DE60221046T2 - Nachweis von sondenmolekülen, die auf einen aktiven bereich eines sensors gebunden sind - Google Patents

Nachweis von sondenmolekülen, die auf einen aktiven bereich eines sensors gebunden sind Download PDF

Info

Publication number
DE60221046T2
DE60221046T2 DE60221046T DE60221046T DE60221046T2 DE 60221046 T2 DE60221046 T2 DE 60221046T2 DE 60221046 T DE60221046 T DE 60221046T DE 60221046 T DE60221046 T DE 60221046T DE 60221046 T2 DE60221046 T2 DE 60221046T2
Authority
DE
Germany
Prior art keywords
transistors
zone
probe molecules
dna
source
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60221046T
Other languages
German (de)
English (en)
Other versions
DE60221046D1 (de
Inventor
Ulrich Bockelmann
Francois Pouthas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Original Assignee
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27589525&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60221046(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Centre National de la Recherche Scientifique CNRS filed Critical Centre National de la Recherche Scientifique CNRS
Application granted granted Critical
Publication of DE60221046D1 publication Critical patent/DE60221046D1/de
Publication of DE60221046T2 publication Critical patent/DE60221046T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001Enzyme electrodes
    • C12Q1/002Electrode membranes
    • C12Q1/003Functionalisation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Measurement Of Length, Angles, Or The Like Using Electric Or Magnetic Means (AREA)
DE60221046T 2002-01-21 2002-12-11 Nachweis von sondenmolekülen, die auf einen aktiven bereich eines sensors gebunden sind Expired - Lifetime DE60221046T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0200676 2002-01-21
FR0200676A FR2835058B1 (fr) 2002-01-21 2002-01-21 Procede de detection d'au moins un parametre caracteristique de molecules sondes fixees sur au moins une zone active d'un capteur
PCT/FR2002/004283 WO2003062811A1 (fr) 2002-01-21 2002-12-11 Detection de molecules sondes fixees sur une zone active d'un capteur.

Publications (2)

Publication Number Publication Date
DE60221046D1 DE60221046D1 (de) 2007-08-16
DE60221046T2 true DE60221046T2 (de) 2008-03-06

Family

ID=27589525

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60221046T Expired - Lifetime DE60221046T2 (de) 2002-01-21 2002-12-11 Nachweis von sondenmolekülen, die auf einen aktiven bereich eines sensors gebunden sind

Country Status (8)

Country Link
US (1) US7993825B2 (https=)
EP (1) EP1468277B1 (https=)
JP (1) JP4500547B2 (https=)
AT (1) ATE366321T1 (https=)
DE (1) DE60221046T2 (https=)
ES (1) ES2289176T3 (https=)
FR (1) FR2835058B1 (https=)
WO (1) WO2003062811A1 (https=)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005043160A2 (en) * 2003-10-31 2005-05-12 University Of Hawaii Ultrasensitive biochemical sensing platform
US20080009002A1 (en) * 2004-11-09 2008-01-10 The Regents Of The University Of California Analyte Identification Using Electronic Devices
KR100773549B1 (ko) 2006-04-03 2007-11-07 삼성전자주식회사 동일 전계 효과 트랜지스터를 이용하여 생분자를 검출하는방법
KR100773550B1 (ko) 2006-04-03 2007-11-07 삼성전자주식회사 생분자의 고정 없이 전계 효과 트랜지스터를 이용하여생분자를 검출하는 방법
KR101195612B1 (ko) * 2006-04-10 2012-10-29 삼성전자주식회사 금층을 포함하는 전계 효과 트랜지스터, 상기 전계 효과 트랜지스터를 포함하는 미세유동장치, 및 상기 전계 효과 트랜지스터 및 미세유동장치를 이용하여 티올기를 포함하는 분석물을 검출하는 방법
US8349167B2 (en) 2006-12-14 2013-01-08 Life Technologies Corporation Methods and apparatus for detecting molecular interactions using FET arrays
US7948015B2 (en) 2006-12-14 2011-05-24 Life Technologies Corporation Methods and apparatus for measuring analytes using large scale FET arrays
US8262900B2 (en) 2006-12-14 2012-09-11 Life Technologies Corporation Methods and apparatus for measuring analytes using large scale FET arrays
US11339430B2 (en) 2007-07-10 2022-05-24 Life Technologies Corporation Methods and apparatus for measuring analytes using large scale FET arrays
US8198658B2 (en) * 2007-06-13 2012-06-12 Samsung Electronics Co., Ltd. Device and method for detecting biomolecules using adsorptive medium and field effect transistor
KR101375547B1 (ko) * 2007-06-19 2014-03-25 삼성전자주식회사 표준 전극이 포함된 전계 효과 트랜지스터 어레이를 이용한생체 분자의 검출 장치 및 방법
US20100137143A1 (en) 2008-10-22 2010-06-03 Ion Torrent Systems Incorporated Methods and apparatus for measuring analytes
US20100301398A1 (en) 2009-05-29 2010-12-02 Ion Torrent Systems Incorporated Methods and apparatus for measuring analytes
US20120261274A1 (en) 2009-05-29 2012-10-18 Life Technologies Corporation Methods and apparatus for measuring analytes
US8776573B2 (en) 2009-05-29 2014-07-15 Life Technologies Corporation Methods and apparatus for measuring analytes
AU2011226767B1 (en) 2010-06-30 2011-11-10 Life Technologies Corporation Ion-sensing charge-accumulation circuits and methods
US8487790B2 (en) 2010-06-30 2013-07-16 Life Technologies Corporation Chemical detection circuit including a serializer circuit
EP2588850B1 (en) 2010-06-30 2016-12-28 Life Technologies Corporation Method for dry testing isfet arrays
US11307166B2 (en) 2010-07-01 2022-04-19 Life Technologies Corporation Column ADC
CN103168341B (zh) 2010-07-03 2016-10-05 生命科技公司 具有轻度掺杂的排出装置的化学敏感的传感器
EP2617061B1 (en) 2010-09-15 2021-06-30 Life Technologies Corporation Methods and apparatus for measuring analytes
US9970984B2 (en) 2011-12-01 2018-05-15 Life Technologies Corporation Method and apparatus for identifying defects in a chemical sensor array
US8786331B2 (en) 2012-05-29 2014-07-22 Life Technologies Corporation System for reducing noise in a chemical sensor array
US9080968B2 (en) 2013-01-04 2015-07-14 Life Technologies Corporation Methods and systems for point of use removal of sacrificial material
US9841398B2 (en) 2013-01-08 2017-12-12 Life Technologies Corporation Methods for manufacturing well structures for low-noise chemical sensors
US8963216B2 (en) 2013-03-13 2015-02-24 Life Technologies Corporation Chemical sensor with sidewall spacer sensor surface
US20140264471A1 (en) 2013-03-15 2014-09-18 Life Technologies Corporation Chemical device with thin conductive element
CN105264366B (zh) 2013-03-15 2019-04-16 生命科技公司 具有一致传感器表面区域的化学传感器
US9835585B2 (en) 2013-03-15 2017-12-05 Life Technologies Corporation Chemical sensor with protruded sensor surface
US20140336063A1 (en) 2013-05-09 2014-11-13 Life Technologies Corporation Windowed Sequencing
US10458942B2 (en) 2013-06-10 2019-10-29 Life Technologies Corporation Chemical sensor array having multiple sensors per well
CN111505087A (zh) 2014-12-18 2020-08-07 生命科技公司 使用大规模 fet 阵列测量分析物的方法和装置
EP3234576B1 (en) 2014-12-18 2023-11-22 Life Technologies Corporation High data rate integrated circuit with transmitter configuration
US10077472B2 (en) 2014-12-18 2018-09-18 Life Technologies Corporation High data rate integrated circuit with power management
US11293897B2 (en) * 2018-11-30 2022-04-05 Taiwan Semiconductor Manufacturing Company, Ltd. High sensitivity ISFET sensor
GB202017861D0 (en) 2020-11-12 2020-12-30 Ulifetec Sas Method

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4238757A (en) * 1976-03-19 1980-12-09 General Electric Company Field effect transistor for detection of biological reactions
EP0213825A3 (en) * 1985-08-22 1989-04-26 Molecular Devices Corporation Multiple chemically modulated capacitance
US5200051A (en) * 1988-11-14 1993-04-06 I-Stat Corporation Wholly microfabricated biosensors and process for the manufacture and use thereof
US5242793A (en) * 1989-03-08 1993-09-07 Kanzaki Paper Manufacturing Co., Ltd. Selective permeable membrane and electrode using the same
US5498521A (en) * 1990-01-24 1996-03-12 President And Fellows Of Harvard College Diagnosis of hereditary retinal degenerative diseases
AU2907092A (en) * 1991-10-21 1993-05-21 James W. Holm-Kennedy Method and device for biochemical sensing
US5846708A (en) * 1991-11-19 1998-12-08 Massachusetts Institiute Of Technology Optical and electrical methods and apparatus for molecule detection
ATE198358T1 (de) * 1992-04-27 2001-01-15 Dartmouth College Detektion von gensequenzen in biologischen flüssigkeiten
US6331274B1 (en) * 1993-11-01 2001-12-18 Nanogen, Inc. Advanced active circuits and devices for molecular biological analysis and diagnostics
US5856174A (en) * 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
US5805014A (en) * 1996-03-01 1998-09-08 Compaq Computer Corporation System having active pull-down circuit and method
EP0894148A4 (en) * 1996-04-17 1999-06-16 Motorola Inc MOLECULAR DETECTION, APPARATUS AND METHOD WITH INTEGRATED TRANSISTOR
US5827482A (en) * 1996-08-20 1998-10-27 Motorola Corporation Transistor-based apparatus and method for molecular detection and field enhancement
US6322963B1 (en) * 1998-06-15 2001-11-27 Biosensor Systems Design., Inc. Sensor for analyte detection
US6281006B1 (en) * 1998-08-24 2001-08-28 Therasense, Inc. Electrochemical affinity assay
US6875619B2 (en) * 1999-11-12 2005-04-05 Motorola, Inc. Microfluidic devices comprising biochannels
FR2805826B1 (fr) * 2000-03-01 2002-09-20 Nucleica Nouvelles puces a adn
EP1134294A3 (en) * 2000-03-16 2004-06-30 Kabushiki Kaisha Toshiba Method for producing immobilized nucleic acid strand
WO2003014722A1 (en) * 2001-08-08 2003-02-20 The Arizona Board Of Regents Nucleic acid field effect transistor
DE60127469T2 (de) * 2001-12-19 2007-12-06 Hitachi High-Technologies Corp. Potentiometrischer dna-mikroarray, verfahren zu dessen herstellung und verfahren zur nukleinsäureanalyse
WO2004057027A1 (fr) * 2002-12-11 2004-07-08 Centre National De La Recherche Scientifique Procede de detection electronique d'au moins une interaction specifique entre des molecules sondes et des biomolecules cibles.

Also Published As

Publication number Publication date
WO2003062811A1 (fr) 2003-07-31
EP1468277B1 (fr) 2007-07-04
FR2835058B1 (fr) 2004-03-12
ES2289176T3 (es) 2008-02-01
ATE366321T1 (de) 2007-07-15
JP4500547B2 (ja) 2010-07-14
JP2005515475A (ja) 2005-05-26
FR2835058A1 (fr) 2003-07-25
EP1468277A1 (fr) 2004-10-20
US7993825B2 (en) 2011-08-09
DE60221046D1 (de) 2007-08-16
US20060011911A1 (en) 2006-01-19

Similar Documents

Publication Publication Date Title
DE60221046T2 (de) Nachweis von sondenmolekülen, die auf einen aktiven bereich eines sensors gebunden sind
DE60127469T2 (de) Potentiometrischer dna-mikroarray, verfahren zu dessen herstellung und verfahren zur nukleinsäureanalyse
DE602005001367T2 (de) Vorrichtung und Verfahren zur Vermessung biologischen Materials
EP1516175B1 (de) Biosensor-array und verfahren zum betreiben eines biosensor-arrays
DE10255755B4 (de) Integrierte elektronische Schaltung mit Feldeffekt-Sensoren zum Nachweis von Biomolekülen
DE112005000293B4 (de) Verfahren zum Analysieren einer Genpolymorphie
DE10163557B4 (de) Transistorbasierter Sensor mit besonders ausgestalteter Gateelektrode zur hochempfindlichen Detektion von Analyten
EP1786927B1 (de) Vorrichtung und verfahren zum nachweis von geladenen makromolekülen
JP2005515475A6 (ja) センサーの反応性ゾーンに固定された分子プローブの検出
DE10221799A1 (de) Silicon-on-Insulator-Biosensor
DE3513168A1 (de) Biosensor bestehend aus einem halbleiter auf silizium oder kohlenstoffbasis (elektronischer teil) und nukleinbasen (od. anderen biol. monomeren)
DE10324912A1 (de) Verfahren zur Detektion von DNA-Punktmutationen (SNP-Analyse) sowie zugehörige Anordnung
US7908088B2 (en) Method for electronically detecting at least one specific interaction between probe molecules and target biomolecules
DE10163599B4 (de) Verfahren zur Bestimmung von Nukleinsäureanalyten
DE10311315A1 (de) Verfahren und Vorrichtung zur Detektion von Biomolekülen
EP1444357B1 (de) Verfahren zum erfassen von nukleinsäuremolekülen mittels mindestens einer einheit zum immobilisieren von nukleinsäuremolekülen und biosensor zum erfassen von nukleinsäuremolekülen
WO2005008234A1 (de) Sensor-transistor-element, sensor-einheit und sensor-array
EP1761761A1 (de) Vorrichtung und verfahren zur emulation einer gegenelektrode in einem monolithisch integrierten elektrochemischen analysesystem
WO2005116244A1 (de) Sensor-anordnung mit electrode zur erfassung von diffundierenden geladenen teilchen
DE19960398B4 (de) Verfahren und elektrochemischer Sensor mit geheizten Elektroden für die biochemische Analytik, insbesondere zur Untersuchung von Hybridisierungsvorgängen der Nucleinsäuren
DE10220935B3 (de) Verfahren für die biochemische Analytik von DNA und zugehörige Anordnung
WO2003083134A1 (de) Sensor zur qualitativen und quantitativen bestimmung von (bio)organischen oligomeren und polymeren, analyseverfahren hierzu sowie verfahren zur herstellung des sensors
DE10256415B3 (de) Verfahren und Vorrichtung zum Transport bzw. zur bindungspezifischen Trennung elektrisch geladener Moleküle
EP1255982B1 (de) Messverfahren unter einsatz mindestens einer biologischen rezeptorzelle sowie eine zur durchführung des messverfahrens geeignete vorrichtung
EP1200817B1 (de) Sensoranordnung mit elektrisch ansteuerbaren arrays

Legal Events

Date Code Title Description
8364 No opposition during term of opposition