DE60104340D1 - Verfahren zur Herstellung von wirkstofbeladenen Polymer-Micellen Zusammensetzung - Google Patents

Verfahren zur Herstellung von wirkstofbeladenen Polymer-Micellen Zusammensetzung

Info

Publication number
DE60104340D1
DE60104340D1 DE60104340T DE60104340T DE60104340D1 DE 60104340 D1 DE60104340 D1 DE 60104340D1 DE 60104340 T DE60104340 T DE 60104340T DE 60104340 T DE60104340 T DE 60104340T DE 60104340 D1 DE60104340 D1 DE 60104340D1
Authority
DE
Germany
Prior art keywords
drug
polymeric micelle
preparation
production process
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60104340T
Other languages
English (en)
Other versions
DE60104340T2 (de
Inventor
Masayuki Yokoyama
Eiichi Honzawa
Yasuaki Ogawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NanoCarrier Co Ltd
Original Assignee
NanoCarrier Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NanoCarrier Co Ltd filed Critical NanoCarrier Co Ltd
Application granted granted Critical
Publication of DE60104340D1 publication Critical patent/DE60104340D1/de
Publication of DE60104340T2 publication Critical patent/DE60104340T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60104340T 2000-02-09 2001-02-07 Verfahren zur Herstellung von wirkstoffbeladenen Polymer-Mizellen-Zusammen- setzung Expired - Lifetime DE60104340T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000032156A JP3523821B2 (ja) 2000-02-09 2000-02-09 薬物が封入されたポリマーミセルの製造方法および該ポリマーミセル組成物
JP2000032156 2000-02-09

Publications (2)

Publication Number Publication Date
DE60104340D1 true DE60104340D1 (de) 2004-08-26
DE60104340T2 DE60104340T2 (de) 2004-12-02

Family

ID=18556810

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60104340T Expired - Lifetime DE60104340T2 (de) 2000-02-09 2001-02-07 Verfahren zur Herstellung von wirkstoffbeladenen Polymer-Mizellen-Zusammen- setzung

Country Status (9)

Country Link
US (2) US20010014354A1 (de)
EP (1) EP1127570B1 (de)
JP (1) JP3523821B2 (de)
KR (1) KR100797429B1 (de)
CN (1) CN1188112C (de)
AT (1) ATE271380T1 (de)
CA (1) CA2334615C (de)
DE (1) DE60104340T2 (de)
TW (1) TWI235069B (de)

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WO2004105799A1 (ja) * 2003-05-29 2004-12-09 Toudai Tlo, Ltd. 安定化高分子ミセル
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WO2005030257A2 (en) * 2003-09-30 2005-04-07 Solubest Ltd. Water soluble nanoparticles inclusion complexes
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CN100434120C (zh) * 2006-09-14 2008-11-19 同济大学 两亲性荧光靶向纳米胶束及其制备方法
MX2009003092A (es) * 2006-09-22 2009-05-08 Labopharm Inc Composiciones y metodos para suministro de farmaco dirigido a ph.
CA2664852A1 (en) * 2006-10-03 2008-04-10 Nippon Kayaku Kabushiki Kaisha High-molecular weight conjugate of resorcinol derivatives
DK2077293T3 (da) * 2006-10-19 2011-08-15 Nanocarrier Co Ltd Blokcopolymer til lægemiddelkonjugater samt disses farmaceutiske sammensætninger
WO2008056596A1 (en) 2006-11-06 2008-05-15 Nippon Kayaku Kabushiki Kaisha Polymeric derivative of nucleic acid metabolic antagonist
EP2090607B1 (de) 2006-11-08 2015-05-20 Nippon Kayaku Kabushiki Kaisha Polymerderivat eines nukleinsäuremetabolismus-antagonisten
US20080299177A1 (en) * 2007-06-06 2008-12-04 Biovaluation & Analysis, Inc. Supramolecular Complexes for Use in Acoustically Mediated Intracellular Drug Delivery in vivo
EP2206502B1 (de) 2007-09-28 2018-09-12 Nippon Kayaku Kabushiki Kaisha Polymer-konjugat eines steroids
EP2258397B1 (de) 2008-03-18 2017-10-11 Nippon Kayaku Kabushiki Kaisha Polymerkonjugat aus einem physiologisch aktiven stoff
EP2284209B1 (de) 2008-05-08 2016-08-31 Nippon Kayaku Kabushiki Kaisha Polymerkonjugat aus folsäure oder einem folsäurederivat
ES2396134T3 (es) * 2008-05-23 2013-02-19 Nanocarrier Co., Ltd. Derivado polimérico de docetaxel, método de preparación del mismo y sus usos
JP2011162569A (ja) 2008-05-23 2011-08-25 Nano Career Kk カンプトテシン高分子誘導体及びその用途
KR101113044B1 (ko) * 2008-08-29 2012-02-27 동국제약 주식회사 용매교류증발법에 의한 서방출성 미립구의 제조방법
JP5814793B2 (ja) * 2008-11-25 2015-11-17 エコール ポリテクニク フェデラル ド ローザンヌ（エーペーエフエル） ブロックコポリマーおよびその使用
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EP2201935B1 (de) * 2008-12-26 2020-07-08 Samyang Biopharmaceuticals Corporation Polymere Mizellenzusammensetzung, die ein schlecht lösliches Arzneimittel enthält, und zugehöriges Herstellungsverfahren
US20100203150A1 (en) * 2009-02-06 2010-08-12 National Tsing Hua University Novel amphiphilic copolymers and fabrication method thereof
WO2010131675A1 (ja) 2009-05-15 2010-11-18 日本化薬株式会社 水酸基を有する生理活性物質の高分子結合体
JP5031001B2 (ja) * 2009-07-02 2012-09-19 学校法人 関西大学 ナノスフェアの製造方法、ナノスフェア、これを含有する皮膚外用組成物および化粧料
KR101782791B1 (ko) 2010-09-02 2017-09-28 니폰 가야꾸 가부시끼가이샤 약물-블록 코폴리머 복합체와 그것을 함유하는 의약의 제조방법
CA2816997A1 (en) 2010-11-17 2012-05-24 Nippon Kayaku Kabushiki Kaisha Novel polymer derivative of cytidine metabolic antagonist
GB201111439D0 (en) * 2011-07-04 2011-08-17 Syngenta Ltd Formulation
KR101849142B1 (ko) 2011-09-11 2018-04-16 니폰 가야꾸 가부시끼가이샤 블록 공중합체의 제조방법
US9949928B2 (en) * 2013-05-01 2018-04-24 The Regents Of The University Of Colorado, A Body Corporate Biodegradable copolymers, systems including the copolymers, and methods of forming and using same
CN104415008A (zh) * 2013-08-30 2015-03-18 成都市绿科华通科技有限公司 抗癌高分子药物微胶囊的制备方法
CN104856949A (zh) * 2014-02-25 2015-08-26 苏州雷纳药物研发有限公司 一种多西他赛胶束载药系统及其制备方法
CN104072706A (zh) * 2014-07-08 2014-10-01 成都市绿科华通科技有限公司 多功能聚乳酸衍生物药物载体材料
CN104086722A (zh) * 2014-07-08 2014-10-08 成都市绿科华通科技有限公司 一种生物多孔材料的制备方法
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Also Published As

Publication number Publication date
JP2001226294A (ja) 2001-08-21
DE60104340T2 (de) 2004-12-02
KR20010078773A (ko) 2001-08-21
JP3523821B2 (ja) 2004-04-26
CA2334615C (en) 2010-09-07
CN1188112C (zh) 2005-02-09
US7223419B2 (en) 2007-05-29
EP1127570A3 (de) 2001-09-12
EP1127570B1 (de) 2004-07-21
US20040056372A1 (en) 2004-03-25
KR100797429B1 (ko) 2008-01-23
CA2334615A1 (en) 2001-08-09
ATE271380T1 (de) 2004-08-15
US20010014354A1 (en) 2001-08-16
CN1307866A (zh) 2001-08-15
TWI235069B (en) 2005-07-01
EP1127570A2 (de) 2001-08-29

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