DE60112159T2 - Nachweis magnetischer Teilchen - Google Patents
Nachweis magnetischer Teilchen Download PDFInfo
- Publication number
- DE60112159T2 DE60112159T2 DE60112159T DE60112159T DE60112159T2 DE 60112159 T2 DE60112159 T2 DE 60112159T2 DE 60112159 T DE60112159 T DE 60112159T DE 60112159 T DE60112159 T DE 60112159T DE 60112159 T2 DE60112159 T2 DE 60112159T2
- Authority
- DE
- Germany
- Prior art keywords
- coil
- sample
- tuned circuit
- circuit
- resonant frequency
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000006249 magnetic particle Substances 0.000 title claims description 34
- 238000001514 detection method Methods 0.000 title description 3
- 238000000034 method Methods 0.000 claims description 46
- 230000005291 magnetic effect Effects 0.000 claims description 28
- 239000000758 substrate Substances 0.000 claims description 25
- 230000008859 change Effects 0.000 claims description 22
- 239000004033 plastic Substances 0.000 claims description 21
- 238000004458 analytical method Methods 0.000 claims description 11
- 238000003018 immunoassay Methods 0.000 claims description 11
- 239000000427 antigen Substances 0.000 claims description 7
- 102000036639 antigens Human genes 0.000 claims description 7
- 108091007433 antigens Proteins 0.000 claims description 7
- 239000002052 molecular layer Substances 0.000 claims description 7
- 230000001419 dependent effect Effects 0.000 claims description 4
- 230000003100 immobilizing effect Effects 0.000 claims description 2
- 208000006930 Pseudomyxoma Peritonei Diseases 0.000 claims 2
- 229920000306 polymethylpentene Polymers 0.000 claims 2
- 235000012771 pancakes Nutrition 0.000 claims 1
- 239000000523 sample Substances 0.000 description 58
- 239000002245 particle Substances 0.000 description 51
- 239000012071 phase Substances 0.000 description 23
- 230000035699 permeability Effects 0.000 description 14
- 230000005298 paramagnetic effect Effects 0.000 description 12
- 238000012360 testing method Methods 0.000 description 11
- 230000000694 effects Effects 0.000 description 10
- 230000004044 response Effects 0.000 description 10
- 230000010355 oscillation Effects 0.000 description 9
- 230000035945 sensitivity Effects 0.000 description 9
- 238000005259 measurement Methods 0.000 description 7
- 239000007853 buffer solution Substances 0.000 description 6
- 229910000859 α-Fe Inorganic materials 0.000 description 6
- 229920003319 Araldite® Polymers 0.000 description 4
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 4
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- 230000008105 immune reaction Effects 0.000 description 2
- 238000012552 review Methods 0.000 description 2
- 239000007790 solid phase Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 101100189378 Caenorhabditis elegans pat-3 gene Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 239000003082 abrasive agent Substances 0.000 description 1
- 238000011953 bioanalysis Methods 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 239000004020 conductor Substances 0.000 description 1
- 239000004035 construction material Substances 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 230000005684 electric field Effects 0.000 description 1
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- 238000005516 engineering process Methods 0.000 description 1
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- 239000011521 glass Substances 0.000 description 1
- 238000009396 hybridization Methods 0.000 description 1
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- 230000001939 inductive effect Effects 0.000 description 1
- 238000012417 linear regression Methods 0.000 description 1
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- 238000002156 mixing Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000000615 nonconductor Substances 0.000 description 1
- 239000002907 paramagnetic material Substances 0.000 description 1
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- 238000009597 pregnancy test Methods 0.000 description 1
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/12—Measuring magnetic properties of articles or specimens of solids or fluids
- G01R33/1223—Measuring permeability, i.e. permeameters
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/804—Radioisotope, e.g. radioimmunoassay
Landscapes
- Physics & Mathematics (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- General Physics & Mathematics (AREA)
- Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
- Measurement Of Resistance Or Impedance (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00302993 | 2000-04-10 | ||
| EP00302993 | 2000-04-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60112159D1 DE60112159D1 (de) | 2005-09-01 |
| DE60112159T2 true DE60112159T2 (de) | 2006-04-27 |
Family
ID=8172903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60112159T Expired - Lifetime DE60112159T2 (de) | 2000-04-10 | 2001-04-09 | Nachweis magnetischer Teilchen |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7241630B2 (enExample) |
| JP (1) | JP2002005892A (enExample) |
| CN (1) | CN1208621C (enExample) |
| AR (1) | AR027785A1 (enExample) |
| AT (1) | ATE300743T1 (enExample) |
| AU (1) | AU770502B2 (enExample) |
| BR (1) | BR0101432A (enExample) |
| CA (1) | CA2342023C (enExample) |
| DE (1) | DE60112159T2 (enExample) |
| MX (1) | MXPA01003640A (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102013109467A1 (de) * | 2013-08-30 | 2015-03-05 | MRB Forschungszentrum für Magnet - Resonanz - Bayern e.V. | Verfahren und Vorrichtung zur Analyse eines magnetische Partikel umfassenden Probenvolumens |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0124341D0 (en) * | 2001-10-10 | 2001-11-28 | Randox Lab Ltd | Assay |
| JP3682459B1 (ja) * | 2004-03-26 | 2005-08-10 | 株式会社ディーゼルユナイテッド | 磁性体濃度計測装置、検出感度向上方法、ゼロ点補償方法及びゼロ点補正方法 |
| JP3682460B1 (ja) * | 2004-04-09 | 2005-08-10 | 株式会社ディーゼルユナイテッド | 運動機関 |
| JP4731927B2 (ja) * | 2005-01-31 | 2011-07-27 | キヤノン株式会社 | 磁性体センサおよび検出キット |
| FI20065257A0 (fi) * | 2006-04-21 | 2006-04-21 | Magnasense Oy | Magneettisten partikkelien mittausjärjestelmä ja menetelmä |
| FI121248B (fi) * | 2006-04-21 | 2010-08-31 | Magnasense Technologies Oy | Laite magneettisten partikkelien mittaamiseksi ja vastaava menetelmä |
| ATE514086T1 (de) * | 2006-05-09 | 2011-07-15 | Koninkl Philips Electronics Nv | Nachweis von zielmolekülen in einer probe unter verwendung eines magnetfelds |
| US8725245B2 (en) * | 2006-08-14 | 2014-05-13 | Kimberly-Clark Worldwide, Inc. | Resonant coil for measuring specimen condition |
| US7755351B2 (en) * | 2007-01-23 | 2010-07-13 | The Boeing Company | Method and apparatus for detecting inconsistencies in fiber reinforced resin parts using eddy currents |
| EP2125215B1 (en) * | 2007-03-21 | 2019-05-08 | University Of The West Of England, Bristol | Particle facilitated testing |
| WO2008144661A1 (en) * | 2007-05-17 | 2008-11-27 | Alcotek Inc. | Systems and methods for determining the position of an electrical solenoid |
| SE532617C2 (sv) * | 2007-11-13 | 2010-03-02 | Lifeassays Ab Publ | Spolmekanism för magnetisk detektor |
| EP2235504A1 (en) * | 2007-12-20 | 2010-10-06 | Koninklijke Philips Electronics N.V. | Positioning of magnetic coils in a sensor device |
| JP2011513755A (ja) * | 2008-03-07 | 2011-04-28 | カリフォルニア インスティテュート オブ テクノロジー | 磁性粒子検出を基本とする実効インダクタンスの変化 |
| CN102246034B (zh) * | 2008-09-15 | 2014-03-12 | 加利福尼亚技术学院 | 具有单珠灵敏度，没有外部磁铁的频移cmos磁力生物传感器阵列 |
| US9599591B2 (en) | 2009-03-06 | 2017-03-21 | California Institute Of Technology | Low cost, portable sensor for molecular assays |
| TWI404340B (zh) * | 2009-11-23 | 2013-08-01 | Mstar Semiconductor Inc | 偏移式鎖相迴路發送器與其相關方法 |
| US9778225B2 (en) | 2010-11-15 | 2017-10-03 | Regents Of The University Of Minnesota | Magnetic search coil for measuring real-time brownian relaxation of magnetic nanoparticles |
| EP2535712A1 (en) | 2011-06-15 | 2012-12-19 | F. Hoffmann-La Roche AG | Analytical system for the preparation of biological material |
| JP6291635B2 (ja) * | 2014-02-10 | 2018-03-14 | 弘美 西村 | 金属材料判別装置 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3858111A (en) * | 1970-11-02 | 1974-12-31 | Singer Co | Method and apparatus for sensing chemical process concentrations |
| US3719882A (en) * | 1970-11-12 | 1973-03-06 | A Pincus | Resonant circuit apparatus for detecting electromagnetic conductive bodies |
| JPS5414242A (en) * | 1977-07-04 | 1979-02-02 | Hitachi Ltd | Measuring method for toner concentration in developer |
| US4314821A (en) * | 1979-04-09 | 1982-02-09 | Minnesota Mining And Manufacturing Company | Sandwich immunoassay using piezoelectric oscillator |
| JPS6390765A (ja) * | 1986-10-03 | 1988-04-21 | Nippon Telegr & Teleph Corp <Ntt> | Ｓｑｕｉｄ免疫測定法 |
| US4912976A (en) * | 1987-06-26 | 1990-04-03 | Beckman Instruments, Inc. | Liquid level sensing apparatus |
| US5679342A (en) * | 1987-11-18 | 1997-10-21 | Chiron Corporation | Hepatitis C virus infected cell systems |
| JPH02133689A (ja) * | 1988-11-14 | 1990-05-22 | Mitsubishi Heavy Ind Ltd | 抄紙機ツインワイヤホーマ |
| DE3900413A1 (de) | 1989-01-09 | 1990-07-12 | N Proizv Ob Abrazivam I Slifov | Vorrichtung zum messen des gehalts magnetischer bestandteile nichtmetallischer proben |
| JP2847788B2 (ja) * | 1989-08-11 | 1999-01-20 | 日本電気株式会社 | セメント混合物中のセメント量の測定装置 |
| JPH03269256A (ja) * | 1990-03-19 | 1991-11-29 | Nec Corp | セメント混合物中のセメント量の測定装置 |
| JPH05172781A (ja) * | 1991-12-26 | 1993-07-09 | Hitachi Metals Ltd | 差動増幅型トナーセンサー |
| JP2981951B2 (ja) * | 1992-06-23 | 1999-11-22 | 株式会社新川 | ワイヤボンデイング装置 |
| JPH0653823A (ja) * | 1992-07-31 | 1994-02-25 | Matsushita Electric Ind Co Ltd | シンセサイザ装置 |
| US5493922A (en) * | 1993-07-09 | 1996-02-27 | Akzo N.V. | Liquid level sensing probe and control circuit |
| US5528142A (en) | 1995-06-19 | 1996-06-18 | Feickert; Carl A. | Resonant eddy analysis- a contactless, inductive method for deriving quantitative information about the conductivity and permeability of a test sample |
| JP3248832B2 (ja) | 1995-08-31 | 2002-01-21 | 三菱電機株式会社 | センサ回路 |
| JP3749959B2 (ja) * | 1996-02-26 | 2006-03-01 | 株式会社シノテスト | 磁性粒子を用いる被検物質の測定方法及び該方法に使用する測定器具 |
| JPH1062390A (ja) * | 1996-08-23 | 1998-03-06 | Konica Corp | 画像形成装置のトナー濃度検出装置 |
| US5922537A (en) | 1996-11-08 | 1999-07-13 | N.o slashed.AB Immunoassay, Inc. | Nanoparticles biosensor |
| US5981297A (en) * | 1997-02-05 | 1999-11-09 | The United States Of America As Represented By The Secretary Of The Navy | Biosensor using magnetically-detected label |
| US5978694A (en) | 1997-02-27 | 1999-11-02 | Uri Rapoport | Method and apparatus for detecting a magnetically responsive substance |
| US6046585A (en) * | 1997-11-21 | 2000-04-04 | Quantum Design, Inc. | Method and apparatus for making quantitative measurements of localized accumulations of target particles having magnetic particles bound thereto |
| EP0947374A3 (en) * | 1998-03-30 | 2001-08-29 | Aisin Seiki Kabushiki Kaisha | Current supply controller for an electric motor |
| DE19929178C2 (de) * | 1999-06-25 | 2002-10-24 | Infineon Technologies Ag | Phasenregelkreissystem |
-
2001
- 2001-03-26 US US09/816,225 patent/US7241630B2/en not_active Expired - Fee Related
- 2001-03-26 CA CA002342023A patent/CA2342023C/en not_active Expired - Fee Related
- 2001-03-28 AU AU31365/01A patent/AU770502B2/en not_active Ceased
- 2001-04-09 AR ARP010101676A patent/AR027785A1/es active IP Right Grant
- 2001-04-09 AT AT01303319T patent/ATE300743T1/de not_active IP Right Cessation
- 2001-04-09 DE DE60112159T patent/DE60112159T2/de not_active Expired - Lifetime
- 2001-04-09 MX MXPA01003640A patent/MXPA01003640A/es unknown
- 2001-04-10 CN CN01116362.3A patent/CN1208621C/zh not_active Expired - Fee Related
- 2001-04-10 BR BR0101432-3A patent/BR0101432A/pt not_active IP Right Cessation
- 2001-04-10 JP JP2001111643A patent/JP2002005892A/ja active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102013109467A1 (de) * | 2013-08-30 | 2015-03-05 | MRB Forschungszentrum für Magnet - Resonanz - Bayern e.V. | Verfahren und Vorrichtung zur Analyse eines magnetische Partikel umfassenden Probenvolumens |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2342023C (en) | 2007-07-03 |
| JP2002005892A (ja) | 2002-01-09 |
| AU3136501A (en) | 2001-10-11 |
| AU770502B2 (en) | 2004-02-26 |
| AR027785A1 (es) | 2003-04-09 |
| MXPA01003640A (es) | 2005-06-30 |
| US7241630B2 (en) | 2007-07-10 |
| CA2342023A1 (en) | 2001-10-10 |
| ATE300743T1 (de) | 2005-08-15 |
| CN1208621C (zh) | 2005-06-29 |
| US20010050555A1 (en) | 2001-12-13 |
| BR0101432A (pt) | 2001-12-26 |
| CN1317693A (zh) | 2001-10-17 |
| DE60112159D1 (de) | 2005-09-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8380 | Miscellaneous part iii |
Free format text: DINGLICHES RECHT WURDE BESTELLT |
|
| 8380 | Miscellaneous part iii |
Free format text: DINGLICHES RECHT WURDE BESTELLT |