MX2008000867A - Metodo para preparar polimeros de maleimidas. - Google Patents
Metodo para preparar polimeros de maleimidas.Info
- Publication number
- MX2008000867A MX2008000867A MX2008000867A MX2008000867A MX2008000867A MX 2008000867 A MX2008000867 A MX 2008000867A MX 2008000867 A MX2008000867 A MX 2008000867A MX 2008000867 A MX2008000867 A MX 2008000867A MX 2008000867 A MX2008000867 A MX 2008000867A
- Authority
- MX
- Mexico
- Prior art keywords
- preparing polymer
- polymer maleimides
- polymeric reagents
- maleimides
- preparing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/91—Polymers modified by chemical after-treatment
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
- C08G73/06—Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromolecule
- C08G73/10—Polyimides; Polyester-imides; Polyamide-imides; Polyamide acids or similar polyimide precursors
- C08G73/12—Unsaturated polyimide precursors
- C08G73/121—Preparatory processes from unsaturated precursors and polyamines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
- C07D207/444—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5
- C07D207/448—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide
- C07D207/452—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide with hydrocarbon radicals, substituted by hetero atoms, directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/333—Polymers modified by chemical after-treatment with organic compounds containing nitrogen
- C08G65/33331—Polymers modified by chemical after-treatment with organic compounds containing nitrogen containing imide group
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
- C08G73/06—Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromolecule
- C08G73/10—Polyimides; Polyester-imides; Polyamide-imides; Polyamide acids or similar polyimide precursors
- C08G73/12—Unsaturated polyimide precursors
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Polyethers (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Abstract
Se proporcionan metodos para preparar reactivos polimericos que porten una maleimida; tambien se proporcionan composiciones que comprenden los reactivos polimericos, asi como conjugados preparados mediante reactivos polimericos obtenidos con los metodos descritos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70097205P | 2005-07-19 | 2005-07-19 | |
PCT/US2006/028271 WO2007012059A2 (en) | 2005-07-19 | 2006-07-19 | Method for preparing polymer maleimides |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2008000867A true MX2008000867A (es) | 2008-04-04 |
Family
ID=37667637
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2008000867A MX2008000867A (es) | 2005-07-19 | 2006-07-19 | Metodo para preparar polimeros de maleimidas. |
Country Status (12)
Country | Link |
---|---|
US (4) | US7872082B2 (es) |
EP (1) | EP1915412B1 (es) |
JP (1) | JP5600240B2 (es) |
KR (1) | KR101334541B1 (es) |
CN (1) | CN101268118B (es) |
AT (1) | ATE461960T1 (es) |
AU (1) | AU2006269845B2 (es) |
CA (1) | CA2614987C (es) |
DE (1) | DE602006013151D1 (es) |
ES (1) | ES2341285T3 (es) |
MX (1) | MX2008000867A (es) |
WO (1) | WO2007012059A2 (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1915412B1 (en) * | 2005-07-19 | 2010-03-24 | Nektar Therapeutics | Method for preparing polymer maleimides |
DE102007034580B4 (de) * | 2007-07-13 | 2012-11-08 | NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen | Biomaterial basierend auf einem hydrophilen polymeren Träger |
KR100771100B1 (ko) * | 2007-07-18 | 2007-10-29 | 아이디비켐(주) | 고순도의 메톡시폴리에틸렌글리콜에틸말레이미드의제조방법 |
RU2447083C1 (ru) * | 2010-07-20 | 2012-04-10 | Закрытое Акционерное Общество "Биокад" | НОВЫЙ ФУНКЦИОНАЛЬНО АКТИВНЫЙ ВЫСОКООЧИЩЕННЫЙ СТАБИЛЬНЫЙ КОНЪЮГАТ ИНТЕРФЕРОНА α С ПОЛИЭТИЛЕНГЛИКОЛЕМ, ПРЕДСТАВЛЕННЫЙ ОДНИМ ПОЗИЦИОННЫМ ИЗОМЕРОМ ПЭГ-NαH-ИФН, С УМЕНЬШЕННОЙ ИММУНОГЕННОСТЬЮ, С ПРОЛОНГИРОВАННЫМ БИОЛОГИЧЕСКИМ ДЕЙСТВИЕМ, ПРИГОДНЫЙ ДЛЯ МЕДИЦИНСКОГО ПРИМЕНЕНИЯ, И ИММУНОБИОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ |
JP2014509603A (ja) | 2011-03-15 | 2014-04-21 | ノヴォ ノルディスク アー/エス | システイン置換を含むヒトインスリン類似体およびヒトインスリン誘導体 |
MX368966B (es) | 2011-06-10 | 2019-10-23 | Mersana Therapeutics Inc | Conjugados de proteina-polimero-farmaco. |
US8815226B2 (en) | 2011-06-10 | 2014-08-26 | Mersana Therapeutics, Inc. | Protein-polymer-drug conjugates |
JP5892638B2 (ja) * | 2013-09-30 | 2016-03-23 | 株式会社フジミインコーポレーテッド | 研磨用組成物およびその製造方法 |
JP6427564B2 (ja) | 2013-10-11 | 2018-11-21 | アサナ・バイオサイエンシズ,リミテッド・ライアビリティ・カンパニー | タンパク質−ポリマー−薬物共役体 |
EP3054991B1 (en) | 2013-10-11 | 2019-04-03 | Mersana Therapeutics, Inc. | Protein-polymer-drug conjugates |
US20200188476A1 (en) * | 2017-04-18 | 2020-06-18 | The Regents Of The University Of California | Anti-microbial agent-polymer conjugates and methods of use thereof |
KR20200110367A (ko) | 2018-01-17 | 2020-09-23 | 매직 립, 인코포레이티드 | 디스플레이 시스템들에서의 눈 회전 중심 결정, 깊이 평면 선택, 및 렌더 카메라 포지셔닝 |
IL275824B1 (en) | 2018-01-17 | 2024-04-01 | Magic Leap Inc | Display systems and methods for determining registration between a display and a user's eyes |
WO2020023542A1 (en) | 2018-07-24 | 2020-01-30 | Magic Leap, Inc. | Display systems and methods for determining registration between a display and eyes of a user |
CN112898561A (zh) * | 2021-01-27 | 2021-06-04 | 大连理工大学 | 马来酰亚胺封端聚苯醚及其制备方法 |
CN114409836B (zh) * | 2021-12-20 | 2023-05-05 | 中国科学院化学研究所 | 一种非共轭型荧光材料及其制备方法和应用 |
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FR2031538A1 (en) | 1969-02-20 | 1970-11-20 | Eastman Kodak Co | Maleimide and its n-substd derivs prepn |
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US4675414A (en) | 1985-03-08 | 1987-06-23 | The United States Of America As Represented By The Secretary Of The Navy | Maleimidomethyl-carbonate polyethers |
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JP2505581B2 (ja) | 1989-06-12 | 1996-06-12 | 帝人株式会社 | 硬化性不飽和イミドウレタン組成物、その製造法及び硬化成型物 |
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TW593427B (en) | 2000-12-18 | 2004-06-21 | Nektar Therapeutics Al Corp | Synthesis of high molecular weight non-peptidic polymer derivatives |
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US20030153491A1 (en) | 2002-01-11 | 2003-08-14 | Winslow Robert M. | Methods and compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin |
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AU2003300133B2 (en) * | 2002-12-31 | 2008-11-13 | Nektar Therapeutics | Hydrolytically stable maleimide-terminated polymers |
ATE399185T1 (de) | 2002-12-31 | 2008-07-15 | Nektar Therapeutics Al Corp | Maleinsäureamid polymerderivate und ihre biokonjugate |
US7635734B2 (en) * | 2004-02-17 | 2009-12-22 | The Children's Hospital Of Philadelphia | Photochemical activation of surfaces for attaching biomaterial |
KR100512483B1 (ko) | 2003-05-07 | 2005-09-05 | 선바이오(주) | 신규한 폴리에틸렌글리콜-말레이미드 유도체의 합성방법 |
AU2004297228A1 (en) | 2003-12-03 | 2005-06-23 | Nektar Therapeutics Al, Corporation | Method of preparing maleimide functionalized polymers |
EP1915412B1 (en) | 2005-07-19 | 2010-03-24 | Nektar Therapeutics | Method for preparing polymer maleimides |
-
2006
- 2006-07-19 EP EP06788037A patent/EP1915412B1/en active Active
- 2006-07-19 CN CN2006800343128A patent/CN101268118B/zh active Active
- 2006-07-19 CA CA2614987A patent/CA2614987C/en active Active
- 2006-07-19 MX MX2008000867A patent/MX2008000867A/es active IP Right Grant
- 2006-07-19 US US11/490,268 patent/US7872082B2/en active Active
- 2006-07-19 KR KR1020087001883A patent/KR101334541B1/ko active IP Right Grant
- 2006-07-19 AT AT06788037T patent/ATE461960T1/de not_active IP Right Cessation
- 2006-07-19 JP JP2008522977A patent/JP5600240B2/ja active Active
- 2006-07-19 ES ES06788037T patent/ES2341285T3/es active Active
- 2006-07-19 WO PCT/US2006/028271 patent/WO2007012059A2/en active Application Filing
- 2006-07-19 AU AU2006269845A patent/AU2006269845B2/en active Active
- 2006-07-19 DE DE602006013151T patent/DE602006013151D1/de active Active
-
2010
- 2010-11-04 US US12/940,009 patent/US8058385B2/en active Active
-
2011
- 2011-10-04 US US13/252,761 patent/US8227558B2/en active Active
-
2012
- 2012-06-21 US US13/529,224 patent/US20120271000A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ES2341285T3 (es) | 2010-06-17 |
US8058385B2 (en) | 2011-11-15 |
ATE461960T1 (de) | 2010-04-15 |
EP1915412B1 (en) | 2010-03-24 |
DE602006013151D1 (de) | 2010-05-06 |
AU2006269845A1 (en) | 2007-01-25 |
US20120022220A1 (en) | 2012-01-26 |
CN101268118A (zh) | 2008-09-17 |
KR101334541B1 (ko) | 2013-11-28 |
US20110046315A1 (en) | 2011-02-24 |
CA2614987A1 (en) | 2007-01-25 |
KR20080027878A (ko) | 2008-03-28 |
EP1915412A2 (en) | 2008-04-30 |
WO2007012059A3 (en) | 2007-05-03 |
JP2009503150A (ja) | 2009-01-29 |
US7872082B2 (en) | 2011-01-18 |
CN101268118B (zh) | 2012-09-19 |
AU2006269845B2 (en) | 2012-03-22 |
US8227558B2 (en) | 2012-07-24 |
CA2614987C (en) | 2013-10-08 |
US20120271000A1 (en) | 2012-10-25 |
JP5600240B2 (ja) | 2014-10-01 |
WO2007012059A2 (en) | 2007-01-25 |
US20070049688A1 (en) | 2007-03-01 |
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