DE60121574D1 - Festes dispersionssystem von pranlukast mit verbesserter auflösung und methode zu dessen herstellung - Google Patents

Festes dispersionssystem von pranlukast mit verbesserter auflösung und methode zu dessen herstellung

Info

Publication number
DE60121574D1
DE60121574D1 DE60121574T DE60121574T DE60121574D1 DE 60121574 D1 DE60121574 D1 DE 60121574D1 DE 60121574 T DE60121574 T DE 60121574T DE 60121574 T DE60121574 T DE 60121574T DE 60121574 D1 DE60121574 D1 DE 60121574D1
Authority
DE
Germany
Prior art keywords
pranlucast
production
solid dispersion
dispersion system
improved resolution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60121574T
Other languages
English (en)
Other versions
DE60121574T2 (de
Inventor
Sang Deuk Lee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioinfra Co Ltd Suwon-City Gyunggi Kr
Original Assignee
Pegsphere Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pegsphere Co Ltd filed Critical Pegsphere Co Ltd
Application granted granted Critical
Publication of DE60121574D1 publication Critical patent/DE60121574D1/de
Publication of DE60121574T2 publication Critical patent/DE60121574T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Otolaryngology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DE60121574T 2000-05-20 2001-05-17 Festes dispersionssystem von pranlukast mit verbesserter auflösung und methode zu dessen herstellung Expired - Lifetime DE60121574T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2000-0027237A KR100381834B1 (ko) 2000-05-20 2000-05-20 용출성이 개선된 프란루카스트 고체분산체 조성물 및 그제조 방법
KR2000027237 2000-05-20
PCT/KR2001/000804 WO2001089574A1 (en) 2000-05-20 2001-05-17 Solid dispersion system of pranlukast with improved dissolution, and the preparing method thereof

Publications (2)

Publication Number Publication Date
DE60121574D1 true DE60121574D1 (de) 2006-08-31
DE60121574T2 DE60121574T2 (de) 2007-06-21

Family

ID=36794425

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60121574T Expired - Lifetime DE60121574T2 (de) 2000-05-20 2001-05-17 Festes dispersionssystem von pranlukast mit verbesserter auflösung und methode zu dessen herstellung

Country Status (9)

Country Link
US (1) US20030077322A1 (de)
EP (1) EP1283725B1 (de)
JP (1) JP3967924B2 (de)
KR (1) KR100381834B1 (de)
CN (1) CN1210065C (de)
AU (1) AU2001260727A1 (de)
CA (1) CA2405459A1 (de)
DE (1) DE60121574T2 (de)
WO (1) WO2001089574A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10350528A1 (de) * 2003-10-29 2005-06-09 Boehringer Ingelheim Pharma Gmbh & Co. Kg Arzneimittelformulierung, enthaltend einen LTB4-Antagonisten, sowie Verfahren zu deren Herstellung und deren Verwendung
KR20060125805A (ko) * 2003-11-18 2006-12-06 베링거 인겔하임 인터내셔날 게엠베하 고체 약제학적 제제 형태
EP1750669A1 (de) * 2004-05-04 2007-02-14 Boehringer Ingelheim International Gmbh Solide pharmazeutische form mit einem ltb4-antagonist
JP4742679B2 (ja) * 2004-05-27 2011-08-10 小野薬品工業株式会社 固形製剤用組成物
JP2006206612A (ja) * 2004-05-27 2006-08-10 Ono Pharmaceut Co Ltd 固形製剤用組成物
JP2007223903A (ja) * 2004-07-09 2007-09-06 Takeda Chem Ind Ltd 新規な固体分散体およびその製造方法
ATE481968T1 (de) * 2004-07-14 2010-10-15 Inflammation Res Ct Company Lt Verfahren zur hemmung von tumormetastasierung
KR101086254B1 (ko) * 2004-11-04 2011-11-24 에스케이케미칼주식회사 생체이용률이 개선된 프란루카스트 고체분산체 조성물 및그 고체분산체의 제조방법
KR101233235B1 (ko) * 2005-08-26 2013-02-15 에스케이케미칼주식회사 초기 용출율이 개선된 프란루카스트 고체분산체의 약제학적조성물 및 그의 제조방법
JP4870402B2 (ja) * 2005-09-01 2012-02-08 小林化工株式会社 プランルカスト水和物含有錠の製造方法
KR100715355B1 (ko) 2005-09-30 2007-05-07 주식회사유한양행 프란루카스트를 함유하는 분무-건조 과립 및 그의 제조방법
KR100981751B1 (ko) * 2005-10-28 2010-09-10 주식회사유한양행 프란루카스트를 함유하는 과립 및 그의 제조방법
KR100981750B1 (ko) 2005-10-28 2010-09-10 주식회사유한양행 분무-건조 과립 및 그의 제조방법
CN103313703A (zh) * 2010-12-27 2013-09-18 富田制药株式会社 制剂用崩解型核粒子
CN102178647B (zh) * 2011-04-28 2012-09-12 重庆圣华曦药物研究开发有限公司 普仑司特注射制剂
KR101378951B1 (ko) * 2011-07-29 2014-03-31 재단법인 유타 인하 디디에스 및 신의료기술개발 공동연구소 생체이용률이 향상된 초산 메게스트롤 분말을 포함하는 경구투여용 제제 및 이의 제조방법
CN103751108A (zh) * 2013-12-31 2014-04-30 北京万全德众医药生物技术有限公司 普仑司特固体分散体及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5876760A (en) * 1995-06-12 1999-03-02 Ono Pharmaceutical Co., Ltd. Granules containing pranlukast, process for producing the granules, and method of improving adhesiveness of pranlukast
US6503537B2 (en) * 1997-03-20 2003-01-07 Schering Corporation Preparation of powder agglomerates
TW546151B (en) * 1997-07-23 2003-08-11 Senju Pharma Co Aqueous liquid pharmaceutical composition containing as main component benzopyran derivative
US6224907B1 (en) * 1998-03-06 2001-05-01 Alza Corporation Anti-asthma therapy
US6267985B1 (en) * 1999-06-30 2001-07-31 Lipocine Inc. Clear oil-containing pharmaceutical compositions
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US6383471B1 (en) * 1999-04-06 2002-05-07 Lipocine, Inc. Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents

Also Published As

Publication number Publication date
JP3967924B2 (ja) 2007-08-29
EP1283725B1 (de) 2006-07-19
US20030077322A1 (en) 2003-04-24
CN1430521A (zh) 2003-07-16
KR100381834B1 (ko) 2003-04-26
JP2003534296A (ja) 2003-11-18
KR20010106006A (ko) 2001-11-29
WO2001089574A1 (en) 2001-11-29
DE60121574T2 (de) 2007-06-21
AU2001260727A1 (en) 2001-12-03
EP1283725A1 (de) 2003-02-19
CA2405459A1 (en) 2001-11-29
CN1210065C (zh) 2005-07-13
EP1283725A4 (de) 2003-06-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: BIOINFRA CO., LTD., SUWON-CITY, GYUNGGI, KR