DE602006013151D1 - Verfahren zur herstellung von polymermaleimiden - Google Patents
Verfahren zur herstellung von polymermaleimidenInfo
- Publication number
- DE602006013151D1 DE602006013151D1 DE602006013151T DE602006013151T DE602006013151D1 DE 602006013151 D1 DE602006013151 D1 DE 602006013151D1 DE 602006013151 T DE602006013151 T DE 602006013151T DE 602006013151 T DE602006013151 T DE 602006013151T DE 602006013151 D1 DE602006013151 D1 DE 602006013151D1
- Authority
- DE
- Germany
- Prior art keywords
- polymermalimides
- producing
- conjugates
- maleimide
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/91—Polymers modified by chemical after-treatment
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
- C08G73/06—Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromolecule
- C08G73/10—Polyimides; Polyester-imides; Polyamide-imides; Polyamide acids or similar polyimide precursors
- C08G73/12—Unsaturated polyimide precursors
- C08G73/121—Preparatory processes from unsaturated precursors and polyamines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
- C07D207/444—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5
- C07D207/448—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide
- C07D207/452—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide with hydrocarbon radicals, substituted by hetero atoms, directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/333—Polymers modified by chemical after-treatment with organic compounds containing nitrogen
- C08G65/33331—Polymers modified by chemical after-treatment with organic compounds containing nitrogen containing imide group
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
- C08G73/06—Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromolecule
- C08G73/10—Polyimides; Polyester-imides; Polyamide-imides; Polyamide acids or similar polyimide precursors
- C08G73/12—Unsaturated polyimide precursors
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70097205P | 2005-07-19 | 2005-07-19 | |
PCT/US2006/028271 WO2007012059A2 (en) | 2005-07-19 | 2006-07-19 | Method for preparing polymer maleimides |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602006013151D1 true DE602006013151D1 (de) | 2010-05-06 |
Family
ID=37667637
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602006013151T Active DE602006013151D1 (de) | 2005-07-19 | 2006-07-19 | Verfahren zur herstellung von polymermaleimiden |
Country Status (12)
Country | Link |
---|---|
US (4) | US7872082B2 (de) |
EP (1) | EP1915412B1 (de) |
JP (1) | JP5600240B2 (de) |
KR (1) | KR101334541B1 (de) |
CN (1) | CN101268118B (de) |
AT (1) | ATE461960T1 (de) |
AU (1) | AU2006269845B2 (de) |
CA (1) | CA2614987C (de) |
DE (1) | DE602006013151D1 (de) |
ES (1) | ES2341285T3 (de) |
MX (1) | MX2008000867A (de) |
WO (1) | WO2007012059A2 (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2341285T3 (es) * | 2005-07-19 | 2010-06-17 | Nektar Therapeutics | Metodo para preparar maleimidas polimericas. |
DE102007034580B4 (de) * | 2007-07-13 | 2012-11-08 | NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen | Biomaterial basierend auf einem hydrophilen polymeren Träger |
KR100771100B1 (ko) * | 2007-07-18 | 2007-10-29 | 아이디비켐(주) | 고순도의 메톡시폴리에틸렌글리콜에틸말레이미드의제조방법 |
RU2447083C1 (ru) * | 2010-07-20 | 2012-04-10 | Закрытое Акционерное Общество "Биокад" | НОВЫЙ ФУНКЦИОНАЛЬНО АКТИВНЫЙ ВЫСОКООЧИЩЕННЫЙ СТАБИЛЬНЫЙ КОНЪЮГАТ ИНТЕРФЕРОНА α С ПОЛИЭТИЛЕНГЛИКОЛЕМ, ПРЕДСТАВЛЕННЫЙ ОДНИМ ПОЗИЦИОННЫМ ИЗОМЕРОМ ПЭГ-NαH-ИФН, С УМЕНЬШЕННОЙ ИММУНОГЕННОСТЬЮ, С ПРОЛОНГИРОВАННЫМ БИОЛОГИЧЕСКИМ ДЕЙСТВИЕМ, ПРИГОДНЫЙ ДЛЯ МЕДИЦИНСКОГО ПРИМЕНЕНИЯ, И ИММУНОБИОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ |
WO2012123519A2 (en) | 2011-03-15 | 2012-09-20 | Novo Nordisk A/S | Human insulin analogues and derivatives comprising cysteine substitutions |
US8815226B2 (en) | 2011-06-10 | 2014-08-26 | Mersana Therapeutics, Inc. | Protein-polymer-drug conjugates |
ES2622578T3 (es) | 2011-06-10 | 2017-07-06 | Mersana Therapeutics, Inc. | Conjugados de proteína-polímero-fármaco |
WO2015046163A1 (ja) * | 2013-09-30 | 2015-04-02 | 株式会社フジミインコーポレーテッド | 研磨用組成物およびその製造方法 |
AU2014331714B2 (en) | 2013-10-11 | 2019-05-02 | Mersana Therapeutics, Inc. | Protein-polymer-drug conjugates |
CN105813655B (zh) | 2013-10-11 | 2022-03-15 | 阿萨纳生物科技有限责任公司 | 蛋白-聚合物-药物缀合物 |
US20200188476A1 (en) * | 2017-04-18 | 2020-06-18 | The Regents Of The University Of California | Anti-microbial agent-polymer conjugates and methods of use thereof |
AU2019209930B2 (en) | 2018-01-17 | 2023-08-03 | Magic Leap, Inc. | Eye center of rotation determination, depth plane selection, and render camera positioning in display systems |
WO2019143864A1 (en) | 2018-01-17 | 2019-07-25 | Magic Leap, Inc. | Display systems and methods for determining registration between a display and a user's eyes |
CN112689869A (zh) | 2018-07-24 | 2021-04-20 | 奇跃公司 | 用于确定显示器与用户的眼睛之间的配准的显示系统和方法 |
CN112898561A (zh) * | 2021-01-27 | 2021-06-04 | 大连理工大学 | 马来酰亚胺封端聚苯醚及其制备方法 |
CN114409836B (zh) * | 2021-12-20 | 2023-05-05 | 中国科学院化学研究所 | 一种非共轭型荧光材料及其制备方法和应用 |
Family Cites Families (43)
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FR2031538A1 (en) | 1969-02-20 | 1970-11-20 | Eastman Kodak Co | Maleimide and its n-substd derivs prepn |
US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
US4675414A (en) | 1985-03-08 | 1987-06-23 | The United States Of America As Represented By The Secretary Of The Navy | Maleimidomethyl-carbonate polyethers |
US4775729A (en) | 1985-03-08 | 1988-10-04 | The United States Of America As Represented By The Secretary Of The Navy | Curable polyether compositions |
JPH0730021B2 (ja) | 1986-03-05 | 1995-04-05 | 旭化成工業株式会社 | ポリマレイミド化合物 |
EP0318162A3 (de) * | 1987-11-25 | 1990-11-07 | Texaco Development Corporation | Bismaleinimid-Derivate |
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US7432330B2 (en) * | 2002-12-31 | 2008-10-07 | Nektar Therapeutics Al, Corporation | Hydrolytically stable maleimide-terminated polymers |
CA2509260C (en) | 2002-12-31 | 2012-10-02 | Nektar Therapeutics Al, Corporation | Maleamic acid polymer derivatives and their bioconjugates |
US7635734B2 (en) * | 2004-02-17 | 2009-12-22 | The Children's Hospital Of Philadelphia | Photochemical activation of surfaces for attaching biomaterial |
KR100512483B1 (ko) | 2003-05-07 | 2005-09-05 | 선바이오(주) | 신규한 폴리에틸렌글리콜-말레이미드 유도체의 합성방법 |
US7790835B2 (en) | 2003-12-03 | 2010-09-07 | Nektar Therapeutics | Method of preparing maleimide functionalized polymers |
ES2341285T3 (es) | 2005-07-19 | 2010-06-17 | Nektar Therapeutics | Metodo para preparar maleimidas polimericas. |
-
2006
- 2006-07-19 ES ES06788037T patent/ES2341285T3/es active Active
- 2006-07-19 KR KR1020087001883A patent/KR101334541B1/ko active IP Right Grant
- 2006-07-19 AU AU2006269845A patent/AU2006269845B2/en active Active
- 2006-07-19 CN CN2006800343128A patent/CN101268118B/zh active Active
- 2006-07-19 US US11/490,268 patent/US7872082B2/en active Active
- 2006-07-19 JP JP2008522977A patent/JP5600240B2/ja active Active
- 2006-07-19 AT AT06788037T patent/ATE461960T1/de not_active IP Right Cessation
- 2006-07-19 DE DE602006013151T patent/DE602006013151D1/de active Active
- 2006-07-19 WO PCT/US2006/028271 patent/WO2007012059A2/en active Application Filing
- 2006-07-19 MX MX2008000867A patent/MX2008000867A/es active IP Right Grant
- 2006-07-19 CA CA2614987A patent/CA2614987C/en active Active
- 2006-07-19 EP EP06788037A patent/EP1915412B1/de active Active
-
2010
- 2010-11-04 US US12/940,009 patent/US8058385B2/en active Active
-
2011
- 2011-10-04 US US13/252,761 patent/US8227558B2/en active Active
-
2012
- 2012-06-21 US US13/529,224 patent/US20120271000A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP5600240B2 (ja) | 2014-10-01 |
KR20080027878A (ko) | 2008-03-28 |
ATE461960T1 (de) | 2010-04-15 |
US7872082B2 (en) | 2011-01-18 |
US20120022220A1 (en) | 2012-01-26 |
MX2008000867A (es) | 2008-04-04 |
US20120271000A1 (en) | 2012-10-25 |
CN101268118B (zh) | 2012-09-19 |
US20110046315A1 (en) | 2011-02-24 |
CN101268118A (zh) | 2008-09-17 |
AU2006269845B2 (en) | 2012-03-22 |
EP1915412B1 (de) | 2010-03-24 |
US20070049688A1 (en) | 2007-03-01 |
KR101334541B1 (ko) | 2013-11-28 |
ES2341285T3 (es) | 2010-06-17 |
WO2007012059A2 (en) | 2007-01-25 |
WO2007012059A3 (en) | 2007-05-03 |
CA2614987C (en) | 2013-10-08 |
AU2006269845A1 (en) | 2007-01-25 |
JP2009503150A (ja) | 2009-01-29 |
EP1915412A2 (de) | 2008-04-30 |
US8227558B2 (en) | 2012-07-24 |
US8058385B2 (en) | 2011-11-15 |
CA2614987A1 (en) | 2007-01-25 |
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