DE60221984T2 - Automatisches flüssigkeitsbehandlungssystem und -verfahren - Google Patents
Automatisches flüssigkeitsbehandlungssystem und -verfahren Download PDFInfo
- Publication number
- DE60221984T2 DE60221984T2 DE60221984T DE60221984T DE60221984T2 DE 60221984 T2 DE60221984 T2 DE 60221984T2 DE 60221984 T DE60221984 T DE 60221984T DE 60221984 T DE60221984 T DE 60221984T DE 60221984 T2 DE60221984 T2 DE 60221984T2
- Authority
- DE
- Germany
- Prior art keywords
- sample
- needle
- injection assembly
- pump
- treatment system
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000007788 liquid Substances 0.000 title claims description 87
- 238000000034 method Methods 0.000 title claims description 49
- 239000012530 fluid Substances 0.000 claims abstract description 113
- 239000000523 sample Substances 0.000 claims description 373
- 238000002347 injection Methods 0.000 claims description 171
- 239000007924 injection Substances 0.000 claims description 171
- 239000003153 chemical reaction reagent Substances 0.000 claims description 50
- 238000004458 analytical method Methods 0.000 claims description 23
- 239000002699 waste material Substances 0.000 claims description 22
- 238000002156 mixing Methods 0.000 claims description 16
- 238000000926 separation method Methods 0.000 claims description 15
- 238000005070 sampling Methods 0.000 claims description 11
- 238000004891 communication Methods 0.000 claims description 8
- 238000007789 sealing Methods 0.000 claims description 8
- 229920000098 polyolefin Polymers 0.000 claims description 5
- 238000012546 transfer Methods 0.000 claims description 5
- KRVSOGSZCMJSLX-UHFFFAOYSA-L chromic acid Substances O[Cr](O)(=O)=O KRVSOGSZCMJSLX-UHFFFAOYSA-L 0.000 claims description 3
- AWJWCTOOIBYHON-UHFFFAOYSA-N furo[3,4-b]pyrazine-5,7-dione Chemical compound C1=CN=C2C(=O)OC(=O)C2=N1 AWJWCTOOIBYHON-UHFFFAOYSA-N 0.000 claims description 3
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- 239000010935 stainless steel Substances 0.000 description 2
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- 101001094044 Mus musculus Solute carrier family 26 member 6 Proteins 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1002—Reagent dispensers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
- G01N15/1409—Handling samples, e.g. injecting samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/38—Diluting, dispersing or mixing samples
- G01N2001/383—Diluting, dispersing or mixing samples collecting and diluting in a flow of liquid
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
- G01N15/1409—Handling samples, e.g. injecting samples
- G01N2015/1411—Features of sheath fluids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1081—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane
- G01N35/109—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane with two horizontal degrees of freedom
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/113332—Automated chemical analysis with conveyance of sample along a test line in a container or rack
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/113332—Automated chemical analysis with conveyance of sample along a test line in a container or rack
- Y10T436/114165—Automated chemical analysis with conveyance of sample along a test line in a container or rack with step of insertion or removal from test line
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/119163—Automated chemical analysis with aspirator of claimed structure
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Landscapes
- Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Dispersion Chemistry (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Control Of Non-Electrical Variables (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29845801P | 2001-06-13 | 2001-06-13 | |
| US298458P | 2001-06-13 | ||
| PCT/US2002/018895 WO2002101360A1 (en) | 2001-06-13 | 2002-06-13 | Automated fluid handling system and method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60221984D1 DE60221984D1 (de) | 2007-10-04 |
| DE60221984T2 true DE60221984T2 (de) | 2008-05-15 |
Family
ID=23150608
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60221984T Expired - Lifetime DE60221984T2 (de) | 2001-06-13 | 2002-06-13 | Automatisches flüssigkeitsbehandlungssystem und -verfahren |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7198956B2 (enExample) |
| EP (1) | EP1399724B1 (enExample) |
| JP (1) | JP2004535572A (enExample) |
| AT (1) | ATE371179T1 (enExample) |
| DE (1) | DE60221984T2 (enExample) |
| WO (1) | WO2002101360A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102011008024B4 (de) * | 2010-02-12 | 2013-11-21 | Riggtek Gmbh Laboratory Instruments | Vorrichtung zur Probenbehandlung |
Families Citing this family (111)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2394161A1 (en) * | 1999-12-24 | 2001-07-05 | Avantium International B.V. | Liquid dispensing device |
| US7420659B1 (en) | 2000-06-02 | 2008-09-02 | Honeywell Interantional Inc. | Flow control system of a cartridge |
| JP2002001092A (ja) * | 2000-06-22 | 2002-01-08 | Shimadzu Corp | 排液装置 |
| JP3665257B2 (ja) * | 2000-07-11 | 2005-06-29 | 株式会社日立製作所 | 分注装置 |
| US6852291B1 (en) * | 2000-10-11 | 2005-02-08 | Innovadyne Technologies, Inc. | Hybrid valve apparatus and method for fluid handling |
| US7135146B2 (en) | 2000-10-11 | 2006-11-14 | Innovadyne Technologies, Inc. | Universal non-contact dispense peripheral apparatus and method for a primary liquid handling device |
| US7198956B2 (en) | 2001-06-13 | 2007-04-03 | Uffenheimer Kenneth F | Automated fluid handling system and method |
| US7384604B2 (en) * | 2001-11-01 | 2008-06-10 | Micromass Uk Limited | Sample introduction system |
| DE60317305T2 (de) * | 2002-01-25 | 2008-08-28 | Innovadyne Technologies, Inc., Santa Rosa | Kontaktloses verfahren zur verteilung geringer flüssigkeitsmengen |
| US7288228B2 (en) * | 2002-02-12 | 2007-10-30 | Gilson, Inc. | Sample injection system |
| AT413002B (de) * | 2002-03-19 | 2005-09-26 | Hoffmann La Roche | Probeneingabevorrichtung für die eingabe medizinischer proben in einen analysator |
| US7951597B2 (en) * | 2002-09-11 | 2011-05-31 | Waters Technologies Corporation | Pressurized fluid sample injector and method of injecting fluid samples |
| US20060153716A1 (en) * | 2002-09-18 | 2006-07-13 | Yoshiyuki Shoji | Device for sucking liquid and method for sucking liquid |
| US20050011582A1 (en) * | 2003-06-06 | 2005-01-20 | Haug Jeffrey S. | Fluid delivery system for a flow cytometer |
| US20050186578A1 (en) * | 2004-02-20 | 2005-08-25 | Sven Bulow | Chamber array arrangement |
| US7101354B2 (en) * | 2004-05-03 | 2006-09-05 | Infusive Technologies, Llc | Mixing syringe with and without flush |
| US6997910B2 (en) * | 2004-05-03 | 2006-02-14 | Infusive Technologies, Llc | Multi-chamber, sequential dose dispensing syringe |
| US7998106B2 (en) * | 2004-05-03 | 2011-08-16 | Thorne Jr Gale H | Safety dispensing system for hazardous substances |
| DE102004024588B4 (de) * | 2004-05-12 | 2007-05-16 | Proteome Factory Ag | Verfahren und Vorrichtung zur Übertragung von Proben aus polymeren Trägermaterialien in Probenaufnahmegefäße |
| EP1766417B1 (en) * | 2004-06-14 | 2013-04-03 | Parker-Hannifin Corporation | Robotic handling system and method with independently operable detachable tools |
| JP4601423B2 (ja) * | 2004-12-28 | 2010-12-22 | 独立行政法人科学技術振興機構 | 細胞計測および分離チップ |
| US7328882B2 (en) | 2005-01-06 | 2008-02-12 | Honeywell International Inc. | Microfluidic modulating valve |
| US7445017B2 (en) | 2005-01-28 | 2008-11-04 | Honeywell International Inc. | Mesovalve modulator |
| EP1849012A2 (en) | 2005-01-28 | 2007-10-31 | Parker-Hannifin Corporation | Sampling probe, gripper and interface for laboratory sample management systems |
| AU2006218816A1 (en) * | 2005-03-01 | 2006-09-08 | Medimmune, Llc | Influenza virus harvester |
| US7517201B2 (en) | 2005-07-14 | 2009-04-14 | Honeywell International Inc. | Asymmetric dual diaphragm pump |
| US20070025879A1 (en) * | 2005-07-27 | 2007-02-01 | Dakocytomation Denmark A/S | Method and apparatus for syringe-based sample introduction within a flow cytometer |
| US7996188B2 (en) | 2005-08-22 | 2011-08-09 | Accuri Cytometers, Inc. | User interface for a flow cytometer system |
| US8017402B2 (en) | 2006-03-08 | 2011-09-13 | Accuri Cytometers, Inc. | Fluidic system for a flow cytometer |
| US8303894B2 (en) | 2005-10-13 | 2012-11-06 | Accuri Cytometers, Inc. | Detection and fluidic system of a flow cytometer |
| US20080314412A1 (en) * | 2005-12-05 | 2008-12-25 | Grippo Paul M | Self-Cleaning Injection Port for Analytical Applications |
| US8283177B2 (en) * | 2006-03-08 | 2012-10-09 | Accuri Cytometers, Inc. | Fluidic system with washing capabilities for a flow cytometer |
| US7780916B2 (en) * | 2006-03-08 | 2010-08-24 | Accuri Cytometers, Inc. | Flow cytometer system with unclogging feature |
| CA2645505A1 (en) * | 2006-03-10 | 2007-09-20 | Mcu Designs, Inc. | High speed sample supply device |
| US8075520B2 (en) * | 2006-04-06 | 2011-12-13 | Reznik Alan M | Arthroscopic fluid control device and method for controlling fluid flow in arthroscopic procedures |
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| US8296088B2 (en) * | 2006-06-02 | 2012-10-23 | Luminex Corporation | Systems and methods for performing measurements of one or more materials |
| US8715573B2 (en) | 2006-10-13 | 2014-05-06 | Accuri Cytometers, Inc. | Fluidic system for a flow cytometer with temporal processing |
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| WO2008140742A1 (en) | 2007-05-08 | 2008-11-20 | Idexx Laboratories, Inc. | Chemical analyzer |
| JP5121333B2 (ja) * | 2007-07-03 | 2013-01-16 | 日立アロカメディカル株式会社 | 分注装置 |
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| CN102483386B (zh) * | 2009-07-01 | 2016-08-17 | 贝克曼考尔特公司 | 用于临床诊断学的改进的离子选择电极模块 |
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| KR101040085B1 (ko) | 2009-09-29 | 2011-06-09 | 아메스산업(주) | 프리믹싱이 가능한 실린지 펌프유닛을 구비한 시약 합성장치 |
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| EP2633284B1 (en) | 2010-10-25 | 2021-08-25 | Accuri Cytometers, Inc. | Systems and user interface for collecting a data set in a flow cytometer |
| US20140290341A1 (en) * | 2011-08-03 | 2014-10-02 | Becton, Dickinson And Company | Detection of a Compromised Flow Line in a Laboratory Instrument |
| DE102011088959B4 (de) | 2011-12-19 | 2022-08-04 | Endress+Hauser Conducta Gmbh+Co. Kg | Vorrichtung zum Entgasen einer Flüssigkeit und Verwendung dieser Vorrichtung in einem Analysegerät |
| JP2013255447A (ja) * | 2012-06-12 | 2013-12-26 | Nippon Koden Corp | 細胞単離装置 |
| CN104520691B (zh) | 2012-06-14 | 2018-02-06 | 生物辐射实验室股份有限公司 | 用于流式细胞术的流动速率平衡、可动态调整的鞘递送系统 |
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- 2002-06-13 DE DE60221984T patent/DE60221984T2/de not_active Expired - Lifetime
- 2002-06-13 JP JP2003504073A patent/JP2004535572A/ja active Pending
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2007
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| DE102011008024B4 (de) * | 2010-02-12 | 2013-11-21 | Riggtek Gmbh Laboratory Instruments | Vorrichtung zur Probenbehandlung |
| DE102011008024B9 (de) * | 2010-02-12 | 2014-03-27 | Riggtek Gmbh | Vorrichtung zur Probenbehandlung |
| US8899101B2 (en) | 2010-02-12 | 2014-12-02 | Riggtek Gmbh | Apparatus for sample handling |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1399724B1 (en) | 2007-08-22 |
| US20020192113A1 (en) | 2002-12-19 |
| WO2002101360A1 (en) | 2002-12-19 |
| ATE371179T1 (de) | 2007-09-15 |
| US7198956B2 (en) | 2007-04-03 |
| EP1399724A1 (en) | 2004-03-24 |
| DE60221984D1 (de) | 2007-10-04 |
| US7939017B2 (en) | 2011-05-10 |
| JP2004535572A (ja) | 2004-11-25 |
| US20070202608A1 (en) | 2007-08-30 |
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