DE60142329D1 - Ein verfahren zur herstellung von cephalosporin-derivaten unter verwendung von thiazolverbindungen - Google Patents

Ein verfahren zur herstellung von cephalosporin-derivaten unter verwendung von thiazolverbindungen

Info

Publication number
DE60142329D1
DE60142329D1 DE60142329T DE60142329T DE60142329D1 DE 60142329 D1 DE60142329 D1 DE 60142329D1 DE 60142329 T DE60142329 T DE 60142329T DE 60142329 T DE60142329 T DE 60142329T DE 60142329 D1 DE60142329 D1 DE 60142329D1
Authority
DE
Germany
Prior art keywords
preparation
cephalosporin derivatives
thiazol compounds
thiazol
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60142329T
Other languages
English (en)
Inventor
Dae Chul Yoon
Seung Won Yoo
Dong Gyun Shin
Myoung Ki Lee
Mi Soon Park
Yoon Seok Lee
Yoon Seok Song
Ju Cheol Lee
Sang Mi Oh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hanmi Fine Chemicals Co Ltd
Original Assignee
Hanmi Fine Chemicals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hanmi Fine Chemicals Co Ltd filed Critical Hanmi Fine Chemicals Co Ltd
Application granted granted Critical
Publication of DE60142329D1 publication Critical patent/DE60142329D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
DE60142329T 2000-03-20 2001-03-07 Ein verfahren zur herstellung von cephalosporin-derivaten unter verwendung von thiazolverbindungen Expired - Lifetime DE60142329D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2000-0014076A KR100392409B1 (ko) 2000-03-20 2000-03-20 신규한 티아졸 화합물을 이용한 세팔로스포린계항생물질의 제조 방법
PCT/KR2001/000347 WO2001070749A1 (en) 2000-03-20 2001-03-07 A process for preparing cephalosporin derivatives using new thiazole compound

Publications (1)

Publication Number Publication Date
DE60142329D1 true DE60142329D1 (de) 2010-07-22

Family

ID=19656811

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60142329T Expired - Lifetime DE60142329D1 (de) 2000-03-20 2001-03-07 Ein verfahren zur herstellung von cephalosporin-derivaten unter verwendung von thiazolverbindungen

Country Status (6)

Country Link
US (1) US6384212B1 (de)
EP (1) EP1268488B1 (de)
JP (1) JP3927808B2 (de)
KR (1) KR100392409B1 (de)
DE (1) DE60142329D1 (de)
WO (1) WO2001070749A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100392409B1 (ko) * 2000-03-20 2003-07-22 한미정밀화학주식회사 신규한 티아졸 화합물을 이용한 세팔로스포린계항생물질의 제조 방법
ITMI20012364A1 (it) * 2001-11-09 2003-05-09 Antibioticos Spa Processo di sintesi della cefixima via alchil-o arilsolfonati
DE602005012866D1 (de) * 2004-12-21 2009-04-02 Lupin Ltd Verfahren zur hestellung von cefixim
CN1312158C (zh) * 2005-05-20 2007-04-25 天津市医药集团技术发展有限公司 一种头孢克肟的制备方法
CN102516262A (zh) * 2011-12-20 2012-06-27 浙江国邦药业有限公司 一种头孢克肟三水合物的结晶方法
WO2016142902A1 (en) * 2015-03-11 2016-09-15 Lupin Limited Cefixime with reduced surface area and high stability
CN104892638B (zh) * 2015-05-28 2017-08-01 齐鲁安替制药有限公司 一锅法制备头孢他啶的方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR229883A1 (es) 1978-05-26 1983-12-30 Glaxo Group Ltd Procedimiento para la preparacion de antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)-acetamido)-3-(1-piridinometil)-cef-3-em-4-carboxilato
ZA803093B (en) 1979-05-25 1981-07-29 Glaxo Group Ltd Intermediates for use in the preparation of cephalosporin antibiotics
US4409214A (en) 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
KR840001827B1 (ko) 1980-07-14 1984-10-22 후지사와 야꾸힝 고오교오 가부시기 가이샤 7-아실아미노-3-비닐세팔로스포란산 유도체의 제조방법
JPS5877886A (ja) * 1981-11-02 1983-05-11 Toyama Chem Co Ltd 新規セフアロスポリン類
DE3375013D1 (en) * 1982-04-29 1988-02-04 Glaxo Group Ltd Thiazole derivative, process for its preparation and use in the preparation of beta-lactam antibiotics
JPS60208986A (ja) * 1984-03-31 1985-10-21 Toyama Chem Co Ltd 新規セファロスポリン類およびその製造法
JPH0662635B2 (ja) * 1984-04-26 1994-08-17 富山化学工業株式会社 セフアロスポリン類の新規製造法
KR870001807B1 (ko) 1985-09-07 1987-10-13 주식회사 종근당 3-비닐 세팔로 스포린 유도체의 제조방법
GB8611823D0 (en) * 1986-05-15 1986-06-25 Ici Plc Process
GB8800295D0 (en) * 1988-01-07 1988-02-10 Fujisawa Pharmaceutical Co Process for preparation of 7-(2-amino-thiazol-4-y)-2-hydroxyimino-acetanidol-3-cephem compounds
KR930007810B1 (ko) 1991-05-04 1993-08-20 주식회사 중외제약 7-아실아미노-3-비닐 세파로스포라닉에시드의 제조방법
US5587372A (en) * 1991-12-12 1996-12-24 Roussel Uclaf Cephalosporins
KR100257129B1 (ko) * 1993-09-11 2000-05-15 성재갑 신규 세팔로스포린계 항생제 및 이의 제조방법
KR0127113B1 (ko) 1994-01-28 1998-04-01 임성기 3-비닐세펨 유도체의 제조방법
TW538045B (en) 1997-01-16 2003-06-21 Biochemie Gmbh Process for purifying cefixime
KR100342600B1 (ko) * 2000-03-06 2002-07-04 한미정밀화학주식회사 신규한 티아졸 화합물 및 그의 제조 방법
KR100392409B1 (ko) * 2000-03-20 2003-07-22 한미정밀화학주식회사 신규한 티아졸 화합물을 이용한 세팔로스포린계항생물질의 제조 방법
JP2004149412A (ja) * 2000-06-21 2004-05-27 Fujisawa Pharmaceut Co Ltd ７−［２−（２−アミノチアゾール−４−イル）−２−低級アルコキシカルボニルメトキシイミノアセトアミド］−３−セフェム化合物の製造法

Also Published As

Publication number Publication date
JP2003528105A (ja) 2003-09-24
KR20010092130A (ko) 2001-10-24
EP1268488B1 (de) 2010-06-09
WO2001070749A1 (en) 2001-09-27
US6384212B1 (en) 2002-05-07
EP1268488A1 (de) 2003-01-02
KR100392409B1 (ko) 2003-07-22
JP3927808B2 (ja) 2007-06-13
EP1268488A4 (de) 2004-02-04

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