DE3855814D1 - Chemische sensoren mit katalytischen antikörpern - Google Patents

Chemische sensoren mit katalytischen antikörpern

Info

Publication number
DE3855814D1
DE3855814D1 DE3855814T DE3855814T DE3855814D1 DE 3855814 D1 DE3855814 D1 DE 3855814D1 DE 3855814 T DE3855814 T DE 3855814T DE 3855814 T DE3855814 T DE 3855814T DE 3855814 D1 DE3855814 D1 DE 3855814D1
Authority
DE
Germany
Prior art keywords
membrane
chemical sensors
catalytic antibodies
spacer material
glass tube
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3855814T
Other languages
English (en)
Other versions
DE3855814T2 (de
Inventor
Gary Blackburn
Charles Durfor
Michael Powell
Richard Massey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IGEN International Inc
Original Assignee
IGEN Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IGEN Inc filed Critical IGEN Inc
Application granted granted Critical
Publication of DE3855814D1 publication Critical patent/DE3855814D1/de
Publication of DE3855814T2 publication Critical patent/DE3855814T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0002—Antibodies with enzymatic activity, e.g. abzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analyzing Materials Using Thermal Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
DE3855814T 1987-12-24 1988-12-12 Chemische sensoren mit katalytischen antikörpern Expired - Fee Related DE3855814T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13854287A 1987-12-24 1987-12-24
PCT/US1988/004426 WO1989005977A1 (en) 1987-12-24 1988-12-12 Chemical sensors employing catalytic antibodies

Publications (2)

Publication Number Publication Date
DE3855814D1 true DE3855814D1 (de) 1997-04-10
DE3855814T2 DE3855814T2 (de) 1997-10-02

Family

ID=22482503

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3855814T Expired - Fee Related DE3855814T2 (de) 1987-12-24 1988-12-12 Chemische sensoren mit katalytischen antikörpern

Country Status (10)

Country Link
EP (1) EP0362304B1 (de)
JP (1) JP2662542B2 (de)
KR (1) KR0144002B1 (de)
AT (1) ATE149687T1 (de)
AU (2) AU2949689A (de)
CA (1) CA1308021C (de)
DE (1) DE3855814T2 (de)
IL (1) IL88751A (de)
WO (1) WO1989005977A1 (de)
ZA (1) ZA889546B (de)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3916432A1 (de) * 1989-05-20 1990-11-22 Cammann Karl Verfahren und vorrichtung zur konzentrationsbestimmung eines antikoerper-antigenpaares
US5328847A (en) * 1990-02-20 1994-07-12 Case George D Thin membrane sensor with biochemical switch
US5494831A (en) * 1993-08-30 1996-02-27 Hughes Aircraft Company Electrochemical immunosensor system and methods
US5705399A (en) * 1994-05-20 1998-01-06 The Cooper Union For Advancement Of Science And Art Sensor and method for detecting predetermined chemical species in solution
CZ299135B6 (cs) * 1995-03-10 2008-04-30 Meso Scale Technologies, Llc. Corporation Servicecompany Kazeta a zarízení pro použití pri detekci analytu, zpusob provádení testu za použití uvedené kazety, kit pro použití pri provádení množiny elektrochemiluminescencních testu a zpusob detekce nebo merení analytu
WO1996038726A1 (en) * 1995-05-30 1996-12-05 Ecole Polytechnique Federale De Lausanne (Epfl) Covalently immobilized phospholipid bilayers on solid surfaces
JP2002515965A (ja) * 1995-08-18 2002-05-28 ダブリュー． ランドリ，ドナルド 抗体触媒反応の調節による有機化合物の検出
FR2746924B1 (fr) * 1996-03-29 1998-06-05 Indicia Diagnostics Dispositif de detection d'une substance d'interet dans un fluide et procede d'utilisation
ATE239905T1 (de) * 1996-06-20 2003-05-15 Univ New York Bestimmung von ligand-wechselwirkung mit einem polymermaterial
JP3612675B2 (ja) * 1997-06-05 2005-01-19 日本光電工業株式会社 ｐＨ変化誘因性物質または生物体の測定装置及び測定方法
DE19753056A1 (de) * 1997-11-29 1999-08-05 Wolfbeis Otto S Prof Dr Künstliche Oberfläche mit vorbestimmter Affinität
GB9805014D0 (en) * 1998-03-11 1998-05-06 Siemens Plc Improved mechanical arrangement for water quality measuring apparatus
EP0962773A1 (de) * 1998-06-03 1999-12-08 Mark Howard Jones Prüfverfahren, Vorrichtung und Markierungsmittel basierend auf Elektrochemie
JP2001083162A (ja) * 1999-09-17 2001-03-30 Fuji Photo Film Co Ltd 膜状生体高分子吸着材及び吸着用キット
JP4505776B2 (ja) * 2001-01-19 2010-07-21 凸版印刷株式会社 遺伝子検出システム、これを備えた遺伝子検出装置、検出方法、並びに遺伝子検出用チップ
CA3081228C (en) 2001-09-10 2022-02-15 Meso Scale Technologies, Llc Assay buffer, compositions containing the same, and methods of using the same
DE10163640A1 (de) * 2001-12-21 2003-07-03 Arno Kromminga Nachweis von Wechselwirkungen zwischen mindestens zwei spezifischen Biomolekülen
JP3918622B2 (ja) * 2002-04-23 2007-05-23 アイシン精機株式会社 微小物質誘導装置
DE10239290B3 (de) * 2002-08-27 2004-04-08 Dornier Medtech Systems Gmbh Hochsensitiver Biosensor durch Aktivierung der erkennenden Komponente
JP2004245613A (ja) * 2003-02-12 2004-09-02 Japan Science & Technology Agency フロ−セル型ｑｃｍ装置および試料測定方法
GB0308324D0 (en) * 2003-04-10 2003-05-14 Piezoptic Ltd A chemical sensing device
US7723099B2 (en) 2003-09-10 2010-05-25 Abbott Point Of Care Inc. Immunoassay device with immuno-reference electrode
GB0609060D0 (en) * 2006-05-08 2006-06-14 Panopsys Ltd A chemical sensing device
WO2009105709A1 (en) 2008-02-21 2009-08-27 Dexcom, Inc. Systems and methods for processing, transmitting and displaying sensor data
US8583204B2 (en) 2008-03-28 2013-11-12 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US11730407B2 (en) 2008-03-28 2023-08-22 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US8682408B2 (en) 2008-03-28 2014-03-25 Dexcom, Inc. Polymer membranes for continuous analyte sensors
WO2010134505A1 (ja) * 2009-05-18 2010-11-25 日本電気株式会社 抗マラリア薬の免疫センサおよびその製造方法
WO2010134506A1 (ja) * 2009-05-18 2010-11-25 日本電気株式会社 爆発物検出用の免疫センサおよびその製造方法
US20110027458A1 (en) 2009-07-02 2011-02-03 Dexcom, Inc. Continuous analyte sensors and methods of making same
US9351677B2 (en) 2009-07-02 2016-05-31 Dexcom, Inc. Analyte sensor with increased reference capacity
JP6046058B2 (ja) * 2011-03-04 2016-12-14 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 可逆的なイオン及び分子検出又は移動用ナノポアデバイス
ES2606154T3 (es) * 2011-11-23 2017-03-23 The Governing Council Of The University Of Toronto Biosensor versátil y sensible
CN102636463A (zh) * 2012-04-24 2012-08-15 攀钢集团攀枝花钢铁研究院有限公司 硫酸氧钛水解的在线检测装置及控制设备
KR101420916B1 (ko) * 2012-05-22 2014-07-17 한양대학교 산학협력단 세포 계수 장치 및 세포 계수 방법
US10278624B2 (en) * 2013-05-23 2019-05-07 Iphenotype Llc Method and system for maintaining or improving wellness
US9341639B2 (en) 2013-07-26 2016-05-17 Industrial Technology Research Institute Apparatus for microfluid detection
BR112017004896B8 (pt) 2014-09-12 2024-01-02 Trividia Health Inc Sistema para medir propriedade de amostra em líquido, tira de teste de diagnóstico e método para medir concentração de glicose em amostra de sangue
WO2017059337A1 (en) * 2015-10-02 2017-04-06 Georgetown University High-resolution in situ electrochemical nmr with interdigitated electrodes
WO2017123781A1 (en) * 2016-01-12 2017-07-20 Ambergen, Inc. Proteome-wide drug screening using mass spectrometric imaging (msi) of bead-arrays
CN106290469B (zh) * 2016-09-29 2023-06-20 中国石油大学(华东) 一种油气井燃爆压裂药剂高温高压安全性测试装置及其使用方法
US20190285576A1 (en) 2016-10-24 2019-09-19 Toray Industries, Inc. Semiconductor sensor, method for producing the same, and combined sensor
JP7017727B2 (ja) * 2017-06-05 2022-02-09 島根県 味覚センサ
JP2019039734A (ja) * 2017-08-24 2019-03-14 学校法人東北学院 イオン・バイオセンサチップとイオン・バイオセンサモジュールおよびこれらを用いたイオン・バイオセンサ
CN107884392B (zh) * 2017-10-24 2020-09-18 中国航天空气动力技术研究院 电弧加热器气流焓值光谱测量系统
CN113348526B (zh) 2019-02-05 2023-03-14 日立金属株式会社 卷绕磁芯、合金芯以及卷绕磁芯的制造方法
JP2021117172A (ja) * 2020-01-29 2021-08-10 三菱マテリアル株式会社 バイオセンサ

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2540508B2 (ja) * 1983-11-29 1996-10-02 イージエン・インコーポレイテッド 化学反応を触媒する方法
US4659567A (en) * 1984-09-07 1987-04-21 Scripps Clinic & Research Foundation Molecules with antibody combining sites that bind to hydrolytic transition states
ZA893106B (en) * 1988-04-29 1990-01-31 Igen Inc Interaction system comprising a surfactant-stabilized disperse aqueous phase containing an antibody or antibody fragment

Also Published As

Publication number Publication date
JPH02501860A (ja) 1990-06-21
IL88751A0 (en) 1989-07-31
DE3855814T2 (de) 1997-10-02
AU2949689A (en) 1989-07-19
ATE149687T1 (de) 1997-03-15
EP0362304A1 (de) 1990-04-11
CA1308021C (en) 1992-09-29
EP0362304B1 (de) 1997-03-05
KR0144002B1 (ko) 1998-07-15
EP0362304A4 (en) 1991-04-10
IL88751A (en) 1994-06-24
AU669758B2 (en) 1996-06-20
WO1989005977A1 (en) 1989-06-29
JP2662542B2 (ja) 1997-10-15
KR900700882A (ko) 1990-08-17
ZA889546B (en) 1990-08-29
AU5311094A (en) 1994-03-10

Similar Documents

Publication Publication Date Title
ATE149687T1 (de) Chemische sensoren mit katalytischen antikörpern
EP2176659B1 (de) Mikrofluidische sensorkomplex-struktur
DE3852036D1 (de) Rezeptormembranen.
DK191088D0 (da) Glucoseelektrode og fremgangsmaade til glucosebestemmelse
JPS5626250A (en) Composite chemical sensor
DE69910003D1 (de) Überwachung physiologischer analyte
EP0396016A3 (de) Kontaminationsfreie Methode und Gerät zur Bestimmung chemischer Parameter einer Körperflüssigkeit
KR910003373A (ko) 미리 교정되고 사용후 폐기되는 전기화학적 감지기
NO951754D0 (no) Analysesystem for overvåkning av konsentrasjonen av en analytt i blodet til en pasient
DE69914319D1 (de) Signalverarbeitung zur messung von physiologischen analyten
JPH04290961A (ja) 迅速で簡単なマニュアルアッセイを行うためのデバイス
ATE86740T1 (de) Immunoenzymatisches testgeraet.
EP0467219A3 (en) Conductive sensors and their use in diagnostic assays
DE69033904D1 (de) Analysevorrichtung
DE3863637D1 (de) Rohrfoermiger piezo-elektrischer sensor mit grosser empfindlichkeit.
Gardies et al. Feasibility of an immunosensor based upon capacitance measurements
JP2591641B2 (ja) 微量アナライト物質の測定方法及び測定装置
GB2339281A (en) Immunoassay test strip
EP0185285A3 (de) Messapparat für Flüssigkeitspegel
Shiba et al. Liposome immunoelectrode
JPH01203962A (ja) 免疫化学的測定法
Sakai et al. Availability and development of an enzyme immunomicrosensor based on an ISFET for human immunoglobulins
JPH059740B2 (de)
JPS6469951A (en) Carbon dioxide gas detection indicator
SE8306050D0 (sv) Sensor for kemisk analys

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: IGEN INTERNATIONAL,INC.(N.D.GES.D.STAATES DELAWARE

8339 Ceased/non-payment of the annual fee