DE60117584T2 - Verwendung von einem ppar-delta aktivator zur behandlung von entzündlichen zuständen - Google Patents
Verwendung von einem ppar-delta aktivator zur behandlung von entzündlichen zuständen Download PDFInfo
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- DE60117584T2 DE60117584T2 DE60117584T DE60117584T DE60117584T2 DE 60117584 T2 DE60117584 T2 DE 60117584T2 DE 60117584 T DE60117584 T DE 60117584T DE 60117584 T DE60117584 T DE 60117584T DE 60117584 T2 DE60117584 T2 DE 60117584T2
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- methyl
- pparδ
- inos
- lps
- acid
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Classifications
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/743—Steroid hormones
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
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- A—HUMAN NECESSITIES
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- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
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- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Rheumatology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Endocrinology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Vascular Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0024361.8A GB0024361D0 (en) | 2000-10-05 | 2000-10-05 | Medicaments |
| GB0024361 | 2000-10-05 | ||
| PCT/GB2001/004373 WO2002028434A2 (en) | 2000-10-05 | 2001-10-01 | Use of a ppar delta activator for treating inflammatory conditions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60117584D1 DE60117584D1 (de) | 2006-04-27 |
| DE60117584T2 true DE60117584T2 (de) | 2006-12-21 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60117584T Expired - Fee Related DE60117584T2 (de) | 2000-10-05 | 2001-10-01 | Verwendung von einem ppar-delta aktivator zur behandlung von entzündlichen zuständen |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7084161B2 (https=) |
| EP (1) | EP1324774B1 (https=) |
| JP (1) | JP4106263B2 (https=) |
| AT (1) | ATE318615T1 (https=) |
| AU (1) | AU2001292046A1 (https=) |
| DE (1) | DE60117584T2 (https=) |
| ES (1) | ES2259675T3 (https=) |
| GB (1) | GB0024361D0 (https=) |
| WO (1) | WO2002028434A2 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1357914A2 (en) * | 2001-02-02 | 2003-11-05 | SmithKline Beecham Corporation | Treatment of ppar mediated diseases |
| CA2449247A1 (en) * | 2001-06-11 | 2002-12-19 | Merck & Co., Inc. | A method for treating inflammatory diseases by administering a ppar-delta agonist |
| EP1435946B8 (en) | 2001-09-14 | 2013-12-18 | Amgen Inc. | Linked biaryl compounds |
| FR2836829B1 (fr) * | 2002-03-11 | 2005-11-25 | Bio Merieux | Utilisation de l-alpha-lysophosphatidylcholine pour obtenir la differenciation de monocytes en cellules dendritiques matures in vitro |
| WO2005097098A2 (en) * | 2004-04-01 | 2005-10-20 | Aventis Pharmaceuticals Inc. | Use of ppr delta agonists for treating demyelinating diseases |
| DE602005024384D1 (de) | 2004-05-05 | 2010-12-09 | High Point Pharmaceuticals Llc | Neue verbindungen, ihre herstellung und verwendung |
| US8053598B2 (en) | 2004-05-05 | 2011-11-08 | High Point Pharmaceuticals, Llc | Compounds, their preparation and use |
| WO2006020830A2 (en) | 2004-08-12 | 2006-02-23 | Amgen Inc. | Bisaryl-sulfonamides |
| ES2372617T3 (es) | 2005-06-30 | 2012-01-24 | High Point Pharmaceuticals, Llc | Ácidos fenoxiacéticos como activadores de ppar-delta. |
| CN103224477A (zh) | 2005-12-22 | 2013-07-31 | 高点制药有限责任公司 | 作为PPAR-δ活化剂的苯氧基乙酸 |
| US7943612B2 (en) | 2006-03-09 | 2011-05-17 | High Point Pharmaceuticals, Llc | Compounds that modulate PPAR activity, their preparation and use |
| US20080004281A1 (en) * | 2006-06-28 | 2008-01-03 | Kalypsys, Inc. | Methods for the modulation of crp by the selective modulation of ppar delta |
| US8802705B2 (en) * | 2007-05-21 | 2014-08-12 | Senju Pharmaceutical Co., Ltd. | Pharmaceutical containing PPAR delta agonist |
| AU2010282399A1 (en) * | 2009-08-14 | 2012-03-01 | Cerenis Therapeutics Holding S.A. | Use of PPAR delta ligands for the treatment or prevention of inflammation or energy metabolism/production related diseases |
| KR102038866B1 (ko) * | 2012-12-24 | 2019-10-31 | 서울대학교산학협력단 | ＰＰＡＲδ 활성물질의 항생제, 화상 및 창상 치료제, 당뇨성 족부궤양 치료제로서의 용도 |
| EP3756661A1 (en) | 2013-09-09 | 2020-12-30 | vTv Therapeutics LLC | Use of a ppar-delta agonist for treating muscle atrophy |
| WO2023147309A1 (en) | 2022-01-25 | 2023-08-03 | Reneo Pharmaceuticals, Inc. | Use of ppar-delta agonists in the treatment of disease |
| KR102750722B1 (ko) * | 2022-03-16 | 2025-01-09 | 재단법인 대구경북첨단의료산업진흥재단 | 싸이아다이아졸 화합물 및 이를 포함하는 염증성 질환의 예방 또는 치료용 약학적 조성물 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1856997A (en) | 1996-02-02 | 1997-08-22 | Merck & Co., Inc. | Method for raising hdl cholesterol levels |
| AU8355998A (en) * | 1997-07-24 | 1999-02-16 | Yamanouchi Pharmaceutical Co., Ltd. | Medicinal compositions with cholesterol-lowering effect |
| GB9914977D0 (en) * | 1999-06-25 | 1999-08-25 | Glaxo Group Ltd | Chemical compounds |
-
2000
- 2000-10-05 GB GBGB0024361.8A patent/GB0024361D0/en not_active Ceased
-
2001
- 2001-10-01 US US10/398,629 patent/US7084161B2/en not_active Expired - Fee Related
- 2001-10-01 DE DE60117584T patent/DE60117584T2/de not_active Expired - Fee Related
- 2001-10-01 EP EP01972266A patent/EP1324774B1/en not_active Expired - Lifetime
- 2001-10-01 WO PCT/GB2001/004373 patent/WO2002028434A2/en not_active Ceased
- 2001-10-01 JP JP2002532258A patent/JP4106263B2/ja not_active Expired - Fee Related
- 2001-10-01 AU AU2001292046A patent/AU2001292046A1/en not_active Abandoned
- 2001-10-01 ES ES01972266T patent/ES2259675T3/es not_active Expired - Lifetime
- 2001-10-01 AT AT01972266T patent/ATE318615T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1324774A2 (en) | 2003-07-09 |
| AU2001292046A1 (en) | 2002-04-15 |
| DE60117584D1 (de) | 2006-04-27 |
| US7084161B2 (en) | 2006-08-01 |
| EP1324774B1 (en) | 2006-03-01 |
| ATE318615T1 (de) | 2006-03-15 |
| JP4106263B2 (ja) | 2008-06-25 |
| GB0024361D0 (en) | 2000-11-22 |
| US20050131035A1 (en) | 2005-06-16 |
| ES2259675T3 (es) | 2006-10-16 |
| JP2004510750A (ja) | 2004-04-08 |
| WO2002028434A3 (en) | 2002-08-15 |
| WO2002028434A2 (en) | 2002-04-11 |
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