DE60222662T2 - Verwendung von l-azetylcarnitin zur herstellung eines medikaments zur präventiven post-chirurgischen schmerzbehandlung - Google Patents

Verwendung von l-azetylcarnitin zur herstellung eines medikaments zur präventiven post-chirurgischen schmerzbehandlung Download PDF

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Publication number
DE60222662T2
DE60222662T2 DE60222662T DE60222662T DE60222662T2 DE 60222662 T2 DE60222662 T2 DE 60222662T2 DE 60222662 T DE60222662 T DE 60222662T DE 60222662 T DE60222662 T DE 60222662T DE 60222662 T2 DE60222662 T2 DE 60222662T2
Authority
DE
Germany
Prior art keywords
acetyl
carnitine
treatment
acid
test
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60222662T
Other languages
German (de)
English (en)
Other versions
DE60222662D1 (de
Inventor
Menotti Calvani
Luigi Mosconi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Industrie Farmaceutiche Riunite SpA filed Critical Sigma Tau Industrie Farmaceutiche Riunite SpA
Publication of DE60222662D1 publication Critical patent/DE60222662D1/de
Application granted granted Critical
Publication of DE60222662T2 publication Critical patent/DE60222662T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE60222662T 2001-05-29 2002-05-24 Verwendung von l-azetylcarnitin zur herstellung eines medikaments zur präventiven post-chirurgischen schmerzbehandlung Expired - Lifetime DE60222662T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITRM20010293 2001-05-29
IT2001RM000293A ITRM20010293A1 (it) 2001-05-29 2001-05-29 Uso della acetil-l-carnetina per la preparazione di un medicamento per la prevenzione del dolore.
PCT/IT2002/000336 WO2002096409A1 (en) 2001-05-29 2002-05-24 Use of acetyl l-carnitine for the preparation of a medication for the preventive therapy for pain

Publications (2)

Publication Number Publication Date
DE60222662D1 DE60222662D1 (de) 2007-11-08
DE60222662T2 true DE60222662T2 (de) 2008-06-26

Family

ID=11455557

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60222662T Expired - Lifetime DE60222662T2 (de) 2001-05-29 2002-05-24 Verwendung von l-azetylcarnitin zur herstellung eines medikaments zur präventiven post-chirurgischen schmerzbehandlung

Country Status (18)

Country Link
US (2) US20040152781A1 (https=)
EP (1) EP1399141B1 (https=)
JP (1) JP4287660B2 (https=)
KR (1) KR100873748B1 (https=)
AT (1) ATE374021T1 (https=)
CA (1) CA2448242C (https=)
CY (1) CY1107037T1 (https=)
CZ (1) CZ20033220A3 (https=)
DE (1) DE60222662T2 (https=)
DK (1) DK1399141T3 (https=)
ES (1) ES2290292T3 (https=)
HU (1) HUP0401294A3 (https=)
IT (1) ITRM20010293A1 (https=)
MX (1) MXPA03010919A (https=)
PL (1) PL367616A1 (https=)
PT (1) PT1399141E (https=)
SK (1) SK287559B6 (https=)
WO (1) WO2002096409A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20040606A1 (it) 2004-12-13 2005-03-13 Sigma Tau Ind Farmaceuti Uso della acetil l-carnitina per il trattamento della sindrome fibromialgica.
JP5685362B2 (ja) * 2005-04-26 2015-03-18 シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニＳｉｇｍａ−Ｔａｕ Ｉｎｄｕｓｔｒｉｅ Ｆａｒｍａｃｅｕｔｉｃｈｅ Ｒｉｕｎｉｔｅ Ｓｏｃｉｅｔａ Ｐｅｒ Ａｚｉｏｎｉ 有痛性末梢糖尿病性神経障害の予防のためのアセチルｌ−カルニチン
IT202200022437A1 (it) 2022-11-02 2024-05-02 Chiesi Italia S P A Composizione farmaceutica comprendente l-acetilcarnitina e beta-cariofillene

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3463261D1 (en) * 1983-12-28 1987-05-27 Sigma Tau Ind Farmaceuti Salts of l-carnitine and alkanoyl l-carnitines and process for preparing same
IT1196564B (it) * 1986-08-04 1988-11-16 Sigma Tau Ind Farmaceuti Impiego di acetil l-carnitina nel trattamento terapeutico delle neuropatie periferiche
IT1277147B1 (it) * 1995-01-20 1997-11-04 Sigma Tau Ind Farmaceuti Uso della carnitina e i suoi derivati per ridurre gli effetti tossici della ciclosporina-a e di altri farmaci immunosoppressivi.

Also Published As

Publication number Publication date
JP2004532865A (ja) 2004-10-28
DE60222662D1 (de) 2007-11-08
SK15842003A3 (sk) 2004-06-08
ITRM20010293A0 (it) 2001-05-29
EP1399141B1 (en) 2007-09-26
WO2002096409A1 (en) 2002-12-05
DK1399141T3 (da) 2008-01-02
US20040152781A1 (en) 2004-08-05
CA2448242C (en) 2011-01-11
HUP0401294A3 (en) 2008-04-28
JP4287660B2 (ja) 2009-07-01
CZ20033220A3 (en) 2004-06-16
PT1399141E (pt) 2007-11-16
PL367616A1 (en) 2005-03-07
KR100873748B1 (ko) 2008-12-12
KR20040003030A (ko) 2004-01-07
ES2290292T3 (es) 2008-02-16
CY1107037T1 (el) 2012-09-26
US20090062388A1 (en) 2009-03-05
ITRM20010293A1 (it) 2002-11-29
CA2448242A1 (en) 2002-12-05
ATE374021T1 (de) 2007-10-15
MXPA03010919A (es) 2004-02-27
HUP0401294A2 (hu) 2004-12-28
SK287559B6 (sk) 2011-02-04
EP1399141A1 (en) 2004-03-24

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Legal Events

Date Code Title Description
8381 Inventor (new situation)

Inventor name: CALVANI, MENOTTI, POMEZIA, IT

Inventor name: MOSCONI, LUIGI, POMEZIA, IT

8364 No opposition during term of opposition