DE4329970A1 - Neue Imidazolo-chinoxalinone, ihre Hestellung und Verwendung - Google Patents

Neue Imidazolo-chinoxalinone, ihre Hestellung und Verwendung

Info

Publication number
DE4329970A1
DE4329970A1 DE4329970A DE4329970A DE4329970A1 DE 4329970 A1 DE4329970 A1 DE 4329970A1 DE 4329970 A DE4329970 A DE 4329970A DE 4329970 A DE4329970 A DE 4329970A DE 4329970 A1 DE4329970 A1 DE 4329970A1
Authority
DE
Germany
Prior art keywords
oxo
dihydro
quinoxaline
trifluoromethyl
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE4329970A
Other languages
German (de)
English (en)
Inventor
Hans-Joerg Dr Treiber
Berthold Dr Behl
Hans Peter Dr Hofmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Priority to DE4329970A priority Critical patent/DE4329970A1/de
Priority to PL94310950A priority patent/PL310950A1/xx
Priority to DE59407285T priority patent/DE59407285D1/de
Priority to EP94911932A priority patent/EP0691970B1/de
Priority to AU64282/94A priority patent/AU6428294A/en
Priority to CA002158167A priority patent/CA2158167A1/en
Priority to HU9502848A priority patent/HUT73970A/hu
Priority to FI954614A priority patent/FI954614A7/fi
Priority to AT94911932T priority patent/ATE173263T1/de
Priority to JP6521617A priority patent/JPH08508271A/ja
Priority to KR1019950704226A priority patent/KR960701874A/ko
Priority to BR9406034A priority patent/BR9406034A/pt
Priority to SI9420023A priority patent/SI9420023A/sl
Priority to CZ952464A priority patent/CZ246495A3/cs
Priority to PCT/EP1994/000871 priority patent/WO1994022865A1/de
Priority to NZ263552A priority patent/NZ263552A/en
Priority to CN94191613A priority patent/CN1041928C/zh
Priority to IL109076A priority patent/IL109076A/xx
Priority to TW083102796A priority patent/TW291478B/zh
Priority to HRP4329970.9A priority patent/HRP940210A2/xx
Publication of DE4329970A1 publication Critical patent/DE4329970A1/de
Priority to NO953892A priority patent/NO953892L/no
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE4329970A 1993-03-31 1993-09-04 Neue Imidazolo-chinoxalinone, ihre Hestellung und Verwendung Withdrawn DE4329970A1 (de)

Priority Applications (21)

Application Number Priority Date Filing Date Title
DE4329970A DE4329970A1 (de) 1993-03-31 1993-09-04 Neue Imidazolo-chinoxalinone, ihre Hestellung und Verwendung
SI9420023A SI9420023A (en) 1993-03-31 1994-03-19 Imidazoloquinoxalinone derivatives as eaa antagonists
BR9406034A BR9406034A (pt) 1993-03-31 1994-03-19 Derivados de imidazoloquinoxalinonas como antagonistas de eaa.
EP94911932A EP0691970B1 (de) 1993-03-31 1994-03-19 Imidazolochinoxalinonderivate als eaa antagonisten
AU64282/94A AU6428294A (en) 1993-03-31 1994-03-19 Imidazoloquinoxalinone derivatives as eaa antagonists
CA002158167A CA2158167A1 (en) 1993-03-31 1994-03-19 Novel imidazoloquinoxalinones, their preparation and use
HU9502848A HUT73970A (en) 1993-03-31 1994-03-19 Imidazoloquinoxalinone derivatives, process for preparing them and pharmaceutical compositions of eaa antagonistic activity containing them
FI954614A FI954614A7 (fi) 1993-03-31 1994-03-19 Imidatsolokinoksalinonijohdannaiset EAA-antagonisteina
AT94911932T ATE173263T1 (de) 1993-03-31 1994-03-19 Imidazolochinoxalinonderivate als eaa antagonisten
JP6521617A JPH08508271A (ja) 1993-03-31 1994-03-19 Ｅａａ拮抗体としてのイミダゾロキノキサリノン誘導体
CZ952464A CZ246495A3 (en) 1993-03-31 1994-03-19 Imidazolequinoline derivative as eaa antagonist
PL94310950A PL310950A1 (en) 1993-03-31 1994-03-19 Novel imidazole quinoxalinones, method of obtaining them and their application
DE59407285T DE59407285D1 (de) 1993-03-31 1994-03-19 Imidazolochinoxalinonderivate als eaa antagonisten
KR1019950704226A KR960701874A (ko) 1993-03-31 1994-03-19 신규한 이미다졸로-퀴녹살리논, 그들의 제조 방법 및 용도(Novel Imidazolo Quinoxalinones, Their Preparation and Use)
PCT/EP1994/000871 WO1994022865A1 (de) 1993-03-31 1994-03-19 Imidazolochinoxalinonderivate als eaa antagonisten
NZ263552A NZ263552A (en) 1993-03-31 1994-03-19 4,5-dihydro-4-oxoimidazolo[1,2-a]quinoxaline derivatives
CN94191613A CN1041928C (zh) 1993-03-31 1994-03-19 新的咪唑并喹喔啉酮及其制备方法和用途
IL109076A IL109076A (en) 1993-03-31 1994-03-22 2-SUBSTITUTED 4,5-DIHYDROIMIDAZOLO £1,2-a| QUINOXALIN-4-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
TW083102796A TW291478B (enExample) 1993-03-31 1994-03-30
HRP4329970.9A HRP940210A2 (en) 1993-03-31 1994-03-30 New imidazoloquinoxalinones their production and use
NO953892A NO953892L (no) 1993-03-31 1995-09-29 Imidazolokinoksalinon-derivater som EAA-antagonister

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4310521 1993-03-31
DE4329970A DE4329970A1 (de) 1993-03-31 1993-09-04 Neue Imidazolo-chinoxalinone, ihre Hestellung und Verwendung

Publications (1)

Publication Number Publication Date
DE4329970A1 true DE4329970A1 (de) 1994-10-06

Family

ID=6484365

Family Applications (2)

Application Number Title Priority Date Filing Date
DE4329970A Withdrawn DE4329970A1 (de) 1993-03-31 1993-09-04 Neue Imidazolo-chinoxalinone, ihre Hestellung und Verwendung
DE59407285T Expired - Fee Related DE59407285D1 (de) 1993-03-31 1994-03-19 Imidazolochinoxalinonderivate als eaa antagonisten

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE59407285T Expired - Fee Related DE59407285D1 (de) 1993-03-31 1994-03-19 Imidazolochinoxalinonderivate als eaa antagonisten

Country Status (4)

Country Link
KR (1) KR960701874A (enExample)
DE (2) DE4329970A1 (enExample)
TW (1) TW291478B (enExample)
ZA (1) ZA942246B (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19510965A1 (de) * 1995-03-24 1996-09-26 Asta Medica Ag Neue Pyrido/3,2-e/pyrazinone mit antiasthmatischer Wirksamkeit und Verfahren zu deren Herstellung
US5741785A (en) * 1994-02-11 1998-04-21 Novo Nordisk A/S Heterocyclic compounds, their preparation and use
US7485640B2 (en) * 2002-11-06 2009-02-03 Merck Sharp & Dohme Limited Imidazopyrazinones as GABA-A receptor anxiolytics

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5741785A (en) * 1994-02-11 1998-04-21 Novo Nordisk A/S Heterocyclic compounds, their preparation and use
DE19510965A1 (de) * 1995-03-24 1996-09-26 Asta Medica Ag Neue Pyrido/3,2-e/pyrazinone mit antiasthmatischer Wirksamkeit und Verfahren zu deren Herstellung
AU697908B2 (en) * 1995-03-24 1998-10-22 Asta Medica Aktiengesellschaft Novel pyrido(3,2-e)pyrazinones with anti-asthmatic action and processes for their manufacture
RU2143433C1 (ru) * 1995-03-24 1999-12-27 Аста Медика Акциенгезельшафт Пиридо[3,2-е]пиразиноны, способы их получения, препарат на их основе и способ получения препарата
US7485640B2 (en) * 2002-11-06 2009-02-03 Merck Sharp & Dohme Limited Imidazopyrazinones as GABA-A receptor anxiolytics

Also Published As

Publication number Publication date
DE59407285D1 (de) 1998-12-17
TW291478B (enExample) 1996-11-21
ZA942246B (en) 1995-10-02
KR960701874A (ko) 1996-03-28

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