeric mycobacterial antigens |
| EP2974739A1 (en) | 2014-07-15 | 2016-01-20 | Novartis AG | RSVF trimerization domains |
| EP3031822A1 (en) | 2014-12-08 | 2016-06-15 | Novartis AG | Cytomegalovirus antigens |
| US11118238B2 (en) | 2014-12-17 | 2021-09-14 | Fundación Para La Investigación Mèdica Aplicada | Nucleic acid constructs and gene therapy vectors for use in the treatment of Wilson's disease and other conditions |
| CN107208105A (zh) | 2014-12-17 | 2017-09-26 | 基础应用医学研究基金会 | 用于治疗威尔森病的核酸构建体和基因治疗载体 |
| EP3047856A1 (en) | 2015-01-23 | 2016-07-27 | Novartis AG | Cmv antigens and uses thereof |
| KR20180035807A (ko) | 2015-06-26 | 2018-04-06 | 세퀴러스 유케이 리미티드 | 항원적으로 매치된 인플루엔자 백신 |
| AU2016290603B2 (en) | 2015-07-07 | 2022-06-02 | Seqirus UK Limited | Influenza potency assays |
| CN110506060B (zh) | 2017-03-30 | 2024-05-07 | 昆士兰大学 | 嵌合分子及其用途 |
| CN117821509A (zh) | 2017-04-03 | 2024-04-05 | 编码治疗公司 | 组织选择性转基因表达 |
| WO2019040994A1 (en) | 2017-09-01 | 2019-03-07 | The Australian National University | IMMUNOREGULATOR MOLECULES AND USES THEREOF |
| CN118345115A (zh) | 2017-12-01 | 2024-07-16 | 编码治疗公司 | 工程化的dna结合蛋白 |
| EP3794127A1 (en) | 2018-05-14 | 2021-03-24 | Vivet Therapeutics | Gene therapy vectors comprising s/mar sequences |
| CN112384627A (zh) | 2018-05-30 | 2021-02-19 | 生物医学研究所 | 通过利用内源激活诱导性胞嘧啶脱氨酶改造b淋巴细胞 |
| EP3820884B1 (en) | 2018-07-13 | 2025-09-03 | Valneva SE | Method for rescuing and producing a virus in avian cells |
| AU2019356165A1 (en) | 2018-10-12 | 2021-05-27 | Vivet Therapeutics | Codon-optimized transgene for the treatment of progressive familiar intrahepatic cholestasis type 3 (PFIC3) |
| SG11202104634UA (en) | 2018-11-07 | 2021-06-29 | Vivet Therapeutics | Codon-optimized abcb11 transgene for the treatment of progressive familial intrahepatic cholestasis type 2 (pfic2) |
| CA3118936A1 (en) | 2018-11-16 | 2020-05-22 | Encoded Therapeutics, Inc. | Compositions and methods for treating wilson's disease |
| BR112021009793A2 (pt) * | 2018-11-23 | 2021-08-17 | Valneva Se | produtos alimentícios que compreendem células-tronco aviárias |
| US12467038B2 (en) | 2019-05-22 | 2025-11-11 | Hadasit Medical Research Services And Development Ltd. | Methods of culturing human pluripotent cells |
| SG11202113048SA (en) | 2019-05-29 | 2021-12-30 | Encoded Therapeutics Inc | Compositions and methods for selective gene regulation |
| WO2021001377A1 (en) | 2019-07-02 | 2021-01-07 | Fundacion Para La Investigacion Medica Aplicada | cPLA2e INDUCING AGENTS AND USES THEREOF |
| MX2022000879A (es) | 2019-07-21 | 2022-05-02 | Glaxosmithkline Biologicals Sa | Vacuna viral terapeutica. |
| EP4004018A1 (en) | 2019-07-24 | 2022-06-01 | GlaxoSmithKline Biologicals SA | Modified human cytomegalovirus proteins |
| AU2020344163A1 (en) * | 2019-09-10 | 2022-03-31 | Vital Meat | Avian stem cells for the production of a food product |
| EP4061930A1 (en) | 2019-11-18 | 2022-09-28 | Seqirus Pty Ltd | Method for producing reassortant influenza viruses |
| CA3181024A1 (en) | 2020-08-06 | 2022-02-10 | Fundacion Para La Investigacion Medica Aplicada | Viral particles for use in treating tauopathies such as alzheimer's diseases by gene therapy |
| US20230265456A1 (en) | 2020-08-10 | 2023-08-24 | Fundacion Para La Investigacion Medica Aplicada | Gene therapy vector expressing cyp27a1 for the treatment of cerebrotendinous xanthomatosis |
| IL301255A (en) | 2020-10-09 | 2023-05-01 | UCB Biopharma SRL | Nucleic acid structures, viral vectors and viral particles |
| US20240091382A1 (en) | 2020-12-23 | 2024-03-21 | Vivet Therapeutics | Minimal bile acid inducible promoters for gene therapy |
| EP4032547A1 (en) | 2021-01-20 | 2022-07-27 | GlaxoSmithKline Biologicals S.A. | Hsv1 fce derived fragements for the treatment of hsv |
| IL312340A (en) | 2021-10-28 | 2024-06-01 | UCB Biopharma SRL | Nucleic acid constructs, viral vectors and viral particles |
| US20250101067A1 (en) | 2022-01-28 | 2025-03-27 | Glaxosmithkline Biologicals Sa | Modified human cytomegalovirus proteins |
| CN114480286B (zh) * | 2022-02-16 | 2024-05-31 | 上海健士拜生物科技有限公司 | 无血清悬浮型lmh细胞系及其制备方法和应用 |
| CN116656628A (zh) * | 2023-07-31 | 2023-08-29 | 深圳市卫光生物制品股份有限公司 | 一种痘病毒载体疫苗的制备方法 |
| EP4567102A1 (en) | 2023-12-05 | 2025-06-11 | Suprême | Methods for isolating embryonic stem cells from avian embryonic cells |
| CN118956737A (zh) * | 2024-07-17 | 2024-11-15 | 广州沃亘生物科技有限公司 | 一种长期维持df-1细胞活力的培养基及其用途 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4388298A (en) | 1982-07-14 | 1983-06-14 | The United States Of America As Represented By The Secretary Of Agriculture | Propagation of hemorrhagic enteritis virus in a turkey cell line and vaccine produced |
| WO1990001541A1 (en) | 1988-08-04 | 1990-02-22 | Amrad Corporation Limited | In vitro propagation of embryonic stem cells |
| US5162215A (en) * | 1988-09-22 | 1992-11-10 | Amgen Inc. | Method of gene transfer into chickens and other avian species |
| US5388680A (en) | 1990-10-09 | 1995-02-14 | Intellicall, Inc. | Coin handling system with an improved coin chute |
| DE69230037T2 (de) | 1991-07-12 | 2000-01-05 | Pfizer Inc., New York | Kontinuierliche zellinie sowie impfstoff gegen geflügelinfektion mit kokkidien |
| JPH05227947A (ja) | 1992-01-14 | 1993-09-07 | Rikagaku Kenkyusho | 鳥類原始生殖細胞の分離方法 |
| AU3597093A (en) | 1992-01-27 | 1993-09-01 | Embrex Inc. | Gene transfer in poultry by introduction of embryo cells (in ovo) |
| US5340740A (en) * | 1992-05-15 | 1994-08-23 | North Carolina State University | Method of producing an avian embryonic stem cell culture and the avian embryonic stem cell culture produced by the process |
| WO1994003585A1 (en) | 1992-08-04 | 1994-02-17 | Commonwealth Scientific And Industrial Research Organisation | A method for maintaining embryonic stem cells and avian factor useful for same |
| US5453357A (en) * | 1992-10-08 | 1995-09-26 | Vanderbilt University | Pluripotential embryonic stem cells and methods of making same |
| US5589458A (en) * | 1992-11-13 | 1996-12-31 | Thomas Jefferson University | Compounds that inhibit T cell proliferation and methods for using the same |
| FR2726003B1 (fr) | 1994-10-21 | 2002-10-18 | Agronomique Inst Nat Rech | Milieu de culture de cellules embryonnaires totipotentes aviaires, procede de culture de ces cellules, et cellules embryonnaires totipotentes aviaires |
| US5989805A (en) | 1995-10-27 | 1999-11-23 | Board Of Trustees Operating Michigan State University | Immortal avian cell line to grow avian and animal viruses to produce vaccines |
| FR2749022B1 (fr) | 1996-05-23 | 2001-06-01 | Rhone Merieux | Cellules aviaires immortelles |
| US5691200A (en) | 1996-07-03 | 1997-11-25 | The United States Of America As Represented By The Secretary Of Agriculture | Method to produce granulocyte colony stimulating factor from immortalized avian T lymphocytes and method to produce immortalized cells |
| US5830723A (en) | 1996-08-13 | 1998-11-03 | Regents Of The University Of Minnesota | Method for immortalizing chicken cells |
| US5672485A (en) | 1996-08-13 | 1997-09-30 | Regents Of The University Of Minnesota | Immortalized cell lines for virus growth |
| US6103529A (en) | 1996-10-10 | 2000-08-15 | Life Technologies, Inc. | Animal cell culture media comprising peptides derived from rice |
| PT841392E (pt) | 1996-11-12 | 2004-11-30 | Univ Auburn | Vacina viva atenuada de neospora |
| ATE312167T1 (de) * | 1997-08-04 | 2005-12-15 | Univ Massachusetts | Herstellung embryonischer vogel keimzellinien durch verlängerte kultivierung von pgcs, verwendung desselben zur klonierung und chimerisierung |
| DE69831958T2 (de) * | 1997-08-04 | 2006-07-27 | University of Massachusetts, a Public Institution of Higher Education of The Commonwealth of Massachusetts, Amherst | Primordiale keimzellinie aus vögeln und verfahren zu deren langzeitkultivierung |
| US6406909B1 (en) | 1998-07-10 | 2002-06-18 | Chugai Seiyaku Kabushiki Kaisha | Serum-free medium for culturing animal cells |
| ATE378398T1 (de) * | 1999-02-11 | 2007-11-15 | Hanmi Pharm Ind Co Ltd | Pluripotente embryonale keimzellinie aus vögeln |
| DE60037819T2 (de) * | 1999-08-27 | 2009-01-08 | Invitrogen Corp., Carlsbad | Metallbindende verbindungen und deren verwendung in zusammensetzungen für zellkulturmedien |
| DE19947407C2 (de) | 1999-10-01 | 2002-08-01 | Bayerische Motoren Werke Ag | Datenbussystem für Kraftfahrzeuge |
| WO2002086073A2 (en) * | 2001-04-20 | 2002-10-31 | Memorial Sloan-Kettering Cancer Center | Generation of differentiated tissue from nuclear transfer embryonic stem cells and methods of use |
| FR2836924B1 (fr) | 2002-03-08 | 2005-01-14 | Vivalis | Lignees de cellules aviaires utiles pour la production de substances d'interet |
| DK1520008T3 (da) | 2002-07-09 | 2012-10-15 | Baxter Int | Medium frit for dyreprotein til dyrkning af celler |
| KR101121971B1 (ko) | 2003-07-22 | 2012-03-09 | 비바리스 | 부착성 또는 비부착성 조류 세포주를 이용한폭스바이러스의 생산 |
| EP1500699A1 (en) | 2003-07-22 | 2005-01-26 | Vivalis | Production of vaccinia virus with adherent or non adherent avian cell lines |
| KR100552844B1 (ko) * | 2003-12-31 | 2006-02-21 | 동부아남반도체 주식회사 | 반도체 소자의 제조 방법 |
| FR2884255B1 (fr) | 2005-04-11 | 2010-11-05 | Vivalis | Utilisation de lignees de cellules souches aviaires ebx pour la production de vaccin contre la grippe |
| WO2007135133A1 (en) | 2006-05-19 | 2007-11-29 | Vivalis | Avian cell lines derived from primordial germ cells useful for the production of substances of interest |
| WO2008017704A1 (en) | 2006-08-09 | 2008-02-14 | Vivalis | Method of production of transgenic avian using embryonic stem cells |
| EP1985305A1 (en) | 2007-04-24 | 2008-10-29 | Vivalis | Duck embryonic derived stem cell lines for the production of viral vaccines |
-
2002
- 2002-03-08 FR FR0202945A patent/FR2836924B1/fr not_active Expired - Lifetime
-
2003
- 2003-03-07 CA CA2478125A patent/CA2478125C/fr not_active Expired - Fee Related
- 2003-03-07 CN CNB038101203A patent/CN100562567C/zh not_active Expired - Fee Related
- 2003-03-07 AU AU2003227820A patent/AU2003227820B2/en not_active Expired
- 2003-03-07 DE DE60323468T patent/DE60323468D1/de not_active Expired - Lifetime
- 2003-03-07 WO PCT/FR2003/000735 patent/WO2003076601A1/fr not_active Ceased
- 2003-03-07 CN CN2009101796309A patent/CN101676388B/zh not_active Expired - Lifetime
- 2003-03-07 ES ES03725273T patent/ES2312775T3/es not_active Expired - Lifetime
- 2003-03-07 AT AT03725273T patent/ATE408004T1/de active
- 2003-03-07 DK DK03725273T patent/DK1483369T3/da active
- 2003-03-07 EP EP08163979.1A patent/EP1992687B1/fr not_active Expired - Lifetime
- 2003-03-07 PT PT03725273T patent/PT1483369E/pt unknown
- 2003-03-07 JP JP2003574808A patent/JP5025888B2/ja not_active Expired - Fee Related
- 2003-03-07 SI SI200331354T patent/SI1483369T1/sl unknown
- 2003-03-07 EP EP03725273A patent/EP1483369B1/fr not_active Expired - Lifetime
- 2003-07-24 US US10/625,847 patent/US20040058441A1/en not_active Abandoned
-
2009
- 2009-01-08 US US12/350,781 patent/US20090239297A1/en not_active Abandoned
-
2010
- 2010-03-03 US US12/717,096 patent/US9382513B2/en not_active Expired - Fee Related
-
2011
- 2011-08-09 US US13/206,056 patent/US20110294209A1/en not_active Abandoned
-
2012
- 2012-02-09 JP JP2012026135A patent/JP5784521B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2478125C (fr) | 2013-05-07 |
| US20110294209A1 (en) | 2011-12-01 |
| JP2012110344A (ja) | 2012-06-14 |
| US20120070893A9 (en) | 2012-03-22 |
| CN1649999A (zh) | 2005-08-03 |
| JP5025888B2 (ja) | 2012-09-12 |
| AU2003227820A1 (en) | 2003-09-22 |
| CN101676388B (zh) | 2013-09-04 |
| HK1142094A1 (en) | 2010-11-26 |
| EP1992687A2 (fr) | 2008-11-19 |
| EP1483369B1 (fr) | 2008-09-10 |
| FR2836924A1 (fr) | 2003-09-12 |
| EP1992687B1 (fr) | 2019-06-26 |
| JP5784521B2 (ja) | 2015-09-24 |
| US20090239297A1 (en) | 2009-09-24 |
| WO2003076601A1 (fr) | 2003-09-18 |
| US20040058441A1 (en) | 2004-03-25 |
| WO2003076601A8 (fr) | 2005-05-12 |
| CN100562567C (zh) | 2009-11-25 |
| EP1992687A3 (fr) | 2009-03-25 |
| SI1483369T1 (sl) | 2008-12-31 |
| ES2312775T3 (es) | 2009-03-01 |
| CN101676388A (zh) | 2010-03-24 |
| DK1483369T3 (da) | 2008-12-01 |
| US9382513B2 (en) | 2016-07-05 |
| AU2003227820B2 (en) | 2008-04-03 |
| PT1483369E (pt) | 2008-12-17 |
| FR2836924B1 (fr) | 2005-01-14 |
| US20100221825A1 (en) | 2010-09-02 |
| ATE408004T1 (de) | 2008-09-15 |
| CA2478125A1 (fr) | 2003-09-18 |
| JP2005525803A (ja) | 2005-09-02 |
| EP1483369A1 (fr) | 2004-12-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE408004T1 (de) | Vögelzell-linien und deren verwendung zur herstellung interessanter biologischer substanzen | |
| GB2432846B (en) | Medium and culture of embryonic stem cells | |
| SI1543106T1 (sl) | Postopki in mediji za nadziranje sialilacije proteinov, ki jih proizvajajo sesalske celice | |
| EA199800835A1 (ru) | Среда для культуры клеток млекопитающихся, способ ее получения и смесь компонентов, композиция, способы получения, продуцирования клонального роста, размножения и изменения фенотипа гепатоцитов in vitro, клетки, фармацевтический состав, способы получения рекомбинантной клетки и генного продукта, способы использования клеток, способ трансплантации гепатоцитов, способ испытания лекарственного препарата, способ поддержания жизнеспособности дифференцированных гепатоцитов | |
| DK1097988T3 (da) | Fremgangsmåde til celledyrkning i monolag | |
| DK1155116T3 (da) | Anvendelse af kollagenase i fremstillingen af kulturer af neurale stamceller | |
| DE69720026D1 (de) | Verfahren zur herstellung von d-aminosäuren durch direkte gärung | |
| CN109777773A (zh) | 一种从造血干细胞分化产生nk细胞的方法及其培养基 | |
| BR0316757A (pt) | Composições de meio de cultura de célula, processo para a cultura de célula progenitoras e/ou tronco, processo para a produção de mioblastos, população de células, e uso de mioblastos | |
| ATE364408T1 (de) | Verfahren zur kultivierung von knorpelersatz und biomatrix nach diesem verfahren hergestellt | |
| ATE479743T1 (de) | Verfahren zur herstellung von zellkulturen aus biologischen präparaten für chemotherapeutische und andere assays | |
| ATE510004T1 (de) | In-vitro-techniken zur verwendung mit stammzellen | |
| ATE449162T1 (de) | Herstellung von tcr gamma delta t-zellen | |
| ATE421573T1 (de) | Verfahren zur herstellung von gamma delta t zellen | |
| WO2004033616A8 (de) | Einrichtung zur kultivierung von zellen, insbesondere menschlicher oder tierischer zellen | |
| Kwon et al. | Suspension culture of hematopoietic stem cells in stirred bioreactors | |
| ATE469209T1 (de) | Herstellung und verwendung von basalmembranpartikeln | |
| CN104726400A (zh) | 人多能干细胞向生殖细胞分化的无动物源组分培养方法 | |
| CN109679899A (zh) | 一种人脂肪干细胞与脐带间充质干细胞成软骨能力的比较方法 | |
| WO2004053080A3 (en) | Clonal myeloma cell lines useful for manufacturing proteins in chemically defined media | |
| JPS61124374A (ja) | 酢酸からメタンを生成する微生物の培養法 | |
| JPH034780A (ja) | 肝細胞培養方法 | |
| AU2003251358A1 (en) | Biomimetic urothelium | |
| CN106834127A (zh) | 一种规模化高效培养聚球藻7002的方法 | |
| MD179C2 (ro) | Procedeu de obţinere a biomasei de microalge |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |