DK1828392T3 - Fremstilling af dicarboxylsyrer ved hjælp af forbedret mutantstamme af Yarrowia lipolytica - Google Patents

Fremstilling af dicarboxylsyrer ved hjælp af forbedret mutantstamme af Yarrowia lipolytica

Info

Publication number
DK1828392T3
DK1828392T3 DK05826569.5T DK05826569T DK1828392T3 DK 1828392 T3 DK1828392 T3 DK 1828392T3 DK 05826569 T DK05826569 T DK 05826569T DK 1828392 T3 DK1828392 T3 DK 1828392T3
Authority
DK
Denmark
Prior art keywords
dicarboxylic acids
yarrowia lipolytica
mutant strain
preparation
carbon atoms
Prior art date
Application number
DK05826569.5T
Other languages
English (en)
Inventor
Jean-Marc Nicaud
Remy Marchal
Dall Marie-Therese Le
France Thevenieau
Original Assignee
Inst Francais Du Petrole
Agronomique Inst Nat Rech
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Francais Du Petrole, Agronomique Inst Nat Rech, Centre Nat Rech Scient filed Critical Inst Francais Du Petrole
Application granted granted Critical
Publication of DK1828392T3 publication Critical patent/DK1828392T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0036—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
    • C12N9/0038—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6) with a heme protein as acceptor (1.6.2)
    • C12N9/0042—NADPH-cytochrome P450 reductase (1.6.2.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0077—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with a reduced iron-sulfur protein as one donor (1.14.15)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK05826569.5T 2004-12-15 2005-12-13 Fremstilling af dicarboxylsyrer ved hjælp af forbedret mutantstamme af Yarrowia lipolytica DK1828392T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0413468A FR2879215B1 (fr) 2004-12-15 2004-12-15 Production d'acides dicarboxyliques par des souches mutantes ameliorees de yarrowia lipolytica
PCT/FR2005/003140 WO2006064131A1 (fr) 2004-12-15 2005-12-13 Production d’acides dicarboxyliques par des souches mutantes ameliorees de yarrowia lipolytica

Publications (1)

Publication Number Publication Date
DK1828392T3 true DK1828392T3 (da) 2010-09-27

Family

ID=34954795

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05826569.5T DK1828392T3 (da) 2004-12-15 2005-12-13 Fremstilling af dicarboxylsyrer ved hjælp af forbedret mutantstamme af Yarrowia lipolytica

Country Status (13)

Country Link
US (1) US20100041115A1 (da)
EP (1) EP1828392B1 (da)
JP (3) JP2008523794A (da)
CN (1) CN101228282B (da)
AT (1) ATE471384T1 (da)
BR (1) BRPI0519928A2 (da)
CA (1) CA2590795C (da)
DE (1) DE602005021913D1 (da)
DK (1) DK1828392T3 (da)
ES (1) ES2346773T3 (da)
FR (1) FR2879215B1 (da)
PL (1) PL1828392T3 (da)
WO (1) WO2006064131A1 (da)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2927089B1 (fr) 2008-02-05 2011-03-25 Inst Nat De La Rech Agronomique Inra Procede d'integration ciblee de multicopies d'un gene d'interet dans une souche de yarrowia
DK2310517T3 (da) 2008-07-11 2016-06-06 Inst Nat De La Rech Agronomique (Inra) Hidtil ukendte mutante gærstammer med evne til at ophobe en stor mængde lipider
FR2957074B1 (fr) 2010-03-05 2012-04-27 Organisation Nationale Interprofessionnelle Des Graines Et Fruits Oleagineux O N I D O L Procede de preparation d'acides carboxyliques par coupure oxydante d'un diol vicinal
FR2962133B1 (fr) 2010-07-01 2014-09-12 Agronomique Inst Nat Rech Optimisation de la synthese et de l'accumulation de lipides
MY166952A (en) 2011-07-06 2018-07-25 Verdezyne Inc Biological methods for preparing a fatty dicarboxylic acid
US9909151B2 (en) 2012-12-19 2018-03-06 Verdezyne, Inc. Biological methods for preparing a fatty dicarboxylic acid
SG10201705057QA (en) * 2012-12-19 2017-07-28 Verdezyne Inc Biological methods for preparing a fatty dicarboxylic acid
FR3002774A1 (fr) 2013-03-04 2014-09-05 Agronomique Inst Nat Rech Levures mutantes ayant une production accrue de lipides et d'acide citrique
FR3005317B1 (fr) 2013-05-02 2016-03-18 Agronomique Inst Nat Rech Levures mutantes capables de produire un acide gras inhabituel
DE102014220186B4 (de) 2013-12-12 2017-06-22 Technische Universität Dresden Hefestämme und Verfahren zur Produktion von Omega-Hydroxyfettsäuren und Dicarbonsäuren
US20170145449A1 (en) 2014-06-11 2017-05-25 Institut National De La Recherche Agronomique Improved lipid accumulation in Yarrowia lipolytica strains by overexpression of hexokinase and new strains thereof
US10174350B2 (en) 2014-07-18 2019-01-08 Industrial Technology Research Institute Genetically modified microorganism for producing medium-chain lauric acid and/or dodecanedioic acid and method of using thereof
US9695404B2 (en) 2014-07-18 2017-07-04 Industrial Technology Research Institute Genetically modified microorganism for producing long-chain dicarboxylic acid and method of using thereof
US9932665B2 (en) 2015-01-22 2018-04-03 United Technologies Corporation Corrosion resistant coating application method
EP3274464A1 (fr) 2015-03-27 2018-01-31 Fonds de Developpement des Filières des Oleagineux et Proteagineux FIDOP Microorganismes et leur utilisation pour la production de diacides
EP3085788A1 (en) 2015-04-23 2016-10-26 Institut National De La Recherche Agronomique Mutant yeast strain capable of degrading cellobiose
EP3106520A1 (en) 2015-06-17 2016-12-21 Institut National De La Recherche Agronomique Mutant yarrowia strain capable of degrading galactose
US10626424B2 (en) 2015-07-22 2020-04-21 Dupont Industrial Biosciences Usa, Llc High level production of long-chain dicarboxylic acids with microbes
KR101903553B1 (ko) * 2015-10-27 2018-10-04 한국생명공학연구원 중쇄 아미노카르복시산의 생산 방법
CA3023338A1 (en) 2016-05-10 2017-11-16 Institut National De La Recherche Agronomique Mutant yeast strains with enhanced production of erythritol or erythrulose
EP3348647A1 (en) 2017-01-13 2018-07-18 Institut National De La Recherche Agronomique Mutant yeast strain capable of producing medium chain fatty acids
EP3360956A1 (en) 2017-02-10 2018-08-15 Institut National De La Recherche Agronomique Mutant yeast strain capable of degrading cellulose
CN107083338A (zh) * 2017-05-15 2017-08-22 天津大学 重组菌株及其构建方法与在产菜油甾醇中的应用
WO2019014309A1 (en) * 2017-07-13 2019-01-17 Verdezyne (Abc), Llc BIOLOGICAL METHODS FOR MODIFYING A CELL CARBON FLOW
US11136596B2 (en) * 2018-07-06 2021-10-05 Cibt America Inc. Long-chain dibasic acid with low content of hydroxyl acid impurity and production method thereof
CN110684676B (zh) * 2018-07-06 2023-08-08 上海凯赛生物技术股份有限公司 一种低含量羟基酸杂质的长链二元酸及其生产方法
CN111117982B (zh) * 2019-12-25 2023-05-12 武汉新华扬生物股份有限公司 一种拟除虫菊酯降解酶、其编码基因、重组菌株和应用
US20230089404A1 (en) 2021-09-18 2023-03-23 Indian Oil Corporation Limited Bioassisted Process For Selective Conversion Of Alkane Rich Refinery Stream
CN114958900B (zh) * 2022-05-16 2024-04-19 华中科技大学 一种解脂耶氏酵母高效无标记基因整合载体及其应用

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3540834A1 (de) 1985-11-18 1987-05-21 Henkel Kgaa Verfahren zur herstellung von dicarbonsaeuren
US5254466A (en) 1989-11-06 1993-10-19 Henkel Research Corporation Site-specific modification of the candida tropicals genome
WO1991014781A1 (en) * 1990-03-19 1991-10-03 Henkel Research Corporation METHOD FOR INCREASING THE OMEGA-HYDROXYLASE ACTIVITY IN $i(CANDIDA TROPICALIS)
US6673613B2 (en) * 2000-07-26 2004-01-06 Cognis Corporation Use of CYP52A2A promoter to increase gene expression in yeast
AU2003247411A1 (en) * 2002-05-23 2003-12-12 Cognis Corporation NON-REVERTIBLE Beta-OXIDATION BLOCKED CANDIDA TROPICALIS

Also Published As

Publication number Publication date
CN101228282A (zh) 2008-07-23
CA2590795C (fr) 2014-09-02
JP5615859B2 (ja) 2014-10-29
DE602005021913D1 (de) 2010-07-29
CN101228282B (zh) 2013-09-18
JP2008523794A (ja) 2008-07-10
CA2590795A1 (fr) 2006-06-22
ES2346773T3 (es) 2010-10-20
FR2879215A1 (fr) 2006-06-16
ATE471384T1 (de) 2010-07-15
FR2879215B1 (fr) 2010-08-20
JP2012105680A (ja) 2012-06-07
EP1828392B1 (fr) 2010-06-16
JP2012130352A (ja) 2012-07-12
EP1828392A1 (fr) 2007-09-05
WO2006064131A8 (fr) 2007-08-02
PL1828392T3 (pl) 2011-04-29
JP5462303B2 (ja) 2014-04-02
US20100041115A1 (en) 2010-02-18
WO2006064131A1 (fr) 2006-06-22
BRPI0519928A2 (pt) 2009-04-07

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