KR100829447B1 - 프리온 단백질의 진전병 동형체들을 선택적으로 검출할 수있는 항체 - Google Patents
프리온 단백질의 진전병 동형체들을 선택적으로 검출할 수있는 항체 Download PDFInfo
- Publication number
- KR100829447B1 KR100829447B1 KR1020027015692A KR20027015692A KR100829447B1 KR 100829447 B1 KR100829447 B1 KR 100829447B1 KR 1020027015692 A KR1020027015692 A KR 1020027015692A KR 20027015692 A KR20027015692 A KR 20027015692A KR 100829447 B1 KR100829447 B1 KR 100829447B1
- Authority
- KR
- South Korea
- Prior art keywords
- tyr
- gln
- glu
- antibody
- antibodies
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Psychiatry (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00111108.7 | 2000-05-23 | ||
| EP00111108A EP1158003B2 (en) | 2000-05-23 | 2000-05-23 | Antibodies capable to selectively detect prion PrP Sc isoforms |
| PCT/IB2001/001666 WO2001090191A2 (en) | 2000-05-23 | 2001-05-15 | ANTIBODIES CAPABLE TO SELECTIVELY DETECT PRION PrPSc ISOFORMS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20030014234A KR20030014234A (ko) | 2003-02-15 |
| KR100829447B1 true KR100829447B1 (ko) | 2008-05-15 |
Family
ID=8168816
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020027015692A Expired - Fee Related KR100829447B1 (ko) | 2000-05-23 | 2001-05-15 | 프리온 단백질의 진전병 동형체들을 선택적으로 검출할 수있는 항체 |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP1158003B2 (https=) |
| JP (1) | JP5042430B2 (https=) |
| KR (1) | KR100829447B1 (https=) |
| CN (1) | CN1250572C (https=) |
| AR (1) | AR029098A1 (https=) |
| AT (1) | ATE312848T1 (https=) |
| AU (2) | AU2001284355B2 (https=) |
| CA (1) | CA2407905C (https=) |
| DE (1) | DE60024787T3 (https=) |
| DK (1) | DK1158003T4 (https=) |
| ES (1) | ES2253156T5 (https=) |
| HU (1) | HU229454B1 (https=) |
| PL (1) | PL208292B1 (https=) |
| WO (1) | WO2001090191A2 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003059386A2 (en) * | 2002-01-18 | 2003-07-24 | Cytos Biotechnology Ag | Prion protein carrier-conjugates |
| EP1596199A1 (en) * | 2004-05-14 | 2005-11-16 | Prionics AG | Method for the detection of disease-related prion |
| JP4246777B1 (ja) * | 2007-11-20 | 2009-04-02 | 森永乳業株式会社 | 異常型プリオン蛋白質結合剤および異常型プリオン蛋白質の検出方法 |
| EP2135880A1 (en) * | 2008-06-17 | 2009-12-23 | Heinrich-Heine-Universität Düsseldorf | Anti-prion protein antibody fragment |
| AU2009301580B2 (en) | 2008-10-06 | 2015-11-26 | The University Of British Columbia | Methods and systems for predicting misfolded protein epitopes |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993011155A1 (en) * | 1991-12-03 | 1993-06-10 | Proteus Molecular Design Limited | Fragments of prion proteins |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE852011T1 (de) * | 1995-09-14 | 2001-10-11 | Scripps Res Inst La Jolla | Für natives prp-sc spezifische antikörper |
| EP0861900A1 (en) † | 1997-02-21 | 1998-09-02 | Erziehungsdirektion Of The Canton Zurich | Immunological detection of prions |
| DE19741607A1 (de) * | 1997-09-20 | 1999-03-25 | Prionics Ag | Synthetische Polypeptide zur Diagnose und Therapie von Prionerkrankungen |
-
2000
- 2000-05-23 EP EP00111108A patent/EP1158003B2/en not_active Expired - Lifetime
- 2000-05-23 ES ES00111108T patent/ES2253156T5/es not_active Expired - Lifetime
- 2000-05-23 DE DE60024787T patent/DE60024787T3/de not_active Expired - Lifetime
- 2000-05-23 DK DK00111108.7T patent/DK1158003T4/da active
- 2000-05-23 AT AT00111108T patent/ATE312848T1/de active
-
2001
- 2001-05-15 PL PL360139A patent/PL208292B1/pl unknown
- 2001-05-15 CA CA2407905A patent/CA2407905C/en not_active Expired - Fee Related
- 2001-05-15 WO PCT/IB2001/001666 patent/WO2001090191A2/en not_active Ceased
- 2001-05-15 KR KR1020027015692A patent/KR100829447B1/ko not_active Expired - Fee Related
- 2001-05-15 AU AU2001284355A patent/AU2001284355B2/en not_active Ceased
- 2001-05-15 HU HU0302413A patent/HU229454B1/hu not_active IP Right Cessation
- 2001-05-15 AU AU8435501A patent/AU8435501A/xx active Pending
- 2001-05-15 CN CNB01809936XA patent/CN1250572C/zh not_active Expired - Fee Related
- 2001-05-15 JP JP2001587002A patent/JP5042430B2/ja not_active Expired - Fee Related
- 2001-05-23 AR ARP010102453A patent/AR029098A1/es active IP Right Grant
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993011155A1 (en) * | 1991-12-03 | 1993-06-10 | Proteus Molecular Design Limited | Fragments of prion proteins |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2253156T5 (es) | 2013-04-30 |
| DE60024787T3 (de) | 2013-06-06 |
| CN1441811A (zh) | 2003-09-10 |
| AU8435501A (en) | 2001-12-03 |
| AU2001284355B2 (en) | 2005-11-10 |
| PL208292B1 (pl) | 2011-04-29 |
| EP1158003B2 (en) | 2012-12-26 |
| EP1158003A1 (en) | 2001-11-28 |
| HUP0302413A2 (hu) | 2003-10-28 |
| HU229454B1 (en) | 2013-12-30 |
| WO2001090191A3 (en) | 2002-06-20 |
| ATE312848T1 (de) | 2005-12-15 |
| EP1158003B1 (en) | 2005-12-14 |
| PL360139A1 (en) | 2004-09-06 |
| WO2001090191A2 (en) | 2001-11-29 |
| ES2253156T3 (es) | 2006-06-01 |
| JP2003534000A (ja) | 2003-11-18 |
| DK1158003T4 (da) | 2013-04-08 |
| KR20030014234A (ko) | 2003-02-15 |
| CA2407905A1 (en) | 2001-11-29 |
| DK1158003T3 (da) | 2006-05-01 |
| JP5042430B2 (ja) | 2012-10-03 |
| DE60024787T2 (de) | 2006-09-07 |
| CN1250572C (zh) | 2006-04-12 |
| CA2407905C (en) | 2012-08-14 |
| AR029098A1 (es) | 2003-06-04 |
| DE60024787D1 (de) | 2006-01-19 |
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