ATE521697T1 - Verfahren zum wachstum von menschlichen bindehautgewebeäquivalenten für die forschung, die klinische augenoberflächentransplantation und die geweberekonstruktion - Google Patents
Verfahren zum wachstum von menschlichen bindehautgewebeäquivalenten für die forschung, die klinische augenoberflächentransplantation und die geweberekonstruktionInfo
- Publication number
- ATE521697T1 ATE521697T1 AT03721475T AT03721475T ATE521697T1 AT E521697 T1 ATE521697 T1 AT E521697T1 AT 03721475 T AT03721475 T AT 03721475T AT 03721475 T AT03721475 T AT 03721475T AT E521697 T1 ATE521697 T1 AT E521697T1
- Authority
- AT
- Austria
- Prior art keywords
- tissue
- equivalents
- research
- eye surface
- human connective
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/12—Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
- C12N2500/14—Calcium; Ca chelators; Calcitonin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/70—Undefined extracts
- C12N2500/80—Undefined extracts from animals
- C12N2500/84—Undefined extracts from animals from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/01—Modulators of cAMP or cGMP, e.g. non-hydrolysable analogs, phosphodiesterase inhibitors, cholera toxin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/11—Epidermal growth factor [EGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/33—Insulin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/39—Steroid hormones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
- C12N2533/92—Amnion; Decellularised dermis or mucosa
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36815802P | 2002-03-29 | 2002-03-29 | |
PCT/US2003/009392 WO2003084431A2 (en) | 2002-03-29 | 2003-03-28 | Method for growth of human conjunctival tissue equivalents for research, clinical ocular surface transplantation and tissue engineering |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE521697T1 true ATE521697T1 (de) | 2011-09-15 |
Family
ID=28791886
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03721475T ATE521697T1 (de) | 2002-03-29 | 2003-03-28 | Verfahren zum wachstum von menschlichen bindehautgewebeäquivalenten für die forschung, die klinische augenoberflächentransplantation und die geweberekonstruktion |
Country Status (7)
Country | Link |
---|---|
US (2) | US7049139B2 (de) |
EP (1) | EP1499710B1 (de) |
CN (1) | CN1649998A (de) |
AT (1) | ATE521697T1 (de) |
AU (1) | AU2003224785B2 (de) |
HK (1) | HK1080111A1 (de) |
WO (1) | WO2003084431A2 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2003224785B2 (en) * | 2002-03-29 | 2008-12-11 | Singapore Eye Research Institute | Method for growth of human conjunctival tissue equivalents for research, clinical ocular surface transplantation and tissue engineering |
CN1720055A (zh) * | 2002-10-04 | 2006-01-11 | 组织技术公司 | 视网膜上皮细胞在羊膜上的培养和移植 |
DE102005027355A1 (de) * | 2005-06-13 | 2006-12-14 | Femtotechnologies Gmbh | Verfahren zum Bearbeiten eines organischen Materials |
EP1987133A2 (de) * | 2006-02-24 | 2008-11-05 | Reliance Life Sciences Pvt., Ltd. | Augeninnengewebesystem |
US8372437B2 (en) | 2006-08-17 | 2013-02-12 | Mimedx Group, Inc. | Placental tissue grafts |
JPWO2008105454A1 (ja) | 2007-02-28 | 2010-06-03 | 千寿製薬株式会社 | ラクリチン高発現細胞 |
US8574567B2 (en) | 2007-05-03 | 2013-11-05 | The Brigham And Women's Hospital, Inc. | Multipotent stem cells and uses thereof |
EP2155860B1 (de) | 2007-05-03 | 2014-08-27 | The Brigham and Women's Hospital, Inc. | Multipotente stammzellen und ihre verwendung |
EP2151492B1 (de) * | 2007-05-11 | 2015-03-04 | Dai Nippon Printing Co., Ltd. | Zellschicht mit guter dimensionaler stabilität, verfahren zu ihrer herstellung und zellkulturträger zur verwendung für das verfahren |
EP3189731B1 (de) | 2007-09-07 | 2020-01-29 | MiMedx Group, Inc. | Plazentale gewebetransplantate und verfahren zur herstellung und verwendung davon |
EP2225361A1 (de) * | 2007-11-28 | 2010-09-08 | Organogenesis, Inc. | Biotechnisch konstruierte gewebekonstrukte und verfahren zur herstellung und verwendung |
CN104263699A (zh) * | 2014-09-19 | 2015-01-07 | 江苏华亿细胞组织工程有限公司 | 细胞移植用临床治疗级真皮多能干细胞规模化制备培养方法 |
CN104312970A (zh) * | 2014-09-19 | 2015-01-28 | 朱宁文 | 一种细胞治疗用临床治疗级表皮干细胞应用人类细胞外基质筛选及规模化培养制备方法 |
Family Cites Families (32)
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US3249504A (en) | 1962-03-13 | 1966-05-03 | Becton Dickinson Co | Multiple unit tissue culture preparation and method of preparing same |
US4456687A (en) | 1978-11-16 | 1984-06-26 | President And Fellows Of Harvard College | Agents for promoting growth of epithelial cells |
US4443546A (en) | 1980-07-07 | 1984-04-17 | The Beth Israel Hospital Association | Process and composition for propagating mammalian cells |
US5166048A (en) | 1981-03-02 | 1992-11-24 | Soll David B | Protection of human corneal endothelial cells |
US4423145A (en) | 1981-05-07 | 1983-12-27 | Stampfer Martha R | Enhanced growth medium and method for culturing human mammary epithelial cells |
US4940666A (en) | 1983-07-15 | 1990-07-10 | University Patents, Inc. | Process and defined medium for growth of human epidermal keratinocyte cells |
US4673649A (en) | 1983-07-15 | 1987-06-16 | University Patents, Inc. | Process and defined medium for growth of human epidermal keratinocyte cells |
US5976878A (en) * | 1987-04-28 | 1999-11-02 | The Regents Of The University Of California | Method and apparatus for preparing composite skin replacement |
DE3801236A1 (de) | 1988-01-18 | 1989-07-27 | Boehringer Mannheim Gmbh | Pentosansulfat-medium |
GB8803697D0 (en) | 1988-02-17 | 1988-03-16 | Deltanine Research Ltd | Clinical developments using amniotic membrane cells |
AU621972B2 (en) | 1988-12-14 | 1992-03-26 | United States of America, as represented by the Secretary, U.S. Department of Commerce, The | Cell culture medium for human liver epithelial cell line |
CA2018228C (en) | 1989-06-05 | 1996-02-27 | Nancy L. Parenteau | Cell culture systems and media |
US5292655A (en) | 1990-01-29 | 1994-03-08 | Wille Jr John J | Method for the formation of a histologically-complete skin substitute |
US5834312A (en) * | 1990-01-29 | 1998-11-10 | Hy-Gene, Inc. | Process and media for the growth of human epithelia |
US5328844A (en) | 1990-05-09 | 1994-07-12 | University Of Colorado Foundation, Inc. | Culture media for mammalian cells |
US5811094A (en) | 1990-11-16 | 1998-09-22 | Osiris Therapeutics, Inc. | Connective tissue regeneration using human mesenchymal stem cell preparations |
JPH0789908B2 (ja) * | 1991-02-28 | 1995-10-04 | 倉敷紡績株式会社 | 動物細胞培養用無血清培地 |
US6045791A (en) | 1992-03-06 | 2000-04-04 | Photogenesis, Inc. | Retinal pigment epithelium transplantation |
DE4401606A1 (de) * | 1994-01-20 | 1995-07-27 | Wacker Chemie Gmbh | Hitzestabilisierte, zu Elastomeren vernetzbare Organopolysiloxanmassen |
US5405772A (en) | 1993-06-18 | 1995-04-11 | Amgen Inc. | Medium for long-term proliferation and development of cells |
US5610281A (en) * | 1994-05-03 | 1997-03-11 | Brigham & Women's Hospital, Inc. | Antibodies for modulating heterotypic E-cadherin interactions with human T lymphocytes |
US5610699A (en) | 1994-07-12 | 1997-03-11 | Xerox Corporation | Photoreceptor cleaning apparatus and method |
US5650279A (en) * | 1995-01-27 | 1997-07-22 | Allergan, Inc. | Gene sequence induced in skin by retinoids |
US6043092A (en) | 1996-03-18 | 2000-03-28 | University Of Pittsburgh | Cell culture media for mammalian cells |
CA2216439A1 (en) | 1996-09-25 | 1998-03-25 | Derek Van Der Kooy | Pharmaceuticals containing retinal stem cells |
US6152142A (en) * | 1997-02-28 | 2000-11-28 | Tseng; Scheffer C. G. | Grafts made from amniotic membrane; methods of separating, preserving, and using such grafts in surgeries |
US5972332A (en) * | 1997-04-16 | 1999-10-26 | The Regents Of The University Of Michigan | Wound treatment with keratinocytes on a solid support enclosed in a porous material |
US5932205A (en) | 1997-07-24 | 1999-08-03 | Wang; Ming X. | Biochemical contact lens for treating photoablated corneal tissue |
US6143315A (en) | 1997-07-24 | 2000-11-07 | Wang; Ming X. | Biochemical contact lens for treating injured corneal tissue |
US20020039788A1 (en) * | 2000-02-29 | 2002-04-04 | Isseroff Roslyn R. | Corneal epithelial graft composites |
US7052690B2 (en) * | 2000-10-05 | 2006-05-30 | The Schepens Eye Research Institute, Inc. | Culture of goblet cells |
AU2003224785B2 (en) * | 2002-03-29 | 2008-12-11 | Singapore Eye Research Institute | Method for growth of human conjunctival tissue equivalents for research, clinical ocular surface transplantation and tissue engineering |
-
2003
- 2003-03-28 AU AU2003224785A patent/AU2003224785B2/en not_active Ceased
- 2003-03-28 CN CNA038096579A patent/CN1649998A/zh active Pending
- 2003-03-28 EP EP03721475A patent/EP1499710B1/de not_active Expired - Lifetime
- 2003-03-28 WO PCT/US2003/009392 patent/WO2003084431A2/en not_active Application Discontinuation
- 2003-03-28 AT AT03721475T patent/ATE521697T1/de not_active IP Right Cessation
- 2003-03-31 US US10/401,788 patent/US7049139B2/en not_active Expired - Fee Related
-
2006
- 2006-01-04 HK HK06100085.0A patent/HK1080111A1/zh unknown
- 2006-04-06 US US11/398,557 patent/US7611895B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20040009590A1 (en) | 2004-01-15 |
EP1499710B1 (de) | 2011-08-24 |
AU2003224785B2 (en) | 2008-12-11 |
HK1080111A1 (zh) | 2006-04-21 |
US7049139B2 (en) | 2006-05-23 |
WO2003084431A3 (en) | 2004-04-15 |
CN1649998A (zh) | 2005-08-03 |
WO2003084431A2 (en) | 2003-10-16 |
US7611895B2 (en) | 2009-11-03 |
AU2003224785A1 (en) | 2003-10-20 |
EP1499710A4 (de) | 2005-08-31 |
US20060177927A1 (en) | 2006-08-10 |
EP1499710A2 (de) | 2005-01-26 |
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Legal Events
Date | Code | Title | Description |
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |