JP5042430B2 - プリオンＰｒＰＳｃイソ型を選択的に検出し得る抗体 - Google Patents

プリオンＰｒＰＳｃイソ型を選択的に検出し得る抗体 Download PDF

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Publication number
JP5042430B2
JP5042430B2 JP2001587002A JP2001587002A JP5042430B2 JP 5042430 B2 JP5042430 B2 JP 5042430B2 JP 2001587002 A JP2001587002 A JP 2001587002A JP 2001587002 A JP2001587002 A JP 2001587002A JP 5042430 B2 JP5042430 B2 JP 5042430B2
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JP
Japan
Prior art keywords
antibody
prp
bse
antibodies
peptide
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Expired - Fee Related
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JP2001587002A
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English (en)
Japanese (ja)
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JP2003534000A5 (https=
JP2003534000A (ja
Inventor
クリン−セルベック，ウラードカ
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Blood Transfusion Centre of Slovenia
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Blood Transfusion Centre of Slovenia
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychiatry (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2001587002A 2000-05-23 2001-05-15 プリオンＰｒＰＳｃイソ型を選択的に検出し得る抗体 Expired - Fee Related JP5042430B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00111108.7 2000-05-23
EP00111108A EP1158003B2 (en) 2000-05-23 2000-05-23 Antibodies capable to selectively detect prion PrP Sc isoforms
PCT/IB2001/001666 WO2001090191A2 (en) 2000-05-23 2001-05-15 ANTIBODIES CAPABLE TO SELECTIVELY DETECT PRION PrPSc ISOFORMS

Publications (3)

Publication Number Publication Date
JP2003534000A JP2003534000A (ja) 2003-11-18
JP2003534000A5 JP2003534000A5 (https=) 2008-06-26
JP5042430B2 true JP5042430B2 (ja) 2012-10-03

Family

ID=8168816

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001587002A Expired - Fee Related JP5042430B2 (ja) 2000-05-23 2001-05-15 プリオンＰｒＰＳｃイソ型を選択的に検出し得る抗体

Country Status (14)

Country Link
EP (1) EP1158003B2 (https=)
JP (1) JP5042430B2 (https=)
KR (1) KR100829447B1 (https=)
CN (1) CN1250572C (https=)
AR (1) AR029098A1 (https=)
AT (1) ATE312848T1 (https=)
AU (2) AU2001284355B2 (https=)
CA (1) CA2407905C (https=)
DE (1) DE60024787T3 (https=)
DK (1) DK1158003T4 (https=)
ES (1) ES2253156T5 (https=)
HU (1) HU229454B1 (https=)
PL (1) PL208292B1 (https=)
WO (1) WO2001090191A2 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003059386A2 (en) * 2002-01-18 2003-07-24 Cytos Biotechnology Ag Prion protein carrier-conjugates
EP1596199A1 (en) * 2004-05-14 2005-11-16 Prionics AG Method for the detection of disease-related prion
JP4246777B1 (ja) * 2007-11-20 2009-04-02 森永乳業株式会社 異常型プリオン蛋白質結合剤および異常型プリオン蛋白質の検出方法
EP2135880A1 (en) * 2008-06-17 2009-12-23 Heinrich-Heine-Universität Düsseldorf Anti-prion protein antibody fragment
AU2009301580B2 (en) 2008-10-06 2015-11-26 The University Of British Columbia Methods and systems for predicting misfolded protein epitopes

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ246059A (en) * 1991-12-03 1995-08-28 Proteus Molecular Design Synthetic polypeptides with at least one antigenic site of a prion protein, methods of their use and manufacture, antibodies thereto, compositions and kits
DE852011T1 (de) * 1995-09-14 2001-10-11 Scripps Res Inst La Jolla Für natives prp-sc spezifische antikörper
EP0861900A1 (en) † 1997-02-21 1998-09-02 Erziehungsdirektion Of The Canton Zurich Immunological detection of prions
DE19741607A1 (de) * 1997-09-20 1999-03-25 Prionics Ag Synthetische Polypeptide zur Diagnose und Therapie von Prionerkrankungen

Also Published As

Publication number Publication date
ES2253156T5 (es) 2013-04-30
DE60024787T3 (de) 2013-06-06
CN1441811A (zh) 2003-09-10
AU8435501A (en) 2001-12-03
AU2001284355B2 (en) 2005-11-10
PL208292B1 (pl) 2011-04-29
EP1158003B2 (en) 2012-12-26
EP1158003A1 (en) 2001-11-28
HUP0302413A2 (hu) 2003-10-28
HU229454B1 (en) 2013-12-30
WO2001090191A3 (en) 2002-06-20
ATE312848T1 (de) 2005-12-15
EP1158003B1 (en) 2005-12-14
PL360139A1 (en) 2004-09-06
WO2001090191A2 (en) 2001-11-29
ES2253156T3 (es) 2006-06-01
JP2003534000A (ja) 2003-11-18
DK1158003T4 (da) 2013-04-08
KR20030014234A (ko) 2003-02-15
KR100829447B1 (ko) 2008-05-15
CA2407905A1 (en) 2001-11-29
DK1158003T3 (da) 2006-05-01
DE60024787T2 (de) 2006-09-07
CN1250572C (zh) 2006-04-12
CA2407905C (en) 2012-08-14
AR029098A1 (es) 2003-06-04
DE60024787D1 (de) 2006-01-19

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