DE60220436D1 - Microkügelchen mit einem pleuromutilin-derivat - Google Patents

Microkügelchen mit einem pleuromutilin-derivat

Info

Publication number
DE60220436D1
DE60220436D1 DE60220436T DE60220436T DE60220436D1 DE 60220436 D1 DE60220436 D1 DE 60220436D1 DE 60220436 T DE60220436 T DE 60220436T DE 60220436 T DE60220436 T DE 60220436T DE 60220436 D1 DE60220436 D1 DE 60220436D1
Authority
DE
Germany
Prior art keywords
pleuromutiline
derivative
micro bearing
micro
bearing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60220436T
Other languages
English (en)
Other versions
DE60220436T2 (de
Inventor
Susanne Chr Wieland-Berghausen
Ferenc Jozsef Rakoczi
Brigitte Monika Cron-Eckhardt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of DE60220436D1 publication Critical patent/DE60220436D1/de
Application granted granted Critical
Publication of DE60220436T2 publication Critical patent/DE60220436T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/195—Antibiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K40/00—Shaping or working-up of animal feeding-stuffs
    • A23K40/20—Shaping or working-up of animal feeding-stuffs by moulding, e.g. making cakes or briquettes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K40/00—Shaping or working-up of animal feeding-stuffs
    • A23K40/25—Shaping or working-up of animal feeding-stuffs by extrusion
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K40/00—Shaping or working-up of animal feeding-stuffs
    • A23K40/30—Shaping or working-up of animal feeding-stuffs by encapsulating; by coating
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/60—Feeding-stuffs specially adapted for particular animals for weanlings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Husbandry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Fodder In General (AREA)
  • Medicinal Preparation (AREA)
DE60220436T 2001-11-28 2002-11-27 Microkügelchen mit einem pleuromutilin-derivat Expired - Lifetime DE60220436T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP01128276 2001-11-28
EP01128276 2001-11-28
PCT/EP2002/013388 WO2003045354A1 (en) 2001-11-28 2002-11-27 Micropherules containing a pleuromutilin derivative

Publications (2)

Publication Number Publication Date
DE60220436D1 true DE60220436D1 (de) 2007-07-12
DE60220436T2 DE60220436T2 (de) 2008-01-31

Family

ID=8179384

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60220436T Expired - Lifetime DE60220436T2 (de) 2001-11-28 2002-11-27 Microkügelchen mit einem pleuromutilin-derivat

Country Status (21)

Country Link
US (1) US8236851B2 (de)
EP (1) EP1450767B1 (de)
JP (1) JP4537708B2 (de)
KR (1) KR100965017B1 (de)
CN (1) CN100348185C (de)
AR (1) AR038367A1 (de)
AT (1) ATE363270T1 (de)
AU (1) AU2002356740B2 (de)
BR (1) BR0214521B1 (de)
CA (1) CA2466671C (de)
CO (1) CO5390081A1 (de)
CY (1) CY1106745T1 (de)
DE (1) DE60220436T2 (de)
DK (1) DK1450767T3 (de)
ES (1) ES2284980T3 (de)
MX (1) MXPA04005186A (de)
NZ (1) NZ533085A (de)
PT (1) PT1450767E (de)
RU (1) RU2296004C2 (de)
WO (1) WO2003045354A1 (de)
ZA (1) ZA200403801B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101690717B (zh) * 2009-09-30 2013-03-06 北京大北农动物保健科技有限责任公司 一种兽用沃尼妙林及其盐的预混剂及制备方法
US20110269657A1 (en) * 2010-04-28 2011-11-03 Jiten Odhavji Dihora Delivery particles
CZ308210B6 (cs) * 2011-11-02 2020-03-04 Veterinární A Farmaceutická Univerzita Brno Farmaceutická kompozice ve formě pelet majících velikost částic v rozmezí od 0,1 do 10 mm pro perorální podání vodním živočichům a způsob její výroby
CN102512376A (zh) * 2011-11-29 2012-06-27 河南牧翔动物药业有限公司 一种沃尼妙林凝胶微球及其制备方法
CN102579364B (zh) * 2012-03-05 2013-10-09 河北科技大学 沃尼妙林/沃尼妙林盐的缓控释微球及其制备方法
CN103948567B (zh) * 2014-04-17 2015-10-14 江苏省家禽科学研究所 一种泰妙菌素微囊制剂的制备方法
CN108926536A (zh) * 2017-05-22 2018-12-04 北京科百大科技有限责任公司 一种稳定的盐酸沃尼妙林组合物的制备方法
CN108484424A (zh) * 2018-04-08 2018-09-04 中国农业科学院兰州畜牧与兽药研究所 侧链含有季铵盐基团的截短侧耳素类衍生物及其用途
KR102098289B1 (ko) * 2018-04-11 2020-04-07 경북대학교 산학협력단 발네물린을 유효성분으로 함유하는 골 질환 예방 또는 치료용 조성물

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA923384A (en) * 1970-02-03 1973-03-27 Abe Jinnosuke Process for preparing a micro capsule
US3919290A (en) * 1972-10-03 1975-11-11 Sandoz Ltd Substituted 14-desoxy-mutilins
US3987194A (en) * 1975-05-12 1976-10-19 E. R. Squibb & Sons, Inc. Use of pleuromutilin derivatives for the treatment of swine dysentery
US4086359A (en) * 1975-09-30 1978-04-25 E. R. Squibb & Sons, Inc. Derivatives of pleuromutilin and compositions
JPS58148816A (ja) * 1982-02-27 1983-09-05 Nippon Zenyaku Kogyo Kk 低刺激性チアムリン注射剤
DE3560511D1 (en) 1984-02-17 1987-10-01 Sandoz Ag Pleuromutilin derivatives, process for their preparation and their use
DE3422782A1 (de) * 1984-06-20 1986-01-02 Boehringer Ingelheim Vetmedica GmbH, 6507 Ingelheim Zinkbacitracin enthaltender futtermittelzusatz
JPH072638B2 (ja) * 1986-07-28 1995-01-18 日本化薬株式会社 経口投与用製剤
US5460817A (en) * 1988-01-19 1995-10-24 Allied Colloids Ltd. Particulate composition comprising a core of matrix polymer with active ingredient distributed therein
JP2854034B2 (ja) * 1989-09-13 1999-02-03 ノバルティス アクチエンゲゼルシャフト 粒状動物用医薬組成物
JPH041132A (ja) * 1990-04-18 1992-01-06 Sds Biotech Kk 魚類の細菌性疾患の予防・治療剤
AT400674B (de) * 1991-07-24 1996-02-26 Biochemie Gmbh Pharmazeutische pleuromutilin-zubereitung
DE4308282C2 (de) * 1993-03-16 1994-12-22 Beiersdorf Ag Vorzugsweise in Form von Mikrosphärulen vorliegende galenische Matrices
IT1265290B1 (it) * 1993-12-17 1996-10-31 Dox Al Italia Spa Miscele ad elevato contenuto di sostanze attive idonee ad essere distribuite in modo omogeneo nei mangimi per animali.
GB9406094D0 (en) * 1994-03-28 1994-05-18 Univ Nottingham And University Polymer microspheres and a method of production thereof
ATE228773T1 (de) * 1994-10-20 2002-12-15 Chevita Tierarzneimittel Ges M Verfahren zur herstellung von futtermitteln, die pharmakologisch wirksame substanzen enthalten
US5614222A (en) * 1994-10-25 1997-03-25 Kaplan; Milton R. Stable aqueous drug suspensions and methods for preparation thereof
GB9500863D0 (en) * 1995-01-17 1995-03-08 Grampian Pharm Ltd Medicated animal foodstuffs
US5607697A (en) * 1995-06-07 1997-03-04 Cima Labs, Incorporated Taste masking microparticles for oral dosage forms
KR100516418B1 (ko) * 1996-07-04 2005-12-20 바이오케미 게젤샤프트 엠베하 플루로뮤틸린유도체의수의학적용도
GB9614017D0 (en) 1996-07-04 1996-09-04 Biochemie Gmbh Organic compounds
KR100302314B1 (ko) * 1998-05-12 2002-04-24 김종인 세파클로르의서방성매트릭스제형
TWI260220B (en) 1999-11-22 2006-08-21 Novartis Ag A pharmaceutical composition for the transdermal treatment of bacterial infections in animals
TWI228048B (en) * 1999-12-09 2005-02-21 Novartis Ag New formulation

Also Published As

Publication number Publication date
BR0214521A (pt) 2004-10-26
DE60220436T2 (de) 2008-01-31
EP1450767A1 (de) 2004-09-01
AR038367A1 (es) 2005-01-12
AU2002356740B2 (en) 2006-06-15
JP2005523243A (ja) 2005-08-04
EP1450767B1 (de) 2007-05-30
BR0214521B1 (pt) 2014-05-27
CA2466671A1 (en) 2003-06-05
RU2296004C2 (ru) 2007-03-27
ES2284980T3 (es) 2007-11-16
CN1592608A (zh) 2005-03-09
RU2004119815A (ru) 2006-01-10
AU2002356740A1 (en) 2003-06-10
KR20040058334A (ko) 2004-07-03
ZA200403801B (en) 2006-05-31
PT1450767E (pt) 2007-09-05
DK1450767T3 (da) 2007-08-13
MXPA04005186A (es) 2004-08-11
ATE363270T1 (de) 2007-06-15
US8236851B2 (en) 2012-08-07
WO2003045354A1 (en) 2003-06-05
KR100965017B1 (ko) 2010-06-21
JP4537708B2 (ja) 2010-09-08
CN100348185C (zh) 2007-11-14
CA2466671C (en) 2011-03-29
NZ533085A (en) 2005-10-28
WO2003045354A8 (en) 2004-08-26
CY1106745T1 (el) 2012-05-23
US20050070486A1 (en) 2005-03-31
CO5390081A1 (es) 2004-04-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC