DE60128721D1 - Verfahren und vorrichtung zur fluoreszenzlumineszenzmessung - Google Patents

Verfahren und vorrichtung zur fluoreszenzlumineszenzmessung

Info

Publication number
DE60128721D1
DE60128721D1 DE60128721T DE60128721T DE60128721D1 DE 60128721 D1 DE60128721 D1 DE 60128721D1 DE 60128721 T DE60128721 T DE 60128721T DE 60128721 T DE60128721 T DE 60128721T DE 60128721 D1 DE60128721 D1 DE 60128721D1
Authority
DE
Germany
Prior art keywords
luminescence measurement
fluorescence luminescence
fluorescence
measurement
luminescence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60128721T
Other languages
English (en)
Other versions
DE60128721T2 (de
Inventor
Takami Shibazaki
Kaneyasu Okawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Olympus Corp
Original Assignee
Olympus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Olympus Corp filed Critical Olympus Corp
Publication of DE60128721D1 publication Critical patent/DE60128721D1/de
Application granted granted Critical
Publication of DE60128721T2 publication Critical patent/DE60128721T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Materials By The Use Of Optical Means Adapted For Particular Applications (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Photometry And Measurement Of Optical Pulse Characteristics (AREA)
DE60128721T 2000-12-26 2001-11-16 Verfahren und vorrichtung zur fluoreszenzlumineszenzmessung Expired - Lifetime DE60128721T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2000395882 2000-12-26
JP2000395882 2000-12-26
JP2001342190A JP3576523B2 (ja) 2000-12-26 2001-11-07 蛍光輝度測定方法及び装置
JP2001342190 2001-11-07
PCT/JP2001/010029 WO2002057756A1 (fr) 2000-12-26 2001-11-16 Procede et dispositif servant a mesurer la luminance de fluorescence

Publications (2)

Publication Number Publication Date
DE60128721D1 true DE60128721D1 (de) 2007-07-12
DE60128721T2 DE60128721T2 (de) 2008-01-24

Family

ID=26606717

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60128721T Expired - Lifetime DE60128721T2 (de) 2000-12-26 2001-11-16 Verfahren und vorrichtung zur fluoreszenzlumineszenzmessung

Country Status (6)

Country Link
US (1) US7224826B2 (de)
EP (1) EP1347285B1 (de)
JP (1) JP3576523B2 (de)
CN (1) CN1243231C (de)
DE (1) DE60128721T2 (de)
WO (1) WO2002057756A1 (de)

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JP4481082B2 (ja) * 2004-05-24 2010-06-16 オリンパス株式会社 顕微鏡観察方法および顕微鏡観察装置
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EP1912060A1 (de) * 2005-07-29 2008-04-16 Olympus Corporation Verfahren und vorrichtung zur messung von lichtintensität
JP4955244B2 (ja) 2005-09-27 2012-06-20 横河電機株式会社 バイオチップ読み取り装置およびバイオチップ読み取り方法
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JP4864519B2 (ja) * 2006-04-11 2012-02-01 浜松ホトニクス株式会社 光測定装置、光測定方法、及び光測定プログラム
JP5021254B2 (ja) * 2006-09-06 2012-09-05 オリンパス株式会社 顕微鏡装置の制御方法、顕微鏡装置
US8335360B2 (en) 2007-05-14 2012-12-18 Historx, Inc. Compartment segregation by pixel characterization using image data clustering
WO2008156669A1 (en) * 2007-06-15 2008-12-24 Historx, Inc. Method and system for standardizing microscope instruments
CA2604317C (en) 2007-08-06 2017-02-28 Historx, Inc. Methods and system for validating sample images for quantitative immunoassays
CA2596204C (en) 2007-08-07 2019-02-26 Historx, Inc. Method and system for determining an optimal dilution of a reagent
JP4979516B2 (ja) * 2007-08-31 2012-07-18 三菱レイヨン株式会社 画像読み取り方法および装置
DE102009006364A1 (de) * 2008-02-08 2009-09-10 Yokogawa Electric Corporation, Musashino Instrument zur Molekularitätsmessung und Verfahren zur Molekularitätsmessung
JP5407015B2 (ja) 2008-07-10 2014-02-05 国立大学法人徳島大学 画像処理装置、画像処理方法、コンピュータ実行可能な画像処理プログラム、及び顕微鏡システム
ES2573945T3 (es) 2008-09-16 2016-06-13 Novartis Ag Cuantificación reproducible de expresión de biomarcadores
US20110052446A1 (en) * 2009-08-31 2011-03-03 Life Technologies Corporation Flow cells and methods of filling and using same
GB201014016D0 (en) * 2010-08-20 2010-10-06 Synoptics Ltd Imaging system and associated method for detection of protein contamination
US9488922B2 (en) * 2010-12-06 2016-11-08 Asml Netherlands B.V. Methods and apparatus for inspection of articles, EUV lithography reticles, lithography apparatus and method of manufacturing devices
WO2012082464A2 (en) 2010-12-14 2012-06-21 Life Technologies Corporation Systems and methods for run-time sequencing run quality monitoring
DE102011018725A1 (de) * 2011-04-20 2012-10-25 Carl Zeiss Jena Gmbh Optische Anordnung zur Erfassung der Lumineszenz von Proben
US10190986B2 (en) * 2011-06-06 2019-01-29 Abbott Laboratories Spatially resolved ligand-receptor binding assays
CN102595051B (zh) * 2012-03-16 2014-10-22 盛司潼 一种基因测序图像的自动曝光的方法
EP2841927B1 (de) * 2012-04-27 2018-01-17 Bio-rad Laboratories, Inc. Farbung-freie proteinquantifizierung und normalisierung
JP6032837B2 (ja) * 2012-08-24 2016-11-30 株式会社システムロード 分析装置
JP6371686B2 (ja) * 2014-11-21 2018-08-08 富士フイルム株式会社 観察対象抽出処理装置、方法およびプログラム並びに観察画像撮像表示システム
EP3191885B1 (de) * 2015-03-19 2022-08-17 Koninklijke Philips N.V. Beleuchtung in digitaler pathologieabtastung
WO2017001526A1 (en) * 2015-06-30 2017-01-05 Imec Vzw Quantification of topologically arranged luminescent dyes
JP7039261B2 (ja) * 2017-11-17 2022-03-22 株式会社日立製作所 組織切片の特定領域からの生体分子採取方法および装置
JP6587709B2 (ja) * 2018-04-06 2019-10-09 富士フイルム株式会社 観察対象抽出処理装置、方法およびプログラム並びに観察画像撮像表示システム
DE102019204843A1 (de) * 2018-04-06 2019-10-10 Virtek Vision International Ulc Erkennen von Fluoreszenz von Fremdmaterial
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JP2023519489A (ja) * 2020-02-21 2023-05-11 サージビジョン・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 対応する補助画像内で識別される制限情報領域で処理された発光画像を用いた医療処置の支援
EP4033275A4 (de) * 2020-11-30 2023-10-25 Sol Inc. Fluoreszenzfilter und diesen enthaltendes bildsensormodul
CN113160074A (zh) * 2021-03-30 2021-07-23 广州万孚倍特生物技术有限公司 微阵列芯片图像分析方法、装置、计算机设备和存储介质
CN113340417B (zh) * 2021-04-25 2023-08-22 中国工程物理研究院应用电子学研究所 一种毫米波波束功率密度分布测量装置及测量方法

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Also Published As

Publication number Publication date
US7224826B2 (en) 2007-05-29
WO2002057756A1 (fr) 2002-07-25
DE60128721T2 (de) 2008-01-24
EP1347285B1 (de) 2007-05-30
EP1347285A4 (de) 2005-06-08
CN1483142A (zh) 2004-03-17
US20040001196A1 (en) 2004-01-01
CN1243231C (zh) 2006-02-22
JP3576523B2 (ja) 2004-10-13
JP2002257730A (ja) 2002-09-11
EP1347285A1 (de) 2003-09-24

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Legal Events

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