DE60024669T2 - Hämatologische bestimmung und reagenz - Google Patents

Hämatologische bestimmung und reagenz Download PDF

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Publication number
DE60024669T2
DE60024669T2 DE60024669T DE60024669T DE60024669T2 DE 60024669 T2 DE60024669 T2 DE 60024669T2 DE 60024669 T DE60024669 T DE 60024669T DE 60024669 T DE60024669 T DE 60024669T DE 60024669 T2 DE60024669 T2 DE 60024669T2
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DE
Germany
Prior art keywords
factor
coagulation
sample
test according
reagent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60024669T
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German (de)
English (en)
Other versions
DE60024669D1 (de
Inventor
Maria Patrizia GEMPELER
Andreas Calatzis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
Pentapharm AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pentapharm AG filed Critical Pentapharm AG
Application granted granted Critical
Publication of DE60024669D1 publication Critical patent/DE60024669D1/de
Publication of DE60024669T2 publication Critical patent/DE60024669T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/4609—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates from reptiles
    • G01N2333/4613—Snake venom
    • G01N2333/4616—Snake venom from Russell's viper
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745—Assays involving non-enzymic blood coagulation factors
    • G01N2333/7456—Factor V
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433—Serine endopeptidases (3.4.21)
    • G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96444—Factor X (3.4.21.6)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE60024669T 1999-12-15 2000-12-14 Hämatologische bestimmung und reagenz Expired - Lifetime DE60024669T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
WOPCT/EP99/09952 1999-12-15
PCT/EP1999/009952 WO2001044493A2 (en) 1999-12-15 1999-12-15 Hematological assay and reagent
PCT/EP2000/012753 WO2001044819A2 (en) 1999-12-15 2000-12-14 Hematological assay and reagent

Publications (2)

Publication Number Publication Date
DE60024669D1 DE60024669D1 (de) 2006-01-12
DE60024669T2 true DE60024669T2 (de) 2006-09-28

Family

ID=8167528

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60024669T Expired - Lifetime DE60024669T2 (de) 1999-12-15 2000-12-14 Hämatologische bestimmung und reagenz

Country Status (9)

Country Link
US (1) US6994984B2 (enExample)
EP (1) EP1240528B1 (enExample)
JP (1) JP4762472B2 (enExample)
AT (1) ATE312352T1 (enExample)
AU (2) AU2431800A (enExample)
CA (1) CA2392350C (enExample)
DE (1) DE60024669T2 (enExample)
ES (1) ES2254260T3 (enExample)
WO (2) WO2001044493A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1918718A1 (de) * 2006-10-31 2008-05-07 Roche Diagnostics GmbH Verfahren und Vorrichtungen zur elektrochemischen Bestimmung von Faktor Xa-Inhibitoren in Blutproben

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US6680177B2 (en) * 2001-12-07 2004-01-20 Cardiovascular Diagnostics, Inc. Low molecular weight heparin assay, system and reagent therefor
US7358337B2 (en) * 2002-08-16 2008-04-15 International Technidyne Corporation Assay for low molecular weight heparin
ES2390271T3 (es) * 2003-09-22 2012-11-08 University Of North Carolina At Chapel Hill Fosfolípidos solubles para uso en ensayos de factores de coagulación
AU2005243161A1 (en) * 2004-05-11 2005-11-24 Heptest Laboratories, Inc. Compositions, kit and one-step method for monitoring compounds having anti-factor Xa and/or anti factor iia activities
GB2433592A (en) * 2005-12-23 2007-06-27 Pentapharm Ag Assay for thrombin inhibitors
EP2333555A1 (de) 2009-12-09 2011-06-15 Siemens Healthcare Diagnostics Products GmbH Heterogener Gerinnungstest
JP2011133396A (ja) * 2009-12-25 2011-07-07 Sysmex Corp 活性化部分トロンボプラスチン時間測定試薬、活性化部分トロンボプラスチン時間測定方法、及び血液凝固抑制物質の有無の判定方法
EP2484775A1 (de) * 2011-02-07 2012-08-08 Siemens Healthcare Diagnostics Products GmbH Heparin-insensitives Verfahren zur Bestimmung von direkten Gerinnungsfaktorinhibitoren
RU2517116C2 (ru) * 2012-07-03 2014-05-27 Государственное бюджетное учреждение Санкт-Петербургский научно-исследовательский институт скорой помощи им. И.И. Джанелидзе Способ оценки состояния свертывающей системы крови у пациентов, находящихся в критическом состоянии
EP3970738A1 (en) 2012-07-25 2022-03-23 Bioverativ Therapeutics Inc. Blood factor monitoring assay and uses thereof
US9651567B2 (en) 2013-05-14 2017-05-16 Cgt Enterprises, Llc Test strips for determining coagulation factor activities
US20160305966A1 (en) 2013-12-09 2016-10-20 Dsm Ip Assets B.V. Identification of anticoagulants in a sample
US10786553B2 (en) 2014-10-23 2020-09-29 Q-Sera Pty Ltd. Clotting composition
JP6873833B2 (ja) * 2017-06-09 2021-05-19 シスメックス株式会社 血液検体の判定方法、血液検体分析装置及びコンピュータプログラム
CA3078625C (en) 2017-10-09 2023-01-17 Terumo Bct Biotechnologies, Llc Lyophilization container and method of using same
CN109082458B (zh) * 2018-08-16 2024-02-23 上海原科实业发展有限公司 一种血栓弹力图法定量检测口服凝血因子Xa抑制剂试剂盒及其制备方法
CN108982865B (zh) * 2018-08-16 2021-05-11 上海原科实业发展有限公司 一种血栓弹力图法肝素定量检测试剂盒及其制备方法
CN109709344A (zh) * 2018-12-29 2019-05-03 贵州金玖生物技术有限公司 一种活化凝血检测试剂、其制备方法及其应用
CA3224729A1 (en) 2019-03-14 2020-09-17 Terumo Bct Biotechnologies, Llc Lyophilization loading tray assembly and system
CN110244066A (zh) * 2019-07-01 2019-09-17 北京乐普医疗科技有限责任公司 一种干式电化学法凝血酶原时间检测卡及制备方法
CN110887970B (zh) * 2019-11-29 2023-10-31 北京赛科希德科技股份有限公司 抽提缓冲液、兔脑抽提液、pt检测试剂及pt检测试剂盒
AU2021260947A1 (en) * 2020-04-24 2022-12-01 Perosphere Technologies Inc. Whole blood control sample systems and method of preparing and using the same
WO2022145477A1 (ja) * 2020-12-28 2022-07-07 藤森工業株式会社 血液凝固検査方法
EP4270010A4 (en) * 2020-12-28 2024-11-20 Fujimori Kogyo Co., Ltd. METHOD FOR EVALUATING BLOOD COAGULATION PERFORMANCE, AND METHOD FOR INSPECTING THROMBOSIS RISK
JP2024514307A (ja) 2021-03-31 2024-04-01 ヘモネティクス・コーポレーション 血液凝固測定装置の品質管理配合物
CN114703252B (zh) * 2022-06-02 2022-11-04 深圳市帝迈生物技术有限公司 一种用于检测血浆中水蛭素、比伐卢定、达比加群含量的试剂盒
WO2024163247A1 (en) * 2023-02-01 2024-08-08 Haemonetics Corporation Disposable cartridge for classification of anticoagulant and method of use

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3516579A1 (de) 1984-11-19 1986-05-22 Boehringer Mannheim Gmbh, 6800 Mannheim Gerinnungstest auf teststreifen
US4756884A (en) 1985-08-05 1988-07-12 Biotrack, Inc. Capillary flow device
US5164598A (en) 1985-08-05 1992-11-17 Biotrack Capillary flow device
US4946775A (en) 1985-09-05 1990-08-07 Yin E Thye Composition, kit and method for assaying heparin and a method for making the composition
DE3616496A1 (de) 1986-05-16 1987-11-19 Boehringer Mannheim Gmbh Analyseelement zur bestimmung von gerinnungsparametern
US5110727A (en) 1987-04-03 1992-05-05 Cardiovascular Diagnostics, Inc. Method for performing coagulation assays accurately, rapidly and simply, using dry chemical reagents and paramagnetic particles
US5266462A (en) * 1992-06-03 1993-11-30 Baxter Diagnostics Inc. Measurement of platelet activities
WO1999002992A1 (en) * 1997-07-11 1999-01-21 The Mount Sinai School Of Medicine Of The City University Of New York Assays for diagnosis of thrombophilic disease

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1918718A1 (de) * 2006-10-31 2008-05-07 Roche Diagnostics GmbH Verfahren und Vorrichtungen zur elektrochemischen Bestimmung von Faktor Xa-Inhibitoren in Blutproben
WO2008052718A1 (de) * 2006-10-31 2008-05-08 Roche Diagnostics Gmbh Verfahren und vorrichtungen zur elektrochemischen bestimmung von faktor xa-inhibitoren in blutproben

Also Published As

Publication number Publication date
EP1240528A2 (en) 2002-09-18
US20030104508A1 (en) 2003-06-05
CA2392350C (en) 2010-11-02
CA2392350A1 (en) 2001-06-21
ES2254260T3 (es) 2006-06-16
WO2001044819A3 (en) 2001-12-06
AU3159301A (en) 2001-06-25
DE60024669D1 (de) 2006-01-12
AU2431800A (en) 2001-06-25
EP1240528B1 (en) 2005-12-07
WO2001044493A2 (en) 2001-06-21
JP2003517610A (ja) 2003-05-27
US6994984B2 (en) 2006-02-07
AU776845B2 (en) 2004-09-23
ATE312352T1 (de) 2005-12-15
JP4762472B2 (ja) 2011-08-31
WO2001044819A2 (en) 2001-06-21

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Legal Events

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8327 Change in the person/name/address of the patent owner

Owner name: DSM IP ASSETS B.V., HEERLEN, NL