DE60119945T2 - VERFAHREN ZUR THERAPIE VON B-ZELLMALIGNITÄTEN UNTER VERWENDUNG VON ANTAGONISTISCHEN ANTI-CD40-Antikörpern - Google Patents
VERFAHREN ZUR THERAPIE VON B-ZELLMALIGNITÄTEN UNTER VERWENDUNG VON ANTAGONISTISCHEN ANTI-CD40-Antikörpern Download PDFInfo
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Landscapes
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| US23755600P | 2000-10-02 | 2000-10-02 | |
| US237556P | 2000-10-02 | ||
| PCT/US2001/030963 WO2002028481A2 (en) | 2000-10-02 | 2001-10-02 | Methods of therapy for b-cell malignancies using antagonist anti-cd40 antibodies |
Publications (2)
| Publication Number | Publication Date |
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| DE60119945D1 DE60119945D1 (de) | 2006-06-29 |
| DE60119945T2 true DE60119945T2 (de) | 2007-01-18 |
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| DE60143535T Expired - Lifetime DE60143535D1 (de) | 2000-10-02 | 2001-10-02 | Humane antikörper gegen cd40 |
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| US7063845B2 (en) | 2000-04-28 | 2006-06-20 | Gemini Science, Inc. | Human anti-CD40 antibodies |
| JP4271440B2 (ja) * | 2000-10-02 | 2009-06-03 | ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド | ヒト抗ｃｄ４０抗体 |
| US7507724B2 (en) * | 2001-01-16 | 2009-03-24 | Sloan-Kettering Institute For Cancer Research | Therapy-enhancing glucan |
| US7906492B2 (en) | 2001-01-16 | 2011-03-15 | Sloan-Kettering Institute For Cancer Research | Therapy-enhancing glucan |
| ATE374214T1 (de) | 2001-04-27 | 2007-10-15 | Kirin Brewery | Monoklonaler anti-cd-40-antikörper |
| EP2236172A1 (en) * | 2003-11-04 | 2010-10-06 | Novartis Vaccines and Diagnostics, Inc. | Combination therapy comprising anti-CD20 and anti-CD40 antibodies for the treatment of B cell-related cancers |
| EP2301575A1 (en) * | 2003-11-04 | 2011-03-30 | Novartis Vaccines and Diagnostics, Inc. | Methods of therapy for solid tumors expressing the CD40 cell-surface antigen |
| DK2149585T3 (da) * | 2003-11-04 | 2013-10-21 | Novartis Vaccines & Diagnostic | Anvendelse af antagonistiske anti-CD40-monoklonale antistoffer |
| PT1682177E (pt) * | 2003-11-04 | 2010-11-29 | Xoma Technology Lt | Utilização de anticorpos antagonistas anti-cd40 para o tratamento da leucemia linfocítica crónica |
| EP1684805B8 (en) * | 2003-11-04 | 2010-08-25 | Novartis Vaccines and Diagnostics, Inc. | Use of antagonist anti-cd40 monoclonal antibodies for treatment of multiple myeloma |
| US8277810B2 (en) | 2003-11-04 | 2012-10-02 | Novartis Vaccines & Diagnostics, Inc. | Antagonist anti-CD40 antibodies |
| US20050136055A1 (en) * | 2003-12-22 | 2005-06-23 | Pfizer Inc | CD40 antibody formulation and methods |
| US20070292439A1 (en) * | 2004-04-27 | 2007-12-20 | Novartis Vaccines And Diagnostics, Inc. | Antagonist Anti-Cd40 Monoclonal Antibodies and Methods for Their Use |
| CA2604036A1 (en) | 2005-04-09 | 2006-10-19 | Fusion Antibodies Limited | Cathepsin s antibody |
| WO2006125143A2 (en) * | 2005-05-18 | 2006-11-23 | Novartis Ag | Methods for diagnosis and treatment of proliferative disorders mediated by cd40 signaling |
| DK1889065T3 (da) | 2005-05-18 | 2013-09-02 | Xoma Technology Ltd | Metoder til diagnostisering og behandling af sygdomme med en autoimmun- og/eller inflammationskomponent |
| US8926979B2 (en) | 2005-11-01 | 2015-01-06 | Novartis Ag | Treatment of cancer or pre-malignant conditions using anti-CD40 antibodies |
| US8323644B2 (en) * | 2006-01-17 | 2012-12-04 | Sloan-Kettering Institute For Cancer Research | Therapy-enhancing glucan |
| US20090053221A1 (en) * | 2006-01-17 | 2009-02-26 | Cheung Nai-Kong V | Immune response enhancing glucan |
| MEP39508A (en) | 2006-04-21 | 2011-02-10 | Novartis Ag | Antagonist anti-cd40 antibody pharmaceutical compositions |
| EP2589654A1 (en) | 2006-05-03 | 2013-05-08 | The Regents of the University of Colorado, a body corporate | CD40 agonist antibody/type1 interferon synergistic adjuvant combination, conjugates containing and use thereof as a therapeutic to enhance cellular immunity |
| US20090074711A1 (en) * | 2006-09-07 | 2009-03-19 | University Of Southhampton | Human therapies using chimeric agonistic anti-human cd40 antibody |
| DK2176298T3 (en) | 2007-05-30 | 2018-02-12 | Xencor Inc | Methods and compositions for inhibiting CD32B-expressing cells |
| EP2211902A1 (en) * | 2007-11-09 | 2010-08-04 | Novartis AG | Uses of anti-cd40 antibodies |
| EP2245065A1 (en) | 2008-01-23 | 2010-11-03 | Xencor, Inc. | Optimized cd40 antibodies and methods of using the same |
| WO2010104749A2 (en) | 2009-03-10 | 2010-09-16 | Baylor Research Institute | Antigen presenting cell targeted cancer vaccines |
| CN102770457A (zh) | 2009-03-10 | 2012-11-07 | 贝勒研究院 | 靶向抗原呈递细胞的疫苗 |
| BRPI1009455A2 (pt) | 2009-03-10 | 2016-03-01 | Baylor Res Inst | anticorpos anti-c40 e usos dos mesmos |
| WO2011109280A1 (en) | 2010-03-05 | 2011-09-09 | Lerner Research Institute | Methods and compositions to treat immune-mediated disorders |
| ES2993140T3 (en) | 2010-04-02 | 2024-12-23 | Amunix Pharmaceuticals Inc | Binding fusion proteins, binding fusion protein-drug conjugates, xten-drug conjugates and methods of making and using same |
| AR083847A1 (es) | 2010-11-15 | 2013-03-27 | Novartis Ag | Variantes de fc (fragmento constante) silenciosas de los anticuerpos anti-cd40 |
| WO2012075111A1 (en) | 2010-11-30 | 2012-06-07 | Novartis Ag | Uses of anti-cd40 antibodies in combination therapy for b cell-related cancers |
| PL3556774T3 (pl) | 2011-03-11 | 2024-07-01 | Beth Israel Deaconess Medical Center Inc. | Przeciwciała anty-cd40 i ich zastosowania |
| WO2012135132A1 (en) | 2011-03-25 | 2012-10-04 | Baylor Research Institute | Compositions and methods to immunize against hepatitis c virus |
| AU2012245309C1 (en) | 2011-04-21 | 2016-07-21 | Bristol-Myers Squibb Company | Antibody polypeptides that antagonize CD40 |
| WO2013072523A1 (en) | 2011-11-17 | 2013-05-23 | Gundram Jung | Bi-specific antibodies for medical use |
| JP2016011258A (ja) * | 2012-10-26 | 2016-01-21 | 株式会社ペルセウスプロテオミクス | 抗ヒトｃｄ４０モノクローナル抗体及びその利用 |
| JP6475631B2 (ja) | 2012-11-19 | 2019-02-27 | バリオファルム・アクチェンゲゼルシャフト | Ｃｄ２０およびｃｄ９５に結合する組換え二重特異性抗体 |
| US10286058B2 (en) | 2014-01-13 | 2019-05-14 | Baylor Research Institute | Vaccines against HPV and HPV-related diseases |
| US10435475B2 (en) | 2014-03-07 | 2019-10-08 | Bristol-Myers Squibb Company | Method of using antibody polypeptides that antagonize CD40 to treat IBD |
| KR20240073140A (ko) | 2014-10-29 | 2024-05-24 | 씨젠 인크. | 비-푸코실화된 항-cd40 항체의 용량 및 투여 |
| WO2016094679A1 (en) | 2014-12-10 | 2016-06-16 | Regents Of The University Of Minnesota | Genetically modified cells, tissues, and organs for treating disease |
| DK3303395T3 (da) | 2015-05-29 | 2020-01-27 | Abbvie Inc | Anti-cd40-antistoffer og anvendelser deraf |
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| IL263834B2 (en) | 2016-06-20 | 2024-01-01 | Kymab Ltd | Anti-pd-l1 antibodies |
| KR20250097987A (ko) | 2016-07-14 | 2025-06-30 | 젠맵 에이/에스 | Cd40 및 cd137에 대한 다중특이적 항체 |
| EP4252629A3 (en) | 2016-12-07 | 2023-12-27 | Biora Therapeutics, Inc. | Gastrointestinal tract detection methods, devices and systems |
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