DE3874019T2 - Verfahren zur konservierung von transplantierbaren, in vitro kultivierten epithelgeweben. - Google Patents

Verfahren zur konservierung von transplantierbaren, in vitro kultivierten epithelgeweben.

Info

Publication number
DE3874019T2
DE3874019T2 DE8888109528T DE3874019T DE3874019T2 DE 3874019 T2 DE3874019 T2 DE 3874019T2 DE 8888109528 T DE8888109528 T DE 8888109528T DE 3874019 T DE3874019 T DE 3874019T DE 3874019 T2 DE3874019 T2 DE 3874019T2
Authority
DE
Germany
Prior art keywords
epithelic
transplantable
preservation
vitro
cultivated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888109528T
Other languages
English (en)
Other versions
DE3874019D1 (de
Inventor
Ranieri Cancedda
Luca Michele De
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Istituto Nazionale per la Ricerca Sul Cancro
Original Assignee
Istituto Nazionale per la Ricerca Sul Cancro
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Istituto Nazionale per la Ricerca Sul Cancro filed Critical Istituto Nazionale per la Ricerca Sul Cancro
Application granted granted Critical
Publication of DE3874019D1 publication Critical patent/DE3874019D1/de
Publication of DE3874019T2 publication Critical patent/DE3874019T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0278Physical preservation processes
    • A01N1/0284Temperature processes, i.e. using a designated change in temperature over time
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0205Chemical aspects
    • A01N1/021Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0221Freeze-process protecting agents, i.e. substances protecting cells from effects of the physical process, e.g. cryoprotectants, osmolarity regulators like oncotic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/10Hair or skin implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60Materials for use in artificial skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Transplantation (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Environmental Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dentistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE8888109528T 1987-06-23 1988-06-15 Verfahren zur konservierung von transplantierbaren, in vitro kultivierten epithelgeweben. Expired - Fee Related DE3874019T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8721005A IT1207525B (it) 1987-06-23 1987-06-23 Metodo per la preservazione difogli trapiantabili di epitelio coltivato in vitro vitale.

Publications (2)

Publication Number Publication Date
DE3874019D1 DE3874019D1 (de) 1992-10-01
DE3874019T2 true DE3874019T2 (de) 1993-01-21

Family

ID=11175297

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888109528T Expired - Fee Related DE3874019T2 (de) 1987-06-23 1988-06-15 Verfahren zur konservierung von transplantierbaren, in vitro kultivierten epithelgeweben.

Country Status (25)

Country Link
US (1) US5298417A (de)
EP (1) EP0296475B1 (de)
JP (1) JP2644024B2 (de)
KR (1) KR960009482B1 (de)
AR (1) AR240061A1 (de)
AT (1) ATE79720T1 (de)
AU (1) AU618012B2 (de)
BR (1) BR8807104A (de)
CA (1) CA1330541C (de)
DE (1) DE3874019T2 (de)
DK (1) DK81789D0 (de)
ES (1) ES2034034T3 (de)
FI (1) FI94147C (de)
GR (1) GR3006069T3 (de)
HU (1) HU203827B (de)
IE (1) IE61449B1 (de)
IL (1) IL86806A (de)
IN (1) IN167396B (de)
IT (1) IT1207525B (de)
MX (1) MX11997A (de)
NO (1) NO177211C (de)
OA (1) OA09038A (de)
PT (1) PT87789B (de)
WO (1) WO1988010068A1 (de)
ZA (1) ZA884455B (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5482834A (en) * 1982-05-17 1996-01-09 Hahnemann University Evaluation of nucleic acids in a biological sample hybridization in a solution of chaotrophic salt solubilized cells
US5171660A (en) * 1989-04-26 1992-12-15 Cryolife, Inc. Process of revitalizing cells and tissue prior to cryopreservation
DE3941873A1 (de) * 1989-12-19 1991-06-20 Jakob Dr Bodziony Hohlfaser mit der beschichtung von zellen, die mehrjaehrige implantation in arterien und venen ermoeglichen
US5100676A (en) * 1990-02-02 1992-03-31 Biosurface Technology, Inc. Cool storage of cultured epithelial sheets
DE4012079C2 (de) * 1990-04-14 1997-11-06 Jakob Dr Bodziony Implantierbare Austausch- und Diffusionskammer
US5145770A (en) * 1990-06-04 1992-09-08 Biosurface Technology, Inc. Cryopreservation of cultured epithelial sheets
US5192312A (en) * 1991-03-05 1993-03-09 Colorado State University Research Foundation Treated tissue for implantation and methods of treatment and use
US6126935A (en) * 1991-11-20 2000-10-03 N.V. Innogenetics S.A. Pellets obtained from cell cultures of keratinocytes and their use in wound healing
US6585969B1 (en) 1991-11-20 2003-07-01 N. V. Innogenetics S.A. Non-viable keratinocyte cell composition or lysate for promoting wound healing
JPH0646840A (ja) * 1992-08-04 1994-02-22 Nippon Zenyaku Kogyo Kk 細胞凍結保存液
IT1263023B (it) * 1992-11-09 1996-07-23 Biostruttura epitelio-supporto tubulare e metodo per la sua preparazione.
IT1256621B (it) * 1992-12-04 1995-12-12 Soluzioni crioprotettrici
US5891617A (en) * 1993-09-15 1999-04-06 Organogenesis Inc. Cryopreservation of harvested skin and cultured skin or cornea equivalents by slow freezing
US5518878A (en) * 1993-09-15 1996-05-21 Organogenesis Inc. Cryopreservation of cultured skin or cornea equivalents with agitation
WO1995024873A1 (en) * 1994-03-14 1995-09-21 Cryolife, Inc. Treated tissue for implantation and preparation methods
DK0790767T3 (da) * 1994-11-09 2002-02-04 Celadon Science Llc Forbindinger til opheling af sår og fremgangsmåder til deres konservering
US5689961A (en) 1996-01-30 1997-11-25 Organogenesis Inc. Ice seeding apparatus for cryopreservation systems
AU6242298A (en) 1997-01-17 1998-08-07 Celadon Science, Llc Methods for promoting healing of corneal resurfacing wounds
US6713084B1 (en) * 1997-01-17 2004-03-30 Celadon Science, Llc Methods for promoting healing of skin resurfacing wounds
CA2404007A1 (en) * 2000-03-24 2002-09-23 Menicon Co., Ltd. Method for cyropreservation of tissue equivalent and cyropreserved tissue equivalent
WO2002058588A2 (en) 2000-12-27 2002-08-01 Ortec International, Inc. Processes for making cryopreserved composite living constructs and products resulting therefrom
DE10151296A1 (de) 2001-10-17 2003-04-30 Boehringer Ingelheim Pharma Keratinozyten verwendbar als biologisch aktive Substanz bei der Behandlung von Wunden
NZ534428A (en) * 2002-01-31 2006-12-22 Asahi Techno Glass Corp A cryopreservation method for primate embryonic stem cells using a cryopreservation medium comprising a cryoprotectant at a concentration of from 12% (w/v) to 50% (w/v)
US20060166360A1 (en) * 2002-10-18 2006-07-27 The General Hospital Corporation Compositions, solutions, and methods used for transplantation
US20070185238A1 (en) * 2006-02-06 2007-08-09 No-Burn Investments, Llc Paint with mold inhibitor and insecticide
CA2644091C (en) * 2008-10-20 2015-12-15 University Of Guelph Embryo culture media containing thyroid hormone
EP2854824A1 (de) 2012-05-25 2015-04-08 Boehringer Ingelheim International GmbH Verwendung von keratinozyten als einer biologisch aktive substanz in der behandlung von wunden wie diabätische wunden, gegebenenfalls in kombination mit einem dpp-4-hemmer
JP6581655B2 (ja) 2014-10-14 2019-09-25 フジフィルム セルラー ダイナミクス,インコーポレイテッド 多能性幹細胞由来ケラチノサイトの生成およびケラチノサイト培養の維持

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1395002A (fr) * 1963-03-01 1965-04-09 Union Carbide Corp Procédé de conservation de cellules
US3943993A (en) * 1974-05-03 1976-03-16 Smith Kendall O Low temperature storage of surface attached living cell cultures
US3940943A (en) * 1975-01-22 1976-03-02 The Curators Of The University Of Missouri Multistage freezing system for preservation of biological materials
US4016036A (en) * 1975-11-14 1977-04-05 Massachusetts Institute Of Technology Process for serially culturing keratinocytes
DE2715887A1 (de) * 1977-04-09 1978-10-12 Ayguen Suerayya Tahsin Prof Dr Verfahren zur herstellung und konservierung von human-zellkulturen aus menschlichen foeten sowie nach diesem verfahren hergestellte human-zellkulturen fuer die intravenoese oder intramuskulaere anwendung beim menschlichen koerper
US4456687A (en) * 1978-11-16 1984-06-26 President And Fellows Of Harvard College Agents for promoting growth of epithelial cells
DE2967509D1 (en) * 1978-12-26 1985-10-10 Massachusetts Inst Technology Skin-equivalent
JPS6029471B2 (ja) * 1979-08-16 1985-07-10 日機装株式会社 肝細胞の凍結方法
US4304866A (en) * 1979-11-14 1981-12-08 Massachusetts Institute Of Technology Transplantable sheets of living keratinous tissue
FR2493662A1 (fr) * 1980-11-05 1982-05-07 Rhone Poulenc Ind Substrats metallises pour circuits imprimes et leur procede de preparation
US4673649A (en) * 1983-07-15 1987-06-16 University Patents, Inc. Process and defined medium for growth of human epidermal keratinocyte cells
CA2000181A1 (en) * 1988-10-14 1990-04-14 Chung-Faye Chao Process for producing cultured epidermal sheet, product and method of use

Also Published As

Publication number Publication date
IN167396B (de) 1990-10-20
IE881889L (en) 1988-12-23
PT87789A (pt) 1989-05-31
FI94147B (fi) 1995-04-13
BR8807104A (pt) 1989-10-17
IT1207525B (it) 1989-05-25
DK81789A (da) 1989-02-22
IL86806A (en) 1992-02-16
ES2034034T3 (es) 1993-04-01
ATE79720T1 (de) 1992-09-15
CA1330541C (en) 1994-07-05
KR960009482B1 (en) 1996-07-20
FI94147C (fi) 1995-07-25
IE61449B1 (en) 1994-11-02
WO1988010068A1 (en) 1988-12-29
AU1995788A (en) 1989-01-19
JPH02500800A (ja) 1990-03-22
GR3006069T3 (de) 1993-06-21
HU203827B (en) 1991-10-28
AU618012B2 (en) 1991-12-12
EP0296475A1 (de) 1988-12-28
US5298417A (en) 1994-03-29
ZA884455B (en) 1989-03-29
AR240061A1 (es) 1990-01-31
EP0296475B1 (de) 1992-08-26
PT87789B (pt) 1994-11-30
NO890715D0 (no) 1989-02-20
MX11997A (es) 1993-06-01
DK81789D0 (da) 1989-02-22
NO177211C (no) 1995-08-09
HUT51848A (en) 1990-06-28
IT8721005A0 (it) 1987-06-23
OA09038A (de) 1991-03-31
FI890821A0 (fi) 1989-02-21
NO890715L (no) 1989-02-20
JP2644024B2 (ja) 1997-08-25
DE3874019D1 (de) 1992-10-01
NO177211B (no) 1995-05-02
FI890821A (fi) 1989-02-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee