DE3825667C2 - - Google Patents

Info

Publication number
DE3825667C2
DE3825667C2 DE3825667A DE3825667A DE3825667C2 DE 3825667 C2 DE3825667 C2 DE 3825667C2 DE 3825667 A DE3825667 A DE 3825667A DE 3825667 A DE3825667 A DE 3825667A DE 3825667 C2 DE3825667 C2 DE 3825667C2
Authority
DE
Germany
Prior art keywords
imexon
proliferation
cell
induced
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3825667A
Other languages
German (de)
English (en)
Other versions
DE3825667A1 (de
Inventor
Uwe Prof. 6140 Bensheim De Bicker
Elmar Dr.Phil.Nat. 6940 Weinheim De Bosies
Rainer Dipl.-Chem. Dr.Rer.Nat. 6800 Mannheim De Haage
Dieter Dr.Med. 6900 Heidelberg De Herrmann
Wolfgang Dr.Rer.Nat. 6805 Heddesheim De Kampe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Priority to DE3825667A priority Critical patent/DE3825667A1/de
Priority to DE3844655A priority patent/DE3844655A1/de
Priority to DE58908926T priority patent/DE58908926D1/de
Priority to EP89113425A priority patent/EP0352652B1/de
Priority to DK198903633A priority patent/DK175199B1/da
Priority to PH38984A priority patent/PH26684A/en
Priority to AT89113425T priority patent/ATE117551T1/de
Priority to AU38877/89A priority patent/AU619027B2/en
Priority to CA000606620A priority patent/CA1333771C/en
Priority to HU893821A priority patent/HU206827B/hu
Priority to PT91293A priority patent/PT91293B/pt
Priority to IL9113889A priority patent/IL91138A/en
Priority to ZA895710A priority patent/ZA895710B/xx
Priority to IE244889A priority patent/IE66680B1/en
Priority to JP1194417A priority patent/JP2848634B2/ja
Priority to KR1019890010705A priority patent/KR0135757B1/ko
Publication of DE3825667A1 publication Critical patent/DE3825667A1/de
Application granted granted Critical
Publication of DE3825667C2 publication Critical patent/DE3825667C2/de
Priority to US08/026,210 priority patent/US5369119A/en
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Transplantation (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Prostheses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE3825667A 1988-07-28 1988-07-28 Verwendung von imexon als immunsuppressivum Granted DE3825667A1 (de)

Priority Applications (17)

Application Number Priority Date Filing Date Title
DE3825667A DE3825667A1 (de) 1988-07-28 1988-07-28 Verwendung von imexon als immunsuppressivum
DE3844655A DE3844655A1 (de) 1988-07-28 1988-07-28 Verwendung von imexon als immunsuppressivum
DE58908926T DE58908926D1 (de) 1988-07-28 1989-07-21 Verwendung von Imexon als Immunsuppressivum.
EP89113425A EP0352652B1 (de) 1988-07-28 1989-07-21 Verwendung von Imexon als Immunsuppressivum
DK198903633A DK175199B1 (da) 1988-07-28 1989-07-21 Anvendelse af imexon som immunsuppressivt middel
PH38984A PH26684A (en) 1988-07-28 1989-07-21 The use of imexone as an immune suppressive and pharmaceutical compositions containing them
AT89113425T ATE117551T1 (de) 1988-07-28 1989-07-21 Verwendung von imexon als immunsuppressivum.
AU38877/89A AU619027B2 (en) 1988-07-28 1989-07-24 Method for suppressing immune responses by administering imexon
CA000606620A CA1333771C (en) 1988-07-28 1989-07-25 Use of imexon as an immune suppressive and pharmaceutical compositions containing them
HU893821A HU206827B (en) 1988-07-28 1989-07-27 Process for producing pharmaceutical compositions containing imexone as active component with specifical immunosuppressive activity
PT91293A PT91293B (pt) 1988-07-28 1989-07-27 Processo para a preparacao de composicoes farmaceuticas com actividade imunossupressiva, contendo 4-imino-1,3-diazabiciclo -(3.1.0)-hexano-2-ona
IL9113889A IL91138A (en) 1988-07-28 1989-07-27 Immunosuppressive preparations containing Imaxon
ZA895710A ZA895710B (en) 1988-07-28 1989-07-27 The use of imexon as immune suppressive and pharmaceutical compositions containing imexon
IE244889A IE66680B1 (en) 1988-07-28 1989-07-27 The use of imexon as an immune suppressive
JP1194417A JP2848634B2 (ja) 1988-07-28 1989-07-28 免疫抑制作用を有する医薬
KR1019890010705A KR0135757B1 (ko) 1988-07-28 1989-07-28 이멕손을 포함하는 약학적 조성물
US08/026,210 US5369119A (en) 1988-07-28 1993-03-02 Use of imexon as an immune suppressive and pharmaceutical compositions containing imexon

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3825667A DE3825667A1 (de) 1988-07-28 1988-07-28 Verwendung von imexon als immunsuppressivum

Publications (2)

Publication Number Publication Date
DE3825667A1 DE3825667A1 (de) 1990-03-15
DE3825667C2 true DE3825667C2 (es) 1991-06-27

Family

ID=6359767

Family Applications (2)

Application Number Title Priority Date Filing Date
DE3825667A Granted DE3825667A1 (de) 1988-07-28 1988-07-28 Verwendung von imexon als immunsuppressivum
DE58908926T Expired - Fee Related DE58908926D1 (de) 1988-07-28 1989-07-21 Verwendung von Imexon als Immunsuppressivum.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE58908926T Expired - Fee Related DE58908926D1 (de) 1988-07-28 1989-07-21 Verwendung von Imexon als Immunsuppressivum.

Country Status (14)

Country Link
EP (1) EP0352652B1 (es)
JP (1) JP2848634B2 (es)
KR (1) KR0135757B1 (es)
AT (1) ATE117551T1 (es)
AU (1) AU619027B2 (es)
CA (1) CA1333771C (es)
DE (2) DE3825667A1 (es)
DK (1) DK175199B1 (es)
HU (1) HU206827B (es)
IE (1) IE66680B1 (es)
IL (1) IL91138A (es)
PH (1) PH26684A (es)
PT (1) PT91293B (es)
ZA (1) ZA895710B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA06006291A (es) * 2003-12-08 2006-08-23 Univ Arizona Composiciones anti-cancer sinergisticas.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2528460A1 (de) * 1975-06-26 1977-01-13 Boehringer Mannheim Gmbh Verwendung von l-carboxamido-2- cyan-aziridin als immunstimulans
DE2530398A1 (de) * 1975-07-08 1977-01-27 Boehringer Mannheim Gmbh Organische verbindung
DE2736296A1 (de) * 1977-08-12 1979-02-22 Boehringer Mannheim Gmbh Verwendung von 2-cyan-aziridin und seinen derivaten zur immunstimulierung

Also Published As

Publication number Publication date
DK363389D0 (da) 1989-07-21
PT91293B (pt) 1995-03-01
JP2848634B2 (ja) 1999-01-20
PH26684A (en) 1992-09-15
KR900001369A (ko) 1990-02-27
ZA895710B (en) 1990-04-25
IL91138A0 (en) 1990-03-19
DE58908926D1 (de) 1995-03-09
EP0352652A2 (de) 1990-01-31
PT91293A (pt) 1990-02-08
IE66680B1 (en) 1996-01-24
IL91138A (en) 1994-10-21
HUT52378A (en) 1990-07-28
AU3887789A (en) 1990-02-01
KR0135757B1 (ko) 1998-04-23
HU206827B (en) 1993-01-28
IE892448L (en) 1990-01-28
AU619027B2 (en) 1992-01-16
EP0352652B1 (de) 1995-01-25
EP0352652A3 (de) 1991-09-04
DE3825667A1 (de) 1990-03-15
DK363389A (da) 1990-01-29
JPH0288521A (ja) 1990-03-28
DK175199B1 (da) 2004-07-05
CA1333771C (en) 1995-01-03
ATE117551T1 (de) 1995-02-15

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DE3825667C2 (es)
DE3844839C2 (de) Verwendung von Imexon als Immunsuppressivum
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DE1792447C3 (de) Oral anwendbares, cytostatisches Mittel
DE3212909C2 (es)

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