DE60027890T2 - Streptococcus pneumoniae proteine und impfstoffe - Google Patents

Streptococcus pneumoniae proteine und impfstoffe Download PDF

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Publication number
DE60027890T2
DE60027890T2 DE60027890T DE60027890T DE60027890T2 DE 60027890 T2 DE60027890 T2 DE 60027890T2 DE 60027890 T DE60027890 T DE 60027890T DE 60027890 T DE60027890 T DE 60027890T DE 60027890 T2 DE60027890 T2 DE 60027890T2
Authority
DE
Germany
Prior art keywords
polypeptide
polypeptides
vaccine
amino acid
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60027890T
Other languages
German (de)
English (en)
Other versions
DE60027890D1 (de
Inventor
E. John Germantown ADAMOU
H. Gil Rockville CHOI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
MedImmune LLC
Original Assignee
Human Genome Sciences Inc
MedImmune LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences Inc, MedImmune LLC filed Critical Human Genome Sciences Inc
Publication of DE60027890D1 publication Critical patent/DE60027890D1/de
Application granted granted Critical
Publication of DE60027890T2 publication Critical patent/DE60027890T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1275Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Streptococcus (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60027890T 1999-06-10 2000-06-09 Streptococcus pneumoniae proteine und impfstoffe Expired - Lifetime DE60027890T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13845399P 1999-06-10 1999-06-10
US138453P 1999-06-10
PCT/US2000/015925 WO2000076540A2 (en) 1999-06-10 2000-06-09 Streptococcus pneumoniae proteins and vaccines

Publications (2)

Publication Number Publication Date
DE60027890D1 DE60027890D1 (de) 2006-06-14
DE60027890T2 true DE60027890T2 (de) 2007-04-19

Family

ID=22482080

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60027890T Expired - Lifetime DE60027890T2 (de) 1999-06-10 2000-06-09 Streptococcus pneumoniae proteine und impfstoffe
DE60045721T Expired - Lifetime DE60045721D1 (de) 1999-06-10 2000-06-09 Streptococcus pneumoniae Proteine und Impfstoffe

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE60045721T Expired - Lifetime DE60045721D1 (de) 1999-06-10 2000-06-09 Streptococcus pneumoniae Proteine und Impfstoffe

Country Status (9)

Country Link
EP (2) EP1185297B1 (enExample)
JP (1) JP2003501110A (enExample)
AT (2) ATE325620T1 (enExample)
AU (1) AU777856B2 (enExample)
CA (1) CA2371714C (enExample)
DE (2) DE60027890T2 (enExample)
ES (2) ES2264419T3 (enExample)
HK (1) HK1043943A1 (enExample)
WO (1) WO2000076540A2 (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7135560B1 (en) 1997-07-02 2006-11-14 Sanofi Pasteur Limited Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics
US6800744B1 (en) 1997-07-02 2004-10-05 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics
US7128918B1 (en) 1998-12-23 2006-10-31 Id Biomedical Corporation Streptococcus antigens
US7074415B2 (en) 2000-06-20 2006-07-11 Id Biomedical Corporation Streptococcus antigens
GB0022742D0 (en) 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
AU2002351623A1 (en) 2001-12-20 2003-07-09 Shire Biochem Inc. Streptococcus antigens
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
PL3017827T3 (pl) 2005-12-22 2019-04-30 Glaxosmithkline Biologicals Sa Szczepionka z koniugatem polisacharydu pneumokokowego
GB0607088D0 (en) 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
US9610339B2 (en) 2007-06-26 2017-04-04 Glaxosmithkline Biologicals, S.A. Vaccine comprising Streptococcus pneumoniae capsular polysaccharide conjugates
GB0714963D0 (en) 2007-08-01 2007-09-12 Novartis Ag Compositions comprising antigens
NZ586367A (en) 2007-12-13 2012-04-27 Intervacc Ab Improved immunizing composition comprising an antigen from Streptococcus equi
PL2268618T3 (pl) 2008-03-03 2015-11-30 Novartis Ag Związki i kompozycje jako modulatory aktywności receptorów TLR
PL2271360T3 (pl) 2008-04-16 2016-03-31 Glaxosmithkline Biologicals Sa Szczepionka
CN102762226A (zh) 2009-06-10 2012-10-31 诺华有限公司 含苯并萘啶的疫苗
MX2012000158A (es) 2009-06-29 2012-06-08 Genocea Biosciences Inc Vacunas y composiciones contra streptococcus pneumoniae.
JO3257B1 (ar) 2009-09-02 2018-09-16 Novartis Ag مركبات وتركيبات كمعدلات لفاعلية tlr
ES2443952T3 (es) 2009-09-02 2014-02-21 Novartis Ag Composiciones inmunógenas que incluyen moduladores de la actividad de TLR
US20120237536A1 (en) 2009-09-10 2012-09-20 Novartis Combination vaccines against respiratory tract diseases
WO2011057148A1 (en) 2009-11-05 2011-05-12 Irm Llc Compounds and compositions as tlr-7 activity modulators
US9408907B2 (en) 2009-12-15 2016-08-09 Glaxosmithkline Biologicals Sa Homogenous suspension of immunopotentiating compounds and uses thereof
GB201003924D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Immunogenic composition
JP5848748B2 (ja) 2010-03-23 2016-01-27 アイアールエム・リミテッド・ライアビリティ・カンパニーIrm,Llc 感染症、炎症、呼吸器疾患などの処置に使用するtlr2アゴニストとしての化合物(システインベースのリポペプチド)および組成物
WO2012072769A1 (en) 2010-12-01 2012-06-07 Novartis Ag Pneumococcal rrgb epitopes and clade combinations
CN105833260A (zh) 2011-01-20 2016-08-10 健诺西生物科学公司 针对肺炎链球菌(Streptococcus Pneumoniae)的疫苗和组合物
BR112013029514A2 (pt) 2011-05-17 2019-09-24 Glaxosmithkline Biologicals Sa composição imunogênica, vacina, e, método de tratar ou impedir uma doença
JP2015510872A (ja) 2012-03-07 2015-04-13 ノバルティス アーゲー Streptococcuspneumoniae抗原の増強された製剤
TR201807340T4 (tr) 2013-02-01 2018-06-21 Glaxosmithkline Biologicals Sa Çan benzeri reseptör agonistleri içeren immünolojik kompozisyonların intradermal yoldan verilmesi.
IL276608B2 (en) 2018-02-12 2024-04-01 Inimmune Corp Toll-like receptor ligands
JP2023547676A (ja) 2020-11-04 2023-11-13 エリゴ・バイオサイエンス DNAペイロードをアクネ菌集団へとin situ送達するためのファージ由来粒子

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998018931A2 (en) * 1996-10-31 1998-05-07 Human Genome Sciences, Inc. Streptococcus pneumoniae polynucleotides and sequences
EP1144640A3 (en) * 1998-07-27 2001-11-28 Microbial Technics Limited Nucleic acids and proteins from streptococcus pneumoniae

Also Published As

Publication number Publication date
DE60045721D1 (de) 2011-04-21
WO2000076540A3 (en) 2001-02-08
HK1043943A1 (zh) 2002-10-04
EP1731166A3 (en) 2007-02-21
DE60027890D1 (de) 2006-06-14
ES2264419T3 (es) 2007-01-01
EP1731166A2 (en) 2006-12-13
CA2371714C (en) 2012-12-04
EP1185297B1 (en) 2006-05-10
JP2003501110A (ja) 2003-01-14
EP1731166B1 (en) 2011-03-09
EP1185297A2 (en) 2002-03-13
WO2000076540A2 (en) 2000-12-21
ES2360296T3 (es) 2011-06-02
CA2371714A1 (en) 2000-12-21
ATE500843T1 (de) 2011-03-15
AU5477800A (en) 2001-01-02
AU777856B2 (en) 2004-11-04
ATE325620T1 (de) 2006-06-15

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