DE60134640D1 - Verfahren zur herstellung von mikropartikeln mit einem ausgewählten polymermolekulargewicht - Google Patents

Verfahren zur herstellung von mikropartikeln mit einem ausgewählten polymermolekulargewicht

Info

Publication number
DE60134640D1
DE60134640D1 DE60134640T DE60134640T DE60134640D1 DE 60134640 D1 DE60134640 D1 DE 60134640D1 DE 60134640 T DE60134640 T DE 60134640T DE 60134640 T DE60134640 T DE 60134640T DE 60134640 D1 DE60134640 D1 DE 60134640D1
Authority
DE
Germany
Prior art keywords
molecular weight
weight
polymermolekular
polymer
producing microparticles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60134640T
Other languages
English (en)
Inventor
Steven G Wright
Michael E Rickey
J Michael Ramstack
Shawn L Lyons
Joyce M Hotz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alkermes Inc
Original Assignee
Alkermes Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24298824&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60134640(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alkermes Inc filed Critical Alkermes Inc
Application granted granted Critical
Publication of DE60134640D1 publication Critical patent/DE60134640D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polyamides (AREA)
DE60134640T 2000-05-19 2001-04-19 Verfahren zur herstellung von mikropartikeln mit einem ausgewählten polymermolekulargewicht Expired - Lifetime DE60134640D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/575,075 US6264987B1 (en) 2000-05-19 2000-05-19 Method for preparing microparticles having a selected polymer molecular weight
PCT/US2001/012654 WO2001089482A2 (en) 2000-05-19 2001-04-19 Method for preparing microparticles having a selected polymer molecular weight

Publications (1)

Publication Number Publication Date
DE60134640D1 true DE60134640D1 (de) 2008-08-14

Family

ID=24298824

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60134640T Expired - Lifetime DE60134640D1 (de) 2000-05-19 2001-04-19 Verfahren zur herstellung von mikropartikeln mit einem ausgewählten polymermolekulargewicht

Country Status (12)

Country Link
US (6) US6264987B1 (de)
EP (3) EP2258348A3 (de)
JP (1) JP4903344B2 (de)
AT (1) ATE399535T1 (de)
AU (2) AU5546501A (de)
CA (1) CA2405787C (de)
CY (2) CY1110403T1 (de)
DE (1) DE60134640D1 (de)
DK (2) DK1282404T3 (de)
ES (2) ES2391315T5 (de)
PT (2) PT1925297E (de)
WO (1) WO2001089482A2 (de)

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JP2003534268A (ja) 2003-11-18
CY1110403T1 (el) 2015-04-29
EP2258348A3 (de) 2011-10-05
US6379704B2 (en) 2002-04-30
US20030211164A1 (en) 2003-11-13
WO2001089482A2 (en) 2001-11-29
CA2405787C (en) 2011-06-14
ATE399535T1 (de) 2008-07-15
DK1282404T3 (da) 2008-09-01
DK1925297T3 (da) 2012-10-08
EP1282404B1 (de) 2008-07-02
DK1925297T4 (da) 2017-11-06
JP4903344B2 (ja) 2012-03-28
ES2391315T5 (es) 2017-12-20
ES2305071T3 (es) 2008-11-01
US20020001621A1 (en) 2002-01-03
PT1925297E (pt) 2012-10-18
CA2405787A1 (en) 2001-11-29
EP1282404A2 (de) 2003-02-12
AU2001255465B2 (en) 2004-09-23
US20020119203A1 (en) 2002-08-29
EP2258348A2 (de) 2010-12-08
EP1925297A1 (de) 2008-05-28
US20080058502A1 (en) 2008-03-06
WO2001089482A3 (en) 2002-02-21
EP1925297B2 (de) 2017-08-16
EP1925297B1 (de) 2012-07-11
US6264987B1 (en) 2001-07-24
ES2391315T3 (es) 2012-11-23
US20030143279A1 (en) 2003-07-31
PT1282404E (pt) 2008-07-16
CY1113082T1 (el) 2016-04-13

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