DE60024787T3 - Antikörper zum selektiven Nachweis von Prion PrP Sc Isoformen - Google Patents
Antikörper zum selektiven Nachweis von Prion PrP Sc Isoformen Download PDFInfo
- Publication number
- DE60024787T3 DE60024787T3 DE60024787T DE60024787T DE60024787T3 DE 60024787 T3 DE60024787 T3 DE 60024787T3 DE 60024787 T DE60024787 T DE 60024787T DE 60024787 T DE60024787 T DE 60024787T DE 60024787 T3 DE60024787 T3 DE 60024787T3
- Authority
- DE
- Germany
- Prior art keywords
- tyr
- gln
- glu
- prp
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Psychiatry (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE60024787T DE60024787T3 (de) | 2000-05-23 | 2000-05-23 | Antikörper zum selektiven Nachweis von Prion PrP Sc Isoformen |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00111108A EP1158003B2 (en) | 2000-05-23 | 2000-05-23 | Antibodies capable to selectively detect prion PrP Sc isoforms |
| DE60024787T DE60024787T3 (de) | 2000-05-23 | 2000-05-23 | Antikörper zum selektiven Nachweis von Prion PrP Sc Isoformen |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DE60024787D1 DE60024787D1 (de) | 2006-01-19 |
| DE60024787T2 DE60024787T2 (de) | 2006-09-07 |
| DE60024787T3 true DE60024787T3 (de) | 2013-06-06 |
Family
ID=8168816
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60024787T Expired - Lifetime DE60024787T3 (de) | 2000-05-23 | 2000-05-23 | Antikörper zum selektiven Nachweis von Prion PrP Sc Isoformen |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP1158003B2 (https=) |
| JP (1) | JP5042430B2 (https=) |
| KR (1) | KR100829447B1 (https=) |
| CN (1) | CN1250572C (https=) |
| AR (1) | AR029098A1 (https=) |
| AT (1) | ATE312848T1 (https=) |
| AU (2) | AU2001284355B2 (https=) |
| CA (1) | CA2407905C (https=) |
| DE (1) | DE60024787T3 (https=) |
| DK (1) | DK1158003T4 (https=) |
| ES (1) | ES2253156T5 (https=) |
| HU (1) | HU229454B1 (https=) |
| PL (1) | PL208292B1 (https=) |
| WO (1) | WO2001090191A2 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003059386A2 (en) * | 2002-01-18 | 2003-07-24 | Cytos Biotechnology Ag | Prion protein carrier-conjugates |
| EP1596199A1 (en) * | 2004-05-14 | 2005-11-16 | Prionics AG | Method for the detection of disease-related prion |
| JP4246777B1 (ja) * | 2007-11-20 | 2009-04-02 | 森永乳業株式会社 | 異常型プリオン蛋白質結合剤および異常型プリオン蛋白質の検出方法 |
| EP2135880A1 (en) * | 2008-06-17 | 2009-12-23 | Heinrich-Heine-Universität Düsseldorf | Anti-prion protein antibody fragment |
| AU2009301580B2 (en) | 2008-10-06 | 2015-11-26 | The University Of British Columbia | Methods and systems for predicting misfolded protein epitopes |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ246059A (en) * | 1991-12-03 | 1995-08-28 | Proteus Molecular Design | Synthetic polypeptides with at least one antigenic site of a prion protein, methods of their use and manufacture, antibodies thereto, compositions and kits |
| DE852011T1 (de) * | 1995-09-14 | 2001-10-11 | Scripps Res Inst La Jolla | Für natives prp-sc spezifische antikörper |
| EP0861900A1 (en) † | 1997-02-21 | 1998-09-02 | Erziehungsdirektion Of The Canton Zurich | Immunological detection of prions |
| DE19741607A1 (de) * | 1997-09-20 | 1999-03-25 | Prionics Ag | Synthetische Polypeptide zur Diagnose und Therapie von Prionerkrankungen |
-
2000
- 2000-05-23 EP EP00111108A patent/EP1158003B2/en not_active Expired - Lifetime
- 2000-05-23 ES ES00111108T patent/ES2253156T5/es not_active Expired - Lifetime
- 2000-05-23 DE DE60024787T patent/DE60024787T3/de not_active Expired - Lifetime
- 2000-05-23 DK DK00111108.7T patent/DK1158003T4/da active
- 2000-05-23 AT AT00111108T patent/ATE312848T1/de active
-
2001
- 2001-05-15 PL PL360139A patent/PL208292B1/pl unknown
- 2001-05-15 CA CA2407905A patent/CA2407905C/en not_active Expired - Fee Related
- 2001-05-15 WO PCT/IB2001/001666 patent/WO2001090191A2/en not_active Ceased
- 2001-05-15 KR KR1020027015692A patent/KR100829447B1/ko not_active Expired - Fee Related
- 2001-05-15 AU AU2001284355A patent/AU2001284355B2/en not_active Ceased
- 2001-05-15 HU HU0302413A patent/HU229454B1/hu not_active IP Right Cessation
- 2001-05-15 AU AU8435501A patent/AU8435501A/xx active Pending
- 2001-05-15 CN CNB01809936XA patent/CN1250572C/zh not_active Expired - Fee Related
- 2001-05-15 JP JP2001587002A patent/JP5042430B2/ja not_active Expired - Fee Related
- 2001-05-23 AR ARP010102453A patent/AR029098A1/es active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| ES2253156T5 (es) | 2013-04-30 |
| CN1441811A (zh) | 2003-09-10 |
| AU8435501A (en) | 2001-12-03 |
| AU2001284355B2 (en) | 2005-11-10 |
| PL208292B1 (pl) | 2011-04-29 |
| EP1158003B2 (en) | 2012-12-26 |
| EP1158003A1 (en) | 2001-11-28 |
| HUP0302413A2 (hu) | 2003-10-28 |
| HU229454B1 (en) | 2013-12-30 |
| WO2001090191A3 (en) | 2002-06-20 |
| ATE312848T1 (de) | 2005-12-15 |
| EP1158003B1 (en) | 2005-12-14 |
| PL360139A1 (en) | 2004-09-06 |
| WO2001090191A2 (en) | 2001-11-29 |
| ES2253156T3 (es) | 2006-06-01 |
| JP2003534000A (ja) | 2003-11-18 |
| DK1158003T4 (da) | 2013-04-08 |
| KR20030014234A (ko) | 2003-02-15 |
| KR100829447B1 (ko) | 2008-05-15 |
| CA2407905A1 (en) | 2001-11-29 |
| DK1158003T3 (da) | 2006-05-01 |
| JP5042430B2 (ja) | 2012-10-03 |
| DE60024787T2 (de) | 2006-09-07 |
| CN1250572C (zh) | 2006-04-12 |
| CA2407905C (en) | 2012-08-14 |
| AR029098A1 (es) | 2003-06-04 |
| DE60024787D1 (de) | 2006-01-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8363 | Opposition against the patent | ||
| R102 | Epo decision maintaining patent in amended form now final |
Ref document number: 1158003 Country of ref document: EP Effective date: 20121226 |