DE60104448D1 - "neue 2,3-benzodiazepinderivate und pharmazeutische zusammensetzungen, die diese verbindungen als wirkstoff enthalten" - Google Patents

"neue 2,3-benzodiazepinderivate und pharmazeutische zusammensetzungen, die diese verbindungen als wirkstoff enthalten"

Info

Publication number
DE60104448D1
DE60104448D1 DE60104448T DE60104448T DE60104448D1 DE 60104448 D1 DE60104448 D1 DE 60104448D1 DE 60104448 T DE60104448 T DE 60104448T DE 60104448 T DE60104448 T DE 60104448T DE 60104448 D1 DE60104448 D1 DE 60104448D1
Authority
DE
Germany
Prior art keywords
sup
sub
group
pharmaceutical compositions
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60104448T
Other languages
English (en)
Other versions
DE60104448T2 (de
Inventor
Istvan Ling
Jozsef Barkoczy
Gyula Simig
Zoltan Greff
Zoltan Ratkai
Geza Szabo
Miklos Vegh
Gabor Gigler
Gabor Szenasi
Marko Bernadett Martonne
Gyoergy Levay
Gabor Harsing
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar, Egis Pharmaceuticals PLC filed Critical Egyt Gyogyszervegyeszeti Gyar
Application granted granted Critical
Publication of DE60104448D1 publication Critical patent/DE60104448D1/de
Publication of DE60104448T2 publication Critical patent/DE60104448T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/02—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Addiction (AREA)
  • Urology & Nephrology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE60104448T 2000-12-21 2001-12-19 "neue 2,3-benzodiazepinderivate und pharmazeutische zusammensetzungen, die diese verbindungen als wirkstoff enthalten" Expired - Lifetime DE60104448T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HU0004994A HU225100B1 (hu) 2000-12-21 2000-12-21 2,3-Benzodiazepinszármazékok, ilyen hatóanyagot tartalmazó gyógyászati készítmények és alkalmazásuk
HU0004994 2000-12-21
PCT/HU2001/000151 WO2002050044A1 (en) 2000-12-21 2001-12-19 Novel 2,3-benzodiazepine derivatives and pharmaceutical compositions containing the same as the active ingredient

Publications (2)

Publication Number Publication Date
DE60104448D1 true DE60104448D1 (de) 2004-08-26
DE60104448T2 DE60104448T2 (de) 2005-07-28

Family

ID=89978876

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60104448T Expired - Lifetime DE60104448T2 (de) 2000-12-21 2001-12-19 "neue 2,3-benzodiazepinderivate und pharmazeutische zusammensetzungen, die diese verbindungen als wirkstoff enthalten"

Country Status (20)

Country Link
US (1) US7189711B2 (de)
EP (1) EP1351942B1 (de)
JP (1) JP4201252B2 (de)
AT (1) ATE271548T1 (de)
AU (1) AU2002217356A1 (de)
BG (1) BG66199B1 (de)
CA (1) CA2431761C (de)
CZ (1) CZ301371B6 (de)
DE (1) DE60104448T2 (de)
DK (1) DK1351942T3 (de)
EA (1) EA005867B1 (de)
ES (1) ES2225412T3 (de)
HU (1) HU225100B1 (de)
PL (1) PL211495B1 (de)
PT (1) PT1351942E (de)
RO (1) RO121268B1 (de)
SK (1) SK286620B6 (de)
TR (1) TR200402493T4 (de)
UA (1) UA74615C2 (de)
WO (1) WO2002050044A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0302449A3 (en) * 2003-08-04 2005-06-28 Egis Gyogyszergyar Nyilvanosan 8-chloro-2,3-benzodiazepine derivatives, pharmaceutical compositions containing them and process for producing them
EP1979308A1 (de) * 2005-12-30 2008-10-15 EGIS Gyógyszergyár Nyrt Optische isomere von dihydro-2,3-benzodiazepinen und ihre stereoselektive synthese
CA2881996A1 (en) * 2012-08-16 2014-02-20 Bayer Pharma Aktiengesellschaft 2,3-benzodiazepines
CN105492436A (zh) * 2013-06-17 2016-04-13 拜耳制药股份公司 取代的苯基-2,3-苯并二氮杂环庚三烯

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU191698B (en) * 1984-07-27 1987-03-30 Gyogyszerkutato Intezet Process for producing new 1-aryl-5h-2beta-benzodiazepines
HU219778B (hu) * 1990-12-21 2001-07-30 Gyógyszerkutató Intézet Közös Vállalat Eljárás N-acil-2,3-benzodiazepin-származékok, savaddíciós sóik és az ezeket tartalmazó gyógyászati készítmények előállítására, valamint a vegyületek egy csoportja, és az ezeket tartalmazó gyógyászati készítmények
DE19604920A1 (de) * 1996-02-01 1997-08-07 Schering Ag Neue 2,3-Benzodiazepinderivate, deren Herstellung und Verwendung als Arzneimittel
US5891871A (en) * 1996-03-21 1999-04-06 Cocensys, Inc. Substituted 2,3-benzodiazepin-4-ones and the use thereof
HU9600871D0 (en) * 1996-04-04 1996-05-28 Gyogyszerkutato Intezet New 2,3-benzodiazepine derivatives
HU227128B1 (en) * 1999-07-07 2010-07-28 Egyt Gyogyszervegyeszeti Gyar New 2,3-benzodiazepine derivatives
RU2325811C2 (ru) 2006-06-28 2008-06-10 Общество С Ограниченной Ответственностью "Фито-Маг" Способ хранения плодоовощной и растениеводческой продукции

Also Published As

Publication number Publication date
SK286620B6 (sk) 2009-02-05
EA005867B1 (ru) 2005-06-30
HUP0004994A2 (hu) 2002-11-28
ATE271548T1 (de) 2004-08-15
TR200402493T4 (tr) 2004-12-21
WO2002050044A1 (en) 2002-06-27
HU225100B1 (hu) 2006-06-28
EP1351942B1 (de) 2004-07-21
DE60104448T2 (de) 2005-07-28
BG107932A (bg) 2004-02-27
HU0004994D0 (en) 2001-03-28
CA2431761C (en) 2010-05-25
EP1351942A1 (de) 2003-10-15
PT1351942E (pt) 2004-11-30
ES2225412T3 (es) 2005-03-16
EA200300691A1 (ru) 2003-12-25
CA2431761A1 (en) 2002-06-27
PL211495B1 (pl) 2012-05-31
AU2002217356A1 (en) 2002-07-01
JP2004516284A (ja) 2004-06-03
CZ20031680A3 (cs) 2003-11-12
BG66199B1 (bg) 2012-01-31
CZ301371B6 (cs) 2010-02-03
US20040092510A1 (en) 2004-05-13
PL362029A1 (en) 2004-10-18
RO121268B1 (ro) 2007-02-28
DK1351942T3 (da) 2004-11-22
UA74615C2 (en) 2006-01-16
JP4201252B2 (ja) 2008-12-24
SK7882003A3 (en) 2003-11-04
US7189711B2 (en) 2007-03-13

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