DE60211303D1 - Verfahren zur herstellung und zwischenprodukte von pyridin-2-yl-amin - Google Patents

Verfahren zur herstellung und zwischenprodukte von pyridin-2-yl-amin

Info

Publication number
DE60211303D1
DE60211303D1 DE60211303T DE60211303T DE60211303D1 DE 60211303 D1 DE60211303 D1 DE 60211303D1 DE 60211303 T DE60211303 T DE 60211303T DE 60211303 T DE60211303 T DE 60211303T DE 60211303 D1 DE60211303 D1 DE 60211303D1
Authority
DE
Germany
Prior art keywords
pyridin
amine
preparation
intermediate products
cyanohydrins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60211303T
Other languages
English (en)
Other versions
DE60211303T2 (de
Inventor
Jean-Louis Maurel
Bernard Bonnaud
Jean-Paul Ribet
Bernard Vacher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Application granted granted Critical
Publication of DE60211303D1 publication Critical patent/DE60211303D1/de
Publication of DE60211303T2 publication Critical patent/DE60211303T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/38Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DE60211303T 2001-02-09 2002-02-11 Verfahren zur herstellung und zwischenprodukte von pyridin-2-yl-amin Expired - Lifetime DE60211303T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0101784 2001-02-09
FR0101784A FR2820743B1 (fr) 2001-02-09 2001-02-09 Procede et intermediaires de synthese pour la preparation de derives de pyridin-2-yl-methylamine
PCT/FR2002/000508 WO2002064585A1 (fr) 2001-02-09 2002-02-11 Procede de synthese et intermediaires de pyridin-2-yl-methylamine

Publications (2)

Publication Number Publication Date
DE60211303D1 true DE60211303D1 (de) 2006-06-14
DE60211303T2 DE60211303T2 (de) 2007-04-26

Family

ID=8859834

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60211303T Expired - Lifetime DE60211303T2 (de) 2001-02-09 2002-02-11 Verfahren zur herstellung und zwischenprodukte von pyridin-2-yl-amin

Country Status (12)

Country Link
US (1) US7208603B2 (de)
EP (1) EP1358179B1 (de)
JP (1) JP4259113B2 (de)
AT (1) ATE325794T1 (de)
CA (1) CA2437813C (de)
CY (1) CY1105526T1 (de)
DE (1) DE60211303T2 (de)
DK (1) DK1358179T3 (de)
ES (1) ES2263769T3 (de)
FR (1) FR2820743B1 (de)
PT (1) PT1358179E (de)
WO (1) WO2002064585A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2840900B1 (fr) * 2002-06-18 2005-02-25 Pf Medicament Nouveaux derives d'aryl[4-halogeno-4- [(heteroaryl-methylamino)-methyl]-piperidin-1-yl]-methanone, leur procede de preparation et leur utilisation a titre de medicaments
FR2891274B1 (fr) 2005-09-27 2007-11-23 Pierre Fabre Medicament Sa Procede de preparation du (3-chloro-4-fluoro-phenyl)-(4- fluoro-4-{[(5-methyl-pyrimidin-2-ylmethyl)-amino]-methyl}- piperidin-1-yl)-methanone et nouveaux derives pyrimidiniques intermediaires.
JP2011520975A (ja) * 2008-05-19 2011-07-21 ユニヴァーシティ オブ テネシー リサーチ ファウンデーション,ザ ピリミジンの非古典的カンナビノイド化合物及び関連する使用方法
US8389534B2 (en) * 2008-05-19 2013-03-05 The University Of Tennessee Research Foundation Pyrimidine non-classical cannabinoid compounds and related methods of use
US10548885B2 (en) 2014-07-09 2020-02-04 Pierre Fabre Medicament Method for treating movement disorders with befiradol
CN105566214B (zh) * 2014-10-17 2020-05-15 上海医药工业研究院 3-[2-(3-氯苯基)乙基]-2-吡啶甲酸的制备工艺
US10626105B2 (en) 2016-09-22 2020-04-21 Auspex Pharmaceuticals, Inc. Deuterium-substituted pyridin- and pyrimidin-2-yl-methylamine compounds
JP7401395B2 (ja) 2020-05-29 2023-12-19 ローム株式会社 基準電圧生成回路

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4482437A (en) * 1984-04-05 1984-11-13 Reilly Tar & Chemical Corp. Electrochemical reductions of cyanopyridine bases
KR19990076876A (ko) * 1995-12-29 1999-10-25 스티븐 베네티아너 비트로넥틴 수용체 길항제
AU3461497A (en) * 1996-07-17 1998-02-09 Nippon Kayaku Kabushiki Kaisha Novel nitrogen monoxide synthetase inhibitors
FR2755967B1 (fr) * 1996-11-21 1999-01-29 Pf Medicament Derives de la pyridin-2-yl-methylamine, leur procede de preparation et leur application comme medicaments

Also Published As

Publication number Publication date
WO2002064585A1 (fr) 2002-08-22
EP1358179A1 (de) 2003-11-05
DE60211303T2 (de) 2007-04-26
PT1358179E (pt) 2006-09-29
FR2820743B1 (fr) 2005-02-25
JP4259113B2 (ja) 2009-04-30
CA2437813A1 (fr) 2002-08-22
CY1105526T1 (el) 2010-07-28
US20040116705A1 (en) 2004-06-17
DK1358179T3 (da) 2006-09-11
US7208603B2 (en) 2007-04-24
ATE325794T1 (de) 2006-06-15
EP1358179B1 (de) 2006-05-10
FR2820743A1 (fr) 2002-08-16
JP2004519472A (ja) 2004-07-02
ES2263769T3 (es) 2006-12-16
CA2437813C (fr) 2011-04-19

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition