CA2407905C - Antibodies capable to selectively detect prion prpsc isoforms - Google Patents

Antibodies capable to selectively detect prion prpsc isoforms Download PDF

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Publication number
CA2407905C
CA2407905C CA2407905A CA2407905A CA2407905C CA 2407905 C CA2407905 C CA 2407905C CA 2407905 A CA2407905 A CA 2407905A CA 2407905 A CA2407905 A CA 2407905A CA 2407905 C CA2407905 C CA 2407905C
Authority
CA
Canada
Prior art keywords
tyr
gln
glu
antibody
disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2407905A
Other languages
English (en)
French (fr)
Other versions
CA2407905A1 (en
Inventor
Vladka Curin-Serbec
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Blood Transfusion Centre of Slovenia
Original Assignee
Blood Transfusion Centre of Slovenia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8168816&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2407905(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Blood Transfusion Centre of Slovenia filed Critical Blood Transfusion Centre of Slovenia
Publication of CA2407905A1 publication Critical patent/CA2407905A1/en
Application granted granted Critical
Publication of CA2407905C publication Critical patent/CA2407905C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychiatry (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA2407905A 2000-05-23 2001-05-15 Antibodies capable to selectively detect prion prpsc isoforms Expired - Fee Related CA2407905C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00111108.7 2000-05-23
EP00111108A EP1158003B2 (en) 2000-05-23 2000-05-23 Antibodies capable to selectively detect prion PrP Sc isoforms
PCT/IB2001/001666 WO2001090191A2 (en) 2000-05-23 2001-05-15 ANTIBODIES CAPABLE TO SELECTIVELY DETECT PRION PrPSc ISOFORMS

Publications (2)

Publication Number Publication Date
CA2407905A1 CA2407905A1 (en) 2001-11-29
CA2407905C true CA2407905C (en) 2012-08-14

Family

ID=8168816

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2407905A Expired - Fee Related CA2407905C (en) 2000-05-23 2001-05-15 Antibodies capable to selectively detect prion prpsc isoforms

Country Status (14)

Country Link
EP (1) EP1158003B2 (https=)
JP (1) JP5042430B2 (https=)
KR (1) KR100829447B1 (https=)
CN (1) CN1250572C (https=)
AR (1) AR029098A1 (https=)
AT (1) ATE312848T1 (https=)
AU (2) AU2001284355B2 (https=)
CA (1) CA2407905C (https=)
DE (1) DE60024787T3 (https=)
DK (1) DK1158003T4 (https=)
ES (1) ES2253156T5 (https=)
HU (1) HU229454B1 (https=)
PL (1) PL208292B1 (https=)
WO (1) WO2001090191A2 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003059386A2 (en) * 2002-01-18 2003-07-24 Cytos Biotechnology Ag Prion protein carrier-conjugates
EP1596199A1 (en) * 2004-05-14 2005-11-16 Prionics AG Method for the detection of disease-related prion
JP4246777B1 (ja) * 2007-11-20 2009-04-02 森永乳業株式会社 異常型プリオン蛋白質結合剤および異常型プリオン蛋白質の検出方法
EP2135880A1 (en) * 2008-06-17 2009-12-23 Heinrich-Heine-Universität Düsseldorf Anti-prion protein antibody fragment
AU2009301580B2 (en) 2008-10-06 2015-11-26 The University Of British Columbia Methods and systems for predicting misfolded protein epitopes

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ246059A (en) * 1991-12-03 1995-08-28 Proteus Molecular Design Synthetic polypeptides with at least one antigenic site of a prion protein, methods of their use and manufacture, antibodies thereto, compositions and kits
DE852011T1 (de) * 1995-09-14 2001-10-11 Scripps Res Inst La Jolla Für natives prp-sc spezifische antikörper
EP0861900A1 (en) † 1997-02-21 1998-09-02 Erziehungsdirektion Of The Canton Zurich Immunological detection of prions
DE19741607A1 (de) * 1997-09-20 1999-03-25 Prionics Ag Synthetische Polypeptide zur Diagnose und Therapie von Prionerkrankungen

Also Published As

Publication number Publication date
ES2253156T5 (es) 2013-04-30
DE60024787T3 (de) 2013-06-06
CN1441811A (zh) 2003-09-10
AU8435501A (en) 2001-12-03
AU2001284355B2 (en) 2005-11-10
PL208292B1 (pl) 2011-04-29
EP1158003B2 (en) 2012-12-26
EP1158003A1 (en) 2001-11-28
HUP0302413A2 (hu) 2003-10-28
HU229454B1 (en) 2013-12-30
WO2001090191A3 (en) 2002-06-20
ATE312848T1 (de) 2005-12-15
EP1158003B1 (en) 2005-12-14
PL360139A1 (en) 2004-09-06
WO2001090191A2 (en) 2001-11-29
ES2253156T3 (es) 2006-06-01
JP2003534000A (ja) 2003-11-18
DK1158003T4 (da) 2013-04-08
KR20030014234A (ko) 2003-02-15
KR100829447B1 (ko) 2008-05-15
CA2407905A1 (en) 2001-11-29
DK1158003T3 (da) 2006-05-01
JP5042430B2 (ja) 2012-10-03
DE60024787T2 (de) 2006-09-07
CN1250572C (zh) 2006-04-12
AR029098A1 (es) 2003-06-04
DE60024787D1 (de) 2006-01-19

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20170515