DE60011560T2 - Salmonella Impfstoff, der keinen Antikörper gegen Flagellin oder gegen Flagella induziert - Google Patents

Salmonella Impfstoff, der keinen Antikörper gegen Flagellin oder gegen Flagella induziert Download PDF

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Publication number
DE60011560T2
DE60011560T2 DE60011560T DE60011560T DE60011560T2 DE 60011560 T2 DE60011560 T2 DE 60011560T2 DE 60011560 T DE60011560 T DE 60011560T DE 60011560 T DE60011560 T DE 60011560T DE 60011560 T2 DE60011560 T2 DE 60011560T2
Authority
DE
Germany
Prior art keywords
flagellin
vaccine
flagella
salmonella
bacterium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60011560T
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German (de)
English (en)
Other versions
DE60011560D1 (de
Inventor
Petrus Johannes Maria Nuijten
Maarten Hendrik Witvliet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Intervet International BV
Original Assignee
Akzo Nobel NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel NV filed Critical Akzo Nobel NV
Publication of DE60011560D1 publication Critical patent/DE60011560D1/de
Application granted granted Critical
Publication of DE60011560T2 publication Critical patent/DE60011560T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0275—Salmonella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE60011560T 1999-12-28 2000-12-19 Salmonella Impfstoff, der keinen Antikörper gegen Flagellin oder gegen Flagella induziert Expired - Lifetime DE60011560T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99204564 1999-12-28
EP99204564 1999-12-28

Publications (2)

Publication Number Publication Date
DE60011560D1 DE60011560D1 (de) 2004-07-22
DE60011560T2 true DE60011560T2 (de) 2005-08-18

Family

ID=8241112

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60011560T Expired - Lifetime DE60011560T2 (de) 1999-12-28 2000-12-19 Salmonella Impfstoff, der keinen Antikörper gegen Flagellin oder gegen Flagella induziert

Country Status (15)

Country Link
US (2) US20010021386A1 (enExample)
EP (1) EP1112747B1 (enExample)
JP (1) JP5745731B2 (enExample)
AT (1) ATE269104T1 (enExample)
AU (1) AU783508B2 (enExample)
BR (1) BR0006291B1 (enExample)
CA (1) CA2329676A1 (enExample)
DE (1) DE60011560T2 (enExample)
DK (1) DK1112747T3 (enExample)
ES (1) ES2222152T3 (enExample)
HU (1) HU226192B1 (enExample)
MX (1) MXPA00012796A (enExample)
PL (1) PL206377B1 (enExample)
PT (1) PT1112747E (enExample)
TR (1) TR200401569T4 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4751570B2 (ja) * 2002-09-11 2011-08-17 東レ・ダウコーニング株式会社 オルガノポリシロキサン変性多糖類およびその製造方法
EP2517723B1 (en) 2006-09-18 2019-11-06 The Board of Trustees of The University of Arkansas Compositions and methods of enhancing immune responses
US7935355B2 (en) * 2007-04-19 2011-05-03 Nutritional Health Institute Laboratories, Llc Composition and method for controlling intestinal pathogenic organisms
US20080260777A1 (en) * 2007-04-19 2008-10-23 Sotomayor Konky Composition and method for controlling intestinal pathogenic organisms
BRPI0818736A2 (pt) * 2007-10-30 2017-06-13 Univ Arkansas composições e métodos para intensificar imunorrepostas à bactéria flagelada
WO2009059298A2 (en) 2007-11-01 2009-05-07 Board Of Trustees Of The University Of Arkansas Compositions and methods of enhancinc immune responses to eimeria
CA2703519C (en) 2007-11-09 2017-04-18 The Salk Institute For Biological Studies Use of tam receptor inhibitors as immunoenhancers and tam activators as immunosuppressors
CN102811734B (zh) 2010-01-21 2016-02-10 阿肯色大学评议会 增强免疫应答的疫苗载体和方法
CA2800830C (en) 2010-06-09 2020-09-08 The Board Of Trustees Of The University Of Arkansas Vaccine and methods to reduce campylobacter infection
KR101449417B1 (ko) 2012-06-20 2014-10-27 한국외국어대학교 연구산학협력단 살모넬라 엔테리카의 박테리오파아지 및 그 용도
WO2014097154A1 (en) 2012-12-20 2014-06-26 Zakład Badawczo-Wdrożeniowy Ośrodka Salmonella "Immunolab" Sp. Z O.O. A polyvalent combined immunising and/or therapeutic preparation for use in bacterial infections or food poisoning, particularly salmonellosis, a method for production of this preparation, its use and a vaccine comprising this preparation
HUE047484T2 (hu) 2013-02-14 2020-04-28 Univ Arkansas Készítmények és eljárások eimeria elleni immunválasz fokozására vagy eimeria-fertõzés korlátozására
US9845341B2 (en) 2013-03-11 2017-12-19 The Brigham And Women's Hospital, Inc. Vibro-based delivery system and immune suppression
US10376571B2 (en) 2013-03-15 2019-08-13 The Board Of Trustees Of The University Of Arkansas Compositions and methods of enhancing immune responses to enteric pathogens
KR20190015712A (ko) 2016-05-03 2019-02-14 더 보드 오브 트러스티스 오브 더 유니버시티 오브 아칸소 면역자극 및 항원 폴리펩티드를 포함하는 효모 백신 벡터, 및 그를 이용하는 방법
CN111374094B (zh) * 2020-03-02 2022-04-19 扬州大学 驴源马流产沙门氏菌经皮下致非妊娠期小鼠子宫感染模型的建立方法
CN118773056B (zh) * 2024-07-10 2025-07-08 山东省滨州畜牧兽医研究院 一种马流产沙门氏菌灭活疫苗

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1109179A (en) * 1964-09-30 1968-04-10 Nat Res Dev Improvements relating to typhoid and paratyphoid vaccines
ES2060580T3 (es) * 1986-03-11 1994-12-01 Shionogi & Co Adn que tiene una secuencia adn codificante de la proteina flagelina y vector que la contiene.
US6130082A (en) * 1988-05-05 2000-10-10 American Cyanamid Company Recombinant flagellin vaccines
DE68922394T2 (de) * 1988-05-05 1995-10-05 Praxis Biolog Inc Rekombinante vakzine von flagellin.
AU640118B2 (en) * 1988-12-19 1993-08-19 De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezonheid En Cultuur Meningococcal class 1 outer-membrane protein vaccine
DK0744937T3 (da) * 1994-02-18 2002-10-28 Solidose L L C Vaccination af dyr med tørrede, pelleterede biologiske materialer
GB9621091D0 (en) * 1996-10-09 1996-11-27 Fondation Pour Le Perfectionem Attenuated microorganisms strains and their uses
US6190669B1 (en) * 1998-05-13 2001-02-20 University Of Maryland, Baltimore Attenuated mutants of salmonella which constitutively express the Vi antigen

Also Published As

Publication number Publication date
EP1112747A1 (en) 2001-07-04
BR0006291A (pt) 2001-11-27
PL206377B1 (pl) 2010-08-31
JP5745731B2 (ja) 2015-07-08
ATE269104T1 (de) 2004-07-15
HUP0005010A2 (en) 2002-06-29
HU0005010D0 (enExample) 2001-02-28
PT1112747E (pt) 2004-10-29
ES2222152T3 (es) 2005-02-01
MXPA00012796A (es) 2002-05-23
US20080069843A1 (en) 2008-03-20
JP2001186874A (ja) 2001-07-10
HU226192B1 (en) 2008-06-30
DE60011560D1 (de) 2004-07-22
EP1112747B1 (en) 2004-06-16
CA2329676A1 (en) 2001-06-28
AU783508B2 (en) 2005-11-03
BR0006291B1 (pt) 2014-02-18
PL344851A1 (en) 2001-07-02
DK1112747T3 (da) 2004-10-25
US20010021386A1 (en) 2001-09-13
AU7245300A (en) 2001-07-05
TR200401569T4 (tr) 2004-07-21
HUP0005010A3 (en) 2004-07-28

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Owner name: INTERVET INTERNATIONAL B. V., AN BOXMEER, NL