HK1104533A1 - Arylsulfonyl benzodioxanes useful for modulating the 5-ht6 receptor, the 5- ht2a receptor or both - Google Patents
Arylsulfonyl benzodioxanes useful for modulating the 5-ht6 receptor, the 5- ht2a receptor or bothInfo
- Publication number
- HK1104533A1 HK1104533A1 HK07109656.9A HK07109656A HK1104533A1 HK 1104533 A1 HK1104533 A1 HK 1104533A1 HK 07109656 A HK07109656 A HK 07109656A HK 1104533 A1 HK1104533 A1 HK 1104533A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- receptor
- benzodioxanes
- arylsulfonyl
- modulating
- useful
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
- C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
- C07D327/06—Six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Child & Adolescent Psychology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US56831404P | 2004-05-05 | 2004-05-05 | |
PCT/EP2005/004479 WO2005105776A1 (en) | 2004-05-05 | 2005-04-27 | Arylsulfonyl benzodioxanes useful for modulation the 5-ht6 receptor, the 5-ht2areceptor or both |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1104533A1 true HK1104533A1 (en) | 2008-01-18 |
Family
ID=34965191
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK07109656.9A HK1104533A1 (en) | 2004-05-05 | 2007-09-05 | Arylsulfonyl benzodioxanes useful for modulating the 5-ht6 receptor, the 5- ht2a receptor or both |
Country Status (21)
Country | Link |
---|---|
US (1) | US7368567B2 (de) |
EP (1) | EP1748995B1 (de) |
JP (1) | JP2007536302A (de) |
KR (1) | KR100823805B1 (de) |
CN (1) | CN100540546C (de) |
AR (1) | AR048936A1 (de) |
AT (1) | ATE458727T1 (de) |
AU (1) | AU2005238179B2 (de) |
BR (1) | BRPI0510642A (de) |
CA (1) | CA2566196A1 (de) |
DE (1) | DE602005019562D1 (de) |
ES (1) | ES2338668T3 (de) |
HK (1) | HK1104533A1 (de) |
IL (1) | IL178819A0 (de) |
MX (1) | MXPA06012621A (de) |
NO (1) | NO20065510L (de) |
NZ (1) | NZ550441A (de) |
RU (1) | RU2372344C2 (de) |
TW (1) | TWI298636B (de) |
WO (1) | WO2005105776A1 (de) |
ZA (1) | ZA200608588B (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2420318C2 (ru) * | 2004-09-30 | 2011-06-10 | Ф.Хоффманн-Ля Рош Аг | Композиции и способы для лечения когнитивных расстройств |
KR100965190B1 (ko) * | 2004-12-21 | 2010-06-24 | 에프. 호프만-라 로슈 아게 | 크로만 유도체 및 중추 신경계 장애의 치료에서 그의 용도 |
JP2008538575A (ja) * | 2005-04-22 | 2008-10-30 | ワイス | ベンゾジオキサンおよびベンゾジオキソラン誘導体ならびにそれらの使用 |
BRPI0618206A2 (pt) | 2005-11-03 | 2011-08-23 | Hoffmann La Roche | arilsulfonil cromanos como inibidores de 5-ht6, bem como composição farmacêutica, uso e processo para produção dos mesmos |
WO2007120596A1 (en) * | 2006-04-12 | 2007-10-25 | Wyeth | DIHYDRO[1,4]DIOXINO[2,3-e]INDAZOLE DERIVATIVES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS |
CA2654822A1 (en) * | 2006-06-20 | 2007-12-27 | F. Hoffmann-La Roche Ag | Arylsulfonyl naphthalene derivatives and uses thereof |
FR2913886B1 (fr) | 2007-03-22 | 2012-03-02 | Guerbet Sa | Utilisation de nanoparticules metalliques dans le diagnostique de la maladie d'alzheimer |
EP2271638B1 (de) | 2008-04-29 | 2011-08-31 | NSAB, Filial af NeuroSearch Sweden AB, Sverige | Modulatoren der dopamin-neurotransmission |
WO2009133109A1 (en) * | 2008-04-29 | 2009-11-05 | Nsab, Filial Af Neurosearch Sweden Ab, Sverige | Modulators of dopamine neurotransmission |
US8524766B2 (en) | 2008-04-29 | 2013-09-03 | Nsab, Filial Af Neurosearch Sweden Ab, Sverige | Modulators of dopamine neurotransmission |
CN114890978B (zh) * | 2022-04-19 | 2023-07-25 | 宿迁医美科技有限公司 | 酚类化合物及其制备方法和应用 |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
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DE3901814A1 (de) | 1988-07-28 | 1990-02-01 | Bayer Ag | Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga |
TW224941B (de) * | 1989-11-08 | 1994-06-11 | Yamanouchi Pharma Co Ltd | |
US5506192A (en) | 1990-06-07 | 1996-04-09 | Sandoz Ltd. | Substituted phthalides and heterocyclic phthalides |
CA2087859C (en) | 1990-07-27 | 2002-01-01 | Hiroshi Koga | Benzopyran derivatives |
US5401848A (en) | 1990-11-26 | 1995-03-28 | E. R. Squibb & Sons, Inc. | Indane and quinoline derivatives |
US5817693A (en) | 1991-11-05 | 1998-10-06 | Cousins; Russell Donovan | Endothelin receptor antagonists |
ZA93436B (en) | 1992-01-24 | 1993-08-25 | Chugai Pharmaceutical Co Ltd | Benzopyran derivatives |
WO1994004521A1 (en) | 1992-08-17 | 1994-03-03 | Chugai Seiyaku Kabushiki Kaisha | Benzopyran and benzoxazine derivatives |
US5374643A (en) | 1992-09-11 | 1994-12-20 | E. R. Squibb & Sons, Inc. | Aryl urea (thiourea) and cyanoguanidine derivatives |
GB9309716D0 (en) * | 1993-05-12 | 1993-06-23 | Zeneca Ltd | Heterocyclic derivatives |
US5739135A (en) | 1993-09-03 | 1998-04-14 | Bristol-Myers Squibb Company | Inhibitors of microsomal triglyceride transfer protein and method |
US6150402A (en) | 1994-08-15 | 2000-11-21 | Loma Linda University Medical Center | Natriuretic compounds |
US5869478A (en) | 1995-06-07 | 1999-02-09 | Bristol-Myers Squibb Company | Sulfonamido substituted benzopyran derivatives |
EP0836599A1 (de) | 1995-06-30 | 1998-04-22 | PHARMACIA & UPJOHN COMPANY | 1,6 disubstituierte isochromane für die behandlung von migränekopfschmerzen |
US5663194A (en) | 1995-07-25 | 1997-09-02 | Mewshaw; Richard E. | Chroman-2-ylmethylamino derivatives |
US5935958A (en) | 1996-07-01 | 1999-08-10 | Schering Corporation | Muscarinic antagonists |
WO1998007418A1 (en) | 1996-08-21 | 1998-02-26 | Smithkline Beecham Corporation | Il-8 receptor antagonists |
US6559144B2 (en) | 1997-02-13 | 2003-05-06 | Merck Patent Gesellschaft Mit | Bicyclic amino acids |
PT971878E (pt) | 1997-02-27 | 2008-07-08 | Takeda Pharmaceutical | Compostos de amina, sua produção e utilização como inibidores da produção de amilóide beta |
TWI242011B (en) | 1997-03-31 | 2005-10-21 | Eisai Co Ltd | 1,4-substituted cyclic amine derivatives |
FR2778662B1 (fr) | 1998-05-12 | 2000-06-16 | Adir | Nouveaux composes cycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
ES2213407T3 (es) | 1998-12-04 | 2004-08-16 | Takeda Chemical Industries, Ltd. | Derivados de benzofurano, procedimiento para su preparacion, y sus usos. |
ATE413379T1 (de) | 2000-04-03 | 2008-11-15 | Takeda Pharmaceutical | Verfahren zur herstellung von amin-derivaten |
AR035858A1 (es) | 2001-04-23 | 2004-07-21 | Bayer Corp | Derivados de cromano 2,6-sustituidos,composiciones farmaceuticas,uso de dichos derivados para la manufactura de medicamentos utiles como agonistas adrenorreceptores beta-3 |
WO2003029239A1 (en) | 2001-10-04 | 2003-04-10 | Wyeth | Chroman and benzofuran derivatives as 5-hydroxytryptamine-6 ligands |
CA2461381A1 (en) * | 2001-10-04 | 2003-04-10 | Wyeth | Chroman derivatives as 5-hydroxytryptamine-6 ligands |
UA76877C2 (uk) * | 2002-05-13 | 2006-09-15 | Ф.Хоффманн-Ля Рош Аг | Похідні бензоксазину як 5-нт6 модулятори і їх застосування |
JP4754821B2 (ja) | 2002-06-20 | 2011-08-24 | プロキシマゲン・リミテッド | 肥満症、ii型糖尿病およびcns障害の治療に有用な新規化合物 |
US7795242B2 (en) | 2003-10-15 | 2010-09-14 | The Brigham And Women's Hospital, Inc. | Methods and compositions for immunomodulation |
AU2004283313A1 (en) | 2003-10-24 | 2005-05-06 | Exelixis, Inc. | TAO kinase modulators and methods of use |
-
2005
- 2005-04-27 KR KR1020067023073A patent/KR100823805B1/ko not_active IP Right Cessation
- 2005-04-27 CA CA002566196A patent/CA2566196A1/en not_active Abandoned
- 2005-04-27 EP EP05734404A patent/EP1748995B1/de active Active
- 2005-04-27 MX MXPA06012621A patent/MXPA06012621A/es active IP Right Grant
- 2005-04-27 AT AT05734404T patent/ATE458727T1/de not_active IP Right Cessation
- 2005-04-27 NZ NZ550441A patent/NZ550441A/en unknown
- 2005-04-27 ES ES05734404T patent/ES2338668T3/es active Active
- 2005-04-27 WO PCT/EP2005/004479 patent/WO2005105776A1/en active Application Filing
- 2005-04-27 RU RU2006138180/04A patent/RU2372344C2/ru not_active IP Right Cessation
- 2005-04-27 JP JP2007511952A patent/JP2007536302A/ja not_active Ceased
- 2005-04-27 BR BRPI0510642-7A patent/BRPI0510642A/pt not_active IP Right Cessation
- 2005-04-27 DE DE602005019562T patent/DE602005019562D1/de active Active
- 2005-04-27 CN CNB2005800143682A patent/CN100540546C/zh not_active Expired - Fee Related
- 2005-04-27 AU AU2005238179A patent/AU2005238179B2/en not_active Ceased
- 2005-05-02 AR ARP050101740A patent/AR048936A1/es unknown
- 2005-05-03 TW TW094114308A patent/TWI298636B/zh not_active IP Right Cessation
- 2005-05-04 US US11/121,873 patent/US7368567B2/en not_active Expired - Fee Related
-
2006
- 2006-10-13 ZA ZA200608588A patent/ZA200608588B/en unknown
- 2006-10-23 IL IL178819A patent/IL178819A0/en unknown
- 2006-11-29 NO NO20065510A patent/NO20065510L/no not_active Application Discontinuation
-
2007
- 2007-09-05 HK HK07109656.9A patent/HK1104533A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR100823805B1 (ko) | 2008-04-21 |
TW200605894A (en) | 2006-02-16 |
NO20065510L (no) | 2007-01-12 |
JP2007536302A (ja) | 2007-12-13 |
ATE458727T1 (de) | 2010-03-15 |
NZ550441A (en) | 2009-07-31 |
AU2005238179A1 (en) | 2005-11-10 |
AU2005238179B2 (en) | 2010-08-26 |
ES2338668T3 (es) | 2010-05-11 |
CN1960983A (zh) | 2007-05-09 |
RU2006138180A (ru) | 2008-06-10 |
CA2566196A1 (en) | 2005-11-10 |
US7368567B2 (en) | 2008-05-06 |
EP1748995B1 (de) | 2010-02-24 |
EP1748995A1 (de) | 2007-02-07 |
TWI298636B (en) | 2008-07-11 |
DE602005019562D1 (de) | 2010-04-08 |
MXPA06012621A (es) | 2006-12-15 |
RU2372344C2 (ru) | 2009-11-10 |
BRPI0510642A (pt) | 2007-11-20 |
ZA200608588B (en) | 2008-06-25 |
CN100540546C (zh) | 2009-09-16 |
WO2005105776A1 (en) | 2005-11-10 |
AR048936A1 (es) | 2006-06-14 |
KR20070009664A (ko) | 2007-01-18 |
US20050250943A1 (en) | 2005-11-10 |
WO2005105776A8 (en) | 2007-01-11 |
IL178819A0 (en) | 2007-03-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
CHRG | Changes in the register |
Free format text: CORRECTION OF THE NAME OF APPLICANT FROM F. HOFFMANN-LA ROCHE TO F. HOFFMANN-LA ROCHE AG |
|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20140427 |