DE60224052T2 - Aminpolymere zur behandlung von gicht und zur senkung des harnsäuregehaltes - Google Patents

Aminpolymere zur behandlung von gicht und zur senkung des harnsäuregehaltes Download PDF

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Publication number
DE60224052T2
DE60224052T2 DE60224052T DE60224052T DE60224052T2 DE 60224052 T2 DE60224052 T2 DE 60224052T2 DE 60224052 T DE60224052 T DE 60224052T DE 60224052 T DE60224052 T DE 60224052T DE 60224052 T2 DE60224052 T2 DE 60224052T2
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DE
Germany
Prior art keywords
use according
polymer
solid
water
uric acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60224052T
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German (de)
English (en)
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DE60224052D1 (de
Inventor
Stephen Randall Arlington Holmes-Farley
Steven K. Sudbury BURKE
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Genzyme Corp
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Genzyme Corp
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Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of DE60224052D1 publication Critical patent/DE60224052D1/de
Application granted granted Critical
Publication of DE60224052T2 publication Critical patent/DE60224052T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Dental Preparations (AREA)
  • Adhesives Or Adhesive Processes (AREA)
DE60224052T 2001-04-18 2002-04-10 Aminpolymere zur behandlung von gicht und zur senkung des harnsäuregehaltes Expired - Lifetime DE60224052T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US28444501P 2001-04-18 2001-04-18
US284445P 2001-04-18
US30556701P 2001-07-13 2001-07-13
US305567P 2001-07-13
PCT/US2002/011492 WO2002085381A1 (en) 2001-04-18 2002-04-10 Method for treating gout and binding uric acid

Publications (2)

Publication Number Publication Date
DE60224052D1 DE60224052D1 (de) 2008-01-24
DE60224052T2 true DE60224052T2 (de) 2008-11-06

Family

ID=26962624

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60224052T Expired - Lifetime DE60224052T2 (de) 2001-04-18 2002-04-10 Aminpolymere zur behandlung von gicht und zur senkung des harnsäuregehaltes

Country Status (9)

Country Link
US (2) US20030039627A1 (cg-RX-API-DMAC7.html)
EP (1) EP1416942B1 (cg-RX-API-DMAC7.html)
JP (1) JP2004528332A (cg-RX-API-DMAC7.html)
AT (1) ATE380553T1 (cg-RX-API-DMAC7.html)
BR (1) BR0209133A (cg-RX-API-DMAC7.html)
CA (1) CA2444347A1 (cg-RX-API-DMAC7.html)
DE (1) DE60224052T2 (cg-RX-API-DMAC7.html)
MX (1) MXPA03009571A (cg-RX-API-DMAC7.html)
WO (1) WO2002085381A1 (cg-RX-API-DMAC7.html)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
WO2004037274A1 (en) * 2002-10-22 2004-05-06 Genzyme Corporation Amine polymers for promoting bone formation
WO2004099288A1 (en) * 2003-05-09 2004-11-18 Carlsberg A/S Polyethyleneimine polymers
US7335795B2 (en) 2004-03-22 2008-02-26 Ilypsa, Inc. Crosslinked amine polymers
US7385012B2 (en) 2003-11-03 2008-06-10 Ilypsa, Inc. Polyamine polymers
US7449605B2 (en) * 2003-11-03 2008-11-11 Ilypsa, Inc. Crosslinked amine polymers
US7767768B2 (en) * 2003-11-03 2010-08-03 Ilypsa, Inc. Crosslinked amine polymers
US7608674B2 (en) 2003-11-03 2009-10-27 Ilypsa, Inc. Pharmaceutical compositions comprising cross-linked small molecule amine polymers
US7459502B2 (en) * 2003-11-03 2008-12-02 Ilypsa, Inc. Pharmaceutical compositions comprising crosslinked polyamine polymers
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
WO2006072054A1 (en) * 2004-12-30 2006-07-06 Genzyme Corporation Zinc-containing treatments for hyperphosphatemia
WO2006121995A2 (en) * 2005-05-09 2006-11-16 Tap Pharmaceutical Products, Inc. Methods for treating nephrolithiasis
JP2009507019A (ja) * 2005-09-02 2009-02-19 ジェンザイム・コーポレーション リン酸塩を除去する方法およびそれに使用される重合体
DK1924246T3 (en) 2005-09-15 2016-01-18 Genzyme Corp PORTION LETTER DEFINITION OF amine polymers
BRPI0618352A2 (pt) * 2005-11-08 2011-08-23 Genzyme Corp composições farmacêuticas e métodos de tratamento da hiperfosfatemia em um paciente
EP2016114A2 (en) * 2006-05-05 2009-01-21 Genzyme Corporation Amine condensation polymers as phosphate sequestrants
US20100135950A1 (en) * 2006-07-05 2010-06-03 Genzyme Corporation Iron(II)-Containing Treatments for Hyperphosphatemia
US20100124542A1 (en) * 2006-07-18 2010-05-20 Genzyme Corporation Amine dendrimers
BRPI0717545A2 (pt) 2006-09-29 2013-10-22 Gezyme Corp Composição farmacêutica, método para tratar uma doença, polímero de amida, rede de polímero, e, método para preparar um polímero de amida
US20090124623A1 (en) * 2006-11-13 2009-05-14 Christopher Lademacher Methods for preserving and/or increasing renal function using xanthine oxidoreductase inhibitors
WO2008064015A1 (en) * 2006-11-13 2008-05-29 Takeda Pharmaceuticals North America Methods for preserving renal function using xanthine oxidoreductase inhibitors
BRPI0720234A2 (pt) * 2006-12-14 2013-12-24 Genzyme Corp Composição farmacêutica
RU2009131454A (ru) * 2007-01-19 2011-02-27 Такеда Фармасьютикалз Норт Америка, Инк. (Us) Способы предупреждения или уменьшения числа обострений подагры с применением ингибиторов ксантиноксидоредуктазы и противовоспалительных средств
JP2010519298A (ja) * 2007-02-23 2010-06-03 ゲンズイメ コーポレーション アミンポリマー組成物
US20100196305A1 (en) * 2007-03-08 2010-08-05 Dhal Pradeep K Sulfone polymer compositions
EP2152277A1 (en) * 2007-04-27 2010-02-17 Genzyme Corporation Amido-amine dendrimer compositions
EP2217215A1 (en) * 2007-12-14 2010-08-18 Genzyme Corporation Coated pharmaceutical compositions
WO2009154747A1 (en) * 2008-06-20 2009-12-23 Genzyme Corporation Pharmaceutical compositions
US20100311756A1 (en) * 2009-01-22 2010-12-09 Takeda Pharmaceuticals North America, Inc. Methods for delaying the progression of at least one of cardiac hypertrophy, cardiac remodeling or left ventricular function or the onset of heart failure in subjects in need of treatment thereof
KR101797936B1 (ko) 2010-09-10 2017-11-15 다케다 파마슈티칼스 유에스에이, 인코포레이티드 테오필린과 페북소스타트의 병용 치료 방법
KR20210131457A (ko) 2013-06-05 2021-11-02 트리시다, 인크. 경구 투여를 위한 양성자-결합 중합체
ES2787218T3 (es) 2014-12-10 2020-10-15 Tricida Inc Polímeros de unión de protones para la administración oral
EP3452028A4 (en) 2016-05-06 2020-04-15 Tricida Inc. COMPOSITIONS AND METHOD FOR TREATING ACID-BASED DISORDERS
BR112019013364A2 (pt) 2016-12-28 2020-04-14 Fujifilm Corp emulsão de polímero contendo átomo de nitrogênio ou sal do mesmo, método de produção para o mesmo e método de produção para partículas
EP3698799B1 (en) 2017-10-16 2022-01-26 FUJIFILM Corporation Hyperphosphatemia treatment agent
SG11202003451UA (en) 2017-11-03 2020-05-28 Tricida Inc Compositions for and method of treating acid-base disorders
ES2995007T3 (en) * 2021-08-24 2025-02-05 Waterstone Pharmaceuticals Wuhan Co Ltd Polymers, compositions and methods for treating hyperuricemia
EP4164659B1 (en) * 2021-08-24 2024-03-27 Waterstone Pharmaceuticals (Wuhan) Co., Ltd. Polymers, compositions and methods for treating hyperuricemia

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4271191A (en) * 1979-12-19 1981-06-02 Pierre Fabre S.A. Method of treating hyperuricemia and gout
DE3727082A1 (de) * 1987-08-14 1989-02-23 Goedecke Ag Pharmazeutische zubereitungen zur behandlung der urolithiasis
JP4358303B2 (ja) * 1996-10-23 2009-11-04 ダウ グローバル テクノロジーズ インコーポレイティド 食物ホスフェート又はオキサレート吸収を低下させるための水溶性ポリマー
US5985938A (en) * 1997-11-05 1999-11-16 Geltex Pharmaceuticals, Inc. Method for reducing oxalate
WO2002085380A1 (en) * 2001-04-18 2002-10-31 Geltex Pharmaceuticals, Inc. Method for treating gout and reducing serum uric acid

Also Published As

Publication number Publication date
EP1416942B1 (en) 2007-12-12
DE60224052D1 (de) 2008-01-24
WO2002085381A1 (en) 2002-10-31
JP2004528332A (ja) 2004-09-16
ATE380553T1 (de) 2007-12-15
CA2444347A1 (en) 2002-10-31
MXPA03009571A (es) 2004-02-12
US20030039627A1 (en) 2003-02-27
EP1416942A1 (en) 2004-05-12
US20080112918A1 (en) 2008-05-15
BR0209133A (pt) 2004-06-15

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