DE602005019562D1 - Zur modulation des 5-ht6-rezeptors, des 5-ht2a-rezeptors oder beider rezeptoren geeignete arylsulfonylbenzodioxane - Google Patents
Zur modulation des 5-ht6-rezeptors, des 5-ht2a-rezeptors oder beider rezeptoren geeignete arylsulfonylbenzodioxaneInfo
- Publication number
- DE602005019562D1 DE602005019562D1 DE602005019562T DE602005019562T DE602005019562D1 DE 602005019562 D1 DE602005019562 D1 DE 602005019562D1 DE 602005019562 T DE602005019562 T DE 602005019562T DE 602005019562 T DE602005019562 T DE 602005019562T DE 602005019562 D1 DE602005019562 D1 DE 602005019562D1
- Authority
- DE
- Germany
- Prior art keywords
- receptor
- arylsulfonylbenzodioxane
- receptors
- modulating
- ht2a
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
- C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
- C07D327/06—Six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Child & Adolescent Psychology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US56831404P | 2004-05-05 | 2004-05-05 | |
PCT/EP2005/004479 WO2005105776A1 (en) | 2004-05-05 | 2005-04-27 | Arylsulfonyl benzodioxanes useful for modulation the 5-ht6 receptor, the 5-ht2areceptor or both |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602005019562D1 true DE602005019562D1 (de) | 2010-04-08 |
Family
ID=34965191
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005019562T Active DE602005019562D1 (de) | 2004-05-05 | 2005-04-27 | Zur modulation des 5-ht6-rezeptors, des 5-ht2a-rezeptors oder beider rezeptoren geeignete arylsulfonylbenzodioxane |
Country Status (21)
Country | Link |
---|---|
US (1) | US7368567B2 (de) |
EP (1) | EP1748995B1 (de) |
JP (1) | JP2007536302A (de) |
KR (1) | KR100823805B1 (de) |
CN (1) | CN100540546C (de) |
AR (1) | AR048936A1 (de) |
AT (1) | ATE458727T1 (de) |
AU (1) | AU2005238179B2 (de) |
BR (1) | BRPI0510642A (de) |
CA (1) | CA2566196A1 (de) |
DE (1) | DE602005019562D1 (de) |
ES (1) | ES2338668T3 (de) |
HK (1) | HK1104533A1 (de) |
IL (1) | IL178819A0 (de) |
MX (1) | MXPA06012621A (de) |
NO (1) | NO20065510L (de) |
NZ (1) | NZ550441A (de) |
RU (1) | RU2372344C2 (de) |
TW (1) | TWI298636B (de) |
WO (1) | WO2005105776A1 (de) |
ZA (1) | ZA200608588B (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2359725T3 (es) * | 2004-09-30 | 2011-05-26 | F. Hoffmann-La Roche Ag | Composiciones y métodos para el tratamiento de trastornos cognitivos. |
CA2591810A1 (en) * | 2004-12-21 | 2006-06-29 | F.Hoffmann-La Roche Ag | Chroman derivatives and uses thereof in the treatment of cns disorders |
BRPI0610046A2 (pt) * | 2005-04-22 | 2010-05-25 | Wyeth Corp | derivados de benzodioxano e benzodioxolano e usos destes |
RU2008115032A (ru) | 2005-11-03 | 2009-12-10 | Ф. Хоффманн-Ля Рош Аг (Ch) | Арилсульфонилхроманы в качестве ингибиторов 5-нт6 |
WO2007120596A1 (en) * | 2006-04-12 | 2007-10-25 | Wyeth | DIHYDRO[1,4]DIOXINO[2,3-e]INDAZOLE DERIVATIVES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS |
EP2041079A1 (de) * | 2006-06-20 | 2009-04-01 | F. Hoffmann-Roche AG | Arylsulfonylnaphthalinderivate und anwendungen davon |
FR2913886B1 (fr) | 2007-03-22 | 2012-03-02 | Guerbet Sa | Utilisation de nanoparticules metalliques dans le diagnostique de la maladie d'alzheimer |
BRPI0911772A2 (pt) * | 2008-04-29 | 2017-06-27 | Nsab Filial Af Neurosearch Sweden Ab Sverige | composto, composição farmacêutica, e, uso do composto. |
JP2011519839A (ja) * | 2008-04-29 | 2011-07-14 | エヌエスエイビー、フィリアル アヴ ノイロサーチ スウェーデン エービー、スヴェーリエ | ドーパミン神経伝達のモジュレーター |
WO2009133110A1 (en) | 2008-04-29 | 2009-11-05 | Nsab, Filial Af Neurosearch Sweden Ab, Sverige | Modulators of dopamine neurotransmission |
CN114890978B (zh) * | 2022-04-19 | 2023-07-25 | 宿迁医美科技有限公司 | 酚类化合物及其制备方法和应用 |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3901814A1 (de) | 1988-07-28 | 1990-02-01 | Bayer Ag | Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga |
TW224941B (de) * | 1989-11-08 | 1994-06-11 | Yamanouchi Pharma Co Ltd | |
US5506192A (en) | 1990-06-07 | 1996-04-09 | Sandoz Ltd. | Substituted phthalides and heterocyclic phthalides |
ATE161254T1 (de) | 1990-07-27 | 1998-01-15 | Chugai Pharmaceutical Co Ltd | Benzopyranderivat |
US5401848A (en) | 1990-11-26 | 1995-03-28 | E. R. Squibb & Sons, Inc. | Indane and quinoline derivatives |
US5817693A (en) | 1991-11-05 | 1998-10-06 | Cousins; Russell Donovan | Endothelin receptor antagonists |
ZA93436B (en) | 1992-01-24 | 1993-08-25 | Chugai Pharmaceutical Co Ltd | Benzopyran derivatives |
CN1044605C (zh) | 1992-08-17 | 1999-08-11 | 中外制药株式会社 | 苯并吡喃和苯并嗪衍生物 |
US5374643A (en) | 1992-09-11 | 1994-12-20 | E. R. Squibb & Sons, Inc. | Aryl urea (thiourea) and cyanoguanidine derivatives |
GB9309716D0 (en) * | 1993-05-12 | 1993-06-23 | Zeneca Ltd | Heterocyclic derivatives |
US5739135A (en) | 1993-09-03 | 1998-04-14 | Bristol-Myers Squibb Company | Inhibitors of microsomal triglyceride transfer protein and method |
US6150402A (en) | 1994-08-15 | 2000-11-21 | Loma Linda University Medical Center | Natriuretic compounds |
US5869478A (en) | 1995-06-07 | 1999-02-09 | Bristol-Myers Squibb Company | Sulfonamido substituted benzopyran derivatives |
MX9710260A (es) | 1995-06-30 | 1998-03-29 | Upjohn Co | Isocromanos 1, 6-disustituidos para el tratamiento de migrañas. |
US5663194A (en) | 1995-07-25 | 1997-09-02 | Mewshaw; Richard E. | Chroman-2-ylmethylamino derivatives |
US5935958A (en) | 1996-07-01 | 1999-08-10 | Schering Corporation | Muscarinic antagonists |
WO1998007418A1 (en) | 1996-08-21 | 1998-02-26 | Smithkline Beecham Corporation | Il-8 receptor antagonists |
US6559144B2 (en) | 1997-02-13 | 2003-05-06 | Merck Patent Gesellschaft Mit | Bicyclic amino acids |
ES2300119T3 (es) | 1997-02-27 | 2008-06-01 | Takeda Pharmaceutical Company Limited | Compuestos de amina, su produccion y su uso como inhibidores de la produccion de beta-amiloide. |
TWI242011B (en) | 1997-03-31 | 2005-10-21 | Eisai Co Ltd | 1,4-substituted cyclic amine derivatives |
FR2778662B1 (fr) | 1998-05-12 | 2000-06-16 | Adir | Nouveaux composes cycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
EP1136477B1 (de) | 1998-12-04 | 2004-03-10 | Takeda Chemical Industries, Ltd. | Benzofuranderivate, verfahren zu ihrer herstellung und deren verwendungen |
CN101058543B (zh) | 2000-04-03 | 2010-05-26 | 武田药品工业株式会社 | 制备胺衍生物的方法 |
AR035858A1 (es) | 2001-04-23 | 2004-07-21 | Bayer Corp | Derivados de cromano 2,6-sustituidos,composiciones farmaceuticas,uso de dichos derivados para la manufactura de medicamentos utiles como agonistas adrenorreceptores beta-3 |
CN1561338A (zh) * | 2001-10-04 | 2005-01-05 | 惠氏公司 | 作为5-羟基色胺-6配体的苯并二氢吡喃衍生物 |
WO2003029239A1 (en) | 2001-10-04 | 2003-04-10 | Wyeth | Chroman and benzofuran derivatives as 5-hydroxytryptamine-6 ligands |
PL211057B1 (pl) * | 2002-05-13 | 2012-04-30 | Hoffmann La Roche | Pochodne benzoksazyny, sposób ich wytwarzania, środek farmaceutyczny i zastosowanie pochodnych benzoksazyny |
US7943639B2 (en) | 2002-06-20 | 2011-05-17 | Proximagen Limited | Compounds |
WO2005037223A2 (en) | 2003-10-15 | 2005-04-28 | Brigham And Women's Hospital, Inc. | Methods and compositions for immunomodulation |
AU2004283313A1 (en) | 2003-10-24 | 2005-05-06 | Exelixis, Inc. | TAO kinase modulators and methods of use |
-
2005
- 2005-04-27 CA CA002566196A patent/CA2566196A1/en not_active Abandoned
- 2005-04-27 RU RU2006138180/04A patent/RU2372344C2/ru not_active IP Right Cessation
- 2005-04-27 BR BRPI0510642-7A patent/BRPI0510642A/pt not_active IP Right Cessation
- 2005-04-27 AU AU2005238179A patent/AU2005238179B2/en not_active Ceased
- 2005-04-27 ES ES05734404T patent/ES2338668T3/es active Active
- 2005-04-27 NZ NZ550441A patent/NZ550441A/en unknown
- 2005-04-27 AT AT05734404T patent/ATE458727T1/de not_active IP Right Cessation
- 2005-04-27 DE DE602005019562T patent/DE602005019562D1/de active Active
- 2005-04-27 CN CNB2005800143682A patent/CN100540546C/zh not_active Expired - Fee Related
- 2005-04-27 JP JP2007511952A patent/JP2007536302A/ja not_active Ceased
- 2005-04-27 KR KR1020067023073A patent/KR100823805B1/ko not_active IP Right Cessation
- 2005-04-27 EP EP05734404A patent/EP1748995B1/de active Active
- 2005-04-27 MX MXPA06012621A patent/MXPA06012621A/es active IP Right Grant
- 2005-04-27 WO PCT/EP2005/004479 patent/WO2005105776A1/en active Application Filing
- 2005-05-02 AR ARP050101740A patent/AR048936A1/es unknown
- 2005-05-03 TW TW094114308A patent/TWI298636B/zh not_active IP Right Cessation
- 2005-05-04 US US11/121,873 patent/US7368567B2/en not_active Expired - Fee Related
-
2006
- 2006-10-13 ZA ZA200608588A patent/ZA200608588B/en unknown
- 2006-10-23 IL IL178819A patent/IL178819A0/en unknown
- 2006-11-29 NO NO20065510A patent/NO20065510L/no not_active Application Discontinuation
-
2007
- 2007-09-05 HK HK07109656.9A patent/HK1104533A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU2005238179A1 (en) | 2005-11-10 |
WO2005105776A8 (en) | 2007-01-11 |
CN1960983A (zh) | 2007-05-09 |
CA2566196A1 (en) | 2005-11-10 |
ATE458727T1 (de) | 2010-03-15 |
MXPA06012621A (es) | 2006-12-15 |
US7368567B2 (en) | 2008-05-06 |
EP1748995A1 (de) | 2007-02-07 |
WO2005105776A1 (en) | 2005-11-10 |
JP2007536302A (ja) | 2007-12-13 |
CN100540546C (zh) | 2009-09-16 |
EP1748995B1 (de) | 2010-02-24 |
HK1104533A1 (en) | 2008-01-18 |
TWI298636B (en) | 2008-07-11 |
NZ550441A (en) | 2009-07-31 |
RU2372344C2 (ru) | 2009-11-10 |
US20050250943A1 (en) | 2005-11-10 |
ZA200608588B (en) | 2008-06-25 |
TW200605894A (en) | 2006-02-16 |
AU2005238179B2 (en) | 2010-08-26 |
RU2006138180A (ru) | 2008-06-10 |
KR20070009664A (ko) | 2007-01-18 |
IL178819A0 (en) | 2007-03-08 |
KR100823805B1 (ko) | 2008-04-21 |
NO20065510L (no) | 2007-01-12 |
ES2338668T3 (es) | 2010-05-11 |
BRPI0510642A (pt) | 2007-11-20 |
AR048936A1 (es) | 2006-06-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |