DE602005021913D1 - Herstellung von dicarbonsäure durch verbesserte yarrowia lipolytica-mutantenstämme - Google Patents

Herstellung von dicarbonsäure durch verbesserte yarrowia lipolytica-mutantenstämme

Info

Publication number
DE602005021913D1
DE602005021913D1 DE602005021913T DE602005021913T DE602005021913D1 DE 602005021913 D1 DE602005021913 D1 DE 602005021913D1 DE 602005021913 T DE602005021913 T DE 602005021913T DE 602005021913 T DE602005021913 T DE 602005021913T DE 602005021913 D1 DE602005021913 D1 DE 602005021913D1
Authority
DE
Germany
Prior art keywords
yarrowia lipolytica
mutanests
preparation
improved
dicarboxylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602005021913T
Other languages
German (de)
English (en)
Inventor
Jean-Marc Nicaud
France Thevenieau
Dall Marie-Therese Le
Remy Marchal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
IFP Energies Nouvelles IFPEN
Original Assignee
Centre National de la Recherche Scientifique CNRS
IFP Energies Nouvelles IFPEN
Institut National de la Recherche Agronomique INRA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, IFP Energies Nouvelles IFPEN, Institut National de la Recherche Agronomique INRA filed Critical Centre National de la Recherche Scientifique CNRS
Publication of DE602005021913D1 publication Critical patent/DE602005021913D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0036—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
    • C12N9/0038—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6) with a heme protein as acceptor (1.6.2)
    • C12N9/0042—NADPH-cytochrome P450 reductase (1.6.2.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0077—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with a reduced iron-sulfur protein as one donor (1.14.15)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE602005021913T 2004-12-15 2005-12-13 Herstellung von dicarbonsäure durch verbesserte yarrowia lipolytica-mutantenstämme Expired - Lifetime DE602005021913D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0413468A FR2879215B1 (fr) 2004-12-15 2004-12-15 Production d'acides dicarboxyliques par des souches mutantes ameliorees de yarrowia lipolytica
PCT/FR2005/003140 WO2006064131A1 (fr) 2004-12-15 2005-12-13 Production d’acides dicarboxyliques par des souches mutantes ameliorees de yarrowia lipolytica

Publications (1)

Publication Number Publication Date
DE602005021913D1 true DE602005021913D1 (de) 2010-07-29

Family

ID=34954795

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005021913T Expired - Lifetime DE602005021913D1 (de) 2004-12-15 2005-12-13 Herstellung von dicarbonsäure durch verbesserte yarrowia lipolytica-mutantenstämme

Country Status (13)

Country Link
US (1) US20100041115A1 (https=)
EP (1) EP1828392B1 (https=)
JP (3) JP2008523794A (https=)
CN (1) CN101228282B (https=)
AT (1) ATE471384T1 (https=)
BR (1) BRPI0519928A2 (https=)
CA (1) CA2590795C (https=)
DE (1) DE602005021913D1 (https=)
DK (1) DK1828392T3 (https=)
ES (1) ES2346773T3 (https=)
FR (1) FR2879215B1 (https=)
PL (1) PL1828392T3 (https=)
WO (1) WO2006064131A1 (https=)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2927089B1 (fr) 2008-02-05 2011-03-25 Inst Nat De La Rech Agronomique Inra Procede d'integration ciblee de multicopies d'un gene d'interet dans une souche de yarrowia
US8597931B2 (en) 2008-07-11 2013-12-03 Institut National De La Recherche Agronomique (Inra) Mutant yeast strains capable of accumulating a large quantity of lipids
FR2957074B1 (fr) 2010-03-05 2012-04-27 Organisation Nationale Interprofessionnelle Des Graines Et Fruits Oleagineux O N I D O L Procede de preparation d'acides carboxyliques par coupure oxydante d'un diol vicinal
FR2962133B1 (fr) 2010-07-01 2014-09-12 Agronomique Inst Nat Rech Optimisation de la synthese et de l'accumulation de lipides
WO2013006733A2 (en) 2011-07-06 2013-01-10 Verdezyne, Inc. Biological methods for preparing a fatty dicarboxylic acid
SG10201705057QA (en) 2012-12-19 2017-07-28 Verdezyne Inc Biological methods for preparing a fatty dicarboxylic acid
HUE052914T2 (hu) 2012-12-19 2021-05-28 Corvay Bioproducts Gmbh Biológiai eljárások zsírdikarbonsav elõállítására
FR3002774A1 (fr) 2013-03-04 2014-09-05 Agronomique Inst Nat Rech Levures mutantes ayant une production accrue de lipides et d'acide citrique
FR3005317B1 (fr) 2013-05-02 2016-03-18 Agronomique Inst Nat Rech Levures mutantes capables de produire un acide gras inhabituel
DE102014220186B4 (de) * 2013-12-12 2017-06-22 Technische Universität Dresden Hefestämme und Verfahren zur Produktion von Omega-Hydroxyfettsäuren und Dicarbonsäuren
EP3155094A1 (en) 2014-06-11 2017-04-19 Institut National De La Recherche Agronomique (INRA) Improved lipid accumulation in yarrowia lipolytica strains by overexpression of hexokinase and new strains thereof
US10174350B2 (en) 2014-07-18 2019-01-08 Industrial Technology Research Institute Genetically modified microorganism for producing medium-chain lauric acid and/or dodecanedioic acid and method of using thereof
US9695404B2 (en) 2014-07-18 2017-07-04 Industrial Technology Research Institute Genetically modified microorganism for producing long-chain dicarboxylic acid and method of using thereof
US9932665B2 (en) 2015-01-22 2018-04-03 United Technologies Corporation Corrosion resistant coating application method
CA2979423A1 (fr) 2015-03-27 2016-10-06 Fonds De Developpement Des Filieres Des Oleagineux Et Des Proteagineux Fidop Microorganismes et leur utilisation pour la production de diacides
EP3085788A1 (en) 2015-04-23 2016-10-26 Institut National De La Recherche Agronomique Mutant yeast strain capable of degrading cellobiose
EP3106520A1 (en) 2015-06-17 2016-12-21 Institut National De La Recherche Agronomique Mutant yarrowia strain capable of degrading galactose
EP3325607A1 (en) * 2015-07-22 2018-05-30 E. I. du Pont de Nemours and Company High level production of long-chain dicarboxylic acids with microbes
KR101903553B1 (ko) * 2015-10-27 2018-10-04 한국생명공학연구원 중쇄 아미노카르복시산의 생산 방법
US20190136278A1 (en) 2016-05-10 2019-05-09 Institut National De La Recherche Agronomique Mutant yeast strains with enhanced production of erythritol or erythrulose
EP3348647A1 (en) 2017-01-13 2018-07-18 Institut National De La Recherche Agronomique Mutant yeast strain capable of producing medium chain fatty acids
EP3360956A1 (en) 2017-02-10 2018-08-15 Institut National De La Recherche Agronomique Mutant yeast strain capable of degrading cellulose
CN107083338A (zh) * 2017-05-15 2017-08-22 天津大学 重组菌株及其构建方法与在产菜油甾醇中的应用
CA3069697A1 (en) 2017-07-13 2019-01-17 Radici Chimica S.P.A. Biological methods for modifying cellular carbon flux
CN110684676B (zh) * 2018-07-06 2023-08-08 上海凯赛生物技术股份有限公司 一种低含量羟基酸杂质的长链二元酸及其生产方法
US11136596B2 (en) * 2018-07-06 2021-10-05 Cibt America Inc. Long-chain dibasic acid with low content of hydroxyl acid impurity and production method thereof
CN111117982B (zh) * 2019-12-25 2023-05-12 武汉新华扬生物股份有限公司 一种拟除虫菊酯降解酶、其编码基因、重组菌株和应用
US20230089404A1 (en) 2021-09-18 2023-03-23 Indian Oil Corporation Limited Bioassisted Process For Selective Conversion Of Alkane Rich Refinery Stream
CN114958900B (zh) * 2022-05-16 2024-04-19 华中科技大学 一种解脂耶氏酵母高效无标记基因整合载体及其应用
WO2026008448A1 (en) 2024-07-01 2026-01-08 Universiteit Gent Modified yeast strains to produce long chain dicarboxylic acids

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Publication number Priority date Publication date Assignee Title
DE3540834A1 (de) 1985-11-18 1987-05-21 Henkel Kgaa Verfahren zur herstellung von dicarbonsaeuren
US5254466A (en) 1989-11-06 1993-10-19 Henkel Research Corporation Site-specific modification of the candida tropicals genome
WO1991014781A1 (en) * 1990-03-19 1991-10-03 Henkel Research Corporation METHOD FOR INCREASING THE OMEGA-HYDROXYLASE ACTIVITY IN $i(CANDIDA TROPICALIS)
US6673613B2 (en) * 2000-07-26 2004-01-06 Cognis Corporation Use of CYP52A2A promoter to increase gene expression in yeast
WO2003100013A2 (en) * 2002-05-23 2003-12-04 Cognis Corporation NON-REVERTIBLE β-OXIDATION BLOCKED CANDIDA TROPICALIS

Also Published As

Publication number Publication date
CN101228282B (zh) 2013-09-18
JP5462303B2 (ja) 2014-04-02
WO2006064131A8 (fr) 2007-08-02
EP1828392A1 (fr) 2007-09-05
EP1828392B1 (fr) 2010-06-16
FR2879215A1 (fr) 2006-06-16
JP2008523794A (ja) 2008-07-10
JP2012130352A (ja) 2012-07-12
CA2590795C (fr) 2014-09-02
ES2346773T3 (es) 2010-10-20
WO2006064131A1 (fr) 2006-06-22
CA2590795A1 (fr) 2006-06-22
ATE471384T1 (de) 2010-07-15
BRPI0519928A2 (pt) 2009-04-07
JP2012105680A (ja) 2012-06-07
FR2879215B1 (fr) 2010-08-20
PL1828392T3 (pl) 2011-04-29
JP5615859B2 (ja) 2014-10-29
DK1828392T3 (da) 2010-09-27
CN101228282A (zh) 2008-07-23
US20100041115A1 (en) 2010-02-18

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: IFP ENERGIES NOUVELLES, RUEIL-MALMAISON, FR

Owner name: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (, FR

Owner name: INSTITUT FRANCAIS DU PETROLE, RUEIL-MALMAISON,, FR