DE60020812T2 - Heteroaryl-substituierte chinolin-2-on derivate verwendbar als antikrebsmittel - Google Patents
Heteroaryl-substituierte chinolin-2-on derivate verwendbar als antikrebsmittel Download PDFInfo
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- DE60020812T2 DE60020812T2 DE60020812T DE60020812T DE60020812T2 DE 60020812 T2 DE60020812 T2 DE 60020812T2 DE 60020812 T DE60020812 T DE 60020812T DE 60020812 T DE60020812 T DE 60020812T DE 60020812 T2 DE60020812 T2 DE 60020812T2
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- Prior art keywords
- methyl
- aryl
- group
- substituents
- alkyl
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- 125000001424 substituent group Chemical group 0.000 claims description 125
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- 125000000217 alkyl group Chemical group 0.000 claims description 84
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- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- A61P13/08—Drugs for disorders of the urinary system of the prostate
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-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
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- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Communicable Diseases (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Virology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11970299P | 1999-02-11 | 1999-02-11 | |
| US119702P | 1999-02-11 | ||
| PCT/IB2000/000121 WO2000047574A1 (en) | 1999-02-11 | 2000-02-04 | Heteroaryl-substituted quinolin-2-one derivatives useful as anticancer agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60020812D1 DE60020812D1 (de) | 2005-07-21 |
| DE60020812T2 true DE60020812T2 (de) | 2006-05-04 |
Family
ID=22385869
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60020812T Expired - Lifetime DE60020812T2 (de) | 1999-02-11 | 2000-02-04 | Heteroaryl-substituierte chinolin-2-on derivate verwendbar als antikrebsmittel |
Country Status (39)
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-
2000
- 2000-02-04 BR BR0008202-3A patent/BR0008202A/pt not_active IP Right Cessation
- 2000-02-04 ES ES00901292T patent/ES2243228T3/es not_active Expired - Lifetime
- 2000-02-04 HU HU0105231A patent/HUP0105231A3/hu unknown
- 2000-02-04 PL PL00349839A patent/PL349839A1/xx not_active Application Discontinuation
- 2000-02-04 IL IL14430700A patent/IL144307A0/xx unknown
- 2000-02-04 OA OA1200100212A patent/OA11833A/en unknown
- 2000-02-04 KR KR1020017010187A patent/KR20010102073A/ko not_active Ceased
- 2000-02-04 DE DE60020812T patent/DE60020812T2/de not_active Expired - Lifetime
- 2000-02-04 ID IDW00200101724A patent/ID29584A/id unknown
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- 2000-02-04 AP APAP/P/2001/002241A patent/AP2001002241A0/en unknown
- 2000-02-04 HR HR20010574A patent/HRP20010574A2/hr not_active Application Discontinuation
- 2000-02-04 HK HK02104118.7A patent/HK1042096A1/zh unknown
- 2000-02-04 TR TR2002/01296T patent/TR200201296T2/xx unknown
- 2000-02-04 WO PCT/IB2000/000121 patent/WO2000047574A1/en not_active Ceased
- 2000-02-04 CN CN00803668A patent/CN1340051A/zh active Pending
- 2000-02-04 AT AT00901292T patent/ATE297916T1/de not_active IP Right Cessation
- 2000-02-04 TR TR2002/01297T patent/TR200201297T2/xx unknown
- 2000-02-04 AU AU21248/00A patent/AU2124800A/en not_active Abandoned
- 2000-02-04 CA CA002362394A patent/CA2362394C/en not_active Expired - Fee Related
- 2000-02-04 JP JP2000598494A patent/JP4090200B2/ja not_active Expired - Fee Related
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- 2000-02-09 DZ DZ000021A patent/DZ3009A1/xx active
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- 2000-02-09 US US09/501,163 patent/US6258824B1/en not_active Expired - Fee Related
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- 2000-02-10 GT GT200000014A patent/GT200000014A/es unknown
- 2000-02-10 PE PE2000000103A patent/PE20001464A1/es not_active Application Discontinuation
- 2000-02-10 PA PA20008490601A patent/PA8490601A1/es unknown
- 2000-02-10 AR ARP000100589A patent/AR028985A1/es not_active Application Discontinuation
- 2000-02-10 SV SV2000000020A patent/SV2001000020A/es not_active Application Discontinuation
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2001
- 2001-04-17 US US09/836,026 patent/US6388092B2/en not_active Expired - Fee Related
- 2001-07-10 IS IS5997A patent/IS5997A/is unknown
- 2001-08-08 ZA ZA200106520A patent/ZA200106520B/en unknown
- 2001-08-10 NO NO20013909A patent/NO20013909L/no not_active Application Discontinuation
- 2001-08-30 BG BG105860A patent/BG105860A/xx unknown
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2002
- 2002-03-07 US US10/092,744 patent/US6710209B2/en not_active Expired - Fee Related
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2004
- 2004-02-05 JP JP2004029709A patent/JP4216740B2/ja not_active Expired - Fee Related
- 2004-07-20 JP JP2004211298A patent/JP2005002124A/ja active Pending
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