DE3687870T2 - 2-oxa-isocephemverbindungen, sie enthaltende zusammensetzungen und verfahren zu deren herstellung. - Google Patents

2-oxa-isocephemverbindungen, sie enthaltende zusammensetzungen und verfahren zu deren herstellung.

Info

Publication number
DE3687870T2
DE3687870T2 DE8686112486T DE3687870T DE3687870T2 DE 3687870 T2 DE3687870 T2 DE 3687870T2 DE 8686112486 T DE8686112486 T DE 8686112486T DE 3687870 T DE3687870 T DE 3687870T DE 3687870 T2 DE3687870 T2 DE 3687870T2
Authority
DE
Germany
Prior art keywords
group
compound
alkyl
isocephem
thiomethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686112486T
Other languages
German (de)
English (en)
Other versions
DE3687870D1 (de
Inventor
Setsuro Alg De Blanche Fujii
Hiroshi Ishikawa
Koichiro Jitsukawa
Kimio Sudo
Sachio Toyama
Hidetsugu Tsubouchi
Kouichi Tsuji
Koichi Yasumura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE3687870D1 publication Critical patent/DE3687870D1/de
Publication of DE3687870T2 publication Critical patent/DE3687870T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE8686112486T 1985-09-09 1986-09-09 2-oxa-isocephemverbindungen, sie enthaltende zusammensetzungen und verfahren zu deren herstellung. Expired - Fee Related DE3687870T2 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP19904485 1985-09-09
JP28503185 1985-12-18
JP3441286 1986-02-18
JP7722986 1986-04-03
JP13297686 1986-06-09
JP16713486 1986-07-15

Publications (2)

Publication Number Publication Date
DE3687870D1 DE3687870D1 (de) 1993-04-08
DE3687870T2 true DE3687870T2 (de) 1993-08-19

Family

ID=27549724

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686112486T Expired - Fee Related DE3687870T2 (de) 1985-09-09 1986-09-09 2-oxa-isocephemverbindungen, sie enthaltende zusammensetzungen und verfahren zu deren herstellung.

Country Status (8)

Country Link
US (1) US4831026A (enExample)
EP (1) EP0215435B1 (enExample)
JP (1) JPS63152383A (enExample)
KR (2) KR940006634B1 (enExample)
AU (1) AU583419B2 (enExample)
DE (1) DE3687870T2 (enExample)
DK (1) DK429986A (enExample)
ES (1) ES2000907A6 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK123488A (da) * 1987-03-09 1988-09-10 Otsuka Pharma Co Ltd 2-oxa-isocephemforbindelser, praeparater indeholdende dem, og fremgangsmaader til fremstilling af dem
DK582788A (da) * 1987-10-22 1989-04-23 Otsuka Pharma Co Ltd 2-oxa-isocephemforbindelser, midler der indeholder dem og fremgangsmaader til fremstilling af dem
KR910011865A (ko) * 1989-12-29 1991-08-07 오쓰카 아키히코 세팔로스포린 유도체, 이를 함유하는 항균제 및 이의 제조방법
JP3007986B2 (ja) * 1990-03-02 2000-02-14 大塚化学株式会社 β―ラクタム誘導体の製法
AU645787B2 (en) * 1990-04-09 1994-01-27 Otsuka Pharmaceutical Co., Ltd. Cephalosporin derivatives, the process for preparing the same, and antimicrobial composition containing the derivatives
JPH08245635A (ja) * 1995-03-10 1996-09-24 Otsuka Chem Co Ltd ２−イソセフェム誘導体の製造法
JP3775820B2 (ja) * 1995-03-10 2006-05-17 大塚化学ホールディングス株式会社 ハロゲン化β−ラクタム化合物の製造法
ES2248840T3 (es) 1996-02-23 2006-03-16 Eli Lilly And Company Antagonistas de vasopresina v1a no peptidilicos.
PE20150775A1 (es) * 2012-10-29 2015-05-21 Hoffmann La Roche Derivados de oxazolidinona 3,4-disustituidos y su uso como inhibidores del canal de potasio activado por calcio

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4013648A (en) * 1975-07-23 1977-03-22 Bristol-Myers Company Δ2,3 -0-2-Isocephem-4-carboxylic acid and derivatives as antibacterial agents
DE2818263A1 (de) * 1978-04-26 1979-11-08 Bayer Ag Beta-lactamantibiotika
FR2472574A1 (fr) * 1979-12-24 1981-07-03 Ici Pharma Derives de cephalosporine et composition pharmaceutique les contenant
FR2505840A1 (fr) * 1981-05-13 1982-11-19 Roussel Uclaf Nouveaux produits derives de l'acide 2-amino thiazolyl 2-oxyimino acetamido bicyclo-octene carboxylique, leur procede de preparation et leur application comme medicaments
US4534898A (en) * 1982-07-23 1985-08-13 Merck & Co., Inc. 1-Oxa-1-dethia-cephalosporin derivatives

Also Published As

Publication number Publication date
US4831026A (en) 1989-05-16
EP0215435B1 (en) 1993-03-03
ES2000907A6 (es) 1988-03-16
KR880003953A (ko) 1988-06-01
EP0215435A1 (en) 1987-03-25
DK429986D0 (da) 1986-09-09
JPH0586954B2 (enExample) 1993-12-14
DK429986A (da) 1987-03-10
KR870003118A (ko) 1987-04-15
JPS63152383A (ja) 1988-06-24
AU6252786A (en) 1988-03-17
AU583419B2 (en) 1989-04-27
KR950008974B1 (ko) 1995-08-10
DE3687870D1 (de) 1993-04-08
KR940006634B1 (ko) 1994-07-23

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee