ATE479743T1 - Verfahren zur herstellung von zellkulturen aus biologischen präparaten für chemotherapeutische und andere assays - Google Patents
Verfahren zur herstellung von zellkulturen aus biologischen präparaten für chemotherapeutische und andere assaysInfo
- Publication number
- ATE479743T1 ATE479743T1 AT03784853T AT03784853T ATE479743T1 AT E479743 T1 ATE479743 T1 AT E479743T1 AT 03784853 T AT03784853 T AT 03784853T AT 03784853 T AT03784853 T AT 03784853T AT E479743 T1 ATE479743 T1 AT E479743T1
- Authority
- AT
- Austria
- Prior art keywords
- chemotherapeutic
- assay
- cell cultures
- producing cell
- biological preparations
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0693—Tumour cells; Cancer cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2503/00—Use of cells in diagnostics
- C12N2503/02—Drug screening
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Oncology (AREA)
- Toxicology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/208,480 US20040023375A1 (en) | 2002-07-30 | 2002-07-30 | Method for preparing cell cultures from biological specimens for chemotherapeutic and other assays |
PCT/US2003/023888 WO2004015065A2 (en) | 2002-07-30 | 2003-07-30 | Method for preparing cell cultures from biological specimens for chemotherapeutic and other assays |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE479743T1 true ATE479743T1 (de) | 2010-09-15 |
Family
ID=31186831
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03784853T ATE479743T1 (de) | 2002-07-30 | 2003-07-30 | Verfahren zur herstellung von zellkulturen aus biologischen präparaten für chemotherapeutische und andere assays |
Country Status (6)
Country | Link |
---|---|
US (2) | US20040023375A1 (de) |
EP (1) | EP1572969B1 (de) |
AT (1) | ATE479743T1 (de) |
AU (1) | AU2003261308A1 (de) |
DE (1) | DE60334025D1 (de) |
WO (1) | WO2004015065A2 (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040023375A1 (en) * | 2002-07-30 | 2004-02-05 | Precision Therapeutics, Inc. | Method for preparing cell cultures from biological specimens for chemotherapeutic and other assays |
US20040072722A1 (en) | 2002-10-10 | 2004-04-15 | Kornblith Paul L. | Methods for assessing efficacy of chemotherapeutic agents |
US5728541A (en) * | 1996-07-12 | 1998-03-17 | Precision Therapeutics, Inc. | Method for preparing cell cultures from biologial specimens for chemotherapeutic and other assays |
US7276351B2 (en) * | 2003-09-10 | 2007-10-02 | Seahorse Bioscience | Method and device for measuring multiple physiological properties of cells |
US20070087401A1 (en) * | 2003-10-17 | 2007-04-19 | Andy Neilson | Analysis of metabolic activity in cells using extracellular flux rate measurements |
US8658349B2 (en) | 2006-07-13 | 2014-02-25 | Seahorse Bioscience | Cell analysis apparatus and method |
DE102005015953A1 (de) * | 2005-04-07 | 2006-10-12 | Medizinische Hochschule Hannover | Verfahren zur Anreicherung und ex vivo Kultivierung von Brustprimärzellen |
AU2006287175A1 (en) * | 2005-09-01 | 2007-03-08 | Precision Therapeutics, Inc. | Chemo-sensitivity assays using tumor cells exhibiting persistent phenotypic characteristics |
US20100216168A1 (en) * | 2007-03-23 | 2010-08-26 | Precision Therapeutics, Inc. | Methods for evaluating angiogenic potential in culture |
EP2207892A4 (de) | 2007-10-15 | 2010-12-08 | Precision Therapeutics Inc | Verfahren zur selektion aktiver agentien für die krebsbehandlung |
EP2618146B1 (de) | 2008-02-25 | 2015-06-17 | Nestec S.A. | Wirkstoffauswahl zur Brustkrebstherapie unter Verwendung von antikörperbasierten Anordnungen |
US20100311084A1 (en) * | 2008-05-14 | 2010-12-09 | Precision Therapeutics, Inc. | Methods for predicting a patient's response to egfr inhibitors |
US8202702B2 (en) * | 2008-10-14 | 2012-06-19 | Seahorse Bioscience | Method and device for measuring extracellular acidification and oxygen consumption rate with higher precision |
US20110238322A1 (en) * | 2008-11-03 | 2011-09-29 | Precision Therapeutics, Inc. | Methods of simulating chemotherapy for a patient |
WO2011005504A1 (en) | 2009-06-22 | 2011-01-13 | Precision Therapeutics, Inc. | Methods for predicting a cancer patient's response to antifolate therapy |
ES2627909T3 (es) | 2009-07-15 | 2017-08-01 | Diatech Holdings, Inc. | Selección de fármacos para el tratamiento del cáncer gástrico usando matrices basadas en anticuercuerpos |
EP2529238A4 (de) | 2010-01-28 | 2014-10-08 | The Regents Of The University Of Michigan | Hängende tropfvorrichtungen, -systeme und/oder -verfahren |
WO2014078379A2 (en) | 2012-11-13 | 2014-05-22 | Seahorse Bioscience | Apparatus and methods for three-dimensional tissue measurements based on controlled media flow |
CN116809131A (zh) | 2014-06-02 | 2023-09-29 | 安捷伦科技有限公司 | 用于分析生物样本的单列微板系统和载体 |
Family Cites Families (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US168679A (en) * | 1875-10-11 | Improvement in variable measures | ||
US192638A (en) * | 1877-07-03 | Improvement in umbrella tip-cups | ||
US4423145A (en) * | 1981-05-07 | 1983-12-27 | Stampfer Martha R | Enhanced growth medium and method for culturing human mammary epithelial cells |
US4668618A (en) * | 1981-09-14 | 1987-05-26 | Thornthwaite Jerry T | Nuclear isolation medium and procedure for separating cell nuclei |
US4937187A (en) * | 1983-02-04 | 1990-06-26 | Brown University Research Foundation | Methods for separating malignant cells from clinical specimens |
US4559299A (en) * | 1983-02-04 | 1985-12-17 | Brown University Research Foundation Inc. | Cytotoxicity assays in cell culturing devices |
US4816395A (en) * | 1985-12-19 | 1989-03-28 | Peralta Cancer Research Institute | Method for predicting chemosensitivity of anti-cancer drugs |
US4937182A (en) * | 1985-12-19 | 1990-06-26 | Peralta Cancer Research Institute | Method for predicting chemosensitivity of anti-cancer drugs |
US5266480A (en) * | 1986-04-18 | 1993-11-30 | Advanced Tissue Sciences, Inc. | Three-dimensional skin culture system |
US4996145A (en) * | 1987-10-27 | 1991-02-26 | Oncotech Incorporated | Method for detecting immune-mediated cytotoxicity |
US5242806A (en) * | 1990-05-07 | 1993-09-07 | Baxter Diagnostics Inc. | Method for conducting the cytotoxicity assays on tumor cells |
US5874218A (en) * | 1990-06-11 | 1999-02-23 | Nexstar Pharmaceuticals, Inc. | Method for detecting a target compound in a substance using a nucleic acid ligand |
US5747469A (en) * | 1991-03-06 | 1998-05-05 | Board Of Regents, The University Of Texas System | Methods and compositions comprising DNA damaging agents and p53 |
US5270172A (en) * | 1991-04-26 | 1993-12-14 | Dekk-Tek, Inc. | Method to predict tumor response to therapy |
US5407653A (en) * | 1991-06-26 | 1995-04-18 | Brigham And Women's Hospital | Evaluation of the multidrug resistance phenotype |
WO1993009176A2 (en) * | 1991-10-29 | 1993-05-13 | Clover Consolidated, Limited | Crosslinkable polysaccharides, polycations and lipids useful for encapsulation and drug release |
WO1994000470A1 (en) * | 1992-06-30 | 1994-01-06 | The Wistar Institute Of Anatomy And Biology | DEVELOPMENTAL EMBRYONIC MOUSE cDNA LIBRARIES |
US5585265A (en) * | 1992-11-30 | 1996-12-17 | Gillette Company | Human corneal epithelial cell lines with extended lifespan |
US5607918A (en) * | 1995-03-01 | 1997-03-04 | Ludwig Institute For Cancer Research | Vascular endothelial growth factor-B and DNA coding therefor |
US5888765A (en) * | 1995-06-23 | 1999-03-30 | President And Fellows Of Harvard College | Endothelial-cell specific promoter |
US6274576B1 (en) * | 1995-06-27 | 2001-08-14 | The Henry Jackson Foundation For The Advancement Of Military Medicine | Method of dynamic retardation of cell cycle kinetics to potentiate cell damage |
US6020473A (en) * | 1995-08-25 | 2000-02-01 | Genentech, Inc. | Nucleic acids encoding variants of vascular endothelial cell growth factor |
US5942385A (en) * | 1996-03-21 | 1999-08-24 | Sugen, Inc. | Method for molecular diagnosis of tumor angiogenesis and metastasis |
US5728541A (en) * | 1996-07-12 | 1998-03-17 | Precision Therapeutics, Inc. | Method for preparing cell cultures from biologial specimens for chemotherapeutic and other assays |
US20040023375A1 (en) | 2002-07-30 | 2004-02-05 | Precision Therapeutics, Inc. | Method for preparing cell cultures from biological specimens for chemotherapeutic and other assays |
US6416967B2 (en) * | 1996-07-12 | 2002-07-09 | Precision Therapeutics, Inc. | Method of using multicellular particulates to analyze malignant or hyperproliferative tissue |
US20020168679A1 (en) * | 1998-06-11 | 2002-11-14 | Gregory J. Naus | Staining agents and protocols for characterizing malignant cells in culture |
US20040072722A1 (en) * | 2002-10-10 | 2004-04-15 | Kornblith Paul L. | Methods for assessing efficacy of chemotherapeutic agents |
US6008007A (en) * | 1997-01-31 | 1999-12-28 | Oncotech, Inc. | Radiation resistance assay for predicting treatment response and clinical outcome |
US5840507A (en) * | 1997-03-19 | 1998-11-24 | Oncotech, Inc. | Methods for cancer prognosis and diagnosis |
US5972639A (en) * | 1997-07-24 | 1999-10-26 | Irori | Fluorescence-based assays for measuring cell proliferation |
US6074874A (en) * | 1997-08-29 | 2000-06-13 | University Of Pittsburgh | Epithelial cell cultures for in vitro testing |
US6111092A (en) * | 1998-06-03 | 2000-08-29 | Millennium Pharmaceuticals, Inc. | Nucleic acid molecules encoding DRT111 and uses thereof |
US6664062B1 (en) * | 1998-07-20 | 2003-12-16 | Nuvelo, Inc. | Thymidylate synthase gene sequence variances having utility in determining the treatment of disease |
WO2000022142A2 (en) * | 1998-10-13 | 2000-04-20 | Onyx Pharmaceuticals, Inc. | Cell signaling polypeptides and nucleic acids |
WO2000052204A2 (en) * | 1999-02-22 | 2000-09-08 | Orntoft Torben F | Gene expression in bladder tumors |
EP1059352A1 (de) * | 1999-06-08 | 2000-12-13 | Oncodia AG | Langzeitkultur humaner Karzinome |
WO2001033228A2 (en) * | 1999-11-03 | 2001-05-10 | Oncotech, Inc. | Cancer diagnosis employing cell-sorting and gene-profiles |
WO2001035316A2 (en) | 1999-11-10 | 2001-05-17 | Structural Bioinformatics, Inc. | Computationally derived protein structures in pharmacogenomics |
WO2001065994A2 (en) | 2000-03-06 | 2001-09-13 | Technion Research And Development Foundation Ltd. | Method of and kit for assessing responsiveness of cancer patients to antifolate chemotherapy |
DE60135366D1 (de) | 2000-04-18 | 2008-09-25 | Virco Bvba | Methode zur bestimmung der resistenz gegen medikamente |
WO2002033117A2 (en) | 2000-10-18 | 2002-04-25 | Precision Therapeutics, Inc. | Method for tandem genomic/proteomic analyses of proliferating cells |
ATE449184T1 (de) | 2001-01-12 | 2009-12-15 | Univ Washington | Mdr1-varianten und verfahren zu ihrer verwendung |
US20040086888A1 (en) * | 2001-10-18 | 2004-05-06 | Kornblith Paul L | Method for tandem genomic/proteomic analysis of proliferating cells |
WO2003044215A2 (en) | 2001-11-20 | 2003-05-30 | Oncomedx, Inc. | Methods for evaluating drug-resistance gene expression in the cancer patient |
-
2002
- 2002-07-30 US US10/208,480 patent/US20040023375A1/en not_active Abandoned
-
2003
- 2003-07-30 AT AT03784853T patent/ATE479743T1/de not_active IP Right Cessation
- 2003-07-30 WO PCT/US2003/023888 patent/WO2004015065A2/en not_active Application Discontinuation
- 2003-07-30 EP EP03784853A patent/EP1572969B1/de not_active Expired - Lifetime
- 2003-07-30 AU AU2003261308A patent/AU2003261308A1/en not_active Abandoned
- 2003-07-30 DE DE60334025T patent/DE60334025D1/de not_active Expired - Lifetime
-
2006
- 2006-11-13 US US11/595,967 patent/US7972769B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1572969A2 (de) | 2005-09-14 |
DE60334025D1 (de) | 2010-10-14 |
US7972769B2 (en) | 2011-07-05 |
AU2003261308A1 (en) | 2004-02-25 |
US20070059821A1 (en) | 2007-03-15 |
WO2004015065A3 (en) | 2006-10-05 |
US20040023375A1 (en) | 2004-02-05 |
EP1572969A4 (de) | 2007-06-06 |
AU2003261308A8 (en) | 2004-02-25 |
EP1572969B1 (de) | 2010-09-01 |
WO2004015065A2 (en) | 2004-02-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE479743T1 (de) | Verfahren zur herstellung von zellkulturen aus biologischen präparaten für chemotherapeutische und andere assays | |
ATE365793T1 (de) | Verfahren zur isolierung und kulturexpansion mesenchymaler stamm-/vorläuferzellen aus nabelschnurblut sowie verfahren zur differenzierung von aus nabelschnurblut stammenden mesenchymalen stamm-/vorläuferzellen in unterschiedliche mesenchymgewebe | |
WO2001081549A3 (en) | Hepatocyte lineage cells derived from pluripotent stem cells | |
DE602004025805D1 (de) | Verfahren zur herstellung von antikörpern | |
DE602004014158D1 (de) | Verfahren zur herstellung von l-lysin oder l-threonin unter verwendung von escherichia-bakterien mit abgeschwächter malatenzymaktivität | |
DE60323468D1 (de) | Vögelzell-linien und deren verwendung zur herstellung interessanter biologischer substanzen | |
RU2011124900A (ru) | Культура плюрипотентных стволовых клеток на микроносителях | |
DE602007012290D1 (de) | Mischzell-populationen für die gewebereparatur und trenntechnik für die zellaufbereitung | |
HK1093755A1 (en) | Method for differentiating mesenchymal stem cell into neural cell | |
TW200636068A (en) | A method of culturing a cell and use of the same | |
SG158025A1 (en) | Growth medium c. histolyticum without ingredients of mamalian sources | |
ATE430807T1 (de) | Verfahren zur kultivierung von circovirus | |
ATE517176T1 (de) | Verfahren zur kultivierung von geschmackszellen aus säugern | |
WO2004090096A3 (en) | Methods for neural differentiation of embryonic stem cells using protease passaging techniques | |
DE69935978D1 (de) | Kulturmedium zur kultivierung tierischer zellen und verfahren zur herstellung von proteinen durch dessen verwendung | |
WO2003010304A3 (de) | Verfahren zur herstellung isolierter zellkulturen, kulturmedium zur kultivierung von zellkulturen und zellkultur | |
ATE336567T1 (de) | Zellkulturmedium | |
ATE530657T1 (de) | Verfahren zur herstellung von zellinien mit latentem immunschwächevirus | |
ATE521697T1 (de) | Verfahren zum wachstum von menschlichen bindehautgewebeäquivalenten für die forschung, die klinische augenoberflächentransplantation und die geweberekonstruktion | |
NO20006051L (no) | Fremgangsmåte for fremstilling av dyrkning av celleaggregater referert til som primmorfer fra dissosierte celler fra svamper, koraller og andre invertebrater, samt anvendelse av disse | |
ATE469209T1 (de) | Herstellung und verwendung von basalmembranpartikeln | |
ATE201908T1 (de) | Verfahren zur herstellung von riboflavin mittels mikroorganismen mit veränderter isocitratlyase- aktivität | |
FR2848565B1 (fr) | Lignee de cellules dendritiques gen2.2 | |
ATE449162T1 (de) | Herstellung von tcr gamma delta t-zellen | |
WO2004078915A3 (en) | Cell culture |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |