DE602005002847D1 - Thienopyridoncarbonsäureamide und deren medizinische verwendung - Google Patents

Thienopyridoncarbonsäureamide und deren medizinische verwendung

Info

Publication number
DE602005002847D1
DE602005002847D1 DE602005002847T DE602005002847T DE602005002847D1 DE 602005002847 D1 DE602005002847 D1 DE 602005002847D1 DE 602005002847 T DE602005002847 T DE 602005002847T DE 602005002847 T DE602005002847 T DE 602005002847T DE 602005002847 D1 DE602005002847 D1 DE 602005002847D1
Authority
DE
Germany
Prior art keywords
hydrogen
methyl
fluoro
chloro
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005002847T
Other languages
English (en)
Other versions
DE602005002847T2 (de
Inventor
Anders Bjoerk
Karl Jansson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Active Biotech AB
Original Assignee
Active Biotech AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Active Biotech AB filed Critical Active Biotech AB
Publication of DE602005002847D1 publication Critical patent/DE602005002847D1/de
Application granted granted Critical
Publication of DE602005002847T2 publication Critical patent/DE602005002847T2/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE602005002847T 2004-06-18 2005-06-15 Thienopyridoncarbonsäureamide und deren medizinische verwendung Active DE602005002847T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0401578A SE0401578D0 (sv) 2004-06-18 2004-06-18 Novel compounds
SE0401578 2004-06-18
PCT/EP2005/052767 WO2005123744A1 (en) 2004-06-18 2005-06-15 Thienopyridone carboxamides and their medical use

Publications (2)

Publication Number Publication Date
DE602005002847D1 true DE602005002847D1 (de) 2007-11-22
DE602005002847T2 DE602005002847T2 (de) 2008-07-10

Family

ID=32906817

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005002847T Active DE602005002847T2 (de) 2004-06-18 2005-06-15 Thienopyridoncarbonsäureamide und deren medizinische verwendung

Country Status (13)

Country Link
US (1) US7553849B2 (de)
EP (1) EP1776369B1 (de)
JP (1) JP4906718B2 (de)
CN (1) CN1980937B (de)
AT (1) ATE375353T1 (de)
AU (1) AU2005254731B2 (de)
CA (1) CA2570506C (de)
DE (1) DE602005002847T2 (de)
ES (1) ES2294721T3 (de)
RU (1) RU2374250C2 (de)
SE (1) SE0401578D0 (de)
WO (1) WO2005123744A1 (de)
ZA (1) ZA200609265B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112013007850A2 (pt) * 2010-10-14 2016-06-07 Immunahr Ab 1,2-diidro-4-hidróxi-2-oxo-quinolina-3-carboxanilidas como ativadores de ahr
CN102127091B (zh) * 2010-12-30 2012-11-21 天津药物研究院 含有杂环的希夫碱化合物
EP3904357A4 (de) * 2018-11-20 2022-08-03 The National Institutes of Pharmaceutical R&D Co., Ltd Spiro-verbindung und medizinische verwendung davon
CN114957278B (zh) * 2021-02-20 2023-08-11 兰州大学 胰高血糖素受体拮抗剂及其用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5219864A (en) * 1991-03-12 1993-06-15 Kyowa Hakko Kogyo Co., Ltd. Thienopyridine derivatives
DE4227747A1 (de) * 1992-08-21 1994-02-24 Basf Ag Heteroaromatisch kondensierte Hydroxypyridoncarbonsäureamide, deren Herstellung und Verwendung
GB9311562D0 (en) * 1993-06-04 1993-07-21 Fujisawa Pharmaceutical Co Heterocyclic derivatives
SE9801474D0 (sv) * 1998-04-27 1998-04-27 Active Biotech Ab Quinoline Derivatives
SE9802549D0 (sv) * 1998-07-15 1998-07-15 Active Biotech Ab Quinoline derivatives
SE9802550D0 (sv) * 1998-07-15 1998-07-15 Active Biotech Ab Quinoline derivatives
DK1159279T3 (da) 1999-03-09 2003-02-17 Upjohn Co 4-Oxo-4,7-dihydro-thieno[2,3-b]pyridin-5-carboxamider som antivirale midler
SE0002320D0 (sv) * 1999-10-25 2000-06-21 Active Biotech Ab Malignant tumors
PT1419772E (pt) 2001-08-24 2007-09-05 Dynogen Pharmaceuticals Inc Agente preventivo/agente terapêutico papa ibs com predominância de obstipação.
AR038294A1 (es) 2002-01-14 2005-01-12 Upjohn Co Oxotieno(3,2-b)piridincarboxamidas como agentes antivirales
WO2004019939A1 (en) 2002-08-30 2004-03-11 Pharmacia & Upjohn Company Method of preventing or treating atherosclerosis or restenosis

Also Published As

Publication number Publication date
US7553849B2 (en) 2009-06-30
US20060004038A1 (en) 2006-01-05
DE602005002847T2 (de) 2008-07-10
JP2008502655A (ja) 2008-01-31
CN1980937A (zh) 2007-06-13
RU2007101702A (ru) 2008-07-27
JP4906718B2 (ja) 2012-03-28
AU2005254731A1 (en) 2005-12-29
EP1776369B1 (de) 2007-10-10
ES2294721T3 (es) 2008-04-01
ZA200609265B (en) 2008-05-28
RU2374250C2 (ru) 2009-11-27
WO2005123744A1 (en) 2005-12-29
AU2005254731B2 (en) 2010-10-21
CA2570506C (en) 2012-12-18
CN1980937B (zh) 2011-08-10
ATE375353T1 (de) 2007-10-15
CA2570506A1 (en) 2005-12-29
SE0401578D0 (sv) 2004-06-18
EP1776369A1 (de) 2007-04-25

Similar Documents

Publication Publication Date Title
MX2009002229A (es) Benzotriazoles como moduladores de cinasas.
ATE537830T1 (de) Nicotinamid derivate und ihre verwendung als therapeutika
YU1501A (sh) Derivati hinolina
NO20071921L (no) Fremgangsmater for behandling av epileptogenese og epilepsi
ECSP088179A (es) Compuestos de carbamato para usarse en el tratamiento de desordenes neurodegenerativos
NO20080877L (no) Fremgangsmater for behandling av substansrelaterte forstyrrelser
CY1110145T1 (el) Αλκυλο-υποκατεστημενες ινδολοκινοξαλινες
RS49590B (sr) Upotreba inhibitora h+,k+-atpaze za proizvodnju novih farmaceutskih preparata
TW200744575A (en) Methods of treating epileptogenesis
MY157373A (en) Carbamate compounds for use in preventing or treating movement disorders
DE602005002847D1 (de) Thienopyridoncarbonsäureamide und deren medizinische verwendung
DE602007011434D1 (de) 1h-indol-5-ylpiperazin-1-ylmethanonderivate
NO20033802L (no) Karbamatforbindelser for anvendelse ved forebygging eller behandling av bipolar forstyrrelse
EA200700871A1 (ru) Способы нейропротекции
MX2009004553A (es) Metodos para el tratamiento de trastornos cocleares y vestibulares.
NO20033800L (no) Karbamidforbindelser for bruk ved prevensjon eller terapi av angstlidelser
MXPA02011464A (es) Derivados 1,4-diazepan-2,5-diona y su uso como antagonistas del receptor de la nk-1.
RS67503A (en) Carbamate compounds for use in preventing of treating psychotic disorders
DE60231568D1 (de) Verwendung von Pyrrolederivaten gegen Angstzustände
ATE356805T1 (de) Oxophenylcyclohexylpropanolaminderivate, deren herstellung und verwendung in therapeutika
ATE276256T1 (de) Ascidideminderivate und ihre therapeutische verwendung
MY136733A (en) Carbamate compounds for use in preventing or treating psychotic disorders
TH70879A (th) อนุพันธ์ของ 5-(ไพริดิน-3-อิล)-1-แอซาไบไซโคล[3.2.1]ออกเทน, การเตรียมสาร และการประยุกต์ใช้สารในการบำบัดรักษา
SE0401308D0 (sv) Anordning för lampanslutning
TW200614991A (en) Novel compounds

Legal Events

Date Code Title Description
8364 No opposition during term of opposition