DE59609627D1 - Neue stabile arzneimittelzubereitung zur erzeugung treibgasfreier aerosole - Google Patents

Neue stabile arzneimittelzubereitung zur erzeugung treibgasfreier aerosole

Info

Publication number
DE59609627D1
DE59609627D1 DE59609627T DE59609627T DE59609627D1 DE 59609627 D1 DE59609627 D1 DE 59609627D1 DE 59609627 T DE59609627 T DE 59609627T DE 59609627 T DE59609627 T DE 59609627T DE 59609627 D1 DE59609627 D1 DE 59609627D1
Authority
DE
Germany
Prior art keywords
gas
production
drug preparation
new stable
stable drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE59609627T
Other languages
German (de)
English (en)
Inventor
Bernhard Freund
Michael Krueger
Bernd Zierenberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Boehringer Ingelheim Pharma GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7765285&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE59609627(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma GmbH and Co KG filed Critical Boehringer Ingelheim Pharma GmbH and Co KG
Priority to DE59609627T priority Critical patent/DE59609627D1/de
Application granted granted Critical
Publication of DE59609627D1 publication Critical patent/DE59609627D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE59609627T 1995-06-27 1996-06-21 Neue stabile arzneimittelzubereitung zur erzeugung treibgasfreier aerosole Expired - Lifetime DE59609627D1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE59609627T DE59609627D1 (de) 1995-06-27 1996-06-21 Neue stabile arzneimittelzubereitung zur erzeugung treibgasfreier aerosole

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19523207 1995-06-27
PCT/EP1996/002700 WO1997001329A1 (de) 1995-06-27 1996-06-21 Neue stabile arzneimittelzubereitung zur erzeugung treibgasfreier aerosole
DE59609627T DE59609627D1 (de) 1995-06-27 1996-06-21 Neue stabile arzneimittelzubereitung zur erzeugung treibgasfreier aerosole

Publications (1)

Publication Number Publication Date
DE59609627D1 true DE59609627D1 (de) 2002-10-10

Family

ID=7765285

Family Applications (2)

Application Number Title Priority Date Filing Date
DE59609627T Expired - Lifetime DE59609627D1 (de) 1995-06-27 1996-06-21 Neue stabile arzneimittelzubereitung zur erzeugung treibgasfreier aerosole
DE19625027A Ceased DE19625027A1 (de) 1995-06-27 1996-06-21 Neue stabile Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE19625027A Ceased DE19625027A1 (de) 1995-06-27 1996-06-21 Neue stabile Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole

Country Status (35)

Country Link
US (5) US6491897B1 (zh)
EP (1) EP0835098B1 (zh)
JP (1) JP3875993B2 (zh)
KR (1) KR100392280B1 (zh)
CN (1) CN1086575C (zh)
AR (1) AR002614A1 (zh)
AT (1) ATE223203T1 (zh)
AU (1) AU721566B2 (zh)
BG (1) BG64112B1 (zh)
BR (1) BR9609307B1 (zh)
CA (1) CA2225601C (zh)
CZ (1) CZ288337B6 (zh)
DE (2) DE59609627D1 (zh)
DK (1) DK0835098T3 (zh)
EE (1) EE03509B2 (zh)
EG (1) EG23912A (zh)
ES (1) ES2183001T3 (zh)
HU (1) HU223072B1 (zh)
IL (1) IL122752A (zh)
MX (1) MX9800125A (zh)
MY (1) MY116535A (zh)
NO (1) NO315452B1 (zh)
NZ (1) NZ312662A (zh)
PE (1) PE11098A1 (zh)
PL (1) PL186196B1 (zh)
PT (1) PT835098E (zh)
RU (1) RU2223750C2 (zh)
SA (1) SA96170213B1 (zh)
SI (1) SI0835098T1 (zh)
SK (1) SK282468B6 (zh)
TR (1) TR199701711T1 (zh)
TW (1) TW537903B (zh)
UA (1) UA62917C2 (zh)
WO (1) WO1997001329A1 (zh)
ZA (1) ZA965411B (zh)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9504265D0 (en) * 1995-03-03 1995-04-19 Medeva Plc Corticosteroid-containing pharmaceutical composition
KR100392280B1 (ko) 1995-06-27 2003-11-19 베링거 인겔하임 카게 추진제비함유흡입성에어로졸을제조하기위한안정한추진제비함유약제학적용액
US20030215396A1 (en) * 1999-09-15 2003-11-20 Boehringer Ingelheim Pharma Kg Method for the production of propellant gas-free aerosols from aqueous medicament preparations
DE19653969A1 (de) * 1996-12-20 1998-06-25 Boehringer Ingelheim Kg Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole
US6598603B1 (en) * 1997-12-31 2003-07-29 Astra Aktiebolag Method for treating respiratory diseases
DE19808295A1 (de) 1998-02-27 1999-11-11 Boehringer Ingelheim Int Behälter für eine medizinische Flüssigkeit
DE19847968A1 (de) 1998-10-17 2000-04-20 Boehringer Ingelheim Pharma Verschlußkappe und Behälter als Zweikammer-Kartusche für Vernebler zur Erzeugung von Aerosolen
DE19940713A1 (de) 1999-02-23 2001-03-01 Boehringer Ingelheim Int Kartusche für eine Flüssigkeit
GB9904281D0 (en) * 1999-02-24 1999-04-21 Reneuron Ltd Transplantation
DE19954516A1 (de) * 1999-11-12 2001-05-17 Boehringer Ingelheim Int Epinastin-haltige Lösungen
US8820316B2 (en) * 2000-02-11 2014-09-02 Respironics Respiratory Drug Delivery (Uk) Ltd Drug delivery apparatus
GB0009583D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Respiratory formulations
US20020111363A1 (en) * 2000-10-31 2002-08-15 Karin Drechsel Inhalable formulation of a solution containing a tiotropium salt
US20020137764A1 (en) * 2000-10-31 2002-09-26 Karin Drechsel Inhalable formulation of a solution containing a tiotropium salt
EP1335729A2 (de) * 2000-10-31 2003-08-20 Boehringer Ingelheim Pharma GmbH & Co.KG Inhalative lösungsformulierung mit einem tiotropiumsalz
DE10062712A1 (de) * 2000-12-15 2002-06-20 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und Corticosteroiden
US20020193392A1 (en) * 2000-11-13 2002-12-19 Christel Schmelzer Pharmaceutical compositions based on tiotropium salts of salts of salmeterol
DE10111843A1 (de) * 2001-03-13 2002-09-19 Boehringer Ingelheim Pharma Verbindungen zur Behandlung von inflammatorischen Erkrankungen
DE10130371A1 (de) * 2001-06-23 2003-01-02 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika, Corticosteroiden und Betamimetika
DE10136555A1 (de) 2001-07-27 2003-02-13 Boehringer Ingelheim Int Optimierte Verfahren zur Bestimmung der Aerosol-Partikelgrößenverteilung und Vorrichtung zur Durchführung derartiger Verfahren
US20040019073A1 (en) * 2002-04-11 2004-01-29 Boehringer Ingelheim Pharma Gmbh Co. Kg Aerosol formulation for inhalation containing a tiotropium salt
US20040166065A1 (en) * 2002-08-14 2004-08-26 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosol formulation for inhalation comprising an anticholinergic
US7040314B2 (en) 2002-09-06 2006-05-09 Philip Morris Usa Inc. Aerosol generating devices and methods for generating aerosols suitable for forming propellant-free aerosols
US7056916B2 (en) 2002-11-15 2006-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments for the treatment of chronic obstructive pulmonary disease
US7849850B2 (en) * 2003-02-28 2010-12-14 Battelle Memorial Institute Nozzle for handheld pulmonary aerosol delivery device
DE10345065A1 (de) 2003-09-26 2005-04-14 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
AR041873A1 (es) * 2003-10-30 2005-06-01 Pablo Cassara Srl Lab Una formulacion farmaceutica en aerosol adecuada para la inhalacion oral o nasal que contienen glucocorticoides en solucion estable al almacenamiento; un metodo para estabilzar formulaciones y uso de un agente estabilizante
DE102004001451A1 (de) 2004-01-08 2005-08-11 Boehringer Ingelheim International Gmbh Vorrichtung zum Haltern eines fluidischen Bauteiles
US7220742B2 (en) 2004-05-14 2007-05-22 Boehringer Ingelheim International Gmbh Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
GB0427568D0 (en) * 2004-12-16 2005-01-19 Resolution Chemicals Ltd Particle-size reduction apparatus, and the use thereof
EP1848270B1 (en) 2005-02-17 2014-05-21 Abbott Laboratories Transmucosal administration of drug compositions for treating and preventing disorders in animals
MX2007010396A (es) * 2005-02-25 2007-10-19 Chiesi Farma Spa Formulaciones farmaceuticas en aerosol para inhaladores presurizados de dosis medida que comprenden un agente secuestrante.
ES2530991T3 (es) 2005-08-15 2015-03-09 Boehringer Ingelheim Int Procedimiento para la obtención de betamiméticos
TWI396541B (zh) * 2005-10-10 2013-05-21 Boehringer Ingelheim Int 用於治療呼吸疾病之新穎藥物組合
AU2006338191B2 (en) 2006-02-14 2011-06-30 Battelle Memorial Institute Dissociated discharge EHD sprayer with electric field shield
DE102006023756A1 (de) * 2006-05-20 2007-11-29 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ethanolhaltige Aerosolformulierung für die Inhalation
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
JP2012506860A (ja) * 2008-10-23 2012-03-22 サノビオン ファーマシューティカルズ インク アルホルモテロール及びチオトロピウムの組成物及びその使用方法
US10011906B2 (en) 2009-03-31 2018-07-03 Beohringer Ingelheim International Gmbh Method for coating a surface of a component
EP3508239B1 (de) 2009-05-18 2020-12-23 Boehringer Ingelheim International GmbH Adapter, inhalationseinrichtung und zerstäuber
WO2011064163A1 (en) 2009-11-25 2011-06-03 Boehringer Ingelheim International Gmbh Nebulizer
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
UA107097C2 (en) 2009-11-25 2014-11-25 Бьорінгер Інгельхайм Інтернаціональ Гмбх Dispenser
JP5874724B2 (ja) 2010-06-24 2016-03-02 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
EP2694220B1 (de) 2011-04-01 2020-05-06 Boehringer Ingelheim International GmbH Medizinisches gerät mit behälter
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
EP3030298B1 (en) 2013-08-09 2017-10-11 Boehringer Ingelheim International GmbH Nebulizer
ES2836977T3 (es) 2013-08-09 2021-06-28 Boehringer Ingelheim Int Nebulizador
UA121114C2 (uk) 2014-05-07 2020-04-10 Бьорінгер Інгельхайм Інтернаціональ Гмбх Небулайзер, індикаторний пристрій і контейнер
ES2874029T3 (es) 2014-05-07 2021-11-04 Boehringer Ingelheim Int Nebulizador
ES2954961T3 (es) 2014-05-07 2023-11-27 Boehringer Ingelheim Int Unidad, nebulizador y método
US10603451B2 (en) 2014-11-20 2020-03-31 Boehringer Ingelheim Vetmedica Gmbh Container for an inhaler
CN111939143A (zh) * 2019-05-16 2020-11-17 鲁南制药集团股份有限公司 一种布地奈德溶液型气雾剂及其制备方法
KR102278414B1 (ko) 2019-12-03 2021-07-16 한전케이피에스 주식회사 벨트 교체용 공구
AU2021314977A1 (en) 2020-07-31 2023-03-02 Chemo Research, S.L. Combination therapy for inhalation administration

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE632504A (zh) 1962-05-24
DE1952320C3 (de) 1969-10-17 1981-02-26 Licentia Patent-Verwaltungs-Gmbh, 6000 Frankfurt Vorrichtung zum Abdichten von zwei koaxial ineinander gelagerten um- oder gegenläufigen Wellen bei Wasserfahrzeugen
MX3864E (es) * 1975-05-27 1981-08-26 Syntex Corp Un proceso para prepara el compuesto cristalino 6-fluiro-11b 21-dihiroxi-16 17-isopropilidendioxipregna-1 4-dien-3 20-diona
JPS5529524A (en) 1978-08-21 1980-03-01 Toyo Aerosol Kogyo Kk Powdery aerosol composition
JPS599539B2 (ja) 1979-11-13 1984-03-03 日本化薬株式会社 ニトログリセリン水溶液及びその製造法
US4289764A (en) * 1979-12-04 1981-09-15 Drythanol Ltd. Steroid compositions
DE3109783A1 (de) 1981-03-13 1982-10-07 Sanol Schwarz-Monheim Gmbh, 4019 Monheim Mit wasser zu einer etwa isotonischen nitroglycerinloesung aufloesbare zubereitung und derartige nitroglycerinloesung
US4383992A (en) * 1982-02-08 1983-05-17 Lipari John M Water-soluble steroid compounds
DE3246081A1 (de) 1982-12-13 1984-06-14 G. Pohl-Boskamp GmbH & Co Chemisch-pharmazeutische Fabrik, 2214 Hohenlockstedt Nitroglycerin-spray
JPS6183117A (ja) 1984-09-28 1986-04-26 Sumitomo Chem Co Ltd エアゾ−ル剤
US4615699A (en) 1985-05-03 1986-10-07 Alza Corporation Transdermal delivery system for delivering nitroglycerin at high transdermal fluxes
DE3544692A1 (de) 1985-12-18 1987-06-19 Bayer Ag Dihydropyridinspray, verfahren zu seiner herstellung und seine pharmazeutische verwendung
AU6907687A (en) * 1986-02-18 1987-08-20 Rorer Pharmaceutical Corporation Composition for treatment of asthmatic conditions using phenoxymethyl quinolines
JPH0645538B2 (ja) 1987-09-30 1994-06-15 日本化薬株式会社 ニトログリセリンスプレー剤
HU199678B (en) * 1988-07-08 1990-03-28 Egyt Gyogyszervegyeszeti Gyar Process for producing aerosols containing nitroglicerol
GB8828477D0 (en) * 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
US5225183A (en) * 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
US5136124A (en) 1988-12-14 1992-08-04 International Business Machines Corporation Method of forming conductors within an insulating substrate
GB8829478D0 (en) 1988-12-16 1989-02-01 Harris Pharma Ltd Formulations
US5370862A (en) * 1990-06-13 1994-12-06 Schwarz Pharma Ag Pharmaceutical hydrophilic spray containing nitroglycerin for treating angina
IT1243379B (it) 1990-07-27 1994-06-10 Giuliani Spa Composizione farmaceutica adatta alla somministrazione rettale di principi attivi che esplicano un'azione di medicazione a livello del colon prevalentemente di tipo topico
MX9203481A (es) * 1990-10-18 1992-07-01 Minnesota Mining & Mfg Formulaciones.
CA2094266C (en) * 1990-10-18 1999-06-01 Robert K. Schultz Aerosol formulations of beclomethasone-17,21-dipropionate
EP0504112A3 (en) 1991-03-14 1993-04-21 Ciba-Geigy Ag Pharmaceutical aerosol formulations
PT656207E (pt) * 1991-06-10 2001-11-30 Schering Corp Formulacoes de aerossois sem clorofluorocarbonetos
DE4123663A1 (de) * 1991-07-17 1993-01-21 Schwabe Willmar Gmbh & Co Aerosol-zubereitung und verwendung eines treibmittels dafuer
IL103238A (en) 1991-09-25 1995-07-31 Fisons Plc Pressed aerosol preparations
US5736124A (en) * 1991-12-12 1998-04-07 Glaxo Group Limited Aerosol formulations containing P134a and particulate medicament
US5674471A (en) * 1991-12-12 1997-10-07 Glaxo Group Limited Aerosol formulations containing P134a and salbutamol
GB9202519D0 (en) 1992-02-06 1992-03-25 Glaxo Group Ltd Medicaments
DE4203306A1 (de) 1992-02-06 1993-08-12 Ig Spruehtechnik Gmbh Asthma oder pulmonal-aerosolzubereitungen mit lecithin
US5224183A (en) * 1992-07-23 1993-06-29 Alcatel Network Systems, Inc. Multiple wavelength division multiplexing signal compensation system and method using same
WO1994013262A1 (en) * 1992-12-09 1994-06-23 Boehringer Ingelheim Pharmaceuticals, Inc. Stabilized medicinal aerosol solution formulations
DE4340057A1 (de) 1993-11-24 1995-06-01 Falk Pharma Gmbh Budesonid-Arzneimittel zur Verbesserung der enteralen Flüssigkeitsresorption, insbesondere nach postoperativen Zuständen
DE4446891A1 (de) * 1994-12-27 1996-07-04 Falk Pharma Gmbh Stabile wäßrige Budesonid-Lösung
KR100392280B1 (ko) 1995-06-27 2003-11-19 베링거 인겔하임 카게 추진제비함유흡입성에어로졸을제조하기위한안정한추진제비함유약제학적용액
US5958378A (en) * 1996-07-03 1999-09-28 Research Development Foundation High dose liposomal aerosol formulations containing cyclosporin A or budesonide
US6039932A (en) * 1996-09-27 2000-03-21 3M Innovative Properties Company Medicinal inhalation aerosol formulations containing budesonide
US6004537A (en) * 1998-12-18 1999-12-21 Baker Norton Pharmaceuticals, Inc. Pharmaceutical solution aerosol formulations containing fluoroalkanes, budesonide and formoterol
US20020137764A1 (en) * 2000-10-31 2002-09-26 Karin Drechsel Inhalable formulation of a solution containing a tiotropium salt

Also Published As

Publication number Publication date
MY116535A (en) 2004-02-28
EE9700371A (et) 1998-06-15
ATE223203T1 (de) 2002-09-15
JP3875993B2 (ja) 2007-01-31
US6491897B1 (en) 2002-12-10
CA2225601A1 (en) 1997-01-16
US20020141944A1 (en) 2002-10-03
SK176497A3 (en) 1998-06-03
TW537903B (en) 2003-06-21
JPH11508547A (ja) 1999-07-27
BG102172A (en) 1998-10-30
CZ419297A3 (cs) 1998-06-17
US20030165435A1 (en) 2003-09-04
CA2225601C (en) 2003-10-14
HU223072B1 (hu) 2004-03-01
BR9609307A (pt) 1999-07-06
CN1189096A (zh) 1998-07-29
WO1997001329A1 (de) 1997-01-16
NO315452B1 (no) 2003-09-08
AR002614A1 (es) 1998-03-25
PL186196B1 (pl) 2003-11-28
AU6414496A (en) 1997-01-30
PE11098A1 (es) 1998-03-17
EG23912A (en) 2007-12-30
EE03509B2 (et) 2015-02-16
EE03509B1 (et) 2001-10-15
KR100392280B1 (ko) 2003-11-19
IL122752A0 (en) 1998-08-16
BR9609307B1 (pt) 2010-03-09
EP0835098B1 (de) 2002-09-04
PT835098E (pt) 2002-12-31
SI0835098T1 (en) 2003-02-28
KR19990028408A (ko) 1999-04-15
IL122752A (en) 2001-07-24
US20060127322A1 (en) 2006-06-15
SK282468B6 (sk) 2002-02-05
UA62917C2 (en) 2004-01-15
ZA965411B (en) 1996-12-27
US8062626B2 (en) 2011-11-22
TR199701711T1 (xx) 1998-05-21
EP0835098A1 (de) 1998-04-15
CZ288337B6 (en) 2001-05-16
ES2183001T3 (es) 2003-03-16
DE19625027A1 (de) 1997-01-02
AU721566B2 (en) 2000-07-06
DK0835098T3 (da) 2002-10-07
NZ312662A (en) 2001-03-30
RU2223750C2 (ru) 2004-02-20
CN1086575C (zh) 2002-06-26
NO976084D0 (no) 1997-12-23
SA96170213B1 (ar) 2006-03-06
HUP9901710A2 (hu) 1999-10-28
PL324243A1 (en) 1998-05-11
US20080102037A1 (en) 2008-05-01
MX9800125A (es) 1998-03-31
HUP9901710A3 (en) 2000-06-28
NO976084L (no) 1997-12-23
BG64112B1 (bg) 2004-01-30

Similar Documents

Publication Publication Date Title
DE59609627D1 (de) Neue stabile arzneimittelzubereitung zur erzeugung treibgasfreier aerosole
DE59709722D1 (de) Verwendung von wässerigen arzneimittelzubereitungen zur erzeugung treibgasfreier aerosole
DE59600851D1 (de) Verfahren zur Herstellung mikromechanischer Bauelemente
ATE233241T1 (de) Stabile reagenzien zur herstellung von radiopharmazeutika
DE69637263D1 (de) System zur Erzeugung von Probeauszügen
DK0770615T3 (da) Fremgangsmåde til fremstilling af dihalogenazolopyrimidiner
DE69621491D1 (de) Verfahren zur Herstellung von Epsilon-Caprolactam
DE69830754D1 (de) Verfahren zur Herstellung von Monofluoromethylether
DE59607656D1 (de) Verfahren zur Herstellung von Alkylhydrogenchlorsilanen
DE69808569D1 (de) Verfahren zur Herstellung von keramischen Pulvern
DE69636776D1 (de) Verfahren zur herstellung von etherderivaten
DE69833205D1 (de) Verfahren zur herstellung von heparin
DE69805381T2 (de) Vorrichtung zur Herstellung von synthethischem Quarzglas
DE59709470D1 (de) Verfahren zur kontinuierlichen Herstellung von 3-Halogen-Propyl-Organosilanen
DE59601030D1 (de) Verfahren zur Herstellung von Diarylethanen
DE59501841D1 (de) Verfahren zur Herstellung von Glutardialdehyd
DE69600385T2 (de) Verfahren zur Herstellung von Aminonitropyridinen
DE59605105D1 (de) Verfahren zur Herstellung von substituierten Aminocarbonyltriazolinonen
DE69733524D1 (de) Verfahren zur Herstellung von Dihydropyranverbindungen
DE69513008D1 (de) Verfahren zur Herstellung von Hydroxyalkoxybenzophenonen
DE69607541D1 (de) Verfahren zur Herstellung von p-Bromfluorobenzol
DE59811275D1 (de) Verfahren zur Herstellung von Akustik-Bauteilen
DE69509082D1 (de) Verfahren zur Herstellung von Oligomeren von Mono-Olefinen
DK0821697T3 (da) Fremgangsmåde til fremstilling af streptograminer
DE69840019D1 (de) Verfahren zur Herstellung von Erythritol

Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: BOEHRINGER INGELHEIM PHARMA GMBH & CO.KG, 55218 IN