DE602006018911D1 - Organische Polymerpartikel und Herstellungsverfahren dafür, magnetische Partikel zur Diagnose, Partikel mit einer Carboxylgruppe und Herstellungsverfahren dafür sowie sondengebundene Partikel und Herstellungsverfahren dafür - Google Patents

Organische Polymerpartikel und Herstellungsverfahren dafür, magnetische Partikel zur Diagnose, Partikel mit einer Carboxylgruppe und Herstellungsverfahren dafür sowie sondengebundene Partikel und Herstellungsverfahren dafür

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Publication number
DE602006018911D1
DE602006018911D1 DE602006018911T DE602006018911T DE602006018911D1 DE 602006018911 D1 DE602006018911 D1 DE 602006018911D1 DE 602006018911 T DE602006018911 T DE 602006018911T DE 602006018911 T DE602006018911 T DE 602006018911T DE 602006018911 D1 DE602006018911 D1 DE 602006018911D1
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Germany
Prior art keywords
particles
methods
preparation
therefor
diagnosis
Prior art date
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Active
Application number
DE602006018911T
Other languages
English (en)
Inventor
Kouji Tamori
Tetsuo Fukuta
Mitsuhiro Murata
Masaru Ueno
Satoshi Katayose
Eiji Takamoto
Kiyoshi Kasai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
JSR Corp
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JSR Corp
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37496749&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE602006018911(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from JP2005318065A external-priority patent/JP4687891B2/ja
Priority claimed from JP2006048947A external-priority patent/JP4984025B2/ja
Priority claimed from JP2006076085A external-priority patent/JP4803366B2/ja
Priority claimed from JP2006085040A external-priority patent/JP4985916B2/ja
Application filed by JSR Corp filed Critical JSR Corp
Publication of DE602006018911D1 publication Critical patent/DE602006018911D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/26—Esters containing oxygen in addition to the carboxy oxygen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/26—Esters containing oxygen in addition to the carboxy oxygen
    • C08F220/32—Esters containing oxygen in addition to the carboxy oxygen containing epoxy radicals
    • C08F220/325—Esters containing oxygen in addition to the carboxy oxygen containing epoxy radicals containing glycidyl radical, e.g. glycidyl (meth)acrylate
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F257/00—Macromolecular compounds obtained by polymerising monomers on to polymers of aromatic monomers as defined in group C08F12/00
    • C08F257/02—Macromolecular compounds obtained by polymerising monomers on to polymers of aromatic monomers as defined in group C08F12/00 on to polymers of styrene or alkyl-substituted styrenes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F265/00—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00
    • C08F265/04—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00 on to polymers of esters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F291/00—Macromolecular compounds obtained by polymerising monomers on to macromolecular compounds according to more than one of the groups C08F251/00 - C08F289/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/34—Introducing sulfur atoms or sulfur-containing groups
    • C08F8/36—Sulfonation; Sulfation
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/42—Introducing metal atoms or metal-containing groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/44—Preparation of metal salts or ammonium salts
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L33/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • C08L33/04—Homopolymers or copolymers of esters
    • C08L33/06—Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, which oxygen atoms are present only as part of the carboxyl radical
    • C08L33/062—Copolymers with monomers not covered by C08L33/06
    • C08L33/066—Copolymers with monomers not covered by C08L33/06 containing -OH groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L51/00—Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
    • C08L51/003—Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers grafted on to macromolecular compounds obtained by reactions only involving unsaturated carbon-to-carbon bonds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/5434—Magnetic particles using magnetic particle immunoreagent carriers which constitute new materials per se
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F1/00—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
    • H01F1/0036—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties showing low dimensional magnetism, i.e. spin rearrangements due to a restriction of dimensions, e.g. showing giant magnetoresistivity
    • H01F1/0045—Zero dimensional, e.g. nanoparticles, soft nanoparticles for medical/biological use
    • H01F1/0054—Coated nanoparticles, e.g. nanoparticles coated with organic surfactant
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/10—Esters
    • C08F222/1006—Esters of polyhydric alcohols or polyhydric phenols
    • C08F222/102—Esters of polyhydric alcohols or polyhydric phenols of dialcohols, e.g. ethylene glycol di(meth)acrylate or 1,4-butanediol dimethacrylate
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/10—Esters
    • C08F222/1006—Esters of polyhydric alcohols or polyhydric phenols
    • C08F222/103—Esters of polyhydric alcohols or polyhydric phenols of trialcohols, e.g. trimethylolpropane tri(meth)acrylate
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2810/00—Chemical modification of a polymer
    • C08F2810/20—Chemical modification of a polymer leading to a crosslinking, either explicitly or inherently
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L25/00—Compositions of, homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring; Compositions of derivatives of such polymers
    • C08L25/02—Homopolymers or copolymers of hydrocarbons
    • C08L25/04—Homopolymers or copolymers of styrene
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y10T428/2998—Coated including synthetic resin or polymer

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Nanotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Power Engineering (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
DE602006018911T 2005-11-01 2006-10-12 Organische Polymerpartikel und Herstellungsverfahren dafür, magnetische Partikel zur Diagnose, Partikel mit einer Carboxylgruppe und Herstellungsverfahren dafür sowie sondengebundene Partikel und Herstellungsverfahren dafür Active DE602006018911D1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2005318065A JP4687891B2 (ja) 2005-11-01 2005-11-01 診断薬用磁性粒子
JP2006015994 2006-01-25
JP2006048947A JP4984025B2 (ja) 2006-01-25 2006-02-24 有機ポリマー粒子およびその製造方法、ならびにプローブ結合粒子
JP2006076085A JP4803366B2 (ja) 2006-03-20 2006-03-20 有機ポリマー粒子およびその製造方法、プローブ結合用有機ポリマー粒子およびその製造方法、ならびにプローブ結合粒子およびその製造方法
JP2006085040A JP4985916B2 (ja) 2006-03-27 2006-03-27 カルボキシル基含有粒子の製造方法

Publications (1)

Publication Number Publication Date
DE602006018911D1 true DE602006018911D1 (de) 2011-01-27

Family

ID=37496749

Family Applications (3)

Application Number Title Priority Date Filing Date
DE602006010956T Active DE602006010956D1 (de) 2005-11-01 2006-10-12 Magnetische Partikel für die Diagnostik
DE602006018911T Active DE602006018911D1 (de) 2005-11-01 2006-10-12 Organische Polymerpartikel und Herstellungsverfahren dafür, magnetische Partikel zur Diagnose, Partikel mit einer Carboxylgruppe und Herstellungsverfahren dafür sowie sondengebundene Partikel und Herstellungsverfahren dafür
DE602006012040T Active DE602006012040D1 (de) 2005-11-01 2006-10-12 Organische Polymerpartikel und Herstellungsverfahren dafür, magnetische Partikel zur Diagnose, Partikel mit einer Carboxylgruppe und Herstellungsverfahren dafür sowie sondengebundene Partikel und Herstellungsverfahren dafür

Family Applications Before (1)

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DE602006010956T Active DE602006010956D1 (de) 2005-11-01 2006-10-12 Magnetische Partikel für die Diagnostik

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE602006012040T Active DE602006012040D1 (de) 2005-11-01 2006-10-12 Organische Polymerpartikel und Herstellungsverfahren dafür, magnetische Partikel zur Diagnose, Partikel mit einer Carboxylgruppe und Herstellungsverfahren dafür sowie sondengebundene Partikel und Herstellungsverfahren dafür

Country Status (3)

Country Link
US (1) US8703289B2 (de)
EP (3) EP1890147B1 (de)
DE (3) DE602006010956D1 (de)

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DE602006010956D1 (de) * 2005-11-01 2010-01-21 Jsr Corp Magnetische Partikel für die Diagnostik
JP4716034B2 (ja) 2006-03-24 2011-07-06 Ｊｓｒ株式会社 磁性粒子およびその製造方法
JP4840580B2 (ja) * 2006-07-26 2011-12-21 Ｊｓｒ株式会社 磁性粒子およびその製造方法、ならびにプローブ結合粒子
JP5003868B2 (ja) * 2006-09-28 2012-08-15 Ｊｓｒ株式会社 有機ポリマー粒子およびその製造方法
EP1936372A1 (de) * 2006-12-14 2008-06-25 JSR Corporation Nichtspezifischer Adsorptionshemmer, sondengebundene Partikel und Herstellungsverfahren dafür
BRPI0809138B8 (pt) * 2007-03-20 2021-07-27 Becton Dickinson Co método para detectar a presença ou quantidade de um ou mais analitos em uma amostra biológica
US8859699B2 (en) * 2007-05-30 2014-10-14 Jsr Corporation Non-specific adsorption inhibitor
JP2010260877A (ja) * 2007-08-29 2010-11-18 Jsr Corp 有機ポリマー粒子およびプローブ結合粒子
WO2010147146A1 (ja) * 2009-06-16 2010-12-23 Jsr株式会社 標的細胞の検出方法
WO2013133258A1 (ja) * 2012-03-06 2013-09-12 Jsr株式会社 抗体精製方法および抗体精製用の担体
CA2882806C (en) 2012-08-30 2020-07-21 Weiguo ZHAO Polymer beads incorporating solid particulate material
KR101931418B1 (ko) 2013-10-29 2018-12-20 가부시키가이샤 오사카소다 전지 전극용 바인더, 및 그것을 사용한 전극 그리고 전지
EP3115384B1 (de) 2014-03-05 2020-07-29 JSR Corporation Fester träger, ligandengebundener fester träger, verfahren zur erkennung oder trennung für die zielsubstanz, verfahren zur herstellung des festen trägers und verfahren zur herstellung des ligandengebundenen festen trägers
KR102300483B1 (ko) 2017-04-06 2021-09-10 아사히 가세이 가부시키가이샤 친수화 착색 셀룰로오스 미립자
EP3770191A4 (de) * 2018-04-27 2021-11-10 Canon Kabushiki Kaisha Teilchen, verfahren zur herstellung von teilchen, affinitätsteilchen, reagens und kit damit sowie verfahren zum nachweis einer zielsubstanz
CN109749029B (zh) * 2019-01-02 2021-06-18 兰州理工大学 一种高分子聚合物及其制备方法及应用
EP4023682A4 (de) * 2019-08-30 2023-11-08 Canon Kabushiki Kaisha Partikel, affinitätspartikel mit ligand für zielsubstanz, in-vitro-diagnostisches reagenz und kit damit und verfahren zum nachweis einer zielsubstanz
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US8703289B2 (en) 2014-04-22
EP1780544A1 (de) 2007-05-02
EP1890147B1 (de) 2010-01-27
EP1780544B1 (de) 2009-12-09
US20070099814A1 (en) 2007-05-03
EP1890148A1 (de) 2008-02-20
DE602006010956D1 (de) 2010-01-21

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