TR200201296T2 - Antikanser maddeleri olarak faydalı heteroaril-ikame edilmiş kinolin-2-on türevleri - Google Patents

Antikanser maddeleri olarak faydalı heteroaril-ikame edilmiş kinolin-2-on türevleri

Info

Publication number
TR200201296T2
TR200201296T2 TR2002/01296T TR200201296T TR200201296T2 TR 200201296 T2 TR200201296 T2 TR 200201296T2 TR 2002/01296 T TR2002/01296 T TR 2002/01296T TR 200201296 T TR200201296 T TR 200201296T TR 200201296 T2 TR200201296 T2 TR 200201296T2
Authority
TR
Turkey
Prior art keywords
heteroaryl
compounds
formula
anticancer agents
derivatives useful
Prior art date
Application number
TR2002/01296T
Other languages
English (en)
Inventor
Vera Yang Bingwei
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of TR200201296T2 publication Critical patent/TR200201296T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Abstract

Mevcut bulus, R ,R ,R ,R4,R5,R6,R7,R8,R9 ve Z'nin burada tanimlandigi gibi oldugu formül (I)'e ait bilesiklerle ve bunun farmasötik açidan kabul gören tuzlari ve solvatlariyla ilgilidir. Bulus, formül (I)'e ait bilesikleri ihtiva eden farmasötik kompozisyonlarla ve formül (I)'e ait bilesiklerin memeliye uygulanmasi suretiyle bir memelide kanser dahil anormal hücre büyümesinin önlenmesine yönelik metotlarla da ilgilidir. Bulus, formül (I)'e ait bilesiklerin sentezlenmesinde faydali ara baglar ve metotlarla da ilgilidir.
TR2002/01296T 1999-02-11 2000-02-04 Antikanser maddeleri olarak faydalı heteroaril-ikame edilmiş kinolin-2-on türevleri TR200201296T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11970299P 1999-02-11 1999-02-11

Publications (1)

Publication Number Publication Date
TR200201296T2 true TR200201296T2 (tr) 2002-07-22

Family

ID=22385869

Family Applications (2)

Application Number Title Priority Date Filing Date
TR2002/01296T TR200201296T2 (tr) 1999-02-11 2000-02-04 Antikanser maddeleri olarak faydalı heteroaril-ikame edilmiş kinolin-2-on türevleri
TR2002/01297T TR200201297T2 (tr) 1999-02-11 2000-02-04 Antikanser maddeleri olarak faydalı heteroaril-ikame edilmiş kinolin-2-on türevleri.

Family Applications After (1)

Application Number Title Priority Date Filing Date
TR2002/01297T TR200201297T2 (tr) 1999-02-11 2000-02-04 Antikanser maddeleri olarak faydalı heteroaril-ikame edilmiş kinolin-2-on türevleri.

Country Status (39)

Country Link
US (3) US6258824B1 (tr)
EP (1) EP1150973B1 (tr)
JP (3) JP4090200B2 (tr)
KR (1) KR20010102073A (tr)
CN (1) CN1340051A (tr)
AP (1) AP2001002241A0 (tr)
AR (1) AR028985A1 (tr)
AT (1) ATE297916T1 (tr)
AU (1) AU2124800A (tr)
BG (1) BG105860A (tr)
BR (1) BR0008202A (tr)
CA (1) CA2362394C (tr)
CO (1) CO5140097A1 (tr)
CZ (1) CZ20012910A3 (tr)
DE (1) DE60020812T2 (tr)
DZ (1) DZ3009A1 (tr)
EA (1) EA200100766A1 (tr)
EE (1) EE200100425A (tr)
ES (1) ES2243228T3 (tr)
GT (1) GT200000014A (tr)
HK (1) HK1042096A1 (tr)
HN (1) HN2000000019A (tr)
HR (1) HRP20010574A2 (tr)
HU (1) HUP0105231A3 (tr)
ID (1) ID29584A (tr)
IL (1) IL144307A0 (tr)
IS (1) IS5997A (tr)
MA (1) MA26718A1 (tr)
NO (1) NO20013909L (tr)
OA (1) OA11833A (tr)
PA (1) PA8490601A1 (tr)
PE (1) PE20001464A1 (tr)
PL (1) PL349839A1 (tr)
SK (1) SK11002001A3 (tr)
SV (1) SV2001000020A (tr)
TN (1) TNSN00028A1 (tr)
TR (2) TR200201296T2 (tr)
WO (1) WO2000047574A1 (tr)
ZA (1) ZA200106520B (tr)

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GT200000014A (es) 2001-08-03
HUP0105231A2 (hu) 2002-04-29
NO20013909L (no) 2001-10-08
TNSN00028A1 (fr) 2005-11-10
JP4090200B2 (ja) 2008-05-28
CN1340051A (zh) 2002-03-13
DE60020812D1 (de) 2005-07-21
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